Teaching cardiology better than any cardiologist we've seen in med school... thank you for making this available to train doctors and healthcare workers around the world! This channel is a gift to humanity!
I'm a very busy family medicine doctor with 28 years of ER and urgent care as well as hospitalist service experience and I have to say these Ninja Nerd videos are the BEST teaching videos I have seen. Lot's of deep dive detail that I wish I would have had in medical school, but the internet was just getting up and started in the early 90's when I was in training and residency. This would have been fantastic to have "back in the day." GREAT stuff here.
In the name of all the romanian medical students i would like to thank you. We have our residency exam in two weeks and this topic is a very big one in our bibliography and a very troublesome one, may I add. This will come in real handy. Thank you!
Not only students, but also pensioners when we are lonely and have nobody to talk to we listen your lectures to know our illnesses to live longer. 60 yo. Thank you that you are. 💐
I had heart failure with a LVEF below 40%. With Entresto and after a year on it and then discontinuing it, my LVEF was 65%. I've been without the drug for more than a year now and my heart is still perfect. In other words, I've been cured of heart failure thanks to Entresto!
Entresto has improved my EF from 25% -45% in 6 months and i have been wondering if I will need to keep taking the med if EF returns to normal range - my cardiologist says that’s close enough to normal but I’m hoping fr further improvements at the 12 month marker as the study results showed. Good to know what’s possible thanks👍👍👍
This dude have taught me not only medicine but also, what commitment actually means. Huge and massive respect buddy for your time and commendable efforts.🙌 Can't imagine how you gather all the information from various literatures and put them altogether within just a week that too in a 3-hour video ✌ Tons of love and appreciation to you and your team 🙌❤ please keep doing 🌠
From someone who found Dr Ninja looking for just this subject, your other video on this topic helped me know that my husband was on the correct drugs for his possible class 2 of heart failure. (He had a quintuple bi -pass just just 3 1/2 years before.) Which then lead to the three scheduled tests US of abdomen, CT, and an Echo! All waiting to take place, to help find the cause of his now (some 70 lbs )of Water weight gain in 4 weeks time!
I AM HABTAMU TEKALIGN FROM ETHIOPIA I AM CLINICAL PHARMACY STUDENT SINCE FIRST YEAR I AM USING YOUR TUTORIAL VIDEO ITS SO SUPPORTIVE NOW I AM ONE OF TOP SCORER THANK YOU BIG BRO NINJA
This guy does such an AMAZING job of explaining these concepts!! I hope he continues to teach bc many are not able to explain complex mechanisms this well, making it easy to hold our attention in my opinion!! His pace of speaking is just perfect!, easy to keep up with & definitely not dull & boring!! Thank you!!
You are the best person ever who can discuss anything you’re asked to do. You have a unique way of explaining everything so we can understand. Pls keep doing your education videos. Plenty of medical staffs are benefiting out of them like me. I love you!!!
1:04:15 Actually, the 2022 AHA/ACC Guideline on heart failure now suggests that ARNi are now first-line RASi in HFrEF, *ahead* of ACEIs and ARBs. ARNi first, then ACEI if ARNi can't be tolerated (or afforded), then ARB if ACEI can't be tolerated (e.g., angioedema, bradykinin cough). This recommendation is different than what you say in here regarding order of priority. Nitpicking aside, this is a *fabulous* teaching video.
hey, I'm not a medical student or anything but I love genuinely learning about how the body functions, thank you so much for making this knowledge available for free, actually would cost thousands of dollars of books to learn this stuff otherwise. actual chad
I am a 74 year old male with a pacemaker and use anti hypertension drugs. I did not want to use metaprolol because I am still a racing cyclist and I want a high cardiac output for that reason. You told that metaprolol initially lowers the heartrate (and therfore the Cardiac output) but after some time it even increases the cardiac output. That is nice to hear and I wished I knew that earlier. Thank you! Today I use Perindopril, Nifedipine, Xarelto and Jardiance and I feel fine.
