What are the medications available to treat low testosterone? | Peter Attia & Mohit Khera

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  • Опубліковано 30 чер 2023
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    Watch the full episode: • 260 ‒ Men’s Sexual Hea...
    This clip is from episode #260 of The Drive - Men's sexual health: Why it matters, what can go wrong, and how to fix it | Mohit Khera, M.D., M.B.A., M.P.H.
    In this episode, Peter is joined by Mohit Khera, M.D., M.B.A., M.P.H., a world-renowned urologist with expertise in sexual medicine and testosterone therapy
    In this clip, we discuss:
    - What are Clomid and Enclomifene and how do they work?
    - What is Klinefelter syndrome
    - How do medications for low testosterone effect fertility?
    --------
    About:
    The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
    Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
    Learn more: peterattiamd.com
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    Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use/
  • Наука та технологія

КОМЕНТАРІ • 249

  • @thomaslesperance6256
    @thomaslesperance6256 5 місяців тому +5

    Attia is the most elite doctor I’ve seen. Much respect.

  • @mipar134
    @mipar134 11 місяців тому +5

    I've heard of testosterone troches. I wonder if the rapid absorption via the sublingual route has similar pharmacokinetics to the nasal route he mentioned.

  • @peggyharper8193
    @peggyharper8193 11 місяців тому +1

    Thank you!!! My husband now has a Dr appt!!

  • @Billiehoyle
    @Billiehoyle 6 місяців тому +1

    this is very insightful about hcg

  • @oneboy153
    @oneboy153 11 місяців тому

    Very interesting

  • @bellakim9404
    @bellakim9404 11 місяців тому +9

    Compounded creams work great. Numbers went up substantially with regular use for me and my bf. Inner thighs for women and shoulder for men. I always apply right after a shower and rub in for 2 minutes with disposable gloves to prevent transfering.

    • @IlIKRATOSIlI
      @IlIKRATOSIlI 4 місяці тому

      Scrotum application is better for men.

  • @jrbisc99
    @jrbisc99 4 місяці тому

    I would love to hear your opinion on those with factor v Leiden and trt. I was basically told no by my local trt clinic when I told them I had it.

  • @superlyman
    @superlyman 6 місяців тому

    How do you spell Natesto? Trying to see how much it is and it’s side effects and what my doctor thinks

  • @mouhssinemaraji4379
    @mouhssinemaraji4379 2 місяці тому

    Amzing video, thanks a lot for the explanation. but would someone please help me find that study in which they used testosterone along side with hcg 500 to protect the spermatogenesis and testicular volume

  • @steve1085
    @steve1085 Рік тому +30

    Started on test injections but felt i had too much ups and downs. Androgel was great but if i did the under arm itd stain my clothes. The other forms just take too long to dry. Been on Clomid 8 years, daily, and havent seen any problems. Very predictable T, no loss of libido, and no elevated estrogen. For me it works.

    • @LC-lz6rw
      @LC-lz6rw 11 місяців тому

      Im almost 40 and mine is in the 160 range. ( got really sick after my pfisr booster shot) Where was your T-Level before and what is it now? Your age?

    • @steve1085
      @steve1085 11 місяців тому +4

      @@LC-lz6rw I started taking this in my mid 30s. I was around 200-300 then and am consistently between 800-900 now.
      With that said, I am now switching back to testosterone. Clomid costs have gone up dramatically and I can't justify spending an extra $1k a year for similar results

    • @steve1085
      @steve1085 8 місяців тому

      @@NomadicByNature I was at 50mg a day, but switched back to test. Clomid no longer has a generic manufacturer so it costs about $120 per month. Test is about $20. So I now do two 100mg shots per week. Hate having to pin myself that much, but it saves a bunch of money and that seems to level out the ups and downs
      200 per week will probably be higher for most men, but it's really the level I feel the most normal. Going back for blood work this week to see where that actually puts me on the numbers

    • @kbkesq
      @kbkesq 5 місяців тому

      You can also get compounded testosterone applied to scrotum but if you’re cruising along probably best to stick with it.

    • @kbkesq
      @kbkesq 5 місяців тому

      @@steve1085clomid helps you avoid testes shrinking and also estrogen spikes. You’ll be buying arimidex. If it’s working stick with it.

  • @glabalranter
    @glabalranter 6 місяців тому +1

    Does Natesto spray have as many side effects as the other modalities? It seems to be a safer option. Cheers.

  • @urwhatueat2170
    @urwhatueat2170 Рік тому +25

    Clomid was a scary experience for me. Over 10 days gradually became more exhausted. Then the “Vision abnormalities”… estrogen is part of the process by which we see color. My brain literally could not distinguish yellow. The yellow things in my field of vision would switch - yellow - orange - white. Very disorienting. Stopped that day. Back to normal in 3 days.

    • @AmritGrewal31
      @AmritGrewal31 11 місяців тому +4

      Lol, you make me want to try it, and I don't even need Clomid 😂

    • @123ChrisG
      @123ChrisG 9 місяців тому +1

      You need enclomiphene not Clomid. It has a shorter half life than Clomid so you can cycle it and after 2 days it will leave your system so you can get estrogen levels up and working. The side effects you experience are form the chronic low estrogenic activity.

