Opioid Drugs, Part 1: Mechanism of Action

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  • Опубліковано 21 лис 2024

КОМЕНТАРІ • 284

  • @redflare7051
    @redflare7051 6 років тому +48

    This is just the right amount of complexity I'm looking for in an educational video.
    Not too simple that I learn too little.
    And not too hard that it just becomes academical and too technical.
    I really like your videos , keep up the great work.

  • @zakariyaferouz2023
    @zakariyaferouz2023 Рік тому +1

    Pharmacy student here, learning about opioids and this video is much better than what my professor taught in class, hits all the points he also taught but it a much more condensed but informative way. Great video.

  • @ATA-wi2lh
    @ATA-wi2lh 4 роки тому +35

    Omg this is so good. Allows us to visualize what’s going on rather than just memorizing text

  • @miless.-d.782
    @miless.-d.782 5 місяців тому +2

    The way this Video explained this topic is insane. The graphical demonstration is just awsome

  • @nandygumma8707
    @nandygumma8707 4 роки тому +8

    you have taken the whole topic piece by piece and explained it in a microscopic level. thank you!

  • @TheGlamourNazi
    @TheGlamourNazi 6 років тому +196

    This video blows my mind. Just seeing how complex one neuron is blows my mind when I realize how many of those little dudes do all that stuff when I stub my toe

    • @gerardovega7983
      @gerardovega7983 4 роки тому +1

      I’m high af and this is tripping me out lol 😆

    • @complicational
      @complicational 3 роки тому +2

      @TheGlamourNazi if you read your comment again, theres only one conclusion i.e. Intelligent Design

    • @gensaikawakami341
      @gensaikawakami341 3 роки тому

      @@complicational no way bro, I just can't accept something so nonscientific (not a real word).
      It's way more believable that all these systematic organic structures made themselves over billions of years and in direct conflict with the most basic concepts of classic physics.
      But really I'll believe anything so long as I don't have to be held accountable for my decisions.

    • @jukodebu
      @jukodebu 3 роки тому

      @@complicational or millions of years of trial and error

    • @mariooldani9545
      @mariooldani9545 2 роки тому

      No.

  • @huda6661
    @huda6661 5 років тому +39

    This is amazing. You saved me, I really needed this to study for my medicinal chemistry exam 💙

  • @ПетърЖотев-п4р
    @ПетърЖотев-п4р 6 років тому +12

    WOOOOOOOOOOOOOOOOOOW!!!! I HAD NO IDEA THAT OUR CELLS AND NEURONS CAN BE SO COMPLICATED! THANKS VERY MUCH!!!! YOU DESERVE BILLIONS OF SUBS!

  • @karrle9008
    @karrle9008 6 років тому +25

    You did really well describing those complex mechanism. I'm excited to see part 2

  • @amaris3848
    @amaris3848 3 роки тому

    This is the best video I've ever found on opioid drugs. Thank you for helping me through nursing! This is amazing!

  • @gooseghazi
    @gooseghazi 6 років тому +1

    Better than ANY text, pain board review book or course I’ve taken as a pain doc!! Outstanding work!! Superb explanation!!!

  • @scifiaudious2
    @scifiaudious2 5 років тому +12

    best presentation on this I have seen

  • @GSCt1000
    @GSCt1000 4 роки тому

    I've been looking for a detailed information on this subject... and not the mainstream simplification.
    Thanks for the info.

  • @wiki5566
    @wiki5566 3 місяці тому

    Why you stopped upload more videos? Teachers like you needed badly. I wish your perfect health and long life. Please upload more.

  • @meleciamapuanadefreitas7606
    @meleciamapuanadefreitas7606 3 роки тому

    It sounded so clear, to the point and visually easy to understand. Great job ! Best video on you tube for this topic!!!

  • @homemadelemonade976
    @homemadelemonade976 6 років тому +17

    An amazing video. Complicated enough to be interesting, but not too simple to be lacking. Awesome

  • @xXMaster97Xx
    @xXMaster97Xx 4 роки тому

    This is the best video about this topic that I came across. I hardly comment on videos but this was amazing.

  • @signaturemove1976
    @signaturemove1976 2 роки тому

    before watching this video I was confused a lot about opiod , now I got the point, thank you sir
    Expecting more videos from you

  • @MiniMackeroni
    @MiniMackeroni 6 років тому +9

    This is a fantastic channel. It's always so interesting to learn both how redundant and convoluted processes inside our bodies are. So many twists and turns to activate a single type of receptor or inhibitor.

  • @cameronnorby3905
    @cameronnorby3905 6 років тому +20

    Just found your channel and I'm already impressed! I was wondering, do you think you would be able to do a video explaining depression and the medicine behind antidepressants some time in the future?

