Going for MOHS on Wednesday - being the type of person I am, I like to completely understand my health issues (eg. in this case, what they found in my biopsy for BCC). Thank you!
Just want to point out your professional and academic excellency in this video - chapeau to that! Looking forward to some more great )video) material from you.
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Glad you liked it. You may find these other intro videos helpful. SCC and AK: ua-cam.com/video/y9OzN3-OlSU/v-deo.html. Nevus: ua-cam.com/video/jKZDqJez9jw/v-deo.html. Melanoma: ua-cam.com/video/8N0IZZpF8ts/v-deo.html. Also if you like my videos, check out my #dermpath Survival Guide book: bit.ly/2Te2haB
I have my BCC surgery on nose on 2-16. I'm a little scared, but not surprised since my grandmother and aunt died of skin cancer. My late dad had skin cancer too, but never had to have surgery like me. I think that's what scares me.
I’m sorry you are going through this and that you feel scared. Surgery can be a scary experience for anyone. There are many types of skin cancer, not all of them behave the same or are treated the same. the good news is that BCC has an excellent prognosis when treated correctly. Although it can grow back if it is not completely removed with negative margins, it is EXTREMELY rare for it to spread to other parts of the body (metastasize) or cause death. I diagnose multiple cases of BCC every day but I’ve only see 3 cases of metastatic BCC in my entire career! So try not to be too anxious about that. Did your grandmother and aunt have melanoma? That is the kind of skin cancer that is sometimes fatal and it is totally unrelated to BCC. Best wishes for successful surgery and quick healing for you!
@@JMGardnerMD Thank you for responding and your encouragement. I'm uncertain what kind of skin cancer my grandmother had. All my aunts, uncles, and parents have passed so I have nobody to ask. In addition, my aunt's daughter has passed so I cannot ask her either. I know my grandmother had a skin cancer above her eye and didn't have it looked at it in a timely matter. The cancer spread into her eye and she had to have her eye removed. Hopefully, it was melanoma for her and my aunt. I'm Irish so I know I'm more prone to skin cancers as well as my dad, grandmother, and aunt. I do have a wonderful dermatologist and hoping he can perform his magic on my nose without too much deformity. I've got to be strong and deal with it.
I have had 9 basal cell carcinomas removed only one with the light mohs incision no stitches just a little divot scoop no stitches needed the other eight needed a lot of stitches one basal cell I let go thinking it would a small divot scoop I let go but it was much worse the Dr said it looked like it was going on in center of my chest for over five years but it only started to get a scab and crack and bleed for less than a month before I went to get it removed That was so foolish he had to make what looked like the mark of zoro in the middle of my chest over 25 stitches to close the Z.lol since then I get checked every 6 months with no malignancies for 31/2 years then after 3 1/2 years I just had my 9th basal cell removed got about a 2 inch scar on my right neck by the clavicle it took about 7 or eight very close stitches but I really want to say I have been taking Nicotinamide 1000 mg a day 500 mg 2 x a day 1 500 mg before breakfast and another 500 mg pill after lunch and I have only had 1 basal cell in 3 1/2 years I feel the Nicotinamide has helped keeping away the extra malignant basal cells I mostly just get pre -cancer cells that I have frozen off and that's a lot better than surgery last year the Dermatologist prescribed my with 5-fluorouracil (5-FU) but I only put the cream on my upper chest and shoulders front and back that stuff made me look like a went through a fire but I did not put enough on my neck area and that is where my last basal cell was The 5-fluorouracil (5-FU) is a very unsightly treatment and causes a lot of discomfort but the Dr Said it removed many furture pre cancers and cancers from forming .So I will keep taking the Nicotinamide and keep getting 6 month check ups and have these basal cells removed ASAP from now on good luck to all those who are suffering with life long skin cancers . But the sooner they are removed the smaller the scar . I learned the hard way you can say I got fooled by the small Mohs procedure I had the first time best of luck to all your friend Zoro lol
3 years ago I had basal cell carcinoma on my nose. Now I have another spot close to where it was before. She took a biopsy and it's basal cell carcinoma on my nose again. I go 10/20/24 for her to buff it out/ smooth it out. No stitches last time. 🙏🙏
amazing video indeed. looking forward to a video about adnexal tumors and how to distinguish trichoepithelioma vs BCC! Thanks a lot. Great teacher and mentor Dr. Gardner!
