Breast Cancer Breakthrough - Targeting Sleeping Breast Cancer Cells || Dr Liz O'Riordan

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  • Опубліковано 20 січ 2025

КОМЕНТАРІ • 132

  • @deborahbizzell1989
    @deborahbizzell1989 10 місяців тому +35

    Great news.This happened to me a couple of times.I thought it wasn't coming back,but after 12 yrs.it did,and after 11 yrs.it returned again.I hope to God that this will help us all affected by breast cancer.😊

  • @goldentarot3914
    @goldentarot3914 9 місяців тому +68

    I’m stage 4 Metastic breast cancer to my bones got diagnosed 18 months ago and I’m hoping that any new treatments will come along to help me and others who have to live with this. Thanks for the updates. Stay positive everyone

    • @lanebashford3982
      @lanebashford3982 9 місяців тому +18

      You and I share the same diagnosis. My cancer spread to my spine, ribs, arm and lung. I'm 3 years since diagnosis and doing well on Verzenio and Letrozole. Other than fatigue, I'm doing well and pretty much without pain or other problems. Eating and sleeping well. Hope you are doing fine, too.

    • @suegray6284
      @suegray6284 9 місяців тому +14

      I had no idea my aggressive breast cancer would return after 12 years, I’m gutted to know I went through so much treatment but never truly got rid of it…I’ve now had 3 operations, 8 months of chemo, 31 days of radiation and I’m on ribocyclib and letrozole. Every day is a bonus. Apart from being a bit more tired I am able to do most things I did before treatment including an 18 mile walk to raise money for cancer research last year. I hope the new research can produce therapies that will help us 🙏🏻🙏🏻🙏🏻

    • @radhanaidu9979
      @radhanaidu9979 9 місяців тому

      ​@@lanebashford3982 hi I am struggling with stage 4 breast cancer and spine mets with pain, how are you coping?

    • @ninanicefrench1013
      @ninanicefrench1013 9 місяців тому +6

      Seems like I’m reading my story same dx. I’m on RIbo and letrozole my joints hurt so bad. Had a double mastectomy

    • @marlismueller4496
      @marlismueller4496 9 місяців тому +8

      How do you deal with the fear of dying soon? I am asking because I feel very traumatized.

  • @jpb1085
    @jpb1085 9 місяців тому +20

    Thank you! Late recurrence is something that deserves more attention now that, thankfully, so many of us are surviving our initial cancer.

  • @theresahickscch6581
    @theresahickscch6581 10 місяців тому +32

    That’s me - 23 years with radiation and tamoxifen on board. I thought I was done; obviously wrong. New theories and research bring good news for us. Thank you Dr. Liz for sharing the latest research.

    • @gena.9564
      @gena.9564 9 місяців тому +4

      What was your tumor type? 😢

    • @theresahickscch6581
      @theresahickscch6581 9 місяців тому

      @@gena.9564 HR positive, HER2 negative, no lymph nodes involved

  • @RovingReader
    @RovingReader 10 місяців тому +19

    This is 100% my mom- 17 years! Thanks so so much!

  • @elainespeirs7800
    @elainespeirs7800 9 місяців тому +9

    Since im not even at year 1 cancer free this us very encouraging news. I hope new treatments come soon

  • @nyla3235
    @nyla3235 6 місяців тому +5

    Thank you for your videos. I've not yet arrived at a year since my mastectomy ( will be a year Oct 20, 2024) and I'm always drinking up all the information I can learn. It is definitely a journey and everyday is an opportunity to grow in my knowledge and ability to understand how to best take care of myself. I hope this will one day be conquered and if not by a cure hopefully total prevention. I wish you the best and thank you for educating.

  • @kdclothes
    @kdclothes 10 місяців тому +7

    Thank you for this video. this is my case. I just healed from my surgery.

  • @gemmac3371
    @gemmac3371 10 місяців тому +14

    Thank you for the video, I was stressing about this so much as this is the type of cancer I had. So glad you are around for this amazing information. ❤

  • @Adishaktiparashakti369
    @Adishaktiparashakti369 9 місяців тому +28

    I had read about this research too, but they say it will take 5 to 6 years for these medicines, if they can start covid vaccine for energency use, i wonder why these medicines should take so long.