My exam is on the 5th of January And I'm so thankful cos I'm studying pharma from your wonderful channel It's so entertaining to learn it from you zach Thank you so much for your magnificent effort 💗
Thanks you Dr ninjanerd you are best lectural for medical department, we hope next video for pharmacology will be Diabetes mellitus drugs and their classification in best teaching and memory way
I'm male, 78 (almost) and I was diagnosed with heart failure 4 months ago with an ejection fraction of 25% to 35%. I'm now taking a cocktail of drugs: Entresto, Apixaban, Rosuvastatin, Furosemide, Bisoprolol, Eplerenone, Dapagliflozin and Aspirin. 11 years ago I had a triple CABG and made a full recovery. Three months after the operation I had a follow-up with a cardiologist and had an echocardiogram. The result of that, however, was an EF of 60%, no noticeable valve disease and the heart was pronounced good. In the intervening years I lost a lot of weight by counting calories and I modified my diet considerably with grains, wholemeal bread, lots of fish, including oily fish. What I want to know is how the EF can sink from 60% to as low as 25% in 11 years.
You may be in residency or fellowship training now as I have noticed the decreased number of recent videos BUT I PRAY MY FRIEND that you are working toward a specialty where you will be able to teach at least a large percentage of the time in a medical school, and a medical school that will allow you to continue this work with these videos and on your website because YOU HAVE A SPECIAL GIFT and are helping so many health care professionals and others be better practitioners and better people. YOU HAVE HELPED RESTORE MY LOVE FOR MEDICINE WHICH I HAD GOTTEN AWAY FROM. GOD BLESS YOU MY FRIEND. I know you would be a phenomenonal researcher and clinical practitionerand I PRAY ( selfishly I readily admit 😂) THAT YOU LEAN TOWARD TEACHING ( along w some clinical care to keep you FRESH, of course )
I'm watching again. The signals from the heart to the medulla obligata is by the IXth (9th) cranial nerve, or the glossopharangeal nerve. The Xth (10th) is the vagus never. I had to look it up to be sure, as it had been a while, but hopefully, that's helpful for someone. The carotid sinus baroreceptors are innervated by the carotid sinus nerve branch of the glossopharyngeal nerve. Their stimulation results in heart rate reduction mediated by the vagus nerve. Thanks for your lectures!
I just found you. You're an excellent instructor/professor. I'm having to take this in a bit at a time, but excellent teaching, excellent content, and to the point. I hope and pray that you are teaching as many students as possible, as we need tons of clones of you who can learn, and then they can teach others as well, and so on. You have a great voice, you cover the subject matter in an organized manner, you are clear, you have drawings and printing that is great and readable. Can you do a video on Alpha-1 antitrypsin deficiency MZ phenotype, and treatments for lung, liver and eye inflammation, drugs to avoid (such as Tamiflu, NSAIDS, Tylenol, etc.), risks for heart, lung, liver, kidneys, brain, retinas (especially in children), etc.? It seems MZs are more at risk for both lung and liver problems, as well as other problems that have very little research, it seems. This would be greatly appreciated, both from a personal and professional standpoint. Thanks for at least considering this. I agree that Ivabrdine is a strange bird... Wouldn't the ion transfer create a delay in and/or prolongation of ST waves? And all that entails? (Early repolarization, aneurysms, pancreatitis, etc.)??? I'm asking, as it seems that could be a problem, and without other meds, a possible increase in stroke risks??? I can see why they'd need to ideally be maxed on a beta blocker when using Ivabradine. And a
Another video on your channel explaining CHF was so clear, informative & helpful - so, thank you..Got anything on APS, Auroimmunity diseases? If one wants to empty a room of medical folks just ask questions about APS , lol (and yes, sometimes that is desirable). Can be difficult to get & understand enough information to make decisions regarding one's health- very frustrating.
can you please continue on the cell biology videos, for example, the techniques for monitoring and manipulating cells and genetic material? you are the best teacher ever:)
In Australia we've added SGLT2 inhibitors like dapagliflozin to our first line therapy along with the beta blockers and ARNI + valsartan. It's unknown why but seems to be cardioprotective and improve outcomes, likely due to the diuretic effect.
