The Science of CRISPR

And the #NobelPrize2020 goes to…#CRISPR. Eight years after the discovery of this revolutionary technology, the field has made leaps and bounds in the application of this science. CRISPR is a pair of molecular scissors, that allows the precise editing of virtually any gene in the genome. Here's how it works. More videos coming soon. Please rate☝️, comment👇, and subscribe☝️ if you like them, so that I can make more! Please send through requests for topics to cover as well. What do you want to learn about? #scienceinmotion
Music thanks to:
Music by Adam Vitovský
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Creative Commons - Attribution 3.0 Unported - CC BY 3.0
Images thanks to:
Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Emmanuelle Charpentier & Jennifer Doudna. Adapted from WikiCommons. Available from:
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Creative Commons - Attribution 3.0 Unported - CC BY 3.0
Some images designed by Freepik/brgfx/Makyzz/vectorpouch/ upklyak. Available from: www.freepik.com
Germline modification regulations. The Conversation. Available from: theconversatio...
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Some images adapted from BioRender. Created with BioRender.com.
References:
Alagoz M, Kherad N. Advance genome editing technologies in the treatment of human diseases: CRISPR therapy (Review). Int J Mol Med. 2020;46(2):521-34.
Jiang F, Doudna JA. CRISPR-Cas9 Structures and Mechanisms. Annu Rev Biophys. 2017 May 22;46:505-529. doi: 10.1146/annurev-biophys-062215-010822. Epub 2017 Mar 30. PMID: 28375731.
Uddin F, Rudin CM, Sen T. CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future. Front Oncol. 2020;10:1387-.
Li H, Yang Y, Hong W, Huang M, Wu M, Zhao X. Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects. Signal Transduction and Targeted Therapy. 2020;5(1):1.
Araki M, Ishii T. International regulatory landscape and integration of corrective genome editing into in vitro fertilization. Reproductive Biology and Endocrinology. 2014;12(1):108.
Hsu Patrick D, Lander Eric S, Zhang F. Development and Applications of CRISPR-Cas9 for Genome Engineering. Cell. 2014;157(6):1262-78.

[@VCCCAlliance]

This is brilliant. Clear, highly professional and very interactive.

[@anj2005]

Really informative! 👍

[@punitaaran8061]

That’s very smart talk. Yes 🤝

[@e.v.k.3632]

There is nothing more interesting than that

[@lucyk2371]

Anyone ever seen the movie Gattaca? I've heard that we already have laws to prevent this. Is this true? Great movie about genetic engineering based discrimination. It was ahead of its time.

[@lucyk2371]

We need this to find a cure for cancer. Why can't we use it like an in utero vaccination against cancer, etc. We need to study this as much as possible.