CRISPR-Cas9 : Introduction and discovery

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  • Опубліковано 24 січ 2020
  • This video is the introductory video of my CRISPR playlist which tells you the story that how CRISPR was discovered.

КОМЕНТАРІ • 103

  • @ArchanaAmba
    @ArchanaAmba 2 дні тому +1

    thank you ,a simplified explanation of a complicated procedure

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 дні тому

      learn how it is performed in the lab ua-cam.com/video/pNseb_U6gu0/v-deo.htmlsi=0QGd3UeMcEAhsJlL

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 дні тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @above7846
    @above7846 Рік тому +4

    Thank you so much for teaching me all this!! Your 1:1 video teaching was very helpful!

  • @akshaykadem316
    @akshaykadem316 4 роки тому +15

    One of best educational Videos present in UA-cam👍👍

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +2

      Please share among your friends and colleagues and help me to reach big audience

  • @sarahmwashomah
    @sarahmwashomah 3 роки тому +12

    Such a fantastic explanation! Thank you so much; its helping with post grad. dip.

  • @RandomnessVortex
    @RandomnessVortex 2 роки тому +6

    That helped me so much on my science fair project! Thanks and great job!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Glad to know that my content was useful....please share my channel link with your friends and help me to reach big audience

  • @kamarsedik1448
    @kamarsedik1448 10 місяців тому +1

    عظيم جداً .... شكراً جزيلاً

  • @ashokkasdekar9382
    @ashokkasdekar9382 2 роки тому +10

    Your explanation and presentation are very nice and helpful for understand to this topic... thank you very much sir.🙂

  • @meghashreeguha99
    @meghashreeguha99 10 місяців тому +1

    Thanks a ton ❤. You make things so simple !

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 місяців тому

      Please share my channel link with your friends and help me to reach big audiance. Don't forget to checkout the part 2 of this video

    • @meghashreeguha99
      @meghashreeguha99 10 місяців тому

      @@animatedbiologywitharpan yes sure!

  • @YaNaBiology3004
    @YaNaBiology3004 4 роки тому +2

    Amazing sir. wonderful explaination

  • @above7846
    @above7846 Рік тому +2

    Thank you very much for tutoring and sharing the presentation me and tutoring

  • @shashios1236
    @shashios1236 4 роки тому +6

    Ur vdos r always.very knowledgeable.......keep it up....

  • @alexanderf5497
    @alexanderf5497 3 роки тому +1

    Wow, that was amazing!

  • @ahilasenthil1256
    @ahilasenthil1256 3 роки тому +1

    Clear explanation. Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share my channel link with your friends and help me to reach big audiance

    • @ahilasenthil1256
      @ahilasenthil1256 3 роки тому +1

      @@animatedbiologywitharpan Definitely. It is my pleasure.

  • @oggky
    @oggky 3 роки тому +2

    How do you make this animation??

  • @tamilbiology5078
    @tamilbiology5078 3 роки тому +2

    Interesting concept!!!

  • @sijinmathew6299
    @sijinmathew6299 3 роки тому +5

    Bro your sound is very nice than others😍and also good presentation 🔥❣️

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share among your friends and colleagues and help me to reach big audience

    • @sijinmathew6299
      @sijinmathew6299 3 роки тому +1

      @@animatedbiologywitharpan yes i will🔥👍

  • @urvashianand9399
    @urvashianand9399 3 місяці тому +1

    Superb explanation..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @urvashianand9399
      @urvashianand9399 3 місяці тому

      @@animatedbiologywitharpan ofcourse I'll share it with my friends

  • @selvakumarr7894
    @selvakumarr7894 3 роки тому +1

    Excellent

  • @vandanaanjana5643
    @vandanaanjana5643 Рік тому +1

    Must say very helpful and good 👍

  • @rubenangelvarisco9719
    @rubenangelvarisco9719 3 роки тому

    Incredibile!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      ua-cam.com/channels/4IpyopsGWSjaPACNTZLuqg.html please subscribe to my second channel as well

  • @noblekurian
    @noblekurian Рік тому +1

    Is it a hypothesis? The bacterial immune system mechanism

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому +1

      Yes, CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a bacterial immune system. It provides bacteria with the ability to defend against viral infections by storing small segments of viral DNA and using them as a template to recognize and destroy viral DNA in subsequent infections.

  • @yasmeenzoeb4248
    @yasmeenzoeb4248 Рік тому +1

    V well articulated

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @Nickel2010
    @Nickel2010 3 роки тому +1

    Is this used for the Covid-vaccines?

