Electron Transport Chain (Oxidative Phosphorylation)

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  • Опубліковано 17 лип 2019
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

КОМЕНТАРІ • 928

  • @andrewfayi9448
    @andrewfayi9448 3 роки тому +1402

    This takes "The mitochondria is the powerhouse of the cell" to a whole new level.

    • @gdsal2552
      @gdsal2552 2 роки тому +6

      😂

    • @iitsmeneeka8565
      @iitsmeneeka8565 2 роки тому +17

      This is all still so confusing to me and a lot to remember I’m just gonna leave my bio class in gods hands it’s like I don’t even know how to study this stuff. I’ve listened to UA-cam recordings of my teacher quizlet and when it’s time to do the work/take a quiz I don’t remember anything

    • @nabs9423
      @nabs9423 2 роки тому +10

      @@iitsmeneeka8565 you got this bro, just give it your best!

    • @ecstasylol6427
      @ecstasylol6427 Рік тому +9

      @@iitsmeneeka8565 same here. i take economics, bio and chemistry and its honestly terrifying that economics is easy for me compared to chem and bio, since i hear people say economics is difficult, oh boy let me introduce you to STEM

    • @bigarj8182
      @bigarj8182 Рік тому +2

      @@ecstasylol6427 🤗if only everyone realised this

  • @Salsoci
    @Salsoci 4 роки тому +1586

    Most clear explanation I have ever encountered regarding oxidative phosphorylation!

    • @lilybushra6901
      @lilybushra6901 4 роки тому +2

      justbia14 trueeee!!

    • @Crystal_Scott
      @Crystal_Scott 3 роки тому +3

      @@lilybushra6901 Truly

    • @gracemasiku5243
      @gracemasiku5243 2 роки тому

      For reallll

    • @jermsbestfriend9296
      @jermsbestfriend9296 2 роки тому

      Can you explain what the complexes are? None of this makes sense to me because of the lack of explanation of what the many complexes are. Maybe they have their own videos?

    • @manuelramos975
      @manuelramos975 Рік тому

      Hi I am new to Dirty medicine, how can I view or search all videos?

  • @Yusuf-hy4pz
    @Yusuf-hy4pz 3 роки тому +1115

    If you want to remember the order of inhibitors of the ETC think "RACCOON"
    R otenone - Complex I
    A ntimycin - Complex III
    C yanide - Complex IV
    C O - Complex IV
    O - ATP Synthase
    No coupling - uncoupling agent

  • @ragavendars5194
    @ragavendars5194 3 роки тому +463

    Why weren't you around during the 1st year of my medical school. Even Harper's Biochemistry doesn't deliver such a clear cut explanation. I will never forget this in my entire life. Its etched in my brain forever. Thank you. Huge respect !!!

    • @harvey4892
      @harvey4892 2 роки тому +10

      For real! I tried Harper’s and Lippincott now in my first year med, but it was this explanation that made it make sense.

    • @lmriana
      @lmriana 2 роки тому +5

      Please try Lehninger's Principle of Biochem as a reference book if you haven't already. Vander/Harper/Stryer does a good job but Lehninger helps to build the foundation of the concepts.

    • @user-hn9qg5qm3o
      @user-hn9qg5qm3o Рік тому +3

      Why is the NADH from glycolysis got 3-5 ATP??

    • @mtbslayer5506
      @mtbslayer5506 Рік тому +3

      On God man explained it so well I understood it at 1am the night before my exam

    • @user-ru1qf4nf2i
      @user-ru1qf4nf2i Рік тому +2

      @@user-hn9qg5qm3o Bnb explains this. If 2 NADH produced in glycolysis are transported to mitochondria via malate shuttle, they remain to be 2 NADH; if these 2 NADH are transported via Glycerol-3-P shuffle, 2 NADH are converted to 2 FADH2, decreasing 2 ATP.

  • @dilawaiznazir1325
    @dilawaiznazir1325 4 роки тому +471

    this was the best explanation ever .... literally u saved me from reading an entire lesson

  • @synthechehyacinthperlas8160
    @synthechehyacinthperlas8160 4 роки тому +136

    Never been so certain and confident about this topic but because of your video I've finally understood the whole basics of oxidative phosphorylation . THANK YOU SO MUCH😊

  • @WaniyaS-xm9zt
    @WaniyaS-xm9zt Місяць тому +7

    This guy should be given a national award for simplifying ETC the way he did

  • @kyledebruyn703
    @kyledebruyn703 Рік тому +12

    Im so impressed with dirty medicine. I always skipped these videos thinking it would be difficult. But I cant believe their videos are actually the most explanatory, detailed and easy to understand

  • @mauresmith4347
    @mauresmith4347 4 роки тому +26

    This video literally helped me understand how to electron transport chain work! Other videos I watched were pretty confusing. Thank you!!

