Spinocerebellar ataxia - causes, symptoms, diagnosis, treatment, pathology

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  • Опубліковано 29 гру 2024

КОМЕНТАРІ • 120

  • @mooneysonthemove283
    @mooneysonthemove283 3 місяці тому +5

    I was diagnosed with this awful condition over 15 years ago and at times it’s very discouraging and has me wanting to sink in my chair and let life pass me by. And the sad thing about it is, it can be so depressing at times that you don’t want to do anything which is the worst thing you can do when trying to manage the symptoms. It’s like, when you rest your body, you have to relearn how to walk. But I say, keep fighting the fight!

  • @NiraiRaipi
    @NiraiRaipi 4 роки тому +86

    1 litre of tears.. An inspiring Japanese dorama about the story of a young girl's struggle with this disease..

    • @areejps
      @areejps 4 роки тому +12

      i am here because of this drama too

    • @inosuke3613
      @inosuke3613 4 роки тому +4

      @@areejps same

    • @fetchan28
      @fetchan28 3 роки тому +2

      @@areejps same :" that dorama was so good :"

    • @jenecacraco3477
      @jenecacraco3477 3 роки тому

      same here..i want to understand it more

    • @olympiath3768
      @olympiath3768 3 роки тому +1

      Which is that story? Title please?

  • @NoobAllert
    @NoobAllert 2 роки тому +3

    Guys seriosly, ive loved Osmosis since the beggining of my med school, you guys help me so much on understanding things in a simpler way

    • @osmosis
      @osmosis  2 роки тому +2

      Glad to be part of your medical studies! 🥰❤️🙏🏼

  • @feliciaherrera1211
    @feliciaherrera1211 4 роки тому +19

    Treatment also includes occupational therapy

  • @gardenlifelove9815
    @gardenlifelove9815 2 роки тому +8

    There are a couple of famous UA-cam physical therapists that are well loved that one of them has recently been diagnosed with this condition. His speech is very affe Ted bit he does on and recently came on to explain this disease.

  • @NAMAHE
    @NAMAHE 4 роки тому +16

    this is such a horrible dicease. i saw my father (not my real father, but the father of my half sister, and the father i grew up with) decline and stuggle with it until he died last year, 65 years old. he was in a wheel chair, blind and had no short term memory for the last 10 years. i saw an outgoing social entreprenour deteriorate little by little, becoming a shell of the person he used to be. he fought so hard until the very end. we don't know if my little sister has it, and i don't think she wants to take a test to find out. i don't believe in god, but i pray that there will be a cure for this soon. i wouldn't wish this on my worst enemy.

    • @cindylou5673
      @cindylou5673 3 роки тому +2

      Do a lot of praying because that's what it takes. Believe in yourself if nothing else and continue to pray...

    • @eishakhalid345
      @eishakhalid345 3 роки тому

      Same thing with my mom :( she passed away

    • @NAMAHE
      @NAMAHE 3 роки тому

      @@eishakhalid345 i'm so sorry.. may she rest in peace.

    • @aman7454
      @aman7454 3 роки тому

      @@eishakhalid345 RIP

    • @amberidk5096
      @amberidk5096 3 роки тому

      My mom has it too … sca 17 and There is 50% chance i have it too … on one side I want to know if I have it too but on the other side I am also afraid to know what the test results may be ( i am now 15 and my mom is 45 btw… the symptoms begun 14 years ago)

  • @CrazyBluJay
    @CrazyBluJay Місяць тому

    I am SO HAPPY I came across this channel. I have always taken intrest in the medical field. I tried to use Google but it wouldn't always give a good example on what I'm looking for.

  • @JHuiYi16
    @JHuiYi16 2 роки тому +14

    Psychiatric/psychology therapy is also very important as these patients tend to fall into depression. My dad had it and gave up on life :(

    • @osmosis
      @osmosis  2 роки тому

      Thanks for sharing and we're sorry to know about your dad. 🙏🏼

    • @SinfulScents
      @SinfulScents 10 місяців тому

      I’m very sorry!

    • @solidfuel0
      @solidfuel0 6 місяців тому

      But why not give up

    • @JHuiYi16
      @JHuiYi16 6 місяців тому

      @@solidfuel0 you are enough, you are worthy, just by simply existing.

    • @solidfuel0
      @solidfuel0 6 місяців тому

      @@JHuiYi16 worthy to who? All people are selfish

  • @Milamber7Pug
    @Milamber7Pug 3 роки тому +12

    Neuroimaging isn't a good way to diagnose. A significant number of people with well progressed symptoms can show no visible cerebellar atrophy.

    • @jimmcconnell7328
      @jimmcconnell7328 Рік тому

      If neuronimaging isn’t useful in diagnosis,what is? I have ET with balance issues seven years after diagnosis.

    • @janbarriault4494
      @janbarriault4494 Рік тому

      the history should make the diagnosis,, neuroimaging, investigations, then will confirm it.

