Diabetes Mellitus | Clinical Medicine

Exclusive USMLE Step 2/PANCE Lecture… for FREE! Become a member on our website for more Premium Resources: ninjanerd.org/lectures/diabet...
Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Diabetes Mellitus. We will discuss the pathophysiology, differentiating between Type 1 diabetes, characterized by autoimmune destruction of insulin-producing beta cells in the pancreas, and Type 2 diabetes, resulting from insulin resistance and relative insulin deficiency. The lecture will include a discussion on the clinical manifestations, such as polyuria, polydipsia, and unexplained weight loss. The digital presentation will begin with the diagnostic approach, highlighting the importance of fasting plasma glucose levels, the oral glucose tolerance test, and glycated hemoglobin (HbA1c) measurements. Finally, we will review management strategies for Diabetes Mellitus, emphasizing the role of dietary management, physical activity, blood glucose monitoring, insulin therapy for Type 1 diabetes, and oral hypoglycemic agents for Type 2 diabetes. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Diabetes Mellitus Introduction
0:18 Pathophysiology of Diabetes Mellitus
8:56 Complications/Issues with Diabetes Mellitus
21:40 Diagnostic Approach to Diabetes Mellitus
25:21 Treatment of Type I Diabetes Mellitus
30:07 Treatment of Type II Diabetes Mellitus
35:23 Treatment of Diabetes Mellitus Complications
44:35 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Diabetes Mellitus | Ty...
• Diabetes Mellitus | Ty...
• Diabetic Ketoacidosis ...
Ninja Nerd Website | ninjanerd.org
Ninja Nerd Podcast | podcast.ninjanerd.org
Ninja Nerd Store | merch.ninjanerd.org
/ ninjanerdlectures
/ ninjanerdlectures
/ ninjanerdlectures
/ @ninjanerdsci
/ discord
#ninjanerd #endocrine #diabetesmellitus

[@mark46]

That's millions of times better than the board; the information is more organized here, and you're more at ease. Still, we have no complaints, as it's free.

[@inessashlifer8026]

Thank you for taking your time and creating these medical lectures in the most comprehensive, yet easy-to-digest ways.

[@sandiyaparthasarathy7119]

This video made my physiology easy.Far better than books. Thanks a lot sir. I really understood the topic .It is well organized in a manner that we can understand without any confusion. Flow chart of diagnosis and treatment is awesome.👏👏👏👏👏👏👏👏👏👏👏Everything that we need about DM in one video. Great work sir. Hats off👍👍👍👍👍

[@kamilmahmood4346]

You lectures are directly going into the brain when you are explaining on whiteboard with your brilliant hands. So please keep up on whiteboard

[@hehehhe5461]

this is soo good, described everything from pathology to how it impacts everyday clinical scenarios. thank you a bunch

[@michelleguthery6514]

I absolutely love your videos. You aid me in actually understanding the foundation to things.

[@dm9392]

Pleaae bring back the white board!

[@rumaisashahid]

Thanks a lot for breaking it into digestible chunks!!

[@ayezawaseem3634]

Thankyou for these! You surely are a life saver. I love how easily these summary charts in your videos help me correlate it to a real life patient

[@omoooooo4275]

Look what I found! A fresh video! Thank you for your efforts!

[@marwaelg6323]

This really came at the right time ! Thank youuuu

[@jamesm3671]

This clinical medicine lectures are Awesome,keep them coming,,Thank you

[@rokayaenafielmetni5232]

i honestly am fine with both the board and this . Im just here to learn and grateful for the help !

[@miguelangelperez2849]

Thanks ! Very complete revision

[@surfergirl22330]

The best always! Thank you!

[@mariamaboutouk8849]

Thank youuu🎉 I like the clinical med videos so much

[@b.a.m3165]

Zach if u don’t mind …
I want to enter your brain to see how he made any topic easy & digestible to be understood
Thanks 👏🏻

[@sanjith1179]

I'm pratheesh from India (Tamil Nadu).big fan of you sir.say one hii sir..

[@ok6109]

Why are you every where bro ?😂

[@maryjaneofor2972]

Thank you Sir.. Understanding wasn't hard with this. Thank you!

[@user-nq7ie8od4f]

Thank you so much

[@valviv]

Great video, thanks Ninja Nerd!