  • @yduchoa7276
    @yduchoa7276 Рік тому

    The most effective explanation I have ever seen about Opioid. Thank you so much for your videos. Everything is actually clear and easy to understand. It helps me too much in my study. Love and appreciate your work ❤❤❤

  • @SirApexTV-official
    @SirApexTV-official 2 роки тому +1

    Spot on ! Everything you said was correct, you should be a med teacher like my self. I work at cambridge university England! Keep up the outstanding work ♡

  • @DaLokNessMonster
    @DaLokNessMonster 6 років тому +1

    EXACTLY what i need! This has simplified things a lot, thank you I feel way more confident for my presentation now!

  • @mari-lay833
    @mari-lay833 3 роки тому

    Subscribed! You're a lifesaver. Please come back and continue making videos.

  • @marishtadon2538
    @marishtadon2538 Рік тому +1

    This is a really comprehensive video! I could not understand my lecture for it being too complex and I am glad I stumbled upon your video. The animation helps in getting a clearer picture on the mechanism of opioids at micro level. On top of that, the simplicity in the way you explain makes everything much easier. Thank you so much 🙌💫 You just earned a new subscriber and you deserve wayyy more 💪

  • @Atropin4ik
    @Atropin4ik 6 років тому +2

    O, man!! Such a great video!! Was looking for some source to refresh my knowledge, but most of youtube videos are so superficial, or opposite to detailed in a harm way, or just full of trash talking. Your submission of the information is amazing! Thank you so much.

  • @danielmcsween9054
    @danielmcsween9054 6 років тому +36

    First: Great video!
    Second: Can you do a series about all parts of the immune system?

    • @Medicurio
      @Medicurio  6 років тому +15

      I hope to address more aspects of the immune system by discussing diseases that arise from dysfunctions of the immune system. You can check out my celiac disease video for mhc presentation/CTLs and multiple sclerosis for autoimmunity (and hopefully future videos)

  • @hiepnguyenhoang832
    @hiepnguyenhoang832 Рік тому

    OMG this is so well made, well researched! These are kinds of video I want to see! This is the epitome of educational video, not the abounding dull videos that basically repeat "heroin relieves pain, but heroin is bad" for the entire duration.

  • @howtomedicate
    @howtomedicate 5 років тому +3

    Great video! You explained it very clearly!
    I just started my own medical youtube channel, and I also made a video on Morphine.
    However I still find it hard to find the balance between informational content and a fun way to explain it.
    You do this in a very natural way, which inspired me to make my videos more visual.
    Keep it up!

  • @ismailelghuwael6859
    @ismailelghuwael6859 6 років тому +2

    Very interesting. needs to pay attention and listen step by step

  • @BasicallySteve23
    @BasicallySteve23 6 років тому +2

    Another excellent video! Your channel is severely underrated. Well done!

  • @cdjwright
    @cdjwright 6 років тому +3

    What a perfect birthday present to me! Thanks for the video!

  • @hattivattimymmeli2121
    @hattivattimymmeli2121 6 років тому

    Amazing video with great quality! i dont understand why this channel doesnt have millions of views,,,,,,

  • @mill336
    @mill336 3 роки тому

    I can't stress how good this video is, so good. Thanks!

  • @jackierubinstein548
    @jackierubinstein548 2 роки тому

    this is the best explanation I've ever seen

  • @2tiggsU
    @2tiggsU 3 роки тому

    Excellent video! Well done, very simplified and easy to follow...

  • @Omargharbi5038
    @Omargharbi5038 6 місяців тому

    This is the best ed video that i watched in my life ⭐️⭐️⭐️⭐️

  • @account-fm2li
    @account-fm2li 5 років тому +1

    MIND BLOWING! This video explains its clearly form the endogenous mechanism of norciceptive and antinorciceptive pathways and also the MOA of opiod 🤯🤯🤯🤯🤯 thanks

  • @TheBennychin
    @TheBennychin 4 роки тому +14

    This made my brain hurt. I need some pain relief. Time to get some opioids!

  • @pranavireddy309
    @pranavireddy309 2 роки тому

    wow........this is the most perfect video that i hav ever seen
    it cleared all my doubts in various topics and subjects
    thank you so much sir❤❤

  • @whatsleft100
    @whatsleft100 4 роки тому

    The Graphics in this video and the colour choices are superb .
    Great explanation.

  • @kooshasaami3027
    @kooshasaami3027 4 роки тому

    far better than university pharmacology lecture !! thanks a lot !