It is interesting you mentioned the Entresto is an alternative because I was diagnosed with CHF with 35% EF and was started on Entresto and BisOPROLOL. I was told that I would be on four type of medication as my first line which is the Entresto, BisOPROLOL, Spironolactone and Empaglifozin. Is this perhaps the new standard for CHF first line?
Dude I have heart failure and you just answered sooooo many questions for me with this one. I was in the air about all of this and what each drug does before your picture I understood absoloutely everything and I’m not a doctor Amazing explanation
Very informative. I'm trying to treat my 81 year old mother and understand Bisoprosol etc :) She always has 'perfect' blood pressure and heart function (according to a dozen different cardiac tests (I am getting a BNP test next week as 'definitive' test for HF as she is physically weak) but is still prescribed Bisoprosol? Q: Is Bisoprosol necessary in cases where the heart/vascular sys appears to be functioning well? To help me see how using Beta-blockers may help, can you point me to study(s) that show beta blockers decrease mortality long term HF patients - as oppose to in theory - so I can see it in action? Thanks. UPDATE: "longer diastolic filling process" - I watched again helps heart get more oxygen - but again Bisoprosol when BP and HR and O2 all good? Q2: So the heart muscle/function CAN heal in some instances? (I read and saw some docs saying the heart is an organ where damaged tissue does not regenerate - perhaps you mean with BB's it can start to work more efficiently again and in that sense 'heal'? :)
Teaching cardiology better than any cardiologist we've seen in med school... thank you for making this available to train doctors and healthcare workers around the world! This channel is a gift to humanity!
Real life and models are very different
for sure
couldn’t agree more 💯
I'm a very busy family medicine doctor with 28 years of ER and urgent care as well as hospitalist service experience and I have to say these Ninja Nerd videos are the BEST teaching videos I have seen. Lot's of deep dive detail that I wish I would have had in medical school, but the internet was just getting up and started in the early 90's when I was in training and residency. This would have been fantastic to have "back in the day." GREAT stuff here.
I'm dealing with stage 3 heart failure and taking several meds...I learned enough to talk to my doctor thank you❤
On behalf of the entire medical students in Sierra Leone, we want to thank you for all you have done for us…Thank you Prof Ninja Nerd ❤
Are there many bengali people in your country??just curious
In the name of all the romanian medical students i would like to thank you. We have our residency exam in two weeks and this topic is a very big one in our bibliography and a very troublesome one, may I add. This will come in real handy. Thank you!
Indians too
Scottish too❣
Iraqi too
serbian too
Greek too
Not only students, but also pensioners when we are lonely and have nobody to talk to we listen your lectures to know our illnesses to live longer. 60 yo. Thank you that you are. 💐
😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊
❤
❤😊
I'm trying to comment on all the videos I watch as I'm going through PA school. This man is an amazing instructor and gifted speaker.
I had heart failure with a LVEF below 40%. With Entresto and after a year on it and then discontinuing it, my LVEF was 65%. I've been without the drug for more than a year now and my heart is still perfect. In other words, I've been cured of heart failure thanks to Entresto!
Entresto has improved my EF from 25% -45% in 6 months and i have been wondering if I will need to keep taking the med if EF returns to normal range - my cardiologist says that’s close enough to normal but I’m hoping fr further improvements at the 12 month marker as the study results showed. Good to know what’s possible thanks👍👍👍
This dude have taught me not only medicine but also, what commitment actually means. Huge and massive respect buddy for your time and commendable efforts.🙌 Can't imagine how you gather all the information from various literatures and put them altogether within just a week that too in a 3-hour video ✌ Tons of love and appreciation to you and your team 🙌❤ please keep doing 🌠
I can't listen to any other person having 3 hours of lectures but it's only youuuuuu to whom I can listen 😭
From someone who found Dr Ninja
looking for just this subject, your other video on this topic helped me know that my husband was on the correct drugs for his possible class 2 of heart failure.
(He had a quintuple bi -pass just just 3 1/2 years before.)
Which then lead to the three scheduled tests US of abdomen, CT, and an Echo!
