Can we find out our individual circadian rhythm timing? Like is each person different? Is there such a thing as a night owl that actually triggers their circadian rhythm at night time? 🥰🥰🥰
Yes, people do have their own circadian rhythms, but most fall within a certain range that aligns with the daytime/night time 24 hour period with our sleep/wake and light/dark patterns. HOWEVER, some people have misaligned circadian rhythms that are in sync with the standard daytime/night time light/dark pattern regarding their sleep/wake behaviors. These fall under an umbrella of various circadian rhythm disorders like advanced sleep phase disorder (falling asleep early and waking too early) "early worms", delayed sleep phase disorder (falling asleep very late and waking up later) "night owls", irregular circadian rhythm disorder, jet lag disorder, etc. Those require the person using sleep specialist provided regimens to shift or reset their circadian rhythm to the standard daylight/night time period. Advanced sleep phase and delayed sleep phase disorders aren't disorders per se, they're just outside of the norm. You're born with advanced sleep phase or delayed sleep phase conditions because those are your genetic internal clocks and it's just how you are. What do you mean night owl triggers their circadian rhythm at night? I think I can guess what you're asking. No, EVERYONE requires UV light to enter their eyes and pass through the SCN in the brain to activate the clock genes and initiate the circadian rhythm that we have-- even night owls. Night time has no UV light, unless someone is using a light therapy lamp at night to mimic daylight. You can roughly figure yours out by tracking when you fall asleep without any sleeping aides and when you naturally wake up without an alarm or any disturbances. Track it for a month. That should give a general idea. If you go to sleep around 10-11:30pm and wake around 6-7:30am...you're within a normal standard because you're going to bed when it's dark night and waking at around sunrise (as long as your job or school isn't effecting your sleep/wake periods--remember you're figuring out your natural sleep/wake patterns without any interference). If you naturally go to sleep before 10pm or wake up before 6am, then it could be advanced sleeping phase. If you naturally go to sleep after 12 am and wake up after 8am, then it may be delayed sleep phase. You'd HAVE to see a sleep specialist physician and have them evaluate it verify these concerns.
Not in the nucleus because they work as a dimer. Since BMAL1 and CLOCK are mainly located in the nucleus to fulfill the role as transcription factors, there is no evidence of BMAL1 or CLOCK to play a significant role in the cytoplasm. The knockout either Bmal1 or Clock leads to a disrupted circadian rhythm.
Very nice video, your sweet voice makes it even better. Love your voice . 😍😍
Great video surprised it doesn’t have more views
Can we find out our individual circadian rhythm timing? Like is each person different? Is there such a thing as a night owl that actually triggers their circadian rhythm at night time? 🥰🥰🥰
interesting question
Yes, people do have their own circadian rhythms, but most fall within a certain range that aligns with the daytime/night time 24 hour period with our sleep/wake and light/dark patterns. HOWEVER, some people have misaligned circadian rhythms that are in sync with the standard daytime/night time light/dark pattern regarding their sleep/wake behaviors. These fall under an umbrella of various circadian rhythm disorders like advanced sleep phase disorder (falling asleep early and waking too early) "early worms", delayed sleep phase disorder (falling asleep very late and waking up later) "night owls", irregular circadian rhythm disorder, jet lag disorder, etc. Those require the person using sleep specialist provided regimens to shift or reset their circadian rhythm to the standard daylight/night time period. Advanced sleep phase and delayed sleep phase disorders aren't disorders per se, they're just outside of the norm. You're born with advanced sleep phase or delayed sleep phase conditions because those are your genetic internal clocks and it's just how you are.
What do you mean night owl triggers their circadian rhythm at night? I think I can guess what you're asking.
No, EVERYONE requires UV light to enter their eyes and pass through the SCN in the brain to activate the clock genes and initiate the circadian rhythm that we have-- even night owls. Night time has no UV light, unless someone is using a light therapy lamp at night to mimic daylight.
You can roughly figure yours out by tracking when you fall asleep without any sleeping aides and when you naturally wake up without an alarm or any disturbances. Track it for a month. That should give a general idea. If you go to sleep around 10-11:30pm and wake around 6-7:30am...you're within a normal standard because you're going to bed when it's dark night and waking at around sunrise (as long as your job or school isn't effecting your sleep/wake periods--remember you're figuring out your natural sleep/wake patterns without any interference). If you naturally go to sleep before 10pm or wake up before 6am, then it could be advanced sleeping phase. If you naturally go to sleep after 12 am and wake up after 8am, then it may be delayed sleep phase. You'd HAVE to see a sleep specialist physician and have them evaluate it verify these concerns.
Thank you,
that helped a lot. ;)
Now my Thesis has become much easier xD
This video is gem ✨✨✨❤️❤️❤️, cant fathom the low view count
Does BMAL1 work without CLOCK in the nucleus or cytoplasm?
Not in the nucleus because they work as a dimer. Since BMAL1 and CLOCK are mainly located in the nucleus to fulfill the role as transcription factors, there is no evidence of BMAL1 or CLOCK to play a significant role in the cytoplasm. The knockout either Bmal1 or Clock leads to a disrupted circadian rhythm.
-