    • @beautifulvictory9683
      @beautifulvictory9683 9 місяців тому

      Keep in mind, the C0vid v@xine was released on an experimental basis as well as emergency. The side effects are coming home to roost & are being discovered well after. There is no recourse for those that experience the said side effects. That's why it takes so long, to work out the potential issues.

    • @HL-qv3yd
      @HL-qv3yd 9 місяців тому +6

      That exactly my question too

    • @mochipii
      @mochipii 2 місяці тому +3

      Because there is more money coming in with regular treatments than cure.

  • @BeateSchierle
    @BeateSchierle 10 місяців тому +7

    Thank you so much, Liz! You are keeping informed us so extremely well...An amazing finding for future therapies. Not for all of us perhaps - my recurrence came after eight years - , but for many women to come.

  • @Debilee16
    @Debilee16 10 місяців тому +14

    This is reassuring, I had her2 positive breast cancer ,was caught early stages 2 ,had mastectomy, but was told I didn't need Radiotherapy not sure why ?I'm on kadcyla now got 4 more to go and given Exemestane inhibitors but finding the side effects quite bad ,real bad bone pain in hands ,arms very tired ,I have to keep taking a break from them ,I no alot of women stop taking these ,but I'm scared the cancer might come back so hearing this if it comes off gives us hope 🙏

    • @susanelizabeth5841
      @susanelizabeth5841 10 місяців тому +2

      Your experience is similar to mine - also no radiation. Could you please share your stage and Oncotype DX score?
      Thank you.

    • @endlessdelirium213
      @endlessdelirium213 10 місяців тому +3

      I had to come off Exemestane due to the pain in my joints and legs. I've managed better since the hospital put me on Tamoxifen

    • @MC37138
      @MC37138 9 місяців тому

      If the cancer does not reach lymph nodes….then radiation is not needed…that is what I was told….

    • @angieposton8377
      @angieposton8377 9 місяців тому

      I’m on Tamoxifen and have a few night sweats but doing great on it.@@endlessdelirium213

    • @lisatorigian837
      @lisatorigian837 9 місяців тому +1

      Who gets the Exemetanse ?

  • @HL-qv3yd
    @HL-qv3yd 9 місяців тому +6

    Thank you dr Liz, following up and informing us, very great full.

  • @monikaengel5515
    @monikaengel5515 9 місяців тому +17

    Im almost 5 years survivor estrogen positive bc continues anastrozole with zokadex injection i hope never ever will had recurrence but its soo hard 😢live in fears if anastrazole keep cancer away i will continues as long as i needed but side effects not great stiff joints mornings ,fatigue,dry skin sleep issue but continues fasting eating clean and daily 4 miles and weights 💪

    • @FuneraryGirl
      @FuneraryGirl 4 місяці тому +2

      Sounds like we are the same, but I am on oral palbociclib with anastrozole. Here’s to us flying past the five year mark and enjoying many more years 💜💜

    • @bbaestheticsbynyma
      @bbaestheticsbynyma 4 місяці тому +1

      Sending prayers 🙏 ❤

  • @mozinvite4175
    @mozinvite4175 Місяць тому

    I'm an oncologist and your videos are very informative. Thanks

  • @robbar42
    @robbar42 9 місяців тому +3

    thank you very much for sharing. This is a positive boost of emotional energy

  • @HL-qv3yd
    @HL-qv3yd 9 місяців тому +10

    I hope they discover cure for this cancers very sooner.

  • @KTen-cm6wx
    @KTen-cm6wx 10 місяців тому +6

    Dr. O’Riordan, I love you for the information and education that you share with us. Where can I find in the US the groovy kool frames you wear. Happy Easter ❤

  • @Katsem
    @Katsem 10 місяців тому +9

    I’ve had hormone sensitive breast cancer twice, the second time after 7.5 years. I was told by my oncologist that my aromatase inhibitor did NOT kill cancer cells, but changed the environment so the chance of cancer cells growing was reduced. But I think what’s been said here is that aromatase inhibitors actually kill the cells, aside from these sleeper cells. I’m pretty confused.

