Gut Microbiome and Healing Leaky Gut

spencerinstitute.com/certific... Learning about gut biomes and leaky gut syndrome is one aspect of the Spencer Institute Integrative Health Coach Certification. In obesity and diabetes, abnormal gut microbiota and increased gut permeability (leaky gut) are common risk factors which in turn contributes in increasing chronic low grade inflammation.
Leaky gut, also known as intestinal permeability, is a pathological condition that allows food and gut microbiome components to uncontrollably leak from the intestines into our bloodstream. In severe cases, entire microorganisms can cross directly into the bloodstream, causing a variety of chronic and infectious diseases. A healthy intestinal lining, on the other hand, only allows beneficial nutrients to enter our bloodstream.
The intestines are protected by a single layer of specialized epithelial cells that are linked together by tight junction (or TJ) proteins. As one 2020 review explains, leaky gut symptoms are a consequence of intestinal TJ malfunction.
Gut-Immune Axis
As we are discovering, these gut microbes have different communication channels they can pull on to talk to the different tissues. Since the gut microbiome also has a powerful effect on the immune system via the gut-immune axis, might this whopping 2 kg of microbes living in our intestines help modulate infection risk in some of these other tissues?
Are you interested in earning your professional credential on this topic? Would you like to have a thriving career helping others? Click the link above for details.