  • @amiramnd8964
    @amiramnd8964 4 роки тому

    This presentation is amazingly simplified !! You just saved my year, thank you so much !!

  • @Delzak1
    @Delzak1 6 років тому +5

    Fantastic video as always. Super glad to have found this channel!

  • @dustinkenyon5650
    @dustinkenyon5650 4 роки тому +5

    How can I "superlike" this?

  • @theresamartinelli8844
    @theresamartinelli8844 8 місяців тому

    Great video and highly understandable for the common person to learn thank you.

  • @MariaM-bv5ew
    @MariaM-bv5ew 6 років тому +1

    I got an exam at Pharmacology including opioid drugs and this video helped me a lot to understand the mechanism of action. Thanks, you're doing a great job!

  • @BeardedGoats
    @BeardedGoats 5 років тому

    This video is nothing short of amazing, especially for visual learners like me. Thank you!

  • @semiconductorsinarabic4090
    @semiconductorsinarabic4090 5 років тому

    I found this channel yesterday and i am totally in love with it! I love you man and your effort in making these videos. Please do not stop making these kind of videos and i hope you sponsor your channel to become more popular on UA-cam! ❤️❤️❤️❤️❤️❤️❤️❤️❤️

  • @lamperouge459
    @lamperouge459 6 років тому +2

    This video is perfect, please keep enlighting us with your knowledge!

  • @InderSingh-kr2bl
    @InderSingh-kr2bl 6 років тому +4

    I found this channel because of tier zoo and I love how thoroughly explained each topic is. Would be cool if you could cover some genetic / inherited diseases or even something like patau syndrome or cyclopia

  • @YashPatel-yt6ql
    @YashPatel-yt6ql 2 роки тому

    Thank you for making simplified

  • @swatiangdi780
    @swatiangdi780 4 роки тому

    Very Informative video. Its been very long i m in search of such kind of videos. Thankyou so much for detailed explaination.👍

  • @aninalee1726
    @aninalee1726 4 роки тому

    So thrilled to have found this channel. Great stuff!

  • @akshatsahai3551
    @akshatsahai3551 6 років тому +2

    Brilliant ! Please continue making such videos !!
    Thanks !

  • @rockyboy220
    @rockyboy220 4 роки тому

    Good lecture...structured and clearly delivered

  • @sorwis
    @sorwis 4 роки тому

    Excellent high level explanation of the mechanisms behind opioids. These videos make it easier to delve deeper into the subjects.

  • @misbahmughal7577
    @misbahmughal7577 3 роки тому

    Wow such a crystal clear concept based video i have never seen before❤️❤️i m your big fan now😍😍

  • @froggoesjump2185
    @froggoesjump2185 3 роки тому

    Grate talk but when are you going to cure withdraw pain, because i'm tempted to do it myself soon.

  • @bellyvelly
    @bellyvelly 7 місяців тому

    that's literally what I've been looking for thank u ❤

  • @morejames277
    @morejames277 11 місяців тому

    Very detailed and informative; thanks so much.

  • @h.q.1736
    @h.q.1736 3 роки тому

    The best explanation ever ..thank you so much

  • @skitzosenor6858
    @skitzosenor6858 6 років тому +1

    This is a video I've been wanting to see for a while, can't wait for part 2! Would you consider making one on hair loss as well? I've yet to see something on a molecular level like this and it's another video I've been wanting to see.

  • @mjmo473
    @mjmo473 3 роки тому

    This is a great video that's simplifies complex mechanisms. I am a developing educational content for RNs taking their Critical Care course. May I use this video for my module on pain strategies?

  • @Meeoows1
    @Meeoows1 4 роки тому

    Please make lectures on GIT pharmacology and cancer chemotherapy

  • @wahabkhanz36
    @wahabkhanz36 10 місяців тому

    This video is amazing and very helpful thank you so much for making such kind of helpful and easy videos.❤

  • @rizkitriono
    @rizkitriono 6 років тому

    Such a good video! Thank you so much! Where is the part 2 ??

    • @Medicurio
      @Medicurio  6 років тому

      Will be done in a few weeks!

  • @doctorkokus
    @doctorkokus 4 роки тому +2

    I’m writing a fairly large assignemnt at the end of term, and this video helped me chose to write about pain physiology. Thank!

  • @riyashinde805
    @riyashinde805 3 роки тому

    This was really amazing video...thanks for great help

  • @kasieeenda
    @kasieeenda Рік тому

    this is such a genius explanation, thank you!

  • @cbbhvjc
    @cbbhvjc 4 роки тому

    An excellent presentation on this subject!

