Breast Cancer Breakthrough - Targeting Sleeping Breast Cancer Cells || Dr Liz O'Riordan

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  • Опубліковано 25 бер 2024
  • Breast Cancer Breakthrough - Targeting Sleeping Breast Cancer Cells || Dr Liz O'Riordan
    Breaking News - Scientists at the Institute of Cancer Research have discovered a way to wake up sleeping ER positive breast cancer cells and potentially prevent a late recurrence!
    The research was led by Professor Luca Magnani, Professor of Epigentic Plasticity at the ICR and I was lucky enough to be able to interview him today to tell me all about it
    @ICR_London
    👉This is the link to the research summary
    www.icr.ac.uk/news-archive/re...
    ♻️You can read the full paper here
    aacrjournals.org/cancerdiscov...
    ✅In this groundbreaking UA-cam video, we delve into the latest breakthrough in breast cancer research: targeting sleeping breast cancer cells. Join us as we explore the cutting-edge techniques and innovative strategies that scientists are using to awaken and target these dormant cancer cells. Discover how this breakthrough could revolutionize breast cancer treatment and improve patient outcomes. Stay informed and empowered by watching this informative video that sheds light on the promising advancements in the fight against breast cancer.
    _______________________________________________________________
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    _______________________________________________________________
    Thank you for watching
    Please like, comment, subscribe, and hit the bell 🔔 so you never miss any videos!
    👉Subscribe to our channel: / @drlizoriordan
    #BreastCancerResearch #CancerBreakthrough #TargetingDormantCells #MedicalBreakthrough
  • Наука та технологія

КОМЕНТАРІ • 92

  • @deborahbizzell1989
    @deborahbizzell1989 Місяць тому +23

    Great news.This happened to me a couple of times.I thought it wasn't coming back,but after 12 yrs.it did,and after 11 yrs.it returned again.I hope to God that this will help us all affected by breast cancer.😊

  • @goldentarot3914
    @goldentarot3914 Місяць тому +32

    I’m stage 4 Metastic breast cancer to my bones got diagnosed 18 months ago and I’m hoping that any new treatments will come along to help me and others who have to live with this. Thanks for the updates. Stay positive everyone

    • @lanebashford3982
      @lanebashford3982 Місяць тому +7

      You and I share the same diagnosis. My cancer spread to my spine, ribs, arm and lung. I'm 3 years since diagnosis and doing well on Verzenio and Letrozole. Other than fatigue, I'm doing well and pretty much without pain or other problems. Eating and sleeping well. Hope you are doing fine, too.

    • @suegray6284
      @suegray6284 Місяць тому +6

      I had no idea my aggressive breast cancer would return after 12 years, I’m gutted to know I went through so much treatment but never truly got rid of it…I’ve now had 3 operations, 8 months of chemo, 31 days of radiation and I’m on ribocyclib and letrozole. Every day is a bonus. Apart from being a bit more tired I am able to do most things I did before treatment including an 18 mile walk to raise money for cancer research last year. I hope the new research can produce therapies that will help us 🙏🏻🙏🏻🙏🏻

    • @radhanaidu9979
      @radhanaidu9979 Місяць тому

      ​@@lanebashford3982 hi I am struggling with stage 4 breast cancer and spine mets with pain, how are you coping?

    • @ninanicefrench1013
      @ninanicefrench1013 Місяць тому +4

      Seems like I’m reading my story same dx. I’m on RIbo and letrozole my joints hurt so bad. Had a double mastectomy

    • @marlismueller4496
      @marlismueller4496 29 днів тому +5

      How do you deal with the fear of dying soon? I am asking because I feel very traumatized.

  • @jpb1085
    @jpb1085 Місяць тому +10

    Thank you! Late recurrence is something that deserves more attention now that, thankfully, so many of us are surviving our initial cancer.

  • @theresahickscch6581
    @theresahickscch6581 Місяць тому +19

    That’s me - 23 years with radiation and tamoxifen on board. I thought I was done; obviously wrong. New theories and research bring good news for us. Thank you Dr. Liz for sharing the latest research.

    • @gena.9564
      @gena.9564 Місяць тому +3

      What was your tumor type? 😢

    • @theresahickscch6581
      @theresahickscch6581 24 дні тому

      @@gena.9564 HR positive, HER2 negative, no lymph nodes involved

  • @RovingReader
    @RovingReader Місяць тому +11

    This is 100% my mom- 17 years! Thanks so so much!