Thanks! check out our skin adnexal tumors made simple paper in @ArchivesPath: www.archivesofpathology.org/doi/pdf/10.5858/arpa.2018-0189-RA. Also discuss this in my new Dermpath survival guide book coming out this month: bit.ly/2Te2haB
Love your videos Dr. Jerad. Do you know any other youtube pathology channel like yours? Really like the way you teach and your expertise on the subject, thank you for sharing it. I'm an argentinian med student that appreciate your work.
"Dr. John Campbell" (retired, PhD in nursing education) has a series on body parts. (Edit: "Anatomy", that's the word. Sorry, I just turned 70 and my brain has decided to retire too.) I was an elementary school librarian. I dropped by because I'm interested in everything -- which is fairly common amongst librarians. He's become somewhat famous for his work on explaining and staying up to date on Covid, including a willingness to state he was previously wrong when new research comes out, and several snarky vids on gov't response to Covid. Shortly after he started, conspiracy theorists and various trolls showed up, but he's won them over by his meticulous work. In fact, he was onto Covid before almost anyone because two doctors in China (who had studied his vids) emailed him about a dangerous new disease, info of which was being suppressed by the gov't. (Emails that added "don't use our names" which he never has. His other videos are full of rave reviews world wide from nursing and medical students.
While Stage IV (Metastatic) Melenoma is the ultimate francoanaplasia according to medical consensus, a Basal Cell Carcinoma (BCC) is fairly underrated as such is primordial cellular malignancy, the Stem Cells of the skin in my personal reckoning. Furthermore, such is the anaplasia that it is infiltrative while undergoing typical cellular differentiation deep into the dermis and hypodermis even. The metastatic, late- staging of a basal cell malignancy should be when it has infiltrated while forming keratosis (Basosquamous Carcinoma Mimic) and mimicing a Squamous Cell Carcinoma (SCC) as if it was under normal maturation morphology. Otherwise, I suspect a most clear and serious neoplasia is systematically being mal-appraised for what it cytologically is, a cellular lesion of serious and fatal genetic Aetiology....lol
Thank you. It's my pleasure. You are in luck...I'm working on an adnexal tumor review article for Archives of Pathology & Laboratory Medicine. I plan to create some videos to go along with the paper. Hope to have these out in the next few months.
Thank you for the wonderful video Dr. Gardner. What is your experience with BCC in the pediatric group? Have you seen such cases in children? I have such a case right now, a superficial BCC in a 14yo boy. I haven't checked with the treating clinician yet to see if there are any genetic syndromes present, but the location is strange to me, as it is on the trunk.
Hi Dr.Gardner! My friend was recently diagnosed with basal cell adenocarcinoma parotid gland. She had biopsy done by her dermatologist which slowed basal cell adenocarcinoma... she has not had parotidectomy yet...since the biopsy her tumor has shrunk by 60%!!!!!! It is still shrinking! Is it normal for basal cell adenocarcinoma tumor to be shrinking after biopsy without any surgery or radiation? Is it possible that she was misdiagnosed ?
I'm sorry, I don't know much about basal cell adenocarcinoma as it is a salivary gland tumor. It is different than basal cell carcinoma of the skin. I'm a skin pathologist, so I don't handle many cases of salivary gland tumors. Best wishes for health and healing for your friend and peace for you both.
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology). Sample pathology report templates for BCC: kikoxp.com/posts/5093 (includes examples of how I sign out various types of BCC along with a lot of commentary).
