What are the main prescription medicines for opioid-induced constipation (OIC)?

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Gastroenterologist Dr. Jeanetta Frye, an expert on chronic constipation, discusses the main prescription medications available to treat opioid-induced constipation (OIC). These medications include lubiprostone, methylnaltrexone bromide, naloxegol and naldemidine. Dr. Frye explains how each one works to help relieve OIC, such as by blocking the effects of opioid medications in the digestive system.