  • @user-vf6jr3en9l
    @user-vf6jr3en9l 6 місяців тому +1

    you said at 1:38 that the viruses have developed a defence mechanism should it be that the bacteria develops the defence mechanism

  • @junaidchoudhary9569
    @junaidchoudhary9569 3 роки тому

    Soo helpful animation ....

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      ua-cam.com/channels/4IpyopsGWSjaPACNTZLuqg.html please subscribe to my other channel

  • @perfect_religion8525
    @perfect_religion8525 3 роки тому +1

    Sir your vedio is amazing

  • @bio366geethasankar7
    @bio366geethasankar7 6 місяців тому +2

    🙏🙏

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  6 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @dak77
    @dak77 Рік тому +1

    CRISPR-Cas9 ; Yaradılışı hacklemektir.

  • @asfakamal9787
    @asfakamal9787 4 роки тому +1

    👍👍

  • @hagermohamed8095
    @hagermohamed8095 2 роки тому +1

    Can i get this presentation?

  • @homairaarian
    @homairaarian 2 роки тому +1

    How get pdf from you?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      I have a Facebook page (same name as my UA-cam channel) where related notes are available

  • @KELVIN-ir8kh
    @KELVIN-ir8kh 2 роки тому +1

    VERY NICE

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance

  • @ani_dps11
    @ani_dps11 3 роки тому +1

    Bro can u tell me book releted to crisper ??

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      There is no specific book chapter for it but you can refer to review articles

    • @ani_dps11
      @ani_dps11 3 роки тому

      @@animatedbiologywitharpan 🙏 bro

  • @meghadixit8954
    @meghadixit8954 3 роки тому +1

    Waiting for next part Sir...

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      ua-cam.com/video/pNseb_U6gu0/v-deo.html watch this

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Please share my channel link with your friends and help me to reach big audience

    • @meghadixit8954
      @meghadixit8954 3 роки тому

      @@animatedbiologywitharpan yes I will......👍great job .you deserve it

    • @meghadixit8954
      @meghadixit8954 3 роки тому

      Sir ,if have made video on nanotechnology ,plzz send the link . Otherwise plzz make a video on that

  • @ieb99
    @ieb99 2 роки тому +1

    Thank you sir for this video it help me with my project , I have presentation and i try to make ppt like ur vid it too hard , can u please share it with me to Presents it

  • @saisusmitha2849
    @saisusmitha2849 3 роки тому +1

    Bacteria has the defence mechanism against virus right??? 1:38

  • @zaxmito2214
    @zaxmito2214 2 роки тому +2

    Awesome video sir i have a project on it and it helped me a lot. It would be really better if I could contact you..... ☺

  • @ronaldbravo1323
    @ronaldbravo1323 4 роки тому +1

    can this tecnologi Cure Cancer ?

  • @treemanzoneskullyajan711
    @treemanzoneskullyajan711 2 роки тому +1

    Nice vid

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

    • @treemanzoneskullyajan711
      @treemanzoneskullyajan711 2 роки тому

      @@animatedbiologywitharpan sorry 😐 I don't have any friends anymore mate.

    • @treemanzoneskullyajan711
      @treemanzoneskullyajan711 2 роки тому

      @@animatedbiologywitharpan actually I might be able to send it to 1 or 2 guys I talk to now and again though

  • @we_r_2big2fail
    @we_r_2big2fail 4 роки тому +6

    Excellent video... My first one of yours.
    Just some constructive criticism:
    1. Practice chunks of the video first before recording, that way we can't tell if you're thinking about the next piece of info, it's just a smooth transition from point to point, no distractions. Record yourself, listen, repeat. Then do a final take after that.
    2. As you practice, find the pronunciation of words that would be as neutral English as possible, since the majority of English UA-cam watchers are US/UK based- i say this because, for example, instead of saying 'phage' ( US: feh - ee - j), you end up saying 'fudge' (the delicious chocolate treat) and it's distracting so i have to rewind to make sure I'm understanding what you're saying.
    3 there are good video editing programs that are low cost and on an iPad you can do wonders (KineMaster is one, and it's probably around $20 USD for a lot of editing power).
    Don't ever stop and thank you for this!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +1

      Thanks for these elaborated feedbacks ,it would help me to improve my channel content

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому

      Please share my channel link with your friends and help me to reach big audience

  • @gujjarsab1215
    @gujjarsab1215 2 роки тому +1

    SIR CAN YOU PLEASE SEND ME THE NOTES OR ASSIGNMENT.