All waiting to take place, to help find the cause of his now (some 70 lbs )of Water weight gain in 4 weeks time!
Medical lectures owe you a lot..You are a boss man..
I AM HABTAMU TEKALIGN FROM ETHIOPIA I AM CLINICAL PHARMACY STUDENT SINCE FIRST YEAR I AM USING YOUR TUTORIAL VIDEO ITS SO SUPPORTIVE NOW I AM ONE OF TOP SCORER THANK YOU BIG BRO NINJA
This guy does such an AMAZING job of explaining these concepts!! I hope he continues to teach bc many are not able to explain complex mechanisms this well, making it easy to hold our attention in my opinion!! His pace of speaking is just perfect!, easy to keep up with & definitely not dull & boring!! Thank you!!
Your videos are so good that I always hit the like before watching. Congratulations on your dedication and knowledge!
Thanks for you bro from my heart, your the the best lecturer in the world. Keep going
Greating from sudan 🇸🇩🇸🇩
You are the best person ever who can discuss anything you’re asked to do. You have a unique way of explaining everything so we can understand. Pls keep doing your education videos. Plenty of medical staffs are benefiting out of them like me. I love you!!!
you, your team, your spouse, your dog, your mailman and your mama....IS THE MAN. Thank You for helping out the little guy !!!!!
I am not even a physian but in another medical field and enjoy the courses.
EMT-b and nursing student here. Thank you. I believe I have a better and more in depth understanding of the material than any of my peers now.
1:04:15 Actually, the 2022 AHA/ACC Guideline on heart failure now suggests that ARNi are now first-line RASi in HFrEF, *ahead* of ACEIs and ARBs. ARNi first, then ACEI if ARNi can't be tolerated (or afforded), then ARB if ACEI can't be tolerated (e.g., angioedema, bradykinin cough). This recommendation is different than what you say in here regarding order of priority.
Nitpicking aside, this is a *fabulous* teaching video.
Ah yes coz that was what I was given which is the Entresto when I was diagnosed with CHF last year with reduced EF.
hey, I'm not a medical student or anything but I love genuinely learning about how the body functions, thank you so much for making this knowledge available for free, actually would cost thousands of dollars of books to learn this stuff otherwise. actual chad
This is one of the best educative sites ever visited
I wish this was published prior to my ICU rotation in PA school, but it's still a great review now. Thanks!
Teaching like this is a GIFT that this superstar shares with all of us! 👍👍👍
I am a 74 year old male with a pacemaker and use anti hypertension drugs. I did not want to use metaprolol because I am still a racing cyclist and I want a high cardiac output for that reason.
You told that metaprolol initially lowers the heartrate (and therfore the Cardiac output) but after some time it even increases the cardiac output. That is nice to hear and I wished I knew that earlier. Thank you! Today I use Perindopril, Nifedipine, Xarelto and Jardiance and I feel fine.
My exam is on the 5th of January
And I'm so thankful cos I'm studying pharma from your wonderful channel
It's so entertaining to learn it from you zach
Thank you so much for your magnificent effort 💗
You just dymystified heart failure with low EF. Thank you so very much for this presentation
Thank you so much, you are just the best of all.
I Pray for more wisdom and long life so that you keep of helping even the new generation to come 🙏🏾🙏🏾
Thanks you Dr ninjanerd you are best lectural for medical department, we hope next video for pharmacology will be Diabetes mellitus drugs and their classification in best teaching and memory way
I enjoy all your videos I think I'm ready for medical school now after watching your videos and the way you teach the lecture
Thank you very much for your time and effort producing this learning material. It will help me in my practice and benefit hundreds of my patients.
Due respect 🙏 .....!!bow down to u dr Zack🙌🙌🙌🙌
Thank you so much for educating patients with their diseases CHF.
