APOPTOSIS PART 1: Definition, Causes & Mechanism/Pathways

A series of video tutorials discussing the topics for undergraduates in Pathology
In this 1st part of Apoptosis tutorial , i have discussed Definition, Causes & Mechanism/Pathways
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• Definition of apoptosis
• Causes /conditions where apoptosis is seen
• Understand the mechanism of apoptosis
• Extrinsic pathway
• Intrinsic pathway
A pathway of cell death
Induced
By a tightly regulated suicide program
Found in 1972 John Kerr, Andrew H. Wyllie & Alastair Currie
Greek - mean "falling off" (like leaves falling from a tree)
Also referred to as programmed cell death
PHYSIOLOGICAL CONDITIONS
Embryogenesis
Involution of hormone dependent tissues
Menstruation, menopause, weaning
Loss of cells in proliferating cell populations
Bone marrow, thymus
Removal of self reactive lymphocytes
Death of inflammatory cells after their functions are over
PATHOLOGICAL CONDITIONS
Injured cells which cant be repaired
• DNA damage
• Misfolded protein accumulation
• Viral infections
• Duct obstructions
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
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[@Kyle0714]

I wish you taught pathology at my school. I had no idea that Caspase was a mashup of 3 different things, crazy!

[@TheSK1199]

Thank you sir. Reading robbins is so easy after watching your video

[@hritvikjain__3594]

I generally don’t comment of the educational videos on YT. But if I’m commenting, the shit is really awesome. I was so scared of Apoptosis, that i even decided to skip it for my exams. But after watching this video, the mechanism of apoptosis is very clear to me now.
Thank you sir 🙏🏻.

[@ilovepathologyVijayPatho]

Hritvik Jain thanks 😊 glad you liked it 😊

[@92soofiyanoushad8]

Sir, this vedio is really an exam capsule 😍.thank you

[@selvambigaig6541]

Awesome. Keep up the great work. A real boon for students.

[@criticaltruth5184]

awesome videos. love the details of the caspaces and the IAP family

[@kapilnath4059]

Precise Explanation sir . Thank you very much ..

[@17anandp86]

Such a wonderful class
So easy to grasp the topic after hearing your class sir

[@josetrujillo738]

I enjoy your lectures. I appreciate your very great ability to teach

[@sindynurafia4063]

im coming from country who dont use english as daily basis, so its difficult for me to listen and understanding something in english . you should turn on the subtitle, it would make me easier to understand. at least i can read it.

[@doc599]

Ahhh.....such a detailed yet precised explanation

[@rianacaeiro8711]

Very well explained, thankyou so much.

[@narendrachaudhary609]

Wow..love it❣️
Such a good explanation in short time

[@Artsylove4]

Thank you so so much sir for this tutorial ..❣️

[@arvaoz6799]

Was very helpful! Thank you so much! :)

[@koolshakthi1985]

This is excellent. Thank you!

[@pakapapita3104]

Thank you so much sir, I read Robbins only after watching your videos.

[@Artsylove4]

Me too

[@venkateshwarlugangishetty8853]

Wowww,simply super 👏👏

[@abhijityeole8462]

Awesome. Thank you soo much sir!

[@piyumidissanayake6244]

great sir,thank you

[@anaskp4667]

Love your classes

[@lpangmeiphom1324]

Cleared my basic concept 🤘tq sir

[@DrDmitrii]

Thank you brother!

[@kidzstories2412]

Thank you sir easiest slide & explanations to follow 🙏🙏🙏

[@nandinimoorthy3163]

super great job

[@shameenabanu1143]

Thank u so much sir .....it is so. Much clear explanation
....

[@HassanAli-zq3ml]

simple and clear

[@TheSandeepkumar1991]

Thanks you sir..

[@anushabachchu1273]

Simple and super sir!

[@samyu7925]

please make more videos like these sir🙏🙏🙏

[@ananyagupta9730]

Thank you so much. I have much better understanding

[@janakignanan7793]

Thanks a lot :) This helped me alot for my degree :)

[@tahiransari3917]

Very helpful sir

[@harshaharidas4786]

Thankuu very muchh sir
Very helpful👍👍

[@puneetsharma1134]

thankew sir.