    • @123ChrisG
      @123ChrisG 9 місяців тому +2

      Take 12.5-25mg every weekend and wednesday. Enclomiphene not clomid. This should do the trick.

    • @antondeklerkdrtony3d412
      @antondeklerkdrtony3d412 9 місяців тому

      @@123ChrisG from the blood workni have seen its better to smesh it 25mg to 50 then typer off and the testbstays high...

    • @kalonwright7906
      @kalonwright7906 7 місяців тому

      ​@@antondeklerkdrtony3d412do you mean taper off for good and T levels stay high? Or taper as part of cycling?

  • @guntherxtent
    @guntherxtent 8 місяців тому

    Any thoughts on Undecanoate? Seems to be the treatment of choice of many andrologists.

  • @oNe-TwO-fReE
    @oNe-TwO-fReE 2 місяці тому

    Thanks for this. I have learned a lot more. I was diagnosed with zero testosterone and very low cortisol levels. They performed an adrenal purge test and an MRI. Pituatary looked okay now on waiting list with the NHS for testosterone problem. I am still wondering why I have such low 9am cortisol levels. They told me they were 113 and should be a min of 300. It would seem they are ignoring the cortisol problem. Went from being highly energetic, dynamic athelete to have ZERO energy and zero motivavtion. Am considering going privte.

  • @olijfcadiz4231
    @olijfcadiz4231 6 місяців тому

    How will be the libido on hcg monotherapy for guys with low t levels?

  • @TheConpuentes
    @TheConpuentes 11 місяців тому +80

    My man Attia needs to let the guy speak. This is difficult to listen to the through interruption.

    • @JZGreengo
      @JZGreengo 10 місяців тому +3

      Chill, he’s asking questions

    • @Ray_Getard42069
      @Ray_Getard42069 10 місяців тому +3

      This is just how 200 IQ people chat, man. Nbd.

    • @jimmyt6334
      @jimmyt6334 9 місяців тому

      Throw him a slap and watch his IQ drop to nothing.

    • @db6220
      @db6220 8 місяців тому

      🤡🤡💩🤡

    • @pankinyek
      @pankinyek 5 місяців тому +3

      He does it almost with every guest.

  • @chayblay
    @chayblay 9 місяців тому +7

    I have a failed pituitary. Started on TRT, later added HCG and clomiphene for preservation reasons. Eventually switched to just HCG. Lost my insurance, stopped taking everything for a year and a half and was miserable. Just got onto Medicaid and blood work showed

    • @eoghankelly68
      @eoghankelly68 9 місяців тому

      How are you getting on with the nasal spray are you feeling any different

    • @chayblay
      @chayblay 9 місяців тому

      @@eoghankelly68 almost 2 weeks in, missing one full day of doses this last weekend. I’m feeling like I’m approaching normal but not quite there in terms of mood, motivation, vigor, mental health/resilience, muscle retention, etc., which aligns with the studied time it takes for any T supp to start working.
      Read the Results section of this paper for context:
      www.ncbi.nlm.nih.gov/pmc/articles/PMC3188848/
      Also, I should mention that I am not a fan of the nasal gel. It doesn’t prevent me from breathing, but it definitely clogs up my pathways somewhat and is not convenient at 3x a day.

    • @banana_1992
      @banana_1992 8 місяців тому

      Interesting, I would think that if your pituitary hormones are low at baseline (specifically LH) then you would be an ideal candidate for Clomiphene monotherapy. What made you choose Nattesto instead, and how are your levels resounding so far?

    • @mirapilates
      @mirapilates 7 місяців тому

      I'm curious what tests show pituitary issues. I've had a number of head injuries.

    • @banana_1992
      @banana_1992 7 місяців тому

      @@mirapilates most important pituitary hormone for testosterone is LH (luteinizing hormone), which is what stimulates the testes to produce testosterone. However be mindful that even if your LH is normal/high, the testes may simply be unresponsive (primary hypogonadism) resulting in low T regardless of how much upstream stimulation they are receiving from the brain pituitary gland. Look up “HPTA” for more info (hypothalamic-pituitary-testicular axis)

  • @michaelr1011
    @michaelr1011 8 місяців тому +7

    Two weeks on Clomid. Irritability is a real thing as I snapped at my wife a couple of times. I usually do a really good job of containing my temper/mood, however, these last two weeks have been challenging. The other area of concern for me is weight gain. I feel a little bit bloated while on this medication. Like things are moving slowly which has stalled my weight loss progress and making me feel lethargy. I'm focusing on upping my water intake and pushing through the sluggishness. I'm going to give this a full 8 weeks before I consider quitting, unless something major happens.

    • @judsonjman26
      @judsonjman26 8 місяців тому

      How are you feeling a week after this comment? Better? Worse?

    • @TheFoxyPlayer
      @TheFoxyPlayer 8 місяців тому

      Get on enclo, I’m on it now, nothing but upsides.