  • @HarrisiQureshi
    @HarrisiQureshi 3 роки тому +9

    I want to echo the other comments. This was the CLEAREST video I've seen on the ETC & Chemiosmosis. Thank you!!!

  • @khhtutor
    @khhtutor 4 роки тому +101

    WOW! The way u present with the inhibitors of ETC is remarkable, precise while detailed. I’ve utilized this material to teach my SAT BIO students. Thanks a lot.

    • @gretathunberg6197
      @gretathunberg6197 3 роки тому +3

      Just have them watch this video lmao

    • @dbuc4671
      @dbuc4671 3 роки тому

      @@dinamohamed187 well 7 8 9 not 7 8 8

  • @jseanbrooks1
    @jseanbrooks1 3 роки тому +9

    I've been trying to learn this for years. Hands down one of the best videos I've ever seen. Thank you so much!

  • @gusforyou
    @gusforyou 3 роки тому +52

    Not only this video taught me about oxidative fosforilation, but also a new vocab. Thank you for this high yield material

  • @poorvansh.
    @poorvansh. 4 місяці тому +3

    The most clear, concise, magical, miraculous, heavenly explanation available for ETC in this whole wide universe, THANK YOU!!

  • @NO-ib1je
    @NO-ib1je 4 роки тому +4

    This was INCREDIBLE!!! Step by step, with pictures!!! I learned so much. Thank you!!!

  • @thebfunk5228
    @thebfunk5228 3 роки тому

    I really appreciate your light tone and the simplifying of things. It's not stress-inductive and helps organising the thoughts very well

  • @davidvazquez5200
    @davidvazquez5200 2 роки тому +17

    This video is almost 3 years old but I'm studying for my MCAT coming up in March and this has been one of the best explanations I've come across. Thanks so much

  • @fariborz607
    @fariborz607 4 роки тому +24

    after years only this video helped me master ETC watching it 3 times for USMLE step1,big thank you.

    • @simplyyjhez
      @simplyyjhez 3 роки тому

      wow, this is on the USMLE???

  • @workout9632
    @workout9632 4 роки тому +12

    I came into this video very confused by other videos, my book and especially my lecturer.
    I came out of this video with a very confident understanding in this topic.

  • @Sprizys
    @Sprizys 4 роки тому +32

    Thank you for explaining this in English, all of the other explanations I've found have been so over complicated.

  • @zukagavasheli9262
    @zukagavasheli9262 3 роки тому +4

    bro thank you so much, i though that it was going to be impossible for me to understand this topic, but with you explanation everything just made sense. you save lives of medical students.

  • @vincentb.pardilla2107
    @vincentb.pardilla2107 4 роки тому +34

    Your channel is a blessing!😍 Tomorrow is my reporting about cellular respiration ad this ETC was really annoying me. Now I finally get it,thank u so much.

  • @Ash_Nichole
    @Ash_Nichole 2 місяці тому +1

    By far the most concise video I've ever seen about ETS. Thank you so much!

  • @assefameshesha1388
    @assefameshesha1388 Рік тому +2

    I almost give up with biochem and came across this channel. Now I am inspired and unstoppable!

  • @minaalsaeedi6556
    @minaalsaeedi6556 4 роки тому +6

    been studying for a very long time , tried to understand this , never worked out for me , can't thank u enough , god bless u.

  • @sharonkende4774
    @sharonkende4774 3 роки тому +8

    This was so clear. Thank you. I really like the pictures, labels and repitition of key points. You are a good man

  • @amaliatsitsani7692
    @amaliatsitsani7692 2 роки тому

    Thank you Dirty Medicine Team! FINALLY got it after 8 years! Congratulations for your super help!

  • @esjhb
    @esjhb 3 роки тому +1

    The clearest explanation I've seen on YT. All I can say is thank you, thank you, thank you!

  • @Tzo19996
    @Tzo19996 4 роки тому +7

    I had such a hard time grasping this concept but your explanation made it so clear!

  • @nirmaladivekar2415
    @nirmaladivekar2415 2 роки тому +5

    Damn! Such a phenomenal detailed explanation. I literally checked 5 videos on ETC before this video. Now ETC is imprinted in my brain. Thank you, you really helped me for exams. keep the great work :)

  • @confuseacat4451
    @confuseacat4451 4 роки тому +1

    I really needed this video two years ago studying physiology - Glad it's here now and I finally understand the process.

