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Pathophysiology of Gastroesophageal Reflux Disease (GERD)
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- Опубліковано 16 лип 2012
- Physiology lecture on gastroesophageal reflux disease including causes based on the anatomy of the gastroesophageal junction.
My husband has Barrett's Esophagus, diagnosed in 2020. He is 75 (as of 3-20-24), had Parkinson's Disease diagnosed when he was 61. He is very thin & has had GERD for the past 31 years. Since 2021, he has been undergoing radial frequency ablation, cryoablation, dilations, biopsies, and a 4.5 hour endoscopic submucosal dissection of the esophagus in May of 2023. Per your video my husband does not have 2 of the 3 conditions that lead to GERD. He is not morbidly obese nor does he eat fatty meals. He does like to drink a diet ginger beer a couple times a week. So I guess he has a hypotonic circular muscle at the lower esophageal sphincter that has caused his Barrett's esophagus. He also has diastasis recti, just learned of this when he had bilateral hernia repair done in Jan. of 2024. Wondering if diastasis recti contributes to a thinning of the muscle tissue around the stomach or widening of the Angle of HIS even in a thin person? (He is 5 ft 8 inches & weighs 140 pounds.) Very interesting to learn that enzymes not acid is what causes Barrett's Esophagus and not the acid because the Pantoprazole that he takes does not stop reflux, it just reduces symptoms of acid in the esophagus.
Such a great explanation!!! Lights went off in a big way! Thank you for such a clear presentation.
You are absolutely awesome... teaching is an art and you are a master. As a nursing student, the more you can include signs and symptoms to watch for and nursing interventions all the better for me!
I learned some new things toward the end. You can get barretts or make your Barretts worse even if you are no longer burning yourself with stomach acid because the cold reflux is still bad for you. Thanks Andrew. I'll mention it to my doctor.
Also, I don't know if you know about the Golden Rest beds. I just bought an adjustable bed at Sears but I bought the wrong kind. It looks to me like the Golden Rest has the right idea because you can roll over and sleep on your side or stomach without bending your back the wrong way and still maintaining a good angle to prevent stomach contents from getting up in the esophagus.
The bed I just bought does the same thing most adjustable beds do. It lifts your feet or your back so if you lay on your back all night your GERD will be controlled. Trouble is I hate laying on my back all the time and I have a lot of trouble getting to sleep in that position.
I really enjoy all of your videos. You are an excellent teacher!
Very good and helpful. I understand more clearly the cause and affects of this disease, rather poor eating habits. Thank you.
Thank you!
Thank you so much for this. As a medical student, I felt this was very informative for the subject and well displayed and explained.
I was a sufferer of heartburn, chest pain and acid reflux but right after following this heartburn treatment HeartBurnCure9.blogspot.kr
, all those issues were fully gone. I also cured my constant fatigue and rushes due to it. I really feel great and at the peak of my health.?
You're welcome and thanks for watching!
Loving all your patho videos! Thank you so much! Very useful and concrete!
Keep watching, we appreciate the support!
Awesome video! You explained it very simply. I am a paramedic student, so this video is completely irrelevant to me as far as testing is concerned, but I'm very interested in the physiology behind the conditions, and I am still considering going to med school after paramedic. I'm going to start watching your other videos too. Thank you!
Keep watching, we appreciate the support!
Great Video but you said the LES becomes hypotensive. Is that supposed to be hypotonic? Just looking for clarification. Thank you.
i am getting cough some times. and heat sensation in my stomach and reflux gases (since 2 years) when i eat . and my stomach un able to digest any kind of food for atleaast 6-7 hours. what might be the probable reason for un digestion. weather i have to consult a gastroenterologist? thanks in advance
thanx for informative vids.keep them coming on more systems.god bless u..
Keep watching, we appreciate the support!
Hi there, great video! I'm currently studying naturopathic medicine and learning the pathophysiology of the gut. I understand there is a place and time for medication- but with GERD (which so many of the population present with), I can't believe the dependence on acid blockers which aren't even treating the cause! Do you know if med schools are educating more about the impact of diet on at least this condition? Also, have you heard of states where too low of acid can cause relaxation of LES?
