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parathyroid hormone in tamil[vitaminD-Sunlight ]MED TAMIL

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  • Опубліковано 6 сер 2024
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    0:00 intro
    0:53 synthesis of parathormone
    2:15 calcium regulation by parathormone
    4:26 -5:50 how sunlight gives vitamin D
    6:12 parathormone action on phosphate
    7:32 Applied physiology
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    PARATHORMONE
    „ INTRODUCTION
    People have four parathyroid organs, which are arranged on the back surface of upper and lower shafts of thyroid organ
    Every parathyroid organ is comprised of boss cells and oxyphil cells. Boss cells emit parathormone. Oxyphil cells are the declined boss cells and their capacity is known. Notwithstanding, these phones may discharge parathormone during obsessive condition called parathyroid adenoma. The quantity of oxyphil cells increments after pubescence.
    ACTIONS OF PARATHORMONE
    PTH assumes a significant part in keeping up blood calcium level. It additionally controls blood phosphate level.
    ACTIONS OF PARATHORMONE
    ON BLOOD CALCIUM LEVEL
    Essential activity of PTH is to keep up the bloodcalcium level inside the basic scope of 9 to 11 mg/dlThe blood calcium level must be kept up fundamentally in light of the fact that, it is vital for large numbers of the exercises in the body.
    1. On Bone
    Parathormone improves the resorption of calcium from the bones (osteoclastic movement) by following up on osteoblasts and osteoclasts of the bone.
    Fast stage
    Quick stage happens inside the space of minutes after the arrival of PTH from parathyroid organs. Following arriving at the bone, PTH gets joined with the receptors on the cell film of osteoblasts and osteocytes. The chemical receptor complex expands the penetrability of films of these cells for calcium particles. It speeds up the calcium siphon component, with the goal that calcium particles move out of these bone cells and enter the blood at a quicker rate. Moderate period of calcium resorption from bone is because of the actuation of osteoclasts by PTH. At the point when osteoclasts are initiated, a few substances like proteolytic catalysts, citrus extract and lactic corrosive are delivered from lysosomes of these cells. Every one of these substances overview or break down the natural lattice of the bone, delivering the calcium particles. The calcium particles gradually enter the blood.PTH expands calcium resorption frombone by animating the multiplication of osteoclasts too.
    2. On Kidney
    PTH builds the reabsorption of calcium from the renal tubules alongside magnesium particles and hydrogen particles. It builds calcium reabsorption principally from distal tangled tubule and proximal piece of gathering channel.
    3.Gi parcel
    Sun openness is the main normal wellspring of nutrient D. The body utilizes the nutrient to ingest the calcium it needs to construct and look after bones. Short eruptions of sun openness can as a rule permit your body to create all the nutrient D it needs for the afternoon.
    Activities OF PARATHORMONE
    ON BLOOD PHOSPHATE LEVEL
    PTH diminishes blood level of phosphate by expanding its urinary discharge. It additionally follows up on bone and GI plot.
    1. On Bone
    Alongside calcium resorption, PTH likewise expands phosphate ingestion from the bones.
    2. On Kidney
    Phosphaturic activity
    It is the impact of PTH by which phosphate is discharged through pee. PTH builds phosphate discharge by repressing reabsorption of phosphate from renal tubules. It acts basically on proximal tangled tubule.
    3. On Gastrointestinal Tract
    Parathormone builds the assimilation of phosphate from GI lot through calcitriol.
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