Mitochondria, Apoptosis, and Oxidative Stress

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  • Опубліковано 2 гру 2024

КОМЕНТАРІ • 67

  • @mikameeka1221
    @mikameeka1221 6 років тому +5

    Thanks for the video! I'm writing a paper on caspases for my a college biochemistry course, and this was extremely helpful in understanding their role in apoptosis. I work in an undergraduate lab that studies caspase structure-function, but wanted to learn about caspases in a greater context. 10/10 would recommend :)

  • @howardlax5280
    @howardlax5280 10 років тому +22

    I so like this lecturer's voice. Soft and enchanting.

    • @janabb6586
      @janabb6586 8 років тому +7

      +Howard Lax are you serious? i found her voice to be so annoying, i couldn't stand her weird lisp....had to stop watching the video and go to another one about this subject lol

    • @eoinroberts8146
      @eoinroberts8146 8 років тому +2

      That's cool, my dude.

    • @ghayab7338
      @ghayab7338 6 років тому +1

      really ? I hated it it's so annoying

    • @panama2468
      @panama2468 2 роки тому

      @@janabb6586 imagine being this toxic and jealous

  • @akshitgupta1698
    @akshitgupta1698 5 років тому +3

    To summarise- Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family members regulate the release of cytochrome c proteins from the space between the mitochondrial inner and outer membrane that, once in the cytosol, activate caspase proteases that dismantle cells and signal efficient phagocytosis of cell corpses.

  • @jeffbridgewater8093
    @jeffbridgewater8093 8 років тому +2

    Great Video and information on cell death and the mitochondria. I recently found a way to help repair and create more mitochondria within your cells. Super excited about what we found. Again great video.

  • @michellecarlamaier1923
    @michellecarlamaier1923 9 років тому +5

    AMAZING VIDEO! Truly assisted with my understanding of oxidative stress and apoptosis. Thank you :)

    • @cf34shaw
      @cf34shaw 7 років тому

      Signal transduction history and significant

  • @1sarfarazahmed
    @1sarfarazahmed 3 роки тому

    Comprehensive yet concise. Thank you.

  • @xBangBangChuChuTrain
    @xBangBangChuChuTrain 9 років тому +6

    please do a video comparing the caspases ! :)

  • @vvhynh1549
    @vvhynh1549 9 років тому +4

    Really helped me with my Patho Class, thanks alot! also weird question but what kind of software/hardware (e.g. ipad? surface pro?) are you using? I would love to use to take class notes!

  • @DannyMercer1993
    @DannyMercer1993 10 років тому +3

    This is incredibly impressive!! Thanks!

  • @estelamino6356
    @estelamino6356 3 роки тому

    GREAT information THANKS

  • @abhirupbandyopadhyay5689
    @abhirupbandyopadhyay5689 7 років тому

    Educative for graduating students like me

  • @Rap4ever321
    @Rap4ever321 10 років тому +1

    Oh yeah, baby! Write that Caspase out suggestively ;).
    Hypothetically, if a lot of cells underwent apoptosis, could a healthy cell pick up enough cytochrome-C from its environment to accidentally trigger the apoptotic mechanism?

  • @meganmai8542
    @meganmai8542 8 років тому

    very eloquent explanation

  • @bibodude
    @bibodude 2 роки тому

    Hello, regarding the apoptosis during embryonic development, is it the pathway intrinsic or extrinsic?

  • @Daemon_intellectualis
    @Daemon_intellectualis 2 роки тому +1

    Can someone provide me a mechanism by which «mental» stress could end up to oxidative stress. I'd appreciate if there's a reference handy

  • @LivLifeCommandoStyle
    @LivLifeCommandoStyle 10 років тому

    Wonderful video!!

  • @blackphosphor
    @blackphosphor 8 років тому +3

    i looooooove your voice

  • @jackedbyrohit3236
    @jackedbyrohit3236 4 роки тому

    7:15 Role of mit. in Apoptosis

  • @alessandrafarias6906
    @alessandrafarias6906 7 років тому

    so cool... thank you

  • @mphat10
    @mphat10 5 років тому

    Why ROS make the membrane more permeable?

  • @brentwakefield5470
    @brentwakefield5470 8 років тому

    great video. FYI the second "p" is silent in apoptosis.