Awesome as always ! thank you. At 7:15, the peripheral inked margin is positive? in the superficial BCC. If yes, does that have to be mentioned in the report? TIA.
I prefer not to report “margins” on shave biopsy of BCC and SCC as they are not reliable. A significant subset of cases with apparently negative margins are actually positive. But I will report them if requested by a dermatologist as a courtesy. Here’s our paper on this topic: www.archivesofpathology.org/doi/full/10.5858/arpa.2015-0313-OA
Thanks for the great series of videos, they're extremely helpful! What is the main difference in differentiating between cystic basal cell carcinoma and adenoid basal cell carcinoma? I'm looking at the image in Rapini's Practical Dermatopathology (2005) and I'm not seeing a stark difference between your example of adenoid BCC (26:00) and Rapini's example of cystic basal cell carcinoma. Some clarification would be greatly appreciated, keep up the great work!
Thank you! Adenoid cystic carcinoma has very sharply punched out perfectly round spaces, whereas in adenoid BCC they are usually much more irregular. Sometimes you can find areas that at high power look very similar between the two tumors, but from low power they are easy to tell apart with practice. Adenoid BCC usually has other classic BCC features like mucin filled cleft artifact. Primary cutaneous adenoid cystic carcinoma is usually indolent (different from its salivary gland counterpart), much like BCC.
Yes I’m working on adding English subtitles to all of my videos. My medical students have been volunteering to help with this but it takes a lot of time so it’s slow going. BCC is one of the next ones coming up on the list so hopefully it will have subtitles soon. Also my videos are open for public contributions for subtitles via UA-cam. So if you have friends who are Portuguese speakers who want to listen to the video and transcribe it into Portuguese they can submit that through UA-cam and it will let me approve it to add to the video.
They are slow growing tumors. I often see several weeks or even a month or longer between date of original biopsy and date of excision surgery to fully remove the tumor.
Please go see your dermatologist for evaluation. It might be something benign, but it’s always best to get a new or changing skin lesion checked by a dermatologist to be sure. Best wishes for good health!
Thank you for a wonderful video and helpful knowledge! By the way, Dr. Jared, can I ask a question: can we use p40 and p63 IHC to differentiate the BCCs with granular cells or clear cells with other metastatic carcinoma?
I don’t know. I’ve never heard of checkpoint inhibitors being used for BCC. For superficial BCC, topical imiquimod is sometimes used which is kind of like a form of immunotherapy I guess. It enhances immmne response towards tumor locally. For advanced or metastatic BCC, vismodegib hedgehog pathway inhibitor may be used.
Thank you for letting me know they were missing. I added them before but for some reason they didn’t save. I’ll upload them again. For now, here is the transcript. www.dropbox.com/s/k51c4by8ykorvyh/BASAL%20CELL%20CARCINOMA%20-%20TRANSCRIPT%20-%20%20%20%20%20PROJECT%20-%201%20Mitul%20Modi.docx?dl=0
Dermatologists Gardner and Singh together will turn neoplasia into what it was really intended by nature: Make cellular geneneration infinate and thus making mankind ETERNAL....lol
Thank you Dr. Gardner for the great educational videos.
Basal Cell Carcinoma
Introduction: 0:00 - 1:02
Classic Features of Basal Cell Carcinoma: 1:03 - 3:18
Basal Cell Stroma: 4:55 - 6:07
Patterns of Basal Cell Carcinoma: 3:19 - 36:48
Nodular - BCC 3:35 - 4:04 and 21:43 - 22:40
Superficial - BCC: 6:08 - 7:46
Basaloid Squamous Cell Carcinoma: 7:48 - 9:25 and 26:51 - 29:14
Nodular and Superficial - BCC: 11:00 - 12:40
Infiltrative - BCC: 12:40 - 21:38
Pigmented - BCC: 22:41 - 24:48
Adenoid - BCC: 24:52 - 26:50
Fibroepithelioma of Pinkus type - BCC: 29:20 - 31:20
Granular Cell variant - BCC: 32:52 - 34:10
Clear Cell variant - BCC: 34:15 - 34:52
Amyloid deposition in BCC: 34:56 - 35:41
Metastatic Melanoma in BCC: 35:43 - 36:48
Pleomorphism in BCC: 31:22 - 32:49
Seborrheic Keratosis in BCC: 36:50 - 37:34
Very proper duration of the video. The content is very very important for Pathologists.