  • @lovedetoi5910
    @lovedetoi5910 2 роки тому

    omygod... something that my professor wasnt able to explain in an hour, this guy just explained everything i needed to know in 16 minutes!! Thanks fam!! You are appreciated!!

  • @to181
    @to181 4 роки тому +5

    Very concise and clear. Great for MCAT level understanding. Love it

  • @AryaNandini
    @AryaNandini 4 роки тому +282

    tysm...i guess ,ths was the only video on oxidative phosphorylation which made this concept so clear!!!tysm to dirty medicine again

    • @amarian0177
      @amarian0177 3 роки тому +1

      L

    • @shubhankardas7791
      @shubhankardas7791 3 роки тому +2

      Exactly. College professors made me more confused while the topic is easy when I saw this video

    • @yiwenzhang8941
      @yiwenzhang8941 2 роки тому

      cannot agree anymore

    • @cecolina2301
      @cecolina2301 2 роки тому

      @@shubhankardas7791 exactly!!!!!

  • @alhasanmd7305
    @alhasanmd7305 3 роки тому +1

    My step1 is next week. I'm freaking out and not being able to sit and focus and your videos are helping me revise topics between panic attacks lol. Thanks man, love you.

  • @noicsutak1584
    @noicsutak1584 11 місяців тому

    Literally could not be a more clear, easy to understand video. Really awesome work.

  • @ofgraceandstarlight6401
    @ofgraceandstarlight6401 3 роки тому +6

    Finals are coming and this is a great help! I really appreciate the way you stitched the concepts together to form the big picture.

  • @anittasusanmathew7988
    @anittasusanmathew7988 3 роки тому +3

    This was such a life-saver. The concept is so clear now. ❤ Thank you so much.

  • @lolok6338
    @lolok6338 4 місяці тому +1

    I feel like I could cry rn, this is the best video I’ve ever seen for-what I thought was-a complex process. This is gonna save my life for exams!

  • @jackky6153
    @jackky6153 4 роки тому +2

    This is the only video that actually made me understand the electron transport. Thank you soooo much

  • @dreamydew2113
    @dreamydew2113 2 роки тому +3

    This is such a good video. You explained the biochemistry concepts so clearly and straightforwardly while explaining the reasons and goals for every processes,which gave me a bigger picture and helped me understand a whole lot better.Thanks a lot! Helped me a lot to prepare for my test!!

  • @Willland
    @Willland Рік тому +3

    Easily the best explanation I've heard on this concept, massive thank you

  • @favourobiora978
    @favourobiora978 Рік тому +1

    Not only is your video well detailed, it is very precise and straight to the point. Thank you so much❤❤

  • @discreet_street
    @discreet_street 5 днів тому +1

    best, clearest, most organised explanation of oxidative phosphorylation in existence. you have my sincere thanks.

  • @yogayantra
    @yogayantra 4 роки тому +18

    thank you so much! This is the first time that, finally, i get to understand it fully

  • @nikitambbs
    @nikitambbs 2 роки тому +3

    Hey! I am Indian medical student. Your content is awesome 👏 Today I understood what is Electron transport chain. Thanks 🙏🏻

  • @tipsandtricks8524
    @tipsandtricks8524 3 роки тому +1

    omg i have never been so enlightened about the electron transport chain thanks to your channel..... nice explanation.... clear and fluid..

  • @haarisamir1987
    @haarisamir1987 3 роки тому +3

    just the way you explain it is amazing. Finally, after reading so many books, I get this process. It's just hard to remember it all and 5 more units for AP.

  • @s3aweedbrain
    @s3aweedbrain 4 місяці тому +5

    it has been 2 years and i still keep coming back to this video. it is engraved in my brain

  • @KiaraNohely
    @KiaraNohely Рік тому +19

    Today I received my step 1 results and I passed. I truly wanna thank you for your content, your biochem series was pure gold during my prep and your drugs of abuse video made me score a couple questions on the real deal. Once again thanks sir!

    • @maeve175
      @maeve175 Рік тому

      manifesting this for myself x
      and congrats on the pass!! well deserved :)

    • @doctormalika5107
      @doctormalika5107 5 місяців тому

      Hey @kiara have you taken all dirty medicine from UA-cam only, ? Or anyone have to buy its subscription?

  • @renoleceesay7869
    @renoleceesay7869 2 роки тому +1

    This was perfect! I do not think it could’ve been explained any better! Thank you!

  • @vanessaescalera4117
    @vanessaescalera4117 2 роки тому

    wow. out of all the science classes I've taken, this is the clearest explanation. only 10 min and I am so shook

  • @noora782
    @noora782 3 роки тому +7

    I cried happy tears watching this video thank you from the bottom of my heart

  • @hchavarry
    @hchavarry 3 роки тому +7

    You're a God send, I've been watching so many videos from Khan Academy and AK Lectures and this was hands down the most clear, easy to understand explanation.