    • @jehaninfinity
      @jehaninfinity 7 місяців тому

      How you feeling now ? plz share

    • @DANTHETUBEMAN
      @DANTHETUBEMAN 7 місяців тому

      How are you doing on clomid now? 🤔

    • @TheRealJmal
      @TheRealJmal 7 місяців тому

      I had the same symptoms.

  • @eray9934
    @eray9934 6 місяців тому +3

    I would like to hear more about why he doesn't prescribe clomid anymore. I've had signs of low T all my life--I'm a skinny, unmuscular guy who can't grow a proper beard. I'm 46 and T was tested at 460, which is lower than average but doesn't qualify as hypogonadism. I don't to get on T and shut down the natural production I still have, so keeping my endogenous LH/T production sounds ideal.

    • @oooooooohhhYEAH
      @oooooooohhhYEAH 5 місяців тому +1

      clomid will increase your estrogen as well, and in most cases, only gives you an increase of T on paper, you may not feel the effects of a T boost like from TRT. It also has some nasty side effects, mainly with vision. Some men will get eye "floaters" that are permanent. The best option always is testosterone. It is always possible to jumpstart your natural production again although it wont be what it was and will require numerous other therapies like hcg, enclomiphine etc.

  • @visualpossibilities
    @visualpossibilities 26 днів тому

    They mentioned loss of libido with clomid, but they didn't mention if they same occurs with enclomiphene. I would like to know.

  • @dathill
    @dathill 11 місяців тому +4

    What about T dermal patches used by the likes of Bryan Johnson?

  • @Mediagix
    @Mediagix 5 місяців тому

    what about estrogen on hcg?

  • @alexanderohanlon8825
    @alexanderohanlon8825 7 місяців тому +18

    No one should be using this stuff, unless they have damaged testicals... Or at least until you've done the basics.
    1) reduced body fat to12-15%
    2) corrected metabolic dysfunction.
    3) optimised sleep wake cycles.
    4) preform strenuous activity for 30-45min per day.
    5) get stress in check.
    6) cut out all hormon dysrupting chemicals.
    7) do manly shit with the lads have an adventure.
    All of these sound difficult but they're just a case of over riding that bullshit voice in your head that moans and tricks you.

    • @Johny-tb8mg
      @Johny-tb8mg 5 місяців тому +2

      i agree and disagree at the same time, yes you should be living healthy like you described but even with all that you can still have low T, for example i did most of the things you mentioned and after 7 months from 304 ng/dL total T i raised it to a mediocre 384ng/dL so there is not way to naturally boost T by 2-3X, it requires medical help, and enclomiphene seems the best option 3 times per week

  • @nickdipietro7797
    @nickdipietro7797 11 місяців тому +8

    We’ve been using the same testosterone medications for over 60 years 😞

    • @N-xi2zh
      @N-xi2zh 6 місяців тому

      yes. steroids have research.. sarms newer, with less. and yeah same meds. ADHD med same even longer but they work well for ppl who need them. Anavar,. test e, and hcg seem safe and good. CREAMS for test and dht may be even better for many.

  • @fisherman_of_navarone
    @fisherman_of_navarone 3 місяці тому +4

    Peter you have to let your guest finish his points. We know you are intelligent. Allowing your guest to come across as intelligent does not reduce how you appear to your listeners.

  • @tracewaybos
    @tracewaybos 11 місяців тому +8

    Would love to see studies on extremely low dose HCG. I took 20mg EOD and my test levels skyrocketed. Started losing hair like crazy...

    • @antondeklerkdrtony3d412
      @antondeklerkdrtony3d412 11 місяців тому

      Hcg isn't a permanent fix it mimicks lh so when u stop it your brain doesn't make lh its a negative feed back like taking steroids now if you are on steroids it's nice to prime testees with it then a course hcg only after course of serms

    • @scal7122
      @scal7122 3 місяці тому

      Hcg raises testosterone?

    • @tracewaybos
      @tracewaybos 3 місяці тому

      @@scal7122 Google is your friend :)

    • @Peterdoran33
      @Peterdoran33 2 місяці тому

      HCG increases natural testosterone. It’s measured in IU’s

  • @vince4804
    @vince4804 Рік тому +3

    Is the part about tipping over a bottle of hcg and destroying it really true?? Ive heard this about peptides but Ive never noticed a subjective difference in product quality after mishandling them

    • @dlindo8892
      @dlindo8892 11 місяців тому +1

      No. Not as far as my experience. And it also lasts a lot longer than what’s been told. I’ve used mixed hcg that was 7 months old that had been stored in my fridge. I noticed no difference in the effects from a freshly mixed bottle.

    • @justinw1765
      @justinw1765 5 місяців тому

      @@dlindo8892 The only peptide I've taken in melanotan. A hack to keep it even longer is to buy some copper tape, adhere some aluminum foil to the sticky side. Put the smooth, copper side down around the rubber top, tighten it around it until it is as sealed as possible (putting a twist tie or rubberband to keep it tight can be a good idea). Both copper and aluminum foil block gaseous transfer, while copper is highly antimicrobial as well. Essentially this keeps both air/oxygen and microbes from getting in. Both will prolong its useful life. Store it in the fridge when not using. A combo of these two will keep your peptides fresher for longer.