I'm male, 78 (almost) and I was diagnosed with heart failure 4 months ago with an ejection fraction of 25% to 35%. I'm now taking a cocktail of drugs: Entresto, Apixaban, Rosuvastatin, Furosemide, Bisoprolol, Eplerenone, Dapagliflozin and Aspirin. 11 years ago I had a triple CABG and made a full recovery. Three months after the operation I had a follow-up with a cardiologist and had an echocardiogram. The result of that, however, was an EF of 60%, no noticeable valve disease and the heart was pronounced good. In the intervening years I lost a lot of weight by counting calories and I modified my diet considerably with grains, wholemeal bread, lots of fish, including oily fish. What I want to know is how the EF can sink from 60% to as low as 25% in 11 years.
wow. i d think i would need my book after this. thankyou for helping me engrave this concept in m mind
Zach Murphy the great 🖤🇸🇸
This is so awesome. I have a child with chd and its sooooooooo helpful to hear what these meds are doing
You may be in residency or fellowship training now as I have noticed the decreased number of recent videos BUT I PRAY MY FRIEND that you are working toward a specialty where you will be able to teach at least a large percentage of the time in a medical school, and a medical school that will allow you to continue this work with these videos and on your website because YOU HAVE A SPECIAL GIFT and are helping so many health care professionals and others be better practitioners and better people. YOU HAVE HELPED RESTORE MY LOVE FOR MEDICINE WHICH I HAD GOTTEN AWAY FROM. GOD BLESS YOU MY FRIEND. I know you would be a phenomenonal researcher and clinical practitionerand I PRAY ( selfishly I readily admit 😂) THAT YOU LEAN TOWARD TEACHING ( along w some clinical care to keep you FRESH, of course )
I’m a med tech entrepreneur and you are the reason my company exists ❤
LOVE his energy for teaching!!!
Just in time!
Thank you
I'm watching again. The signals from the heart to the medulla obligata is by the IXth (9th) cranial nerve, or the glossopharangeal nerve. The Xth (10th) is the vagus never.
I had to look it up to be sure, as it had been a while, but hopefully, that's helpful for someone.
The carotid sinus baroreceptors are innervated by the carotid sinus nerve branch of the glossopharyngeal nerve. Their stimulation results in heart rate reduction mediated by the vagus nerve.
Thanks for your lectures!
For those who are interested in Pharmacology strongly advised I strongly recommend this channel to be followed
I just found you. You're an excellent instructor/professor. I'm having to take this in a bit at a time, but excellent teaching, excellent content, and to the point.
I hope and pray that you are teaching as many students as possible, as we need tons of clones of you who can learn, and then they can teach others as well, and so on.
You have a great voice, you cover the subject matter in an organized manner, you are clear, you have drawings and printing that is great and readable.
Can you do a video on Alpha-1 antitrypsin deficiency MZ phenotype, and treatments for lung, liver and eye inflammation, drugs to avoid (such as Tamiflu, NSAIDS, Tylenol, etc.), risks for heart, lung, liver, kidneys, brain, retinas (especially in children), etc.?
It seems MZs are more at risk for both lung and liver problems, as well as other problems that have very little research, it seems.
This would be greatly appreciated, both from a personal and professional standpoint. Thanks for at least considering this.
I agree that Ivabrdine is a strange bird... Wouldn't the ion transfer create a delay in and/or prolongation of ST waves? And all that entails? (Early repolarization, aneurysms, pancreatitis, etc.)???
I'm asking, as it seems that could be a problem, and without other meds, a possible increase in stroke risks???
I can see why they'd need to ideally be maxed on a beta blocker when using Ivabradine. And a
Thank you for this awesome lecture. Your knowledge and commitment is remarkable.
Zach is a such amazing human being- lovely and talented. ❤️
Great content as always. Easy to understand, easy to revise and learn from. Your videos are a lifeline!
Another video on your channel explaining CHF was so clear, informative & helpful - so, thank you..Got anything on APS, Auroimmunity diseases? If one wants to empty a room of medical folks just ask questions about APS , lol (and yes, sometimes that is desirable). Can be difficult to get & understand enough information to make decisions regarding one's health- very frustrating.
When are you coming at India sir???
Thanks man , you are a great help to medical students
Bro...I have no words for these masterpiece.. Greetings fm 🇮🇳
Can't imagine studying medicine without your videos! :')❤❤❤
God bless you
thanks a bunch
a lot of info presented very well.
great lecture as always. i wish you'd add the sglt2-i and its role in HF to this lecture per the 2022 gdmt. Thank you so much!