  • @austinmital-skiff8947
    @austinmital-skiff8947 4 роки тому

    So incredibly helpful and well put together. Thank you so much

  • @sakshijuneja5520
    @sakshijuneja5520 4 роки тому

    You explained it so well .... really appreciated .

  • @isabelguillermo1574
    @isabelguillermo1574 5 років тому

    Your explanation helped me to finally understand this. Thanks!!

  • @KishoreKumar-uw4iy
    @KishoreKumar-uw4iy 3 роки тому

    Wow what a clear full explanation 💯👌

  • @isaacjones748
    @isaacjones748 5 років тому

    Thanks man! Got an essay on this tomorrow and your vids are a godsend

  • @XIconic
    @XIconic 5 років тому

    You have such an amazing medicine channel. I wish you can keep making more of these high quality education videos! Your animation and graphics are so clean and thorough. These are videos I would want to learn from as a primary source of information for diseases, medications.

  • @msme9790
    @msme9790 2 роки тому

    Very intense but well done

  • @maferr9199
    @maferr9199 6 років тому +2

    Sooooo helpful! When will part two be uploaded?!? 😭❤️😭❤️😭❤️

    • @Medicurio
      @Medicurio  6 років тому

      Will be done by the end of December!

  • @mrfantasticguy6385
    @mrfantasticguy6385 6 років тому +1

    Great to see you back! Love your videos and hope you get a whole lot more subscribers

  • @vannhivuong4242
    @vannhivuong4242 5 років тому

    Tks a lot. This makes pharmacology become insteresting

  • @harrowguy6379
    @harrowguy6379 6 років тому +2

    very informative video well done

  • @doesntfeellikehome4229
    @doesntfeellikehome4229 5 місяців тому

    this lecture is what i want.. perfect

  • @DavidJohnson-wc1lb
    @DavidJohnson-wc1lb 6 років тому +1

    Excellent video

  • @IvanEedle
    @IvanEedle 5 років тому

    Super interesting, but not terribly surprising: Your explanation of hyperpolarisation as a means of blocking neurotransmission is similar to how a semiconductor transistor 'switches off' and blocks current. Search 'flow of holes in transistor' for the analog.
    Depolarisation, being the opposite, is analog to flow of electrons in the transistor which then 'switches on' and allows flow of current.

  • @bellarodrgz
    @bellarodrgz 5 років тому +3

    This video is extremely helpful thank u ❤️

  • @raquelfranco6869
    @raquelfranco6869 6 років тому +1

    Hello Medicurio, I am currently a first year pharmacy student at the University of the Pacific and was wondering if I can use a few of your graphics in this video for my class presentation on the opioid crisis. Please let me know as soon as possible. Thanks!

    • @Medicurio
      @Medicurio  6 років тому

      Hi Raquel, yes you can use these graphics. I'm very sorry for the delay in response, I never got the notification of your comment until today. Hope your presentation went well :)

  • @haseebhussain3124
    @haseebhussain3124 3 місяці тому

    Wonderful explanation ❤

  • @hawk4225
    @hawk4225 5 років тому

    hey, i know you havent made a video in a while, but could you make one talking about seizures and how the medicine stops seizures from happening again.

  • @jungmusohn5230
    @jungmusohn5230 5 років тому +2

    Exam in 7 hours, found this as amazing summary and review. thank you so much

  • @alextmason1
    @alextmason1 3 роки тому

    Such a brilliant explanation, thank you so much!!

  • @jodyyamada3726
    @jodyyamada3726 5 років тому

    this was awesome! Thank you for making this video! 4 hours in my therapeutics class and it wasn't even close to being this clear!

  • @B0Sajwah
    @B0Sajwah 6 років тому

    Thank you for this video and cant wait for part 2!

  • @catmclaren6943
    @catmclaren6943 6 років тому

    I found your channel a few days ago and I'm glad to see you're still creating content :D Good stuff!

  • @siddhimarathe932
    @siddhimarathe932 4 роки тому

    Wow Man!!!!! Thankyou very much. You are saving lives out there ❤❤

  • @tasha3757
    @tasha3757 5 років тому +5

    Well done! You're really making quality content. I wish this channel well!! 👍
    SUBSCRIBED!

  • @pilarguevara5178
    @pilarguevara5178 4 роки тому

    Best explanation ever. Thank you very much.

  • @thagiven1
    @thagiven1 2 роки тому

    wow, just wow. Amazing work!

  • @britishbard
    @britishbard 6 років тому +1

    This is an amazing channel! This has really helped me in my studies and I hope that this channel builds upon its success, please keep going!

  • @wahidwithanapron1467
    @wahidwithanapron1467 5 років тому

    It's just mind blowing!!!! Awesome video