  • @milo0903
    @milo0903 8 років тому +2

    um...a bit fast? but that helped anyway! thank you!!

  • @Ahmed.r.a
    @Ahmed.r.a 8 років тому

    Can anyone tell me what's the name of the device he is using for writing on screen? any tips will be appreciated.

    • @NNOTM
      @NNOTM 8 років тому +1

      Presumably a graphics tablet

  • @claraschmidt360
    @claraschmidt360 3 роки тому

    great :)

  • @timeisrunningoutforthebeast
    @timeisrunningoutforthebeast 2 роки тому

    Thanks

  • @oogenesis12
    @oogenesis12 3 роки тому

    ROS is superoxide anion radical, hydroxy radical, hydrogen peroxide

  • @agathaso8624
    @agathaso8624 5 років тому

    thank you!

  • @mikajlod25
    @mikajlod25 7 років тому

    10 minutes to get to the main player! what?! thank god for 2 times speed

  • @ralfoxygen1374
    @ralfoxygen1374 7 років тому

    Already there is a new, German Vital Air 5+ device which is much better, more powerful and more effective than NanoVi (oxidative stress) !

    • @hopeplentifulmoon5560
      @hopeplentifulmoon5560 4 роки тому

      Ralf Oxygen 🤣Both are child’s play. If you really want to step your game up, I highly recommend NrF2(protandim and PB 125) supplements with the combination use of the BEMER device. This device has existed for the past 20 years in Germany and only in the US for the past 8 years. Originally registered as Class I device and in the process of going Class II.

  • @FatimaKhazaal534
    @FatimaKhazaal534 2 роки тому

    👏👏👏👏🌟

  • @srinivasanaravindhasamy5575
    @srinivasanaravindhasamy5575 5 років тому +1

    Read slowly mam. We are from medicine school.You can better to teach slowly. AND ITS MORE HELPFULL TOO....

    • @zaggedout
      @zaggedout 5 років тому +1

      pause the video lol

    • @hopeplentifulmoon5560
      @hopeplentifulmoon5560 4 роки тому +1

      Pop some GABA with a tall glass of filtered spring water, deep nasal breaths put the cations on and you WILL be able to follow better. I promise. 🙋🏻‍♀️

    • @josephdahdouh2725
      @josephdahdouh2725 3 роки тому

      Fun Fact: You can slow down the video, and most of medicine students listen to everything at x2 speed.

  • @engin7787
    @engin7787 5 років тому

    We would be able to understand what is talked about ,If you would care to speak a bit slower ,Thank you !

  • @ralfoxygen1374
    @ralfoxygen1374 6 років тому

    Vital Air 5+® device - most powerful and versatile of all
    Activated Oxygen Therapy machines in the world !

  • @Gigi_otter
    @Gigi_otter 8 років тому

    Did not help at all.... Well it helped me get confused.....

  • @zannatul23
    @zannatul23 9 років тому

    jasmine rana sounds bengali
    good video still

  • @ralfoxygen1374
    @ralfoxygen1374 7 років тому

    Reduce Oxidative Stress ("Free Radicals") with Vital Air 5+ device !

  • @petercruz1993
    @petercruz1993 9 років тому +8

    Khan is better :S

    • @ShinySephiroth1
      @ShinySephiroth1 5 років тому

      So this didn't use to be a Khan Academy vid? Interesting!

  • @jeffheslop3749
    @jeffheslop3749 8 років тому +2

    The second 'p' in apoptosis is silent so it's pronounced apo-tosis.

    • @eoinroberts8146
      @eoinroberts8146 8 років тому +5

      that's cool my dude

    • @panama2468
      @panama2468 2 роки тому +1

      They should remove the p from the word then

  • @sightseer2011
    @sightseer2011 7 років тому +3

    grinding voice. would rather listen to robot.

  • @davidcunningham2984
    @davidcunningham2984 6 років тому +3

    Most obnoxious distracting nonsensical speaking voices ever. Speech is sing song accenting words with no respect to meaning. Very obnoxious and distracting. Detached from audience, aloof.

  • @akshitgupta1698
    @akshitgupta1698 5 років тому +13

    To summarise- Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family members regulate the release of cytochrome c proteins from the space between the mitochondrial inner and outer membrane that, once in the cytosol, activate caspase proteases that dismantle cells and signal efficient phagocytosis of cell corpses.