  • @user-xz7zf8ht7q
    @user-xz7zf8ht7q Місяць тому +11

    I had read about this research too, but they say it will take 5 to 6 years for these medicines, if they can start covid vaccine for energency use, i wonder why these medicines should take so long.

    • @beautifulvictory9683
      @beautifulvictory9683 25 днів тому

      Keep in mind, the C0vid v@xine was released on an experimental basis as well as emergency. The side effects are coming home to roost & are being discovered well after. There is no recourse for those that experience the said side effects. That's why it takes so long, to work out the potential issues.

    • @HL-qv3yd
      @HL-qv3yd 15 днів тому

      That exactly my question too

  • @HL-qv3yd
    @HL-qv3yd Місяць тому +2

    Thank you dr Liz, following up and informing us, very great full.

  • @gemmac3371
    @gemmac3371 Місяць тому +10

    Thank you for the video, I was stressing about this so much as this is the type of cancer I had. So glad you are around for this amazing information. ❤

  • @kdclothes
    @kdclothes Місяць тому +6

    Thank you for this video. this is my case. I just healed from my surgery.

  • @mfinn7880
    @mfinn7880 Місяць тому +1

    Thanks, Dr. Liz, I so trust your brilliant wee videos, 😀 thanks so much 🙏 😀

  • @melindavalle173
    @melindavalle173 Місяць тому +3

    Thank you, thank you, thank you! ❤❤❤

  • @user-gq5cn6wv9l
    @user-gq5cn6wv9l Місяць тому +3

    Thank you so much, Liz! You are keeping informed us so extremely well...An amazing finding for future therapies. Not for all of us perhaps - my recurrence came after eight years - , but for many women to come.

  • @robbar42
    @robbar42 23 дні тому

    thank you very much for sharing. This is a positive boost of emotional energy

  • @bcourtney4024
    @bcourtney4024 Місяць тому +1

    So fabulous.❤

  • @elainespeirs7800
    @elainespeirs7800 26 днів тому +1

    Since im not even at year 1 cancer free this us very encouraging news. I hope new treatments come soon

  • @KTen-cm6wx
    @KTen-cm6wx Місяць тому +4

    Dr. O’Riordan, I love you for the information and education that you share with us. Where can I find in the US the groovy kool frames you wear. Happy Easter ❤

  • @Debilee16
    @Debilee16 Місяць тому +10

    This is reassuring, I had her2 positive breast cancer ,was caught early stages 2 ,had mastectomy, but was told I didn't need Radiotherapy not sure why ?I'm on kadcyla now got 4 more to go and given Exemestane inhibitors but finding the side effects quite bad ,real bad bone pain in hands ,arms very tired ,I have to keep taking a break from them ,I no alot of women stop taking these ,but I'm scared the cancer might come back so hearing this if it comes off gives us hope 🙏

    • @susanelizabeth5841
      @susanelizabeth5841 Місяць тому +1

      Your experience is similar to mine - also no radiation. Could you please share your stage and Oncotype DX score?
      Thank you.

    • @endlessdelirium213
      @endlessdelirium213 Місяць тому +2

      I had to come off Exemestane due to the pain in my joints and legs. I've managed better since the hospital put me on Tamoxifen

    • @MC37138
      @MC37138 Місяць тому

      If the cancer does not reach lymph nodes….then radiation is not needed…that is what I was told….

    • @angieposton8377
      @angieposton8377 Місяць тому

      I’m on Tamoxifen and have a few night sweats but doing great on it.@@endlessdelirium213

    • @lisatorigian837
      @lisatorigian837 Місяць тому

      Who gets the Exemetanse ?

  • @monikaengel5515
    @monikaengel5515 Місяць тому +5

    Im almost 5 years survivor estrogen positive bc continues anastrozole with zokadex injection i hope never ever will had recurrence but its soo hard 😢live in fears if anastrazole keep cancer away i will continues as long as i needed but side effects not great stiff joints mornings ,fatigue,dry skin sleep issue but continues fasting eating clean and daily 4 miles and weights 💪

  • @erika_koos
    @erika_koos Місяць тому +1

    Hello Dr. Liz! Thank you so much for sharing these exciting news. I know it might be early to ask but do you see it possible that patients who are already under anti-hormone treatment can also benefit from this discovery? Dr. Magnani mentioned that patients would receive this treatment from the early days of starting the aromatase inhibitors.