    • @missw2
      @missw2 9 місяців тому

      Your oncologist is correct. AI's work by blocking the conversion of androgen to oestogen in the body thereby removing a source of 'fuel' for an oestrogen-driven cancer to grow.

    • @youownawebsite
      @youownawebsite 9 місяців тому +4

      Yes Ive asked Liz to please clarify and correct her info about hormone blockers' killing ' as its confusing

    • @beautifulvictory9683
      @beautifulvictory9683 9 місяців тому +3

      I was under the impression that the environment changed as well. Not kill so to speak. My Onco did say an aromatase inhibitor is more effective than Tamoxifem. 🤔

  • @RCB2010
    @RCB2010 9 місяців тому +6

    Do we know the percentage of Er+ primaries that go on to metastasise? This is fantastic news for women in the future. Thank you to the wonderful research scientists!

    • @bosslady5163
      @bosslady5163 9 місяців тому +3

      I read somewhere that about 30% 😢

  • @LiseCorbat
    @LiseCorbat 8 місяців тому +3

    What happen in case we never stop taking anti aromatase therapies?

  • @melindavalle173
    @melindavalle173 10 місяців тому +3

    Thank you, thank you, thank you! ❤❤❤

  • @erika_koos
    @erika_koos 9 місяців тому +3

    Hello Dr. Liz! Thank you so much for sharing these exciting news. I know it might be early to ask but do you see it possible that patients who are already under anti-hormone treatment can also benefit from this discovery? Dr. Magnani mentioned that patients would receive this treatment from the early days of starting the aromatase inhibitors.

  • @DCGreenZone
    @DCGreenZone 9 місяців тому +7

    The City of Hope is adding Ivermectin to TNBC treatment, University at Glasgow is adding Mebendazole to Docetaxel for PC, Dr. Marc-Eric Halatsch is using Itraconazole in a 9 repurposed drug protocol for Glioma and Glioblastoma. Dr Tom Rogers YT video on Artemisisin and Fenbendazole has some comments you may be interested in.

    • @laradiantrr9357
      @laradiantrr9357 8 місяців тому +1

      That's great to hear that City of Hope is adding Iver. into their treatment possibilities! Do you work there or know anyone there so you are knowing this info. as fact?

    • @DCGreenZone
      @DCGreenZone 8 місяців тому

      @@laradiantrr9357 Sorry, I don't know anyone there, I don't work there... but I do Google for the latest information on the Azoles and Avermectins. Check out University at Glasgow, PC and Mebendazole for another treat. The City of Hope web announcement is there if you search for it.

    • @DCGreenZone
      @DCGreenZone 8 місяців тому

      @@laradiantrr9357 I answered you and my response was evaporated. Use Google to find University of Glasgow and Mebendazole, City of Hope and Ivermectin. Let's see if I broke any rules this time.

    • @DCGreenZone
      @DCGreenZone 8 місяців тому

      @@laradiantrr9357 Unable to respond. Ministry of truth is at it again.

  • @mfinn7880
    @mfinn7880 9 місяців тому +2

    Thanks, Dr. Liz, I so trust your brilliant wee videos, 😀 thanks so much 🙏 😀

  • @earthwalker8277
    @earthwalker8277 9 місяців тому +4

    Does this potentially apply to both ER+ HER2- and triple positive breast cancers?

  • @iconic1758
    @iconic1758 3 місяці тому +3

    Is there any breast cancer patient who has used lugols iodine for breast cancer

  • @Sarappreciates
    @Sarappreciates 9 місяців тому +2

    Dr Liz, thank you! My mother died of pneumonia in February weeks before the worst PET scan of my cancer case so far. I'll begin a new therapy to treat MBC with mets in lungs and bones: TRUQAP instead of Ibrance now. Everything in my treatment is changing except for Lupron. My bone mets will now be treated with the infusions of Zometa to prevent spinal fractures. Rather than oral Arimidex or Letrozole, I'll be getting Faslodex injections, one in each hip every month, then another injection of Lupron. It feels like so much to take in all at once. I don't know how to keep my brain from exploding! 🤯 One day at a time, I guess.

  • @jahlin4250
    @jahlin4250 8 місяців тому +2

    Do breast cancer cells enter this sleep mode if one is treated with Tamoxifen?