    • @wa2k360
      @wa2k360 4 місяці тому

      Lol not true

  • @kimbrinks8918
    @kimbrinks8918 3 місяці тому

    Could you please footnote the studies you reference?

  • @richardarcher6838
    @richardarcher6838 5 місяців тому +1

    Am 67. At 65 I grew boobs in 3 weeks, had loads menopause symptoms. Doctor did fasting blood test: T was 24 out of 28 "normal" Doctors tell me nothing wrong with my hormones and am walking around with breasts! - obtained Clomid online (as in UK) took quarter tab every 2 days It took weeks n weeks but slowly everything started to work again. Great. then Clomid shut down my nuts. Now if I have even 2 doses Comid everything dries up. I'd have continued cycling Clomid as my muscle improved n my fists chunked up all meaty, but as I say, cant use Clomid cz destroys my seminal output. Anyone help me with this lot please?

  • @frankwoods4532
    @frankwoods4532 6 місяців тому +1

    Delayed Ejeculation, being seen by a Doctor but would like more information.😨☹ Thank you!

    • @anguslean4058
      @anguslean4058 4 місяці тому

      Get your prolactin levels checked.

  • @agi-news
    @agi-news 9 місяців тому +1

    I was wondering if it blocks estrogen, does that actually block the effects of estrogen or does it just make it so your brain thinks that there isn't enough estrogen. If it just tricks your brian into thinking there isn't enough estrogen but there is, that would make you produced a lot more estrogen than you need. which could cause gyno. In the other case. if it actually blocks and makes that originally created estrogen not used, then your brain would kick up production of testostorone, in order to make that usual normal range of estrogen, so it would increase the testostorone with out really changing the levels of estrogen. Would anyone be able to let me know which of the two cases it is with Enclomophene?

  • @themeximurican90
    @themeximurican90 7 місяців тому +14

    I took clomid/clomofeno from mexico for awhile. Testosterone went from 300 to 950. My libido was equal to that of a teenager 🤣

    • @elinino5275
      @elinino5275 6 місяців тому +1

      It's probably the one they are saying FDA didn't approve. Now you know why 😂

    • @zach3955
      @zach3955 5 місяців тому

      @@elinino5275 that’s enclomiphine not clomiphine (clomid). I’m on clomid in conjunction with anastrazole which has the same effect as enclomiphine.

    • @EzioAuditoreDeFirenze23
      @EzioAuditoreDeFirenze23 2 місяці тому

      what was your dosage

  • @ChrisPuckett
    @ChrisPuckett Рік тому +12

    What is the best way to treat high SHBG?

    • @gregorystacey2470
      @gregorystacey2470 Рік тому +2

      Me too. SHBG is generally 120 genetically (it seems). Total was 700 but free was 7. On trt 100mg/wk x6 weeks and up to 860 total and 8.6 free. Now up to 130mg week and donating blood (high h/h and iron), taking boron, and maximizing vit d. Hoping all this works. Doc wants my free t 20+!

    • @AmritGrewal31
      @AmritGrewal31 11 місяців тому +3

      Drop carbs and you'll crash your SHBG; ask a keto junkie

    • @rafaelgoesmann3399
      @rafaelgoesmann3399 11 місяців тому

      @@gregorystacey2470 What is your SHBG after starting the trt?

    • @gregorystacey2470
      @gregorystacey2470 11 місяців тому +1

      @@rafaelgoesmann3399 It was 119 after 6 weeks, virtually no change

    • @jimt7681
      @jimt7681 9 місяців тому +2

      ​@@AmritGrewal31No wrong. Sorry just wrong.

  • @thecastle09
    @thecastle09 Рік тому +1

    Getting it legally from places like you represent is very expensive not everybody can afford that so they’re willing to risk getting it from somebody. They know at the gym.

  • @goyacar
    @goyacar 11 місяців тому

    What is the recommended biweekly dose for testosterone cypionate?

    • @askingwhy123
      @askingwhy123 11 місяців тому +3

      There's a ton of well-documented, self-reported case studies from "shut down" bodybuilders and they all say: bi-weekly is bad. Aim for as many small doses as you can tolerate, eg weekly, every 4-5 days... The large depo shot every 2 weeks pingpongs T levels--too much at the start, not enough at the end.

    • @dlindo8892
      @dlindo8892 11 місяців тому +6

      50 mgs twice a week. Like Monday morning and Thursday evening

    • @antondeklerkdrtony3d412
      @antondeklerkdrtony3d412 11 місяців тому +3

      ​@dlindo8892 you know your stuff mate💪 patient will have lower e2 by splitting the doses and that's dose will get him well over 1000ngdl

  • @BR-dn7hw
    @BR-dn7hw 8 місяців тому

    U just write unique

  • @llame_az
    @llame_az 11 місяців тому +6

    i've been using HCG from an indian pharmacy at a cost of 20/usd per 10k IU vial with great success. there is no need to get ripped of by the US pharma system

    • @Rob-bq6ek
      @Rob-bq6ek 9 місяців тому +1

      Which pharmacy?