  • @youownawebsite
    @youownawebsite 27 днів тому +1

    yes please clarify and correct your info about hormone blockers' killing ' when they dont as its confusing

  • @Sarappreciates
    @Sarappreciates 21 день тому +1

    Dr Liz, thank you! My mother died of pneumonia in February weeks before the worst PET scan of my cancer case so far. I'll begin a new therapy to treat MBC with mets in lungs and bones: TRUQAP instead of Ibrance now. Everything in my treatment is changing except for Lupron. My bone mets will now be treated with the infusions of Zometa to prevent spinal fractures. Rather than oral Arimidex or Letrozole, I'll be getting Faslodex injections, one in each hip every month, then another injection of Lupron. It feels like so much to take in all at once. I don't know how to keep my brain from exploding! 🤯 One day at a time, I guess.

  • @brianmurray9405
    @brianmurray9405 Місяць тому +2

    Amazing !! So does it work on mets disease anyway it’s good news

  • @DCGreenZone
    @DCGreenZone 17 днів тому +2

    The City of Hope is adding Ivermectin to TNBC treatment, University at Glasgow is adding Mebendazole to Docetaxel for PC, Dr. Marc-Eric Halatsch is using Itraconazole in a 9 repurposed drug protocol for Glioma and Glioblastoma. Dr Tom Rogers YT video on Artemisisin and Fenbendazole has some comments you may be interested in.

    • @laradiantrr9357
      @laradiantrr9357 6 днів тому +1

      That's great to hear that City of Hope is adding Iver. into their treatment possibilities! Do you work there or know anyone there so you are knowing this info. as fact?

    • @DCGreenZone
      @DCGreenZone 6 днів тому

      @@laradiantrr9357 Sorry, I don't know anyone there, I don't work there... but I do Google for the latest information on the Azoles and Avermectins. Check out University at Glasgow, PC and Mebendazole for another treat. The City of Hope web announcement is there if you search for it.

    • @DCGreenZone
      @DCGreenZone 5 днів тому

      @@laradiantrr9357 I answered you and my response was evaporated. Use Google to find University of Glasgow and Mebendazole, City of Hope and Ivermectin. Let's see if I broke any rules this time.

    • @DCGreenZone
      @DCGreenZone 5 днів тому

      @@laradiantrr9357 Unable to respond. Ministry of truth is at it again.

  • @HL-qv3yd
    @HL-qv3yd Місяць тому +3

    I hope they discover cure for this cancers very sooner.

  • @Rosalicious297
    @Rosalicious297 Місяць тому +2

    Do we know the percentage of Er+ primaries that go on to metastasise? This is fantastic news for women in the future. Thank you to the wonderful research scientists!

    • @bosslady5163
      @bosslady5163 28 днів тому +1

      I read somewhere that about 30% 😢

  • @claudiacicesa
    @claudiacicesa Місяць тому +2

    Thank you for sharing this great news with us. Hope studies clinical fase I-IV go right and soon we have more options to treat/avoid properly hormonal breast câncer recurence.

  • @earthwalker8277
    @earthwalker8277 Місяць тому +2

    Does this potentially apply to both ER+ HER2- and triple positive breast cancers?

  • @naheedakhtar4815
    @naheedakhtar4815 17 днів тому

    Hi i was diagnosed with breast cancer stange 2grade 3 her 2 positive i only had 2 chemo cycles whale doong my resuch i stop my chemotherapy due to sideaffects i had sugery but all so refferd radiotherapy its been 6 weeks i am on tamoxifen i am thinking to give up due to sideaffects in future i stll haven't recovered from chemo yet it has been 6 months only by having 2 chemo cycles just imagine if i had all 6 .
    Can you advice me what about if i took tamoxifen twice a week to avoid sideaffects do you think am i doing the right thing or take medicine 1 day and miss 1 day .
    Or if i completely stop tamoxifen what can i do instead

  • @jahlin4250
    @jahlin4250 6 днів тому

    Do breast cancer cells enter this sleep mode if one is treated with Tamoxifen?

  • @Katsem
    @Katsem Місяць тому +5

    I’ve had hormone sensitive breast cancer twice, the second time after 7.5 years. I was told by my oncologist that my aromatase inhibitor did NOT kill cancer cells, but changed the environment so the chance of cancer cells growing was reduced. But I think what’s been said here is that aromatase inhibitors actually kill the cells, aside from these sleeper cells. I’m pretty confused.