  • @TrudyContos-gq1bw
    @TrudyContos-gq1bw 3 місяці тому +1

    but really is shocking that most of these oncologists researches never compare who has thyroid pituitary gland issues people with thyroid disease go through a pre-post during menopause before they even hit perimenopause I was one of those what Hashimoto's still?
    I didn't have anybody actually rephrase it I didn't have anyone of my doctors specialist oncologist radiologist discuss all the issues in all my pet scans even MRIS and I'm talking about the incidental that they found whichscared me much more than a cancer
    so like comorbidities led me to have it completely lost ofmy right Vision in right eye and so many surgeries gas bubbles oil silicone oil any left eye that's poor vision but I was able to save it now
    I want to know every pet scan after my lumpectomy and after my treatments confuse me as to it says no cancer is seen however they Mark the Spot residual to the left breast not excluded this came up quite often
    my question is to you how does a radiologist oncologist hematologist or a surgeon so in other words the multi-disciplin team decipher because I don't see any post notes dating oh well we all looked at this these skins and feel it to be out of concern and it's just benign tissue the last one said soft tissue very unusual because the same area on another skin said a post over there if I process from radiation treatment
    and because I had prior 7 years ago Pullman plural thickening which is scarring I don't care how many times I leave them all my reports and everything nobody seems to be concurring at all with prior images prior reports it'll Spade of details up my original diagnosis that was such
    and Injustice and has everything to do with dense breasts
    you know how does one that see residual not excluded how do you decipher this as a team because there are different teams that are involved and there's only one team that's screwed up my diagnosis from another Centerleaving me no choice but to havean unnecessary second biopsy 5 month delay so what was early early IDC with dcis spread to lymph nodes knowing that it was in IDC with a subtype up tubular cancer not sure it was mixed and two-faced tiny tumor with dcis and the IDC arising within radial scarring and the gcis papillary cred form and after post-operative the very next day of the pathology the lymph node negative to positivefor the surgeons operative notes
    pathologist also noted that it was impossible to get any clear margins because of the two were being two-sided and the two biopsies just took this tiny teeny based up the car so no more with the dcis and just he finally got it apart and I guess the following day with that again thank God and saw that it was a positive lymph node doesn't indicate actually if they took three lymph nodes I sent it alone or but he indicated that the regional node positive and and put it as metastatic carcinoma
    so you could see my concern with
    with residual not excluded I asked for a double mastectomy as soon as I walked in I said listen I have no emotional attachment to take them both she said this is not how we go about it I bring this to my that was after having a positive IDC three pathologist originally concurred that it was definitely IDC present however they highly recommended a full excision to detect any further breast tissue affected or whatever however they couldn't get a good prognostic on the marker so three pathologist concurred go see a surgeon her team said it was benign and then it's a long story after that anyway so you could see my concern of a residual not excluded
    however..
    I went around to the pathologist and he said they don't know how to treat this or what course of treatment because it's a very rare situation tubular cancers IDC tubular type that I said it's not a pure type and he said no he said it's like a roll of a dice and it's up to you
    you said you could go aggressive when it comes back you know I think you truly was telling me wait until it comes back to go full blown because it's already probably too late to get a mass activity right because I already had to run back to me they didn't do things uniformly at least
    yes it was Dory Cobra diagnosed in 2019 of December surgery May 12th 2020 delays not do to the patient myself but because things were missed things with misdiagnosis
    and he would not do anything until I had that second biopsy which I believe hit the IDC and the gcis was maybe hanging on by it's crib web-like form sit right through one of those holes and a hooked on to that IDC that was so teeny teeny tiny at the time

  • @hananezzat7973
    @hananezzat7973 9 місяців тому +2

    My mother has here disease recurrence both breas each five years apart and recurring in her right side twice why dose that happend very close

  • @claudiacicesa
    @claudiacicesa 10 місяців тому +4

    Thank you for sharing this great news with us. Hope studies clinical fase I-IV go right and soon we have more options to treat/avoid properly hormonal breast câncer recurence.

  • @svaught1
    @svaught1 Місяць тому

    Is he talking about targeted therapy like Verzenio? I could not tolerate that. I am on Exemestane because I couldn't tolerate Letrozole. It is an Aromase Inhibitor. I hope this is different. It's exciting I'm hopeful. I have a high risk of recurrence.

