Why B12 Is Crucial For Mood Regulation | An Easy Guide To Vitamin B12 | Zooki

Low vitamin B12 levels are strongly correlated with the prevalence of depression, anxiety, and other mood disorders, which can be explained by Vitamin B12’s direct impact on the synthesis of serotonin, dopamine, and norepinephrine: neurotransmitters that are vital for regulating mood, motivation, and the stress response.
Additionally, vitamin B12 is involved in the metabolism of homocysteine, an amino acid linked to an increased risk of cardiovascular disease and cognitive decline. High homocysteine levels may contribute to depression by inducing oxidative stress, inflammation, and neuronal damage in the brain. Vitamin B12 may also influence the regulation of brain-derived neurotrophic factor (BDNF), a protein essential for learning, memory, and mood regulation.
Those experiencing mood disturbances, particularly those at risk for deficiency such as vegans, vegetarians and the elderly, may benefit from discussing vitamin B12 supplementation with their healthcare provider as part of a comprehensive approach to mental health management.
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