Going for MOHS on Wednesday - being the type of person I am, I like to completely understand my health issues (eg. in this case, what they found in my biopsy for BCC). Thank you!
Glad this helped! Hope your Mohs procedure goes smoothly and you recover quickly.
Just want to point out your professional and academic excellency in this video - chapeau to that! Looking forward to some more great )video) material from you.
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Thank you from a Pathology resident on mat leave! This was super helpful! :)
I'm also on mat leave, find these very helpful for keeping in touch.
I have been going through your videos again and every time I see them I learn something new.
Very nice review of BCC. You are a gifted educator.
I wish youtube recommended this before 😭
Glad you liked it. You may find these other intro videos helpful. SCC and AK: ua-cam.com/video/y9OzN3-OlSU/v-deo.html. Nevus: ua-cam.com/video/jKZDqJez9jw/v-deo.html. Melanoma: ua-cam.com/video/8N0IZZpF8ts/v-deo.html. Also if you like my videos, check out my #dermpath Survival Guide book: bit.ly/2Te2haB
I have my BCC surgery on nose on 2-16. I'm a little scared, but not surprised since my grandmother and aunt died of skin cancer. My late dad had skin cancer too, but never had to have surgery like me. I think that's what scares me.
I’m sorry you are going through this and that you feel scared. Surgery can be a scary experience for anyone. There are many types of skin cancer, not all of them behave the same or are treated the same. the good news is that BCC has an excellent prognosis when treated correctly. Although it can grow back if it is not completely removed with negative margins, it is EXTREMELY rare for it to spread to other parts of the body (metastasize) or cause death. I diagnose multiple cases of BCC every day but I’ve only see 3 cases of metastatic BCC in my entire career! So try not to be too anxious about that. Did your grandmother and aunt have melanoma? That is the kind of skin cancer that is sometimes fatal and it is totally unrelated to BCC. Best wishes for successful surgery and quick healing for you!
@@JMGardnerMD Thank you for responding and your encouragement. I'm uncertain what kind of skin cancer my grandmother had. All my aunts, uncles, and parents have passed so I have nobody to ask. In addition, my aunt's daughter has passed so I cannot ask her either. I know my grandmother had a skin cancer above her eye and didn't have it looked at it in a timely matter. The cancer spread into her eye and she had to have her eye removed. Hopefully, it was melanoma for her and my aunt. I'm Irish so I know I'm more prone to skin cancers as well as my dad, grandmother, and aunt. I do have a wonderful dermatologist and hoping he can perform his magic on my nose without too much deformity. I've got to be strong and deal with it.
Perfect slides and great explanations. Thank you ..
Excellent video for beginners Dr Jerad , this has been so helpful !