  • @AmberTopps
    @AmberTopps 9 місяців тому +2

    We just found out my son has this disease and he got it from his fathers side and they said nothing while we were dating,my son also has 2 kids and we hope they dont have it.I also have a daughter and she just had a son and im hoping they are well

    • @josianemukasa3434
      @josianemukasa3434 2 місяці тому

      The best way is to get them have tested , my step son has got it from.his late mom and brother . It so 😢heartbreaking 💔 there is no cure for that, we tried stem cell nothing

  • @CrazyBluJay
    @CrazyBluJay Місяць тому

    Oh! I was wondering if you have a video explaining what makes a disease a disease, I always thought it was a form of sickness, but not involving genetics.

  • @thefenerbahcesk4156
    @thefenerbahcesk4156 4 роки тому +3

    I wonder if protein aggregation due to polyglutamine expansion is a possible mechanism for SCA, as with Huntington's Disease.

  • @sindhu7754
    @sindhu7754 2 роки тому +1

    Thank you so 🙏much outstanding explaination ✨before my exam

    • @osmosis
      @osmosis  2 роки тому

      We hope your exam went well, Sindhu! 😊

  • @shuvoislam8104
    @shuvoislam8104 4 роки тому +3

    Understand the problem with walking,co-ordination, eye movement due to cerebellum dysfunction but why is there speech problem??

    • @cindylou5673
      @cindylou5673 3 роки тому

      I think it has something to do with the vocal chords. I have not been diagnosed yet but have all the symptoms and I am starting to slur off and on. I have weird things about my throat...

  • @shraddhakanade951
    @shraddhakanade951 3 роки тому +2

    Thank you so much ✨

  • @raheebr2438
    @raheebr2438 4 роки тому +12

    Great explanation, as always!👍

  • @shanshancc
    @shanshancc 3 роки тому +4

    Hello, my friend has SCA type 3. This condition passed on to her from her mother who is now bed ridden patient . My friend's conditions currently are that she often cannot walk straight and on some bad days, she cannot even get up. Now she is 15-week pregnant and worried if this condition will pass on to here baby? Is there any way to test during pregnancy if her baby also has this condition? Thank you so much in advance for you answer.

    • @Decodecyber_help
      @Decodecyber_help 3 роки тому

      Thanks to Dr nafuar he cured me few months ago

    • @faisaltasiu5421
      @faisaltasiu5421 3 роки тому

      There’s is a herbal cure for ataxia thanks to dr nafuar on UA-cam now I’m perfectly cured and free from ataxia thanks dr nafuar

    • @Rajveergillcom
      @Rajveergillcom Рік тому +1

      Hereditary testing is available for pregnant mothers at 2nd month of pregnancy

  • @manuelperezruizdiaz9418
    @manuelperezruizdiaz9418 4 роки тому +2

    Outstanding explanation

  • @PtolemyXVII
    @PtolemyXVII 4 роки тому +10

    This is very interesting...especially since glutamine leads to GABA production, and inhibitory GABA transmission also leads to diseases like Parkinson's via ataxia and neurodegeneration and also epilepsy. So I'm wondering, because vitamin e deficient diets in animal studies have been shown to cause ataxia and neurodegeneration, could a deficiency in vitamin e lead to the expression of CAG repeats that could cause this condition and other related conditions? (Re: vitamin e changes glutamate and GABA inducing enzymes)

    • @abhishekvsmalyala
      @abhishekvsmalyala 4 роки тому +2

      This whole theory loses it's credibility as soon as you realize that Glutamate is ALWAYS a stimulatory neurotransmitter, unlike GABA.

    • @PtolemyXVII
      @PtolemyXVII 4 роки тому +1

      @@abhishekvsmalyala glutamate but not glutamine. glutamate is converted into glutamine by glutamine synthetase.

    • @PtolemyXVII
      @PtolemyXVII 4 роки тому +4

      @@abhishekvsmalyala I don't think that's accurate. Vitamin e would regulate glutamate which would alter the levels of glutamine in the cell - hence inhibiting GABA production..
      That's what I was proposing in my original post since this pathway has already been established, but hasn't been studied specifically for neurological diseases like Parkinson's or SCA.

    • @badrinaqvi8094
      @badrinaqvi8094 2 роки тому

      o

  • @medicos4health39
    @medicos4health39 4 роки тому +2

    great!! you have inspired me to make videos on youtube.

  • @googleuser1416
    @googleuser1416 5 місяців тому

    Is spinocerebellar ataxia the same as Friedreich's ataxia?

  • @dingdong436.
    @dingdong436. 2 роки тому +1

    Thank you osmosis a lot!❤❤❤

    • @osmosis
      @osmosis  2 роки тому

      Most welcome! 🙏🏼

  • @anandk3836
    @anandk3836 4 роки тому +2

    my brother has same problem (spainocerebullum degeneation) if any treatment plzz inform sir

  • @Mazeisaspace
    @Mazeisaspace 8 місяців тому

    what abour aquired ataxia?