  • @Karkic
    @Karkic 8 місяців тому +1

    Dr. Riordan I love your content! I would love to know your thoughts on Duavee for breast cancer survivors looking for menopause relief.

  • @youownawebsite
    @youownawebsite 9 місяців тому +5

    yes please clarify and correct your info about hormone blockers' killing ' when they dont as its confusing

  • @helenjunell6271
    @helenjunell6271 День тому

    What about the people that have taken fendbendazole or ivermectin and the cancer is gone?? Totally gone!! What is more research not being done on that? My cousin is a prime example of it!! 7 years cancer free and he only did 1 chemo treatment. It made him so sick he refused it. They told him they did NOT get all the cancer when they did the surgery. Colorectal cancer. I want to see studies on this!

  • @vanessacampbell4655
    @vanessacampbell4655 9 місяців тому +4

    Does this apply to metastasized breast cancer also? I know it's just the beginning stages of the research but if the cancer is already stage 4 and in other parts of the body, will this help those people also?

    • @HL-qv3yd
      @HL-qv3yd 9 місяців тому

      I like to know answer this question too

    • @dazed_and_amazed1296
      @dazed_and_amazed1296 4 місяці тому +1

      I think this is a game changer and a potential for benefit for MBC

  • @cynthiayee5116
    @cynthiayee5116 10 місяців тому +7

    I have just saterted 6 month tamoxifen ...For 5 years

    • @mfinn7880
      @mfinn7880 9 місяців тому +2

      Thanks for sharing that 👍 bless you

  • @bcourtney4024
    @bcourtney4024 10 місяців тому +1

    So fabulous.❤

  • @naheedakhtar4815
    @naheedakhtar4815 9 місяців тому +1

    Hi i was diagnosed with breast cancer stange 2grade 3 her 2 positive i only had 2 chemo cycles whale doong my resuch i stop my chemotherapy due to sideaffects i had sugery but all so refferd radiotherapy its been 6 weeks i am on tamoxifen i am thinking to give up due to sideaffects in future i stll haven't recovered from chemo yet it has been 6 months only by having 2 chemo cycles just imagine if i had all 6 .
    Can you advice me what about if i took tamoxifen twice a week to avoid sideaffects do you think am i doing the right thing or take medicine 1 day and miss 1 day .
    Or if i completely stop tamoxifen what can i do instead

  • @brianmurray9405
    @brianmurray9405 9 місяців тому +3

    Amazing !! So does it work on mets disease anyway it’s good news

    • @dazed_and_amazed1296
      @dazed_and_amazed1296 4 місяці тому +1

      I would think the science would help MBC. If they can find a way to target proteins that can potentially help MBC.

  • @MarjanVahdat
    @MarjanVahdat 4 місяці тому +1

    Is there anyway that I can talk to you ? I will be very happy

  • @lianeisme
    @lianeisme 9 місяців тому +1

    I have Er- her2 positive stage 4 cancer is there anything for me yet

  • @marionraine3703
    @marionraine3703 9 місяців тому +1

    Dear Dr Liz
    Im in such a quandary..
    On Fasoldex 2 years
    Then change dr the about a yr ( must check) on equisin
    Horrendous joingg ,bone pain...
    Fingers feet etc
    Was about 12 mm slow groing 2019.....no gland involved
    Have chronic backache anway
    But dehabilitating scare to go off plus oncologist would obviously refuse..got sick in the beginning on tamoxifen (doc says equisin least side effects..
    Where next must i grin and bear it..ps on anti depressent stuff day and night
    Put on a heck a lot of weight. Plus hair thinning
    Is this my life now..69 yrs old
    Love marion❤🎉
    Ps if i went ont anti dep i would perhaps have not gone through torture of not sleeping and drenched at night...(Who knows. Oerhays timing was wrong with the faslodex??and anti deps and anti anxiety meds??