I have had 9 basal cell carcinomas removed only one with the light mohs incision no stitches just a little divot scoop no stitches needed the other eight needed a lot of stitches one basal cell I let go thinking it would a small divot scoop I let go but it was much worse the Dr said it looked like it was going on in center of my chest for over five years but it only started to get a scab and crack and bleed for less than a month before I went to get it removed That was so foolish he had to make what looked like the mark of zoro in the middle of my chest over 25 stitches to close the Z.lol since then I get checked every 6 months with no malignancies for 31/2 years then after 3 1/2 years I just had my 9th basal cell removed got about a 2 inch scar on my right neck by the clavicle it took about 7 or eight very close stitches but I really want to say I have been taking Nicotinamide 1000 mg a day 500 mg 2 x a day 1 500 mg before breakfast and another 500 mg pill after lunch and I have only had 1 basal cell in 3 1/2 years I feel the Nicotinamide has helped keeping away the extra malignant basal cells I mostly just get pre -cancer cells that I have frozen off and that's a lot better than surgery last year the Dermatologist
prescribed my with 5-fluorouracil (5-FU) but I only put the cream on my upper chest and shoulders front and back that stuff made me look like a went through a fire but I did not put enough on my neck area and that is where my last basal cell was The 5-fluorouracil (5-FU) is a very unsightly treatment and causes a lot of discomfort but the Dr Said it removed many furture pre cancers and cancers from forming .So I will keep taking the Nicotinamide and keep getting 6 month check ups and have these basal cells removed ASAP from now on good luck to all those who are suffering with life long skin cancers . But the sooner they are removed the smaller the scar . I learned the hard way you can say I got fooled by the small Mohs procedure I had the first time best of luck to all your friend Zoro lol
Excellent as always 👍. Would you consider doing a video on distinguishing clear cells tumours of the skin in the future?
3 years ago I had basal cell carcinoma on my nose. Now I have another spot close to where it was before. She took a biopsy and it's basal cell carcinoma on my nose again. I go 10/20/24 for her to buff it out/ smooth it out. No stitches last time. 🙏🙏
Excellent demonstration sir
Good quality HPE images... good explanation.. Thank you sir...
Thank you very much. This was very interesting and relevant.
So informative. I had bcc removed by my dermatologist only a few weeks ago.
How are you doing today? Just found out today my fiancé has it
Very informative video on BCC... Wonderful indeed!!!
Excellent. Thank you very much, Sir
Thank you so much for this, I have an upcoming biopathology test and those videos have been more than helpful.
Excellent explanation
Wonderful presentation. Thank you very much from the skin cancer capital of the world!
Sydney?
"Middle East..."?
very nice! Thank you for your wonderful video.Expect more presentations.
amazing video indeed. looking forward to a video about adnexal tumors and how to distinguish trichoepithelioma vs BCC! Thanks a lot. Great teacher and mentor Dr. Gardner!
Thanks! check out our skin adnexal tumors made simple paper in @ArchivesPath: www.archivesofpathology.org/doi/pdf/10.5858/arpa.2018-0189-RA. Also discuss this in my new Dermpath survival guide book coming out this month: bit.ly/2Te2haB
It is an excellent presentation. Thanks.
Excellent review of basal cell carcinoma.
Excellent explanation .Thank you very much for such informative Vedios.
Thank you so much dear doctor
Simply superb 👏👏👏
very well explained 😊
Great review
Love your videos Dr. Jerad. Do you know any other youtube pathology channel like yours? Really like the way you teach and your expertise on the subject, thank you for sharing it. I'm an argentinian med student that appreciate your work.
Thanks! Try these: ua-cam.com/users/WashingtonDeceit. ua-cam.com/users/smurf3073
@@JMGardnerMD thank you Dr.!
"Dr. John Campbell" (retired, PhD in nursing education) has a series on body parts. (Edit: "Anatomy", that's the word. Sorry, I just turned 70 and my brain has decided to retire too.)
I was an elementary school librarian. I dropped by because I'm interested in everything -- which is fairly common amongst librarians.
He's become somewhat famous for his work on explaining and staying up to date on Covid, including a willingness to state he was previously wrong when new research comes out, and several snarky vids on gov't response to Covid.
Shortly after he started, conspiracy theorists and various trolls showed up, but he's won them over by his meticulous work.
In fact, he was onto Covid before almost anyone because two doctors in China (who had studied his vids) emailed him about a dangerous new disease, info of which was being suppressed by the gov't. (Emails that added "don't use our names" which he never has.