[@LinaGQ]

Youre literary an angel sent from God to us to provide us with your wisdom and your teaching talents. Thank you for all that you, May God keep blessing you in many different ways.

[@queteimporta7049]

This is an awesome video. Very helpful and understandable. I just want to say that I prefer the board videos where you explain more detailly. But you are the best ❤

[@ShowBoySagar]

Thanks for uploading 3 dyas before my exam

[@gabrielasion]

Thank you very much!

[@charmondkingren2105]

Very helpful. Thank you

[@user-lh2lq4et3e]

This is better than the whiteboard for meeeeeee, THANK U SO MUCH

[@vincentcyrilliansantoso9858]

ZACH, please make more of the "study case" playlist!
IT'S UNDERSTANDABLE AND MAKE SENSE A LOT!
i'm looking forward to see more of the playlist!
Keep it up, God bless you!

[@consideration8881]

Oh just realized Zach renewed the diabetes video. That's cool!

[@hala._bee]

Thankyou sir❤
New method is superb ❤

[@nicolebarwise917]

Thank you! You are amazing.

[@vLion]

Thanks

[@idontspeekgeek72]

Hey! i would love to see a DKA vs HHS video please! I am studying for my PCCN. i love watching your videos because i can actually understand the "why" behind things. thanks for all your time put into these videos!

[@abcjunn]

He has one video published long time ago when i was still in med school.

[@Kittyslay-ox4tk]

Thanks. The content and your clear presenting skills are brilliant. Also appreciate the modern, digital diagrams. Much more easier to absorb the complex info.

[@maryjaneofor2972]

You said it all👍

[@caitlynkay5066]

This is a great video! Please consider doing a DKA and HHNS video! This would be extremely helpful as a new endocrine APN

[@DeVergam]

Make a playlist with all the clinical videos please

[@FRANKSTEPHENNKOONGE-ic2bw]

This is better than the white board, becoz here the information is more organized and flowing, which keeps me on track ...

[@sumaya2690]

Im from kurdistan and i want to say thank you sooo much for your detail information ,Im in dental collage 🦷 and needed your information to understand .✨✨🙌🏼

[@PowerrPundit]

Amazing lecture!

[@jeremiahbaker6396]

Thank you sir

[@israhamid4408]

Clinical medicine lectures are life savers 😊

[@shahiramohammadi7284]

Like always great

[@olyashepova5988]

Thanks!

[@XayatiAbdifatah]

thanks ninja 😊

[@MudasirKhan-cb3fp]

thanks

[@mawunyokukah6611]

Great work ❤

[@allthingsecho]

Please revert back to the original whiteboard Easy to get bored with thus this format.

[@ronaldnthwana476]

Yes please

[@jennykimat1954]

I agree

[@user-mg1qp5jk7x]

PLEASE 🙏

[@naveedkhannk2325]

Pls sir

[@samphonnetgamgee5625]

No! This format is clearer, only that it should be larger, as we don't see anything.

[@singletrak1]

In DKA even if the AG is closed don't you want to continue the ins gtt until the BG's are stable for 24hrs or ar least 3 BG's

[@deborahopabola7202]

God bless you

[@naftarywanderi2134]

I think when managing type 2 Dm you should start with low dose metformin then taper up after 3 months based on A1C before adding a second OHGA?

[@love2shop1996]

Will there be notes posted soon for this?

[@il3mendo]

How do you differentiate acetone, metabolic acidosis and DKA if you carry the hla dr3 in child ?

[@clementmasai7487]

Where is the dka vs hhs video? Once watched but not seeing it anymore

[@sarahsandy2204]

Honestly AMAZING!! LOVING this new series - thank you so so much :))

[@user-dm6ib6kc7h]

Look who comes back💥💥❤

[@Mac61202]

What about later stages of T2 diabetes where insulin production by the body is greatly decreased (or completely gone) and insensitivity is increased. For instance, what if someone came to the ER due to dizzy spells and an inability to walk short distances without fainting but previous to that hadent seen a doctor for over a decade. Would their T2 diabetes have progressed far enough to warrant lipolysis and ketone bodies in the blood since glucose wouldent be a viable source of energy anymore. Would we then see symptoms of DKA in T2 diabetics similarly to T1 diabetics? My thought process is that there would be protein and glucose loss through glomerular damage which would pull water from the system. Patient becomes dehydrated and begins exhibiting orthostatic tachycardia and only visits the ER when the issues become prevalent enough.