    • @banana_1992
      @banana_1992 8 місяців тому +4

      The concern with foreign compounding pharmacies is lack of regulatory standards/testing/inspections leading to uncertainty about purity and potency. It’s great you’re getting good results, just make sure you’re not injecting something with impurities / unknown chemical byproducts into your body. Out of curiosity, what’s the name of the pharmacy you like?

    • @llame_az
      @llame_az 8 місяців тому

      @banana_1992 reliablerx pharmacy most usa drugs come from china/india anyways

  • @by1591tanker
    @by1591tanker Місяць тому

    I’m 33 low test. Slightly low LH. Any suggestions? My doctor is going to start me on clomiphene. And I’m also getting a sleep apnea test because she said it could also be affecting test and LH.

    • @alexandruturza7131
      @alexandruturza7131 Місяць тому

      Start a low carb diet with lots of eggs, fish and fatty meat.
      As a testosterone booster you can tale 10 mg of tamoxifen per day.
      This will increase your levels for sure

  • @Officertack
    @Officertack 8 місяців тому +2

    I had to hop off the juice due to heart problems, was on juice for about a year and I've been off for about 4 months. My libido is completely dead, I was thinking of getting on clomid to see if it would change anything

    • @tihruytssgjjvsavcxtbvhj3429
      @tihruytssgjjvsavcxtbvhj3429 8 місяців тому

      Use the other form. Safer than clomid and more effective.

    • @Makalotfn
      @Makalotfn 5 місяців тому

      @@tihruytssgjjvsavcxtbvhj3429what’s the other forms name?

    • @tihruytssgjjvsavcxtbvhj3429
      @tihruytssgjjvsavcxtbvhj3429 5 місяців тому

      @@Makalotfn enclomiphene. Safer and more effective than clomid.

    • @MarylandGuy-ey3st
      @MarylandGuy-ey3st 2 місяці тому

      You didn’t boost yourself to super physiological levels did you?

    • @loopba
      @loopba 3 дні тому

      DM me if thinking of going on the juice and looking for something to look like Kim Jong Un. A gel you can rub on your balls

  • @brunosantospereira4459
    @brunosantospereira4459 6 місяців тому

    Does clomid cause bad eye sight? Does it make you blind?

  • @gummiesrule88
    @gummiesrule88 7 місяців тому +4

    Unfortunately, the discussion of "enclomid" (enclomiphene) is abbreviated here, with no discussion at all of its advantages over clomid.

    • @MrSamslab
      @MrSamslab 5 місяців тому

      I hear it's inexpensive, so not really prescribed by doctors. No profits smh

    • @Nemy360
      @Nemy360 2 місяці тому

      Enclomiphene amd enclomid are 2 different drugs

    • @VernCrisler
      @VernCrisler Місяць тому

      @@MrSamslab Doctors can only prescribe FDA approved drugs. If it's still investigational, then lab rats have to use it without a prescription.

  • @gavinschneider7420
    @gavinschneider7420 8 місяців тому +3

    Holy shit Peter let your guests speak.

  • @gregberry8203
    @gregberry8203 Рік тому +4

    You’ve said you think Androgel is poor HRT choice. Why? You didn’t mention creams and gels as a delivery mechanism?

    • @ccon8
      @ccon8 8 місяців тому +1

      Anything cream or gel is not that effective as injections

    • @gregberry8203
      @gregberry8203 8 місяців тому

      @@ccon8 so Androgel no good? Useless or just not as effective as injectables? How much different?

    • @ccon8
      @ccon8 8 місяців тому

      @@gregberry8203 if you look up and compare, the research tells you that injecting is more effective than gel. Gel might be more practical but certainly not as effective.

    • @konz2891
      @konz2891 7 місяців тому

      @@gregberry8203 It isn't useless but it isn't as effective as injection, also can't be used if you're in close contact with females, children and animals. It sticks around for a while on you and whatever you're wearing, bed sheets too. Seen plenty of people say it changed their life and seen plenty say it was a waste of time, ultimately depends on your own situation, worth a shot imo as not having to stab yourself a couple times a week is always good.

    • @N-xi2zh
      @N-xi2zh 6 місяців тому

      SOME prefere the creams compounded ideally. 20 percent strength or made at home on your own. Some prefer injections. More 5ar action and dht conversion with creams, esp on the scrotum. DHT and test cream on balls = godly I am sure, with the right diet, exercise, vitamins, etc.

  • @EvanFotis
    @EvanFotis 11 місяців тому +1

    Are there any instances documented where clomid affects eyesight negatively?

    • @infodave5813
      @infodave5813 8 місяців тому

      see above @urwhatueat2170
      @urwhatueat2170

    • @GertuCapur
      @GertuCapur 8 місяців тому +5

      Two months on Enclomiphene. I noticed a lot more eye floaters. But they don’t bother me too much.

  • @user-qh6wz1gb5n
    @user-qh6wz1gb5n 5 місяців тому

    I did test e for like 7 years how long do i need to use hcg an clomid hehe

    • @viktorfurer2671
      @viktorfurer2671 5 місяців тому

      Bruh I think you are done, you will do trt for the rest of your life

    • @StelioKontoss
      @StelioKontoss 23 дні тому

      You have to stop, Attia said 2 years max 😬😂🤪🤪

  • @revilooliver486
    @revilooliver486 29 днів тому

    hcg shuts you down??