His other videos are full of rave reviews world wide from nursing and medical students.
you are amazing- dermatology resident
While Stage IV (Metastatic) Melenoma is the ultimate francoanaplasia according to medical consensus, a Basal Cell Carcinoma (BCC) is fairly underrated as such is primordial cellular malignancy, the Stem Cells of the skin in my personal reckoning. Furthermore, such is the anaplasia that it is infiltrative while undergoing typical cellular differentiation deep into the dermis and hypodermis even. The metastatic, late- staging of a basal cell malignancy should be when it has infiltrated while forming keratosis (Basosquamous Carcinoma Mimic) and mimicing a Squamous Cell Carcinoma (SCC) as if it was under normal maturation morphology. Otherwise, I suspect a most clear and serious neoplasia is systematically being mal-appraised for what it cytologically is, a cellular lesion of serious and fatal genetic Aetiology....lol
Awesome presentation! /swedish opthalmologist
Thank you! Great educational video!
awesome and comprehensive job...great presentation.
EXCELLENT TEACHING
Superb video, thank you professor
Thank you very much for the video, it was very helpful
You are a gift from god
Great great great lecture ever! Thank you so much!
Sir thank you for such wonderful videos. Can you post adnexal tumors videos?
Thank you. It's my pleasure. You are in luck...I'm working on an adnexal tumor review article for Archives of Pathology & Laboratory Medicine. I plan to create some videos to go along with the paper. Hope to have these out in the next few months.
very nice sir.. would like to see some vesicobulous hp slides
excellent
Thank you for the wonderful video Dr. Gardner. What is your experience with BCC in the pediatric group? Have you seen such cases in children? I have such a case right now, a superficial BCC in a 14yo boy. I haven't checked with the treating clinician yet to see if there are any genetic syndromes present, but the location is strange to me, as it is on the trunk.
Mihnea Derban yes I see BCC in kids occasionally, usually in association with Gorlin or other syndromes.
Multiple basal cell carcinoma - gorlin syndrome... probably present with various tumors and conditions
Awesome truly
Hi Dr.Gardner! My friend was recently diagnosed with basal cell adenocarcinoma parotid gland. She had biopsy done by her dermatologist which slowed basal cell adenocarcinoma... she has not had parotidectomy yet...since the biopsy her tumor has shrunk by 60%!!!!!! It is still shrinking! Is it normal for basal cell adenocarcinoma tumor to be shrinking after biopsy without any surgery or radiation? Is it possible that she was misdiagnosed ?
I'm sorry, I don't know much about basal cell adenocarcinoma as it is a salivary gland tumor. It is different than basal cell carcinoma of the skin. I'm a skin pathologist, so I don't handle many cases of salivary gland tumors. Best wishes for health and healing for your friend and peace for you both.
Sadly, I was not able to see my GP during lockdown. I had a growth that got very large. Just waiting for Mohs.
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology). Sample pathology report templates for BCC: kikoxp.com/posts/5093 (includes examples of how I sign out various types of BCC along with a lot of commentary).
Dear Prof. BCC with glandular differentiation, i don't know BCC has this subtype?
words are not enough to thank
Thank you so much Sir
Great presentation. Dr. Gardner: could you talk about squamous cell carcinoma and AK? Thanks
Yes, I am working on a video for that in the near future.
great one
Thank you for your informative video! Could you share your approach to coding when dealing with cases of mixed types of basal cell carcinoma?
Awesome as always ! thank you. At 7:15, the peripheral inked margin is positive? in the superficial BCC. If yes, does that have to be mentioned in the report? TIA.
I prefer not to report “margins” on shave biopsy of BCC and SCC as they are not reliable. A significant subset of cases with apparently negative margins are actually positive. But I will report them if requested by a dermatologist as a courtesy. Here’s our paper on this topic: www.archivesofpathology.org/doi/full/10.5858/arpa.2015-0313-OA
@@JMGardnerMD thank you!
Thanks for the great series of videos, they're extremely helpful!
What is the main difference in differentiating between cystic basal cell carcinoma and adenoid basal cell carcinoma?