    • @DirtyMedicine
      @DirtyMedicine  3 роки тому +1

      Thanks, please share with your friends

  • @halfricandoll8662
    @halfricandoll8662 2 роки тому +2

    I’m literally so happy, I watched so many other videos on this and it was so confusing for no reason but this is so simple and easy to understand and remember! Thank you so so much

  • @neermita7587
    @neermita7587 3 роки тому

    You. Saved. My. Life. Thank you so much!! This explanation is godly. You're a fantastic teacher!

  • @juliorosales769
    @juliorosales769 4 роки тому +10

    Oh maiii gawddd this is beautifully done. You’re a genius I love you.

  • @kirivargas5023
    @kirivargas5023 4 роки тому +7

    you're literally a God-send thanks so much!

  • @aayushphadte
    @aayushphadte 3 роки тому +1

    This is the best explanation I have ever seen!!!
    Cleared all my concepts!
    Thanks alot Sir

  • @brandonopara7778
    @brandonopara7778 2 роки тому

    I cannot thank you enough for this video! The most clear explanation on YT!!!!!!!!

  • @defne7958
    @defne7958 3 роки тому +6

    As a student who studies medicine, I can say you're doing a great job!! Please keep going!

  • @carolyntran202
    @carolyntran202 4 роки тому +3

    thank you so much ! I'm actually feeling pretty confident for my test now!

  • @darkordie
    @darkordie 3 роки тому +1

    I have a test in the next 30minutes and I think of looking for something to watch to atleast get in the exam room with something then here's the dirty medicine video on Electron transport chain I watch it for 16minutes and it summaries the whole semester 💯🙏
    Thanks a million dude👊💪

  • @rushali9321
    @rushali9321 8 місяців тому

    Dr Dirty , What would we even do without you.
    Thankyou for making such HY videos with clear concepts

  • @cjbruce23
    @cjbruce23 4 роки тому +5

    Had to subscribe after such a thorough and clear video. Thank you so much

  • @lubnashaltoot5934
    @lubnashaltoot5934 Рік тому +95

    Mashallah you truely have a gift of clarity and eloquence when it comes to breaking something complex into simple terms and delivering it. Being knowledgable and having the talent of delivering that knowledge are 2 different things, and you have both.
    Thank you for helping all of us, May Allah reward you and bless you .
    Have you had any formal practice in teaching or do you practice on your own?

  • @tristanhansen7252
    @tristanhansen7252 3 роки тому +2

    You made this whole process so simple to understand! Thanks for the help!

  • @aubreymayearrieta9452
    @aubreymayearrieta9452 2 роки тому

    By far the clearest explanation about oxidative phosphorylation I watched. KUDOS!

  • @kappa4305
    @kappa4305 4 роки тому +13

    So here you seeing the best ETS vid on youtube hands down... always found it too complicated lol.

  • @Gg-er8db
    @Gg-er8db 3 роки тому +3

    wow! im amazed at how much I learned from a video than a professor in person/online course

  • @kpopsound_0123
    @kpopsound_0123 Рік тому +2

    I watch many videos for understand oxidative phosphorylation ...but this one is the most understandable explanation .... Thanku so much ☺️

  • @Bhagyashreetharkar10
    @Bhagyashreetharkar10 3 роки тому +1

    I searched many videos ...nobody could make it so simple and crystal clear like u did ...tq you ...lots of love from India

  • @iamloveandpeace
    @iamloveandpeace 4 роки тому +6

    The words you have used like "shuffling" and "lace the intermemberane" are vividly descriptive in understanding this beautiful nano machine.

  • @nadyaolivares3564
    @nadyaolivares3564 3 місяці тому +3

    Home king explained clearly in 10 mins what my prof couldn't in 5hrs

  • @paramabarua8008
    @paramabarua8008 Рік тому

    can't thank you enough. years of pending doubts is now resolved.🙂 thank you so much sir.

  • @drerpa3182
    @drerpa3182 2 місяці тому +1

    Was fan of your mneumonics , now the concepts has blown my mind. Thanks a lot. may god bless you !!!

  • @kendragadsby6766
    @kendragadsby6766 Рік тому +4

    This is a ridiculous amount of commercials for a 16 min video, but the information was very valuable so thank you.