  • @brianpulley8652
    @brianpulley8652 9 місяців тому +4

    All I know is I had my testosterone checked and it was 9.2 out of a range of 7.2 to 24 and I've felt like total 💩 the past 4 years and I'm now 51 and my doctor said oh you're fine you're within normal range and if I weren't religious I'd have already ended things because it's horrible living with zero motivation and energy and nothing OTC seems to do anything.

    • @Alwaystrollingbro
      @Alwaystrollingbro 8 місяців тому +3

      Are you overweight? Is your diet poor? Are you sedentary? If you answered yes to more than 1 of these then you have your answer to why your T is low and you don’t need anything otc, you need discipline and hard work. You are getting up in age but that test level is low for a 51 year old.

    • @banana_1992
      @banana_1992 8 місяців тому +4

      I cannot tell you how common your story is. >90% of doctors have no clue what they’re talking about when they say “you’re in normal range, don’t worry about it” and wave you away. The Free T level that you’re reporting here, combined with your symptoms, is a VERY strong indication for treatment and the consequences of not treating it far outweigh the risks of TRT.
      (This is coming from someone who works in this field and hears stories like yours from my patients everyday. It’s extremely frustrating for us who specialize, knowing so many men are denied help from ignorant/inexperienced practitioners who wave them away)

    • @brianpulley8652
      @brianpulley8652 8 місяців тому +3

      @@banana_1992 it's so frustrating and to top it off I'm a single dad of 2 wonder kids and they definitely deserve the best version of me and it's a struggle every day to just make it through the day....I'm switching doctors in hopes of finding one who understands.

    • @banana_1992
      @banana_1992 8 місяців тому

      @@brianpulley8652 Depending on your location, a reputable private clinic is typically your best resource compared to general primary care, urology, and endocrinology clinics. You really need someone who specializes in testosterone specifically, because there is so much misinformation and inexperience among the medical field in general when it comes to these issues, even among endocrinologists.
      Just be careful when selecting the clinic, as there are many shoddy clinics / snake oil salesmen in this industry. Look for somewhere that’s been established for several years with stable experienced staff and reputable reviews. You’re going to feel much better after a few months of being on a proper regimen, it just needs to be monitored and managed properly by someone trustworthy. Best of luck.

    • @wigletron2846
      @wigletron2846 8 місяців тому +3

      I was in your situation except total test was 130 at only 36. I compete in natural bodybuilding so I'm not fat and diet is good. Dr wouldn't help because of my age and im in shape. Go to a clinic. Yes they just want to set you up on monthly payments but it's worth it to get your life back. I've wasted more money on supplements that don't work. If it makes you enjoy life and not want to end it everyday then it's worth every penny.

  • @Robert-cd5zr
    @Robert-cd5zr 5 місяців тому +3

    Is there an option that doesn't require you to be on it for life by permanently shutting down normal testosterone production?

    • @jcgales2254
      @jcgales2254 3 місяці тому

      Enclomiphene citrate doesn’t shut down natural production. If you stop taking it your levels will just drop back down to where they were before you began taking it.

    • @raju123ban
      @raju123ban 15 днів тому

      Enclomiphene

  • @michaelbattista1334
    @michaelbattista1334 2 місяці тому

    Used to inject T until I realized it was destroying my voice. For someone who sings for a living this is a major problem.

  • @shaheryarnaqvi8
    @shaheryarnaqvi8 6 місяців тому

    Enclomophine citrate seems the best bet

  • @BruceLee-lx6zh
    @BruceLee-lx6zh 4 місяці тому

    Enclo is far better option as a trt than any of the current treatment you told

    • @user-hg1dl6lk3u
      @user-hg1dl6lk3u 3 місяці тому

      I asked for Enclomid. endocrinologist said that it’s not sold in the US.

    • @zackgro8440
      @zackgro8440 Місяць тому

      @@user-hg1dl6lk3u it's compounded

  • @mikevasquez1103
    @mikevasquez1103 7 місяців тому +1

    My libido is trash. My confidence is trash. I am hypertensive even after sorting out my diet and losing weigjt as in I take an ACE inhibitor, a beta blocker, a calcium channel blocker, and a vasodilator. I am rapidly losing hope.

    • @sasquatch8268
      @sasquatch8268 7 місяців тому +1

      Are your kidneys in check? There’s gotta be other things at play here if you lost weight and decreased sodium in your diet.

    • @mikevasquez1103
      @mikevasquez1103 7 місяців тому +2

      @@sasquatch8268 I have a transplant. It's good though.

    • @TheBanderson22
      @TheBanderson22 7 днів тому

      You need to be worked up for secondary causes of hypertension. You could have an ACTH secreting adneoma or various other causes. You define criteria to look for other causes.

  • @b-bigb1426
    @b-bigb1426 5 місяців тому

    On enclomaphene for 2 months now.... Great lab numbers..... Sex issues YES!! Feel Blahhhh! I'm getting off.