  • @GilchrestJohn
    @GilchrestJohn 3 роки тому +1

    At 1:37 you said viruses developed a defense mechanism...................should this not be Bacteria have developed a defense mechanism?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Upss .....its just a slip of the tongue..

    • @GilchrestJohn
      @GilchrestJohn 3 роки тому

      @@animatedbiologywitharpan Thanks for the reply. Really good video & explanation:)

  • @manda6619
    @manda6619 2 роки тому +4

    Why change God's DNA?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +10

      To cure disease

    • @manda6619
      @manda6619 2 роки тому +1

      @@animatedbiologywitharpan no excuse. God made us in HIS image. Not for science to ruin it. Aka Covid vaccines 😓 I personally don't want to go to hell now.

    • @danielmoore4024
      @danielmoore4024 Рік тому +1

      @@animatedbiologywitharpan
      No, this is disgraceful and evil!
      Stop disguising your eugenics. You're already aborting more black people than white, you already disallow disabled people to be born, more LGBTQIA are aborted than straight, more females are aborted than males, all advertisements of designer babies are images of white males.
      There's advertisements of anti aging which has nothing to do with sicknesses or diseases, if it was only about sicknesses and diseases you wouldn't of ever thought of touching the human germline.
      So don't bother denying this is racism, sexism, ableism, communism, eugenics and capitalism.
      You do not have the right to mess with a person's genes just because you perceive something about them as a "problem".
      Autism is not a problem, you claim you value all humans equally, since you want to rub us out of existence you clearly do not see us as equal, you are full of discriminatory thoughts like Hitler doing eugenics. The problem is clearly your view of autism and other primarily genetic conditions. I love being autistic, I wouldn't give it up for the world.
      Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution."
      Do you really want to bring us to extinction?
      Evelyn Fox Keller explains:
      "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution."
      The mutants behind autism and other conditions like Down Syndrome offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction.
      Psychologist Howard Gardner warns:
      "With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities - eg. spatial or pattern recognition skills - might be placed at risk were we to target our interventions specifically at reading disorders."
      Do you really want to destroy all alternative perceptions and ways of thinking? Don't you know how many abilities you are going to destroy and how impoverished you are going to make our world because of your cultural myopia?
      Each time you have tried playing God you have only caused harm. Who caused the climate change? Scientists playing God trying to control nature, did you Gods anticipate the climate change?
      You are not only messing with humans, this whole earth is interconnected, you are messing with the entire ecosystem, with all life. How many species have been brought to extinction because of humans manipulating nature, there's endangered species today thanks to humans manipulating nature.
      If we fail to understand and take care of the natural world, it can cause a breakdown of these systems and come back to haunt us in ways we know little about. A critical example is a developing model of infectious disease that shows that most epidemics - AIDS, Ebola, West Nile, SARS, Lyme disease and hundreds more that have occurred over the last several decades - don’t just happen. They are a result of things people do to nature.
      The diseases you claim you want to cure were caused by doing this, so why are you doing it again?
      Was the world ready for COVID-19 to strike? I doubt it.
      World War II was caused by eugenics, why are you following Adolf Hitler's steps?
      Mutations are not random or accidental, malaria is endemic in Africa and Africans have developed mutations that protect them from malaria through adaptation, Europeans don't have these mutations, if a European goes to Africa they are more likely to get a disease. It was mutations that enabled the Europeans to survive the 14th century bubonic plague.
      Editing one gene may cure a disease but at the same time make them more susceptible to other diseases.
      Again, this is wicked and pure evil to think we don't deserve to be born just because we are different. CRISPR-Cas9 is a direct violation of human rights, especially human autonomy.
      Sort your discriminatory thoughts out and don't you touch us without our consent!

    • @jamesreagan9063
      @jamesreagan9063 19 днів тому

      An amazing presentation alright!
      Comments so full of accolades from those appearing to be working on their terms!
      Forging full speed ahead in a very hypothetical environment!
      Embarrassing implications for the ignorant!
      A OK for the plan, reaction solutions, of those, at our helms! Fight with Nature! / Protect dna

    • @jamesreagan9063
      @jamesreagan9063 19 днів тому

      ​@animatedbiologywitharpan That We have not begun to understand!
      Get a grip on the minimum of hypotheticals!
      Think in certain terms of glyphosate and its disruption of the plant it "means" to protect!