  • @Olivia-xb8bm
    @Olivia-xb8bm 3 роки тому +59

    “extremely high yield” 😂😂😂🤚🏼

  • @srilaxmiudupa8684
    @srilaxmiudupa8684 2 роки тому +2

    Amazing sir!! This is absolutely wonderful! I understood each and every bit of it!! You saved an hour of prolix lecture!!!

  • @nellabozic6214
    @nellabozic6214 2 місяці тому

    I am so happy I found this, watched a lot of explanation videos for Electron transport chain and yet this one is, little to say brilliant. Thank you very much. Respect. Have no other words.

  • @ony8892
    @ony8892 3 роки тому +5

    Finally u saved me!!this helped me a lot 😂😂😂.

  • @hussein2002yes
    @hussein2002yes 3 роки тому +3

    Don't mind me if I copy the other comments and say "THIS IS THE BEST EXPLANATION OF THIS TOPIC"😍✨

  • @paolamatos9600
    @paolamatos9600 4 роки тому +1

    This video was so helpful!!! Best video I found for oxidative phosphorylation so far

  • @nemesisdeimos92
    @nemesisdeimos92 2 роки тому

    This was really wonderful. I am so grateful that you put this out there for all of us to learn from.

  • @EliltaWorkneh-ui6sg
    @EliltaWorkneh-ui6sg 4 місяці тому +4

    That is awo some👩‍🏫 but I have question when the electron carrier pumps protons it uses energy so it is active transport or not?

  • @alexvir
    @alexvir 4 роки тому +3

    +1 one on one of the best explanations of the ETC-oxidative phosphorylation. And I am a PhD in Biology, so ive heard many of them )))) You did not highlight why it is called phosphrylation though, so as I understand it, it is the use of O2 and addition of phosphate to ATP that makes it OXPHOS

    • @Salam_1965
      @Salam_1965 8 місяців тому

      It is called Oxidation because of stripping the Electron from NADH and FADH2. It is called Phosphorylation because of giving a Phosphorous to ADP.

  • @danielacampos4987
    @danielacampos4987 9 місяців тому

    Flawless! Loved the fact that you emphasized high yield concepts.

  • @shav2004
    @shav2004 2 роки тому

    Now this is what we called an explanation. I got it perfectly! Thanks a lot ❤

  • @abdulg4360
    @abdulg4360 4 роки тому +22

    It's very high yield to know,Allegedly.

  • @maxbilo6191
    @maxbilo6191 2 роки тому +3

    01:43 Goal of Electron Transport Chain
    12:46. Electron Transport Chain inhibitors
    13:42. ATP Yield

  • @maryscales6648
    @maryscales6648 2 роки тому

    Thank you, Thank you, Thank you!!! You have helped me pass my exam for nursing, maybe even get an A!!! Can’t thank you enough!

  • @Frida2024
    @Frida2024 3 роки тому +1

    Thank you! Prepping for the MCAT and I felt so so so so lost.... I'll be sharing this video!

  • @raissachiri1302
    @raissachiri1302 Рік тому +3

    That moment when you realize that the Electron transport chain is called like that bc IT TRANSPORTS basically the same ELECTRONS from complex to complex 😅 I know this is so basic but looking at this animation everything just made sense ❤ thank you!

  • @GoldynChyld238
    @GoldynChyld238 4 роки тому +3

    Aspirin Toxicity will also cause an uncoupling effect (it's responsible for the fever).

    • @GoldynChyld238
      @GoldynChyld238 4 роки тому +1

      Also worth mentioning Brown Fat (Thermogenin)

    • @chadaitken5476
      @chadaitken5476 4 роки тому +1

      This is the type of information on top of this video that I’m looking for. We want more info on top of this process. Thx

  • @meccarasheed3018
    @meccarasheed3018 3 роки тому +2

    This legit has saved myself with my advanced two nutrition class! I sincerely appreciate the visual representation!

  • @kowsalyas1752
    @kowsalyas1752 3 роки тому

    Yeah it's too clear .... I watched many lectures and UA-cam videos but only this video gave a clear picture about oxidative phosphorylation and electron transport chain...... thank you soo much

  • @damaster7276
    @damaster7276 4 роки тому +24

    So if we figure out how to reverse the ETC i can turn water into Oxygen. So basically my dreams of becoming a fish isnt that far fetched? lul

    • @sauravsumughan
      @sauravsumughan 3 роки тому +11

      Using energy to make oxygen so that you can use oxygen to make energy. Give this man a Nobel prize 😂😂

  • @ufatemav4509
    @ufatemav4509 4 роки тому +3

    h i g h y i e l d

  • @sugarfreak14
    @sugarfreak14 3 роки тому +1

    Thank you soooo much! I have an exam this morning and I couldn’t find anything to help me understand it fully but your video has! Thank you so much!