  • @user-ff1xu8ru6t
    @user-ff1xu8ru6t 16 днів тому

    Thank you Dr Igho for the professionalism with which you do your work. You listen to your client and always put their needs first to ensure they live another day healthy and vibrant. I never thought there was a way to Enhance my penis size and girth naturally using herbal remedies, your medicine has not only shown me but has also shown the world how effective herbal medicines really are.

  • @mirapilates
    @mirapilates 7 місяців тому

    Been on Clomid for 3 months. Did not get a big increase. 380>460. I was expecting higher and did not get improvement in libido. Estrodial is in normal range. I wonder what the underlying issue is.

    • @eray9934
      @eray9934 6 місяців тому

      It would be interesting to see what your LH increase was before/after Clomid.

    • @nickolas9375
      @nickolas9375 6 місяців тому

      Same here. Dkd yoh test you LH levels pre and post Clomid? ​@@eray9934

  • @chappod1990
    @chappod1990 11 місяців тому +2

    What is the dangers of trt long term ?

    • @jovialjayou
      @jovialjayou 11 місяців тому

      Infertility. High blood pressure, escalated risk of heart related issues.

    • @GreenTorque
      @GreenTorque 11 місяців тому

      @@jovialjayou quality over quantity

    • @jovialjayou
      @jovialjayou 11 місяців тому +2

      @@GreenTorque I don’t know what that means

    • @johnnykilo4967
      @johnnykilo4967 11 місяців тому

      @@jovialjayouYou’re giving bad genetic info that was the standard decades ago. Educate yourself before you type.

    • @jovialjayou
      @jovialjayou 11 місяців тому +4

      @@johnnykilo4967 I’m well educated on the matter. Before you start ANY TRT protocol, your doctor would advise you of these risks. There’s a reason body builders and other steroid users can’t have kids and die prematurely.

  • @Surge308
    @Surge308 6 місяців тому

    I don’t think it was Mercks patent. It got classified as a biologic and got wrapped up in a stupid regulation. BRING HCG BACK FDA 🖕🖕

  • @finbarh6
    @finbarh6 4 місяці тому

    My test is 6.9n/mol & sperm count 1 million per mil, which is because a dead person 🤦🏽‍♂️ would you suggest hcg & clomid 1500/2000 iu 3 times a week plus 50mg clomid eod

    • @finbarh6
      @finbarh6 4 місяці тому

      I’m also I’m the process of seeking Dr advice just wanted to see what others think from any experience

  • @Cas_anova
    @Cas_anova 4 місяці тому

    Just pin test.

  • @Proviron_God
    @Proviron_God 11 місяців тому +8

    I’m 45 I use enclomiphene 25mg MWF and got off trt and got my test from 0-1000 in 60 days and I feel great. The first 45 days sucked though.

  • @iamthefiremanjj
    @iamthefiremanjj 7 місяців тому

    Enclomid is a way better option

  • @Blackpants17
    @Blackpants17 10 місяців тому

    Can Enclomiphene ruin your libido?

    • @jimt7681
      @jimt7681 9 місяців тому

      No it only blocks the receptor for estrogen in the hypothalamus

    • @River20122
      @River20122 8 місяців тому

      That is technically not confirmed. What is confirmed is there are other estrogenic tissues that can been affected. For example, certain eye tissues.

  • @alexa3389
    @alexa3389 29 днів тому

    Wtf ??? Why they end it there????

  • @mikelindner2646
    @mikelindner2646 7 місяців тому

    Testosterone is way you replace testosterone, that’s it. Stay away from these other medications. HCG can be used along with testosterone if you want but HCG monotherapy doesn’t work.

  • @MegaUtube99
    @MegaUtube99 Рік тому +7

    I’m 24 years old. 179 testosterone. Doctor isn’t against giving me testosterone but would prefer me on clomid for 10-15 years until I have children.
    I would much prefer testosterone, but don’t know what to do

    • @30mattdavies
      @30mattdavies Рік тому +4

      Just add HCG to the test

    • @mmaslav6176
      @mmaslav6176 Рік тому +5

      Maybe first try to find out what is wrong with your body?

    • @MegaUtube99
      @MegaUtube99 Рік тому +1

      @@30mattdavies well yea I’d freeze my sperm beforehand and take HCG along with the test. I’m always hearing conflicting things though that’s why I’m unsure what to do. Everything I’ve heard about clomid makes me not wanna take it though

    • @MegaUtube99
      @MegaUtube99 Рік тому +3

      @@mmaslav6176 I mean the only thing that’s wrong is I have really low testosterone which is an epidemic today especially among younger men like myself due to micro plastics, poor diet and stuff like that. I went three months trying to raise it naturally through better sleep, working out, eating better and it somehow went down even more. There isn’t much you can do besides medical treatment to my knowledge

    • @mmaslav6176
      @mmaslav6176 Рік тому +1

      @@MegaUtube99 shit man. I am 10 years older and I have about triple your testosterone. where do you live? Did you increase muscle mass while working out?

  • @KennyLauderdale
    @KennyLauderdale 8 місяців тому

    Ahhhh so natesto is the cheat code

  • @ChamomileTV
    @ChamomileTV 10 місяців тому +3

    Treat your varicoceles!