I'm looking at the image in Rapini's Practical Dermatopathology (2005) and I'm not seeing a stark difference between your example of adenoid BCC (26:00) and Rapini's example of cystic basal cell carcinoma.
Some clarification would be greatly appreciated, keep up the great work!
Thank you! Adenoid cystic carcinoma has very sharply punched out perfectly round spaces, whereas in adenoid BCC they are usually much more irregular. Sometimes you can find areas that at high power look very similar between the two tumors, but from low power they are easy to tell apart with practice. Adenoid BCC usually has other classic BCC features like mucin filled cleft artifact. Primary cutaneous adenoid cystic carcinoma is usually indolent (different from its salivary gland counterpart), much like BCC.
Thank you Sir
I would like to give you a hug 😊🌸
Thank you sir Dr
What about mentioning Superficial Radiation Therapy as a treatment?
I m from Brazil. We study by your video. Could you please attach the subtitles in English?
Yes I’m working on adding English subtitles to all of my videos. My medical students have been volunteering to help with this but it takes a lot of time so it’s slow going. BCC is one of the next ones coming up on the list so hopefully it will have subtitles soon. Also my videos are open for public contributions for subtitles via UA-cam. So if you have friends who are Portuguese speakers who want to listen to the video and transcribe it into Portuguese they can submit that through UA-cam and it will let me approve it to add to the video.
Is it normal to wait a month before removing a basal cell skin cancer
They are slow growing tumors. I often see several weeks or even a month or longer between date of original biopsy and date of excision surgery to fully remove the tumor.
I just noticed the last few days a medium size pearly drying scaly new thing below my collarbone. . It wasn’t there when I got checked 1 year ago.
Please go see your dermatologist for evaluation. It might be something benign, but it’s always best to get a new or changing skin lesion checked by a dermatologist to be sure. Best wishes for good health!
No discussion as to whether BCC differentiates toward hair follicles?
Thank you for a wonderful video and helpful knowledge!
By the way, Dr. Jared, can I ask a question: can we use p40 and p63 IHC to differentiate the BCCs with granular cells or clear cells with other metastatic carcinoma?
P63 and p40 will stain BCC but is negative in most metastatic adenocarcinoma. So it can definitely help in that specific context
@@JMGardnerMD Thanks for your explanation! Really love your comprehensive educational and 5-minute videos!
Sir. Does immunotherapy provides a good response in basal cell carcinoma
I don’t know. I’ve never heard of checkpoint inhibitors being used for BCC. For superficial BCC, topical imiquimod is sometimes used which is kind of like a form of immunotherapy I guess. It enhances immmne response towards tumor locally. For advanced or metastatic BCC, vismodegib hedgehog pathway inhibitor may be used.
i want to know what happens in molecular level ..the mecanism i mean ... at the level of the chromosome?
Súper 🙌🏻🙌🏻🙌🏻🙌🏻
Hi do u have ovarian tumors HPE teaching?
sorry I do not. I don't practice ovarian tumor or other gyn pathology in my practice (aside from vulvar skin and soft tissue lesions)
Can you please help explain what borst jadassohn phenomenon
I think I talk about it in this IFK video kikoxp.com/posts/4379
Pleeeeeeease subtitles!!!!!!!
Thank you for letting me know they were missing. I added them before but for some reason they didn’t save. I’ll upload them again. For now, here is the transcript. www.dropbox.com/s/k51c4by8ykorvyh/BASAL%20CELL%20CARCINOMA%20-%20TRANSCRIPT%20-%20%20%20%20%20PROJECT%20-%201%20Mitul%20Modi.docx?dl=0
❤❤❤
👍👍
👍🏾👍🏾👍🏾👍🏾👍🏾❤️❤️
Dermatologists Gardner and Singh together will turn neoplasia into what it was really intended by nature: Make cellular geneneration infinate and thus making mankind ETERNAL....lol
Hall James Wilson Patricia Anderson Jason
Thank you sir