Of course medical schools talk about the underlying causes of GERD. The reason so many people are on medication is because 1) they need something to treat their symptoms, and 2) there are potentially very serious complications of GERD which need to be managed. As a naturopath, you will be treating people who are motivated to live a healthy life; they will be coming to you primed to make healthier changes. But, there are many people out there who either aren't motivated, haven't had someone directly tell them they need to lose weight, or (in the vast majority of cases) there are other factors which make achieving and maintaining a healthy weight very difficult (societal, mental, metabolic, medical etc). Health can be a very complex issue and I encourage you to think broadly and critically about these issues. Welcome to the health system
Why does GERD present as LPR in some people? It is my understanding that LPR is caused by aerosolized pepsin getting into airways, including nose, throat, and larynx. What is the mechanism that causes this to happen, other than a leaky LES?
Can you stress more on treatment modalities , protocols to be followed other drugs used like acotiamide.
Indications for surgery.
Also other symptoms like hoarseness of voice
As this is had become a common disease
Hi there! Dr. Wolf and the rest of the team here at Health Ed Solutions will be releasing new content weekly starting very soon :)
great movie
Hey Andrew, Great videos.
If there is less erosion due to PPI's or H2 blockers wouldn't it mean it would decrease the risk of barret's, because barret's is due to erosion?
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
Informative❤
Glad you think so!
always amazing. thank you sir
Then how do you cure GERD/chronic acid reflux? Is there an actual "Permanent Cure" that works or just symptom treatments for life? I developed weaked LES after chronic overating. So, after I eat, a lot of food just comes out of my mouth effortlessly. What should I do to cure this?
Dan Jang, how are you now?
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
Hello Andrew,
I had a LINX magnetic device placed a week ago with slight improvements. Any thoughts? Ron
Thanks for watching Ron!
So what actually can be done for this? How can it actually be treated rather than falsely treated?
Thanks for your question. We have passed it along to the Health Ed Solutions medical review board. Thanks for watching!
Very enlightening...so what is the alternative treatment!since antacids and ppi's just relieve the pain?
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
thank you :) i'm a medical student and that was quite a nice introduction!
a few questions though..
1- what's the program (and hardware) you use to do these lectures?
2- what are your resources?
Thanks for your inquiry. The whiteboard lessons are created using a Wacom Bamboo tablet. Thanks for watching!
Nice introduction here. if there will be reflux of acids this will give them heartburn right? why is it PPI and H2 blocker can't fully treat GERD what is the best medicine for this sir?
Thanks for your question Erick. We have passed it along to the Health Ed Solutions medical review board. Thanks for watching!
Thank u very much... I'm really shocked by the information that "reducing the amount of acidity in the stomach will not reduce the frequency of parrot esophagus/cancer"!!!
So, what do u advice me to do instead of just taking antacids?... I started taking them 4 months ago and that is when I started feeling acidity. However, I had started feeling the sour taste in my mouth some 7 YEARS ago.(gradually)
Do u advice me to go for surgery? How much is it likely to be successful?
Did u go for surgery? Or you managed by any other method. Pl tell
Dr Wolf,,,, No more videos.??? Your last from 2012.? I would like to ask about the stomach enzymes.??
Hi there! Dr. Wolf and the rest of the team here at Health Ed Solutions will be releasing new content weekly starting very soon :)
@@HealthEdSolutions Thanks.! I'm ready... Looking forward...
So,,, I'm waiting...
thanks a lot
You're welcome and thanks for watching!
sir my age is 35 years and iam suffering from stomach related issues from my child hood i quit my all works and sit simply due to this health conditions. my endoscopy results is Gastritics i am dying from this problem. please give me some solution.
Same problem suffering from gerd....i die here...because irritating my life
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
could you talk about the surgical treatment and its indications ?
Hi there! Dr. Wolf and the rest of the team here at Health Ed Solutions will be releasing new content weekly starting very soon :)
Is it possible to change the angle of his surgically? to correct reflux?
fundoplication
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
Hi Andrew Wolf
Thank you for a very fin video. Do you have any references for the mechanisms you describe about the reduction of the angle of Hiss?
+Andrew Wolf
Hi Andrew thank you very much for your repIy. I will look into those references.
Thanks for the feedback! We will be rolling out new lessons soon. Thanks for watching.
Thanks ☺
Thanks for watching! More to come:)
Sir can i cure it completely plz answer me
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!
and by the way, I am a 32-year-old man diagnosed with Patulus GE Junction
👍👍👍
Put speed at 1.25.... you're welcome
Thanks for the feedback Bianca! We will work to speed things up in the future:)
Thankyou :) (y)
Thank you!