[@Anarchers]

I love the squeaky whiteboard pens! :)

[@iliyaghiyasvand]

you Are second to none ❤

[@nasiruddinnabil8922]

Can anyone please give me pdf of this class!?

[@wangari.t]

Also the levels of sorbitol increase due to a dysfunction of the enzyme SORBITOL DEHYDROGENASE, which converts sorbitol to fructose.

[@aryasree8471]

Great ❤...

[@vaibhavbarfa3988]

Great

[@j0425]

I can't see clinical medicine playlist? Sir

[@bulletproofboulevard]

life saver

[@il3mendo]

Can you please make a video about Celiac disease ? ❤

[@grumpyinbrooklyn6347]

You should add other types of diabetes in the future, particularly MODY and 3c. I suspect MODY is grossly underdiagnosed and thrown into the T2D or T1D types way too much!

[@LYVwithLYN]

Please do the white board.
Great lecture.

[@ZeyadAlweher]

White board still my favourite teaching way.. Regards

[@vastv2024]

Legend

[@rafikijustin7903]

Love

[@I_am_Anne]

I am actually crying because I finally understand. Thank you.

[@swadud1937]

7:57 - Why can glucose not be utilised in diabetes? Surely the high glucose content in the blood doesnt require insulin to enter cells via facilitated diffusion using GLUT1 receptors? What is meant here by not being able to utilise carbohydrates?

[@francescopaolofabozzi1592]

I think that GLUT1 alone cannot provide enough glucose for some tissues to use, for example muscular tissue. That's why insulin reduction determines metabolic switch to lipolysis.

[@craciunandrei9755]

Because the insuline resistance , the receptor cannot be acctivated properly and GLUT molecules cannot go into the membrane

[@mertgundogdu211]

YOOU ARE LİFE SAVIOR

[@mfonufot1328]

The fonts on the presentation are so tiny and not clear, I prefer the white board

[@nancyrajyaguru]

Sir,You didn't include 1.5KPD and 1.5 LADA

[@khayrkafaafi8779]

Please let’s reverse back to the use of our white board learning module this would give us the real classroom room learning experience, something that really marked different than any other learning platforms( if so less) 😢 .

[@MEDICO5912]

❤❤❤❤

[@MudasirKhan-cb3fp]

love u

[@mohammed.h.j]

Please bring back the white board

[@jewelsaju5168]

❤❤

[@ece4038]

Süper

[@israhamid4408]

❤

[@subayyalkhan5814]

Sir this method isn’t working like your previous method on white board sir please revert back to whiteboard plzzzzzzzzzz

[@royal1395]

👏🏽

[@ahmedluay5366]

Where is Old DKA video 👀💔

[@user-ti8uo9ku5i]

I am Ayushi from India

[@abhaysudhi7485]

How many views does it have now?

[@abhaysudhi7485]

1.2k

[@nakkarahul6118]

12k

[@mytop1054]

Why do u delete the old video🙄🙄🙄

[@NinjaNerdOfficial]

It is in retired playlist not deleted

[@sumedhahaha]

8:51

[@shammshtiwe8159]

Please pleeeaassseeee revert ti the whiteboard that is what make ur identity 🥺🥺🥺🥺🥺💔💔

[@elina4ka47]

thats cool but ... we want the board back :(( #oldschool

[@Littlejigs_official]

Zach !! White board is better than this format

[@user-zz9iw5ti2b]

White board was better brother!

[@Dr.Hassankhan]

Please turn to whiteboard, this format is boring

[@nutansharma4369]

Chalk and talk is better not this

[@drzz2]

Best ninja 🥷

[@saxgirlhornboy6458]

A1c must be > 6.5 to establish diabetes? 🤔
How many eyes, feet, kidneys, etc., would be put at risk by this high bar?

[@saraQasim-dn2vh]

marry me🥹🤎

[@iHATEbigots666]

it can take wayyyy to long to find out you have type 1 diabetes

[@ShemMwangi-no8nz]

Please turn to whiteboard,this format is boring

[@charmondkingren2105]

Please be appreciative for the time, effort and costs of a thoughtful and generous teaching presentation.