[@50divyaramesh77]

Excellent video which explains each and every point clearly😊please do more videos in all topics as possible.

[@polokocollen7072]

Thank you.

[@Baharaakbari]

Amazing thank u so much ☺️

[@phoolphool396]

Really helpful video

[@JoohiMahesh]

Thank u sir for this lecture

[@SMM-qp9ig]

Gorgeous way

[@13.tarunchandwani51]

Thank you sir

[@shitalsurushe7496]

Thank you

[@benazirnowshath9002]

Could anyone give explanation more than this for apoptosis?! Really awesome sir🙌

[@shashishah7887]

could you please elaborate how the molecules on inner side of cell membrane got to be on the outside?because that's what caused phagocytosis...

[@suman-by7gt]

thanks so much

[@shahnasshajahan529]

Thank you 💟😊

[@user-qk4hn5ce9x]

thank U 👍

[@rutujamohite4890]

A Great Thank you

[@sebastianm.6875]

amazing

[@nagamanigv8225]

Thank you sir nyc teach

[@21aparnamadhusoodanan94]

Thankyou sir❤️

[@padmamahindravada]

Excellent video. very clear. Thank you sir

[@ilovepathologyVijayPatho]

Glad it was helpful!

[@fatahabdinur5383]

ty bro

[@sabreenmodak7746]

Can i please know the name of the book that you've referred here?

[@fatahabdinur5383]

saved my life

[@zainabalradi2306]

you are a god

[@JackT13]

I like the video but I thought apoptosomes were heptamers (7 sub-units)?

[@abhi-wi2mj]

Explanation was very nice.

[@ilovepathologyVijayPatho]

Glad you liked it

[@laurachueire4625]

perfect

[@vaisshnavi1257]

Smooth like butter 🧈🤌🫶💥💕💜💜💜💜💜💜💜💜

[@ilovepathologyVijayPatho]

Thank you 😊

[@Daawonuurka]

Thank you From Somalia 🤒🥲

[@sainiksefteri7832]

how apoptotic factors are occurred and where? Due to WHAT?

[@ikramshehzad6936]

Thanks 😊 sir which one book you following?? For better understanding of pathology

[@doc599]

Robbins pathology

[@hibakaleed387]

Please can I get this file I need to study it ?

[@Rohit-fy4kl]

Sir which book you are following

[@chagalamukamorris4744]

Chagalamuka used this ❤

[@user-iw9ps3oj9l]

❤❤❤

[@anaskp4667]

Could you please share the ppt

[@rosejasmine4214]

Very useful👍👍👍 thank you

[@user-wh1ev7gq6o]

H7

[@ursgp7]

❤

[@anaskp4667]

Sir

[@tejasgadekar6153]

👍

[@pubsmedworld101]

Best teacher for pathology

[@ilovepathologyVijayPatho]

Thank you 😊

[@jaydeepchauhan7712]

sir this is the fantastic explanation, sir...can you please make a telegram channel for multiple choice questions practice,so that we can apply the knowledge of pathology

[@ilovepathologyVijayPatho]

Thanks so much :-) I think there is already a telegram channel for MCQs practice.. you can join that

[@jaydeepchauhan7712]

@@ilovepathologyVijayPatho can you mention the name ....plzz sir

[@ilovepathologyVijayPatho]

jaydeep chauhan "pathology UG Quiz😊"

[@saloniparekh8419]

This is so simple and easy to understand.R u from india?

[@ilovepathologyVijayPatho]

sanjana parekh thanks 😊 and Yes!

[@imanehdjb402]

S'il vous plaît, quelqu'un me traduit les causes de l'apoptose en français

[@pavanjadhav5116]

Thank you sir....still I hate patho😭

[@ilovepathologyVijayPatho]

Wish I could make it interesting for you 😊

[@pheonixheart5534]

💜💜💜🏌️‍♀️

[@nativetexan6628]

I'm sure your video is very good, but I couldn't understand the words you were saying. I got a few words but your accent is so heavy that I just couldn't get it. I am so sorry.

[@ourvinesshahzad3931]

Thank you sir

[@abhi-wi2mj]

Thank you.

[@ilovepathologyVijayPatho]

You're welcome!

[@rikkigupta9546]

Thanks alot sir

[@ilovepathologyVijayPatho]

Most welcome