    • @Rocko1990
      @Rocko1990 9 місяців тому

      Say what?

    • @_RezaTaheri
      @_RezaTaheri 5 місяців тому

      Can you please share why you say this? I'm about to get TRT

  • @EtienneLeBoeuf
    @EtienneLeBoeuf Місяць тому +1

    I went from 334 to 960 in around 3 months all natural no TRT. I found the truth about T. This book should be essential reading for all men. Written by a 50s guy with natural T levels of a 20s guy
    Complete guide to testosterone by james Francis

  • @wa2k360
    @wa2k360 4 місяці тому

    50 climid daily is insane wtf

  • @cski9148
    @cski9148 Рік тому +3

    What about women!😊

    • @metemad
      @metemad 11 місяців тому

      He has another podcast for women on this subject.

    • @eray9934
      @eray9934 6 місяців тому

      I love'em!

  • @IDGAF_PLUS
    @IDGAF_PLUS Місяць тому

    Clomid is expensive!!!

    • @jsol9lbc430
      @jsol9lbc430 27 днів тому

      Ask your doctor to change the fertility codes if possible for the pharmacy to reduce the cost. Worked for me and went from $400 to $15 with insurance

  • @ErikMagnethiDalgaard
    @ErikMagnethiDalgaard 8 місяців тому +1

    Simple: eat egg daily, nature's number one super food in a very practical package.

  • @antondeklerkdrtony3d412
    @antondeklerkdrtony3d412 11 місяців тому

    Enclophine, why are we even looking at other avenues? Enclophine healthy lifestyle and t will be where they should be... safe to say people go on the internet and talk about things they have no clue off this interview is the worst 😂😂 again hcg mimicks lh with that siad siad the brian will stop gnrh

  • @StelioKontoss
    @StelioKontoss 23 дні тому

    Wouldnt be on it more than 2 years..? Wtf😂 so 2 years of TRT and then done.. back to hypogonadism and then.. just die? 🤪

  • @infiniteworfare5089
    @infiniteworfare5089 Рік тому +1

    i think the best way to treat low testosterone is prolonged dry fasting and bed resting. this will lead to less inflammation overtime. i mean peter attia, alot of animals build alot of fat before winter and go long periods without food. they also spend alot of time bed resting. alot of people "think" they are primal but they are nowhere near primal and they dont act based on ancestors.

    • @infiniteworfare5089
      @infiniteworfare5089 Рік тому

      @Tom-qv2jg no. alot of people are already drinking too much water. thats why they get up at night to pee. its best to sleep a full night without getting up. each movement/time being awake = more inflammation. and muscle mass is irrelevant nowadays since robotics/AI is taking over. also muscle comes back very easily. just ask connor murphy.
      i did a 4 dry fast at only 113 pounds at 5'8" male, and i didnt die from it. i felt like i could have gone another 8 days still before something bad starts happening.

    • @recyfer
      @recyfer 11 місяців тому +1

      That may be the dumbest shit I've ever read. God have mercy on your soul

    • @jimg6970
      @jimg6970 11 місяців тому +1

      This has to be a joke.

    • @infiniteworfare5089
      @infiniteworfare5089 11 місяців тому

      @@jimg6970 your name is a joke

    • @modernlunacy4341
      @modernlunacy4341 9 місяців тому +1

      Maybe fasting does help. I only eat 2 big meals a day. One being breakfast, and the other being dinner. The rest of the time, I practice intermittent fasting, and I've felt a big improvement from when I ate 3 times + snacks. Idk about "dry fasting" though. I try to get in half a gallon of water a day, minimum.

  • @morganweller1491
    @morganweller1491 8 місяців тому

    Bruh explain all you're crazy scientifique stuff you talk about its l8ke listening to someone from another world

  • @helenbarrett6451
    @helenbarrett6451 5 місяців тому

    Clomid. So cant eat a bunch of soy and ur ok?

  • @NelsonMontana1234
    @NelsonMontana1234 9 місяців тому +2

    Clomid is a horrible drug.

    • @michaelr1011
      @michaelr1011 8 місяців тому

      Really? Why do you say that? I’m about to start

    • @AntonioGoldmanOficial
      @AntonioGoldmanOficial 8 місяців тому

      Clomid and Clomiphene are two completely different things, make your research before adding a comment my man, you are old enough to do the homework.

    • @NelsonMontana1234
      @NelsonMontana1234 8 місяців тому +1

      @@AntonioGoldmanOficial I was only commenting on Clomid. You''re trying to act more informed when you're really just being a dick.

    • @kennethknott9138
      @kennethknott9138 8 місяців тому

      @@michaelr1011 Study enclomiphene. All of the benefits of Clomid and none of the drawbacks.

    • @eray9934
      @eray9934 6 місяців тому +1

      @@AntonioGoldmanOficial No, Clomiphene is the generic name of the drug, Clomid is a brand name...

  • @jimt7681
    @jimt7681 9 місяців тому

    We never used HCG. That is false. It doesn't work.

  • @kunta-kinte0904
    @kunta-kinte0904 10 місяців тому +3

    Same medications for testosterone for last 60 years and we wonder why we have lower testosterone then womens in 60s😂😂