Thank you Ninja Nerd very much!
You are a blessing🤌🤌🤌 thank you so much for all these lectures and efforts you make
Professor-
Please do a similar exposé on how SGLT2 inhibitors work for non-diabetic heart failure patients with low EF (
Thanks Dr ...from Yemen
Thank you for this detailed explanation. It is truly a fantastic video.
can you please continue on the cell biology videos, for example, the techniques for monitoring and manipulating cells and genetic material? you are the best teacher ever:)
Thank you dear!
amazing stuff as usual
In Australia we've added SGLT2 inhibitors like dapagliflozin to our first line therapy along with the beta blockers and ARNI + valsartan. It's unknown why but seems to be cardioprotective and improve outcomes, likely due to the diuretic effect.
We also learned about the role of SGLT2-i in my PA program in the US. Seems especially useful given the frequent comorbidity of HF and DM.
In NHS too we add DAPA 10 along with others
Thank you so much for saving my semester! ❤
Thank you Dr ninja
thank u this is the best lection
We want some cell Bio Lectures in the upcoming days :)
Greatest man for ever.
You deserve to be the hero who save medical students ❤
Could you do a video on the LVAD and RVAD?
Your video to this topic is impressive, Brilliant, thank you
Love love love your videos. Please keep posting on more and more new topics
ACE-I and ARBs are not first line for HFpEF. The lecture though is quite good. Also SGLT-2 inh. are first line for HFrEF and HFpEF
thank you bro like really we are all grateful you exist ,
Best 3 hours ive ever invested in
🫵 You, Professor Zach Murphy 🧠 gave a 2:52:11 on drugs 💊🧪💉for heart 🫀failure.
W. O. W. Almost 3 hours!! I … had to take breaks🥵🥵🥵 THANKS 🥰🥰🥰
Thank you so much ❤
It is interesting you mentioned the Entresto is an alternative because I was diagnosed with CHF with 35% EF and was started on Entresto and BisOPROLOL. I was told that I would be on four type of medication as my first line which is the Entresto, BisOPROLOL, Spironolactone and Empaglifozin. Is this perhaps the new standard for CHF first line?
Im so grateful for you prof
Thank u very much
The best
Half of heart failure patients have heart failure with preserved ejection fraction but you didn't address this and what medications to take???
Thank you for your lectures
That " Bro please , stop filling me up , I've got too much in my ventricles " caught me off guard.
Hey Zach, how about the antidepressant and antipsychotic drugs vids?? Huhu
love u ninja nerd
I am thankful you to for your interesting teaching methods.great work. I m interested very.
Dude I have heart failure and you just answered sooooo many questions for me with this one.
I was in the air about all of this and what each drug does before your picture
I understood absoloutely everything and I’m not a doctor
Amazing explanation
Leaving a comment 😬
Cool!!!
Please make a video on antiarrhythmic drugs
❤❤❤thank you for sharing 😊
Very informative. I'm trying to treat my 81 year old mother and understand Bisoprosol etc :) She always has 'perfect' blood pressure and heart function (according to a dozen different cardiac tests (I am getting a BNP test next week as 'definitive' test for HF as she is physically weak) but is still prescribed Bisoprosol? Q: Is Bisoprosol necessary in cases where the heart/vascular sys appears to be functioning well? To help me see how using Beta-blockers may help, can you point me to study(s) that show beta blockers decrease mortality long term HF patients - as oppose to in theory - so I can see it in action? Thanks. UPDATE: "longer diastolic filling process" - I watched again helps heart get more oxygen - but again Bisoprosol when BP and HR and O2 all good? Q2: So the heart muscle/function CAN heal in some instances? (I read and saw some docs saying the heart is an organ where damaged tissue does not regenerate - perhaps you mean with BB's it can start to work more efficiently again and in that sense 'heal'? :)
Thanks ❤
Not all heroes wear capes!❤
Dude you are a blessing!
In time 🤗✌🏻