  • @controluday6414
    @controluday6414 Рік тому

    Is it similar to Huntington's Disease/chorea ?

    • @vananhtran4994
      @vananhtran4994 11 місяців тому

      No, ataxia caused bt cerebellum is being damage or atrophy. While hungtington’s not

  • @Sarkar-148
    @Sarkar-148 3 роки тому +4

    Hello sir I am from India I have a patient her age about 29 years as like same problem with her low balance coordination shaking and pain the back side how to treat the cases ?? Plz help her.the doctor says not cure about this disease

    • @TheParamendra
      @TheParamendra 5 місяців тому

      I'm a patient of sca type 1, suffered 3 years very badly but with brahma vidya, astrology, yogas, diet and overall ayurvedic treatment I'm almost recovering.

  • @2579Mb
    @2579Mb 4 роки тому +1

    Even every video is mind blowing. I like yr video & as yr subscrber.

  • @026_mahesh3
    @026_mahesh3 2 роки тому

    Is spino cerebellar degeneration, spino cerebellar ataxia are same????????

    • @laululla
      @laululla Рік тому +1

      Not always. You can have cerebellar ataxia also from tumor or infarct, not only trough degeneration.

  • @nagulavenkateshwarlu6775
    @nagulavenkateshwarlu6775 2 роки тому +1

    My son is 3 years not walking till suffering with spino celebral ataxia 2

  • @Argnja
    @Argnja 3 роки тому

    робите аналіз на ген-сцатаксії?Робіть.

  • @HaiderAli-yk9ve
    @HaiderAli-yk9ve 4 роки тому +1

    Nice

  • @jimmyosman
    @jimmyosman 10 місяців тому

    the confusing things is,,i have this condition,,but just for my speech disorder,,my hand,eye,and walk is normal,,but i'm afraid that is to come

  • @IAMGiftbearer
    @IAMGiftbearer 2 роки тому

    I'm assuming this is the human version this refers to, as an article about the dog version says it's autosomal recessive rather than autosomal dominant.

    • @vananhtran4994
      @vananhtran4994 11 місяців тому

      It is different, if friedreich’s ataxia or ataxia telangiectasia they are recessive

  • @omidkamjoo7939
    @omidkamjoo7939 2 роки тому

    سلام درمانش تو آریکا آمده؟

  • @adityabhinde4699
    @adityabhinde4699 3 дні тому

    Sir mere bete ko bhi spinocerebellar ataxy 1 phethogenic he

  • @sharmamathi4103
    @sharmamathi4103 3 роки тому +1

    I have sca 1 table rate so high so please any one help any foundation is there please tell

    • @Decodecyber_help
      @Decodecyber_help 3 роки тому

      Search for Dr nafuar on UA-cam

    • @faisaltasiu5421
      @faisaltasiu5421 3 роки тому

      Thanks to dr nafuar on UA-cam for permanently curing me using his herbal medicine now I’m perfectly fine and ataxia free

  • @Anuanu-uc5bq
    @Anuanu-uc5bq 11 місяців тому

    0:20,3:02,4:15

  • @scakardesler
    @scakardesler 3 роки тому +1

    Merhabalar, sca hastaliginin farkındalığı yolunda bize destek olabilir misiniz

  • @j-hopesstrawberriesfanfics992
    @j-hopesstrawberriesfanfics992 3 роки тому

    I hace SCA type 27, I cant even write a word sometimes and say a word

    • @Decodecyber_help
      @Decodecyber_help 3 роки тому

      Thanks to Dr nafuar he cured me from ataxia

    • @faisaltasiu5421
      @faisaltasiu5421 3 роки тому

      Special thanks to dr nafuar for permanently curing me of my ataxia using his herbal medicine now I’m feeling better and ataxia free thanks dr nafuar

  • @fashionmixtapes
    @fashionmixtapes 2 роки тому

    IVIG

  • @soldierofgod349
    @soldierofgod349 4 роки тому +2

    I’ve got this It’s absolutely horrible

    • @sv4tech792
      @sv4tech792 4 роки тому

      @@annthompson3137 one of my family.5 person affected..One of them passed away before 1week
      No medicine in india

    • @sv4tech792
      @sv4tech792 4 роки тому +1

      @@annthompson3137 sure.. Please share

    • @sv4tech792
      @sv4tech792 4 роки тому

      @@annthompson3137 which country u r from?

    • @sv4tech792
      @sv4tech792 4 роки тому

      @@annthompson3137 INDIA

    • @sv4tech792
      @sv4tech792 4 роки тому

      Is there any medicine or like therapy treatment

  • @NERVESMEDICINE616
    @NERVESMEDICINE616 4 роки тому +1

    👍

  • @fousadkanjippura447
    @fousadkanjippura447 3 роки тому

    എനിക്കും ഈ പ്രോബ്ലം ഉണ്ട്
    Treatment പറയുമോ

  • @notyouraveragecentrist4536
    @notyouraveragecentrist4536 2 роки тому

    We should develop prenatal testing for that so we can prevent those things from being born