  • @cassieoz1702
    @cassieoz1702 10 місяців тому +6

    GREAT but bugga! Too late for me - I've 'devolved' to triple negative 🥴

    • @clairebeever3038
      @clairebeever3038 10 місяців тому +5

      Mine was triple negative it’s come back but it’s estrogen and progesterone positive now and has spread I hope your doing ok ❤

    • @cassieoz1702
      @cassieoz1702 10 місяців тому +4

      @clairebeever3038 not really 🥴. Facing palliative treatment next week

    • @kathleenbrown6734
      @kathleenbrown6734 9 місяців тому

      @@cassieoz1702so sorry. wish you better life.

    • @carolvalentine9223
      @carolvalentine9223 9 місяців тому +1

      What is palliative treatments?

    • @cassieoz1702
      @cassieoz1702 9 місяців тому

      @@carolvalentine9223 treatments aimed a making me comfortable and, possibly, buying a bit more time. In my case that's radiotherapy and more IV chemo

  • @iconic1758
    @iconic1758 3 місяці тому +3

    Any phyllodes breast tumor patient here or p53 mutant cancer

    • @AliXadyGus
      @AliXadyGus 3 місяці тому +2

      Yeah me, got my results on Thursday. Borderline - 8 mitotic figures counted per 10 high powerfields (8/10)... Awaiting a few Dr's unanimous decision regarding treatment tomorrow. Had Lumpectomy on 2 October but they initially thought it was a Fibroadenoma considering that Phyllodes tumors are so rare?

    • @iconic1758
      @iconic1758 3 місяці тому +1

      Are you into alternative treatments like fenbendazole ivermectin?....

    • @iconic1758
      @iconic1758 3 місяці тому +1

      .. we'll discuss the treatment options available there... My
      p
      O
      S
      T
      I have enlisted some supplements there
      How terrible this UA-cam is .. I can't send a simple message here...

    • @iconic1758
      @iconic1758 3 місяці тому +1

      My mother was operated last yr for bilateral borderline Phyllodes with 9/10 hpf mitotic count.. what's your age...

    • @AliXadyGus
      @AliXadyGus 2 місяці тому +2

      @iconic1758 I am very new to this and unsure. Dr's meeting did not happen yesterday and they will only decide on treatment next week Tuesday...

  • @marionraine3703
    @marionraine3703 9 місяців тому +1

    Ps dr (marion)forgot to mention Luminal A
    🤗

  • @rkjjo
    @rkjjo 10 місяців тому +1

    My wife just started AI yesterday

  • @phyllisnoddin6532
    @phyllisnoddin6532 13 днів тому

    Please someone, somewhere find something better than these aromatase inhibitors.

  • @rachelstrahan2486
    @rachelstrahan2486 10 місяців тому +1

    👍

  • @ruudhop
    @ruudhop 9 місяців тому +2

    Nice
    But there is already existing a generic medicin that clean the whole body and you can repeat every 3 years
    This medicin exists 48 years and cheap
    But pharma needs $$$

    • @laradiantrr9357
      @laradiantrr9357 9 місяців тому +2

      Hi, Please could you share ...What medicine are you referring to ?

    • @ruudhop
      @ruudhop 9 місяців тому

      @@laradiantrr9357
      Google on Ivermectin and cancer
      Also CBD oil and cancer
      I do both for myself.
      CBD cured pancreas in 9 weeks but now Ivermectin for my brain problem.
      Understand that to breakthrough the cellwands is only needed and then your T-cells from your immunesystem clean your body.
      Depending on the type of cancer they break the cellwands.

    • @ruudhop
      @ruudhop 9 місяців тому

      Google on Ivermectin and CBD oil
      With CBD oil i cured my pancreas cancer in 9 weeks
      Now i use Ivermectin for my brain problem.
      Both breakthrough the cellwands and then the T-cells clean the body.

    • @jahlin4250
      @jahlin4250 8 місяців тому +1

      @@laradiantrr9357 It's just nonsense.

  • @lisa-eg8nx
    @lisa-eg8nx 10 місяців тому

    🎉🎉🎉🎉

  • @ellen9579
    @ellen9579 Місяць тому

    🥀🥀💛🥀🥀💛🥀🥀💛🥀🥀

  • @beverlyanderson347
    @beverlyanderson347 14 днів тому

    Nothing new here it's all Hype because They don't want a cancer cure or They would be out of a job!

  • @anneherman6745
    @anneherman6745 10 місяців тому

    💙🐬