    • @missw2
      @missw2 Місяць тому

      Your oncologist is correct. AI's work by blocking the conversion of androgen to oestogen in the body thereby removing a source of 'fuel' for an oestrogen-driven cancer to grow.

    • @youownawebsite
      @youownawebsite 27 днів тому +1

      Yes Ive asked Liz to please clarify and correct her info about hormone blockers' killing ' as its confusing

    • @beautifulvictory9683
      @beautifulvictory9683 25 днів тому +1

      I was under the impression that the environment changed as well. Not kill so to speak. My Onco did say an aromatase inhibitor is more effective than Tamoxifem. 🤔

  • @cynthiayee5116
    @cynthiayee5116 Місяць тому +5

    I have just saterted 6 month tamoxifen ...For 5 years

    • @mfinn7880
      @mfinn7880 Місяць тому

      Thanks for sharing that 👍 bless you

  • @hananezzat7973
    @hananezzat7973 28 днів тому

    My mother has here disease recurrence both breas each five years apart and recurring in her right side twice why dose that happend very close

  • @vanessacampbell4655
    @vanessacampbell4655 26 днів тому +2

    Does this apply to metastasized breast cancer also? I know it's just the beginning stages of the research but if the cancer is already stage 4 and in other parts of the body, will this help those people also?

    • @HL-qv3yd
      @HL-qv3yd 15 днів тому

      I like to know answer this question too

  • @lianeisme
    @lianeisme Місяць тому

    I have Er- her2 positive stage 4 cancer is there anything for me yet

  • @cassieoz1702
    @cassieoz1702 Місяць тому +4

    GREAT but bugga! Too late for me - I've 'devolved' to triple negative 🥴

    • @clairebeever3038
      @clairebeever3038 Місяць тому +3

      Mine was triple negative it’s come back but it’s estrogen and progesterone positive now and has spread I hope your doing ok ❤

    • @cassieoz1702
      @cassieoz1702 Місяць тому +2

      @clairebeever3038 not really 🥴. Facing palliative treatment next week

    • @kathleenbrown6734
      @kathleenbrown6734 Місяць тому

      @@cassieoz1702so sorry. wish you better life.

    • @carolvalentine9223
      @carolvalentine9223 29 днів тому

      What is palliative treatments?

    • @cassieoz1702
      @cassieoz1702 29 днів тому

      @@carolvalentine9223 treatments aimed a making me comfortable and, possibly, buying a bit more time. In my case that's radiotherapy and more IV chemo

  • @marionraine3703
    @marionraine3703 20 днів тому

    Ps dr (marion)forgot to mention Luminal A
    🤗

  • @rachelstrahan2486
    @rachelstrahan2486 Місяць тому +1

    👍

  • @rkjjo
    @rkjjo Місяць тому

    My wife just started AI yesterday

  • @lisa-eg8nx
    @lisa-eg8nx Місяць тому

    🎉🎉🎉🎉

  • @anneherman6745
    @anneherman6745 Місяць тому

    💙🐬

  • @marionraine3703
    @marionraine3703 20 днів тому

    Dear Dr Liz
    Im in such a quandary..
    On Fasoldex 2 years
    Then change dr the about a yr ( must check) on equisin
    Horrendous joingg ,bone pain...
    Fingers feet etc
    Was about 12 mm slow groing 2019.....no gland involved
    Have chronic backache anway
    But dehabilitating scare to go off plus oncologist would obviously refuse..got sick in the beginning on tamoxifen (doc says equisin least side effects..
    Where next must i grin and bear it..ps on anti depressent stuff day and night
    Put on a heck a lot of weight. Plus hair thinning
    Is this my life now..69 yrs old
    Love marion❤🎉
    Ps if i went ont anti dep i would perhaps have not gone through torture of not sleeping and drenched at night...(Who knows. Oerhays timing was wrong with the faslodex??and anti deps and anti anxiety meds??

  • @ruudhop
    @ruudhop 21 день тому +1

    Nice
    But there is already existing a generic medicin that clean the whole body and you can repeat every 3 years
    This medicin exists 48 years and cheap
    But pharma needs $$$

    • @laradiantrr9357
      @laradiantrr9357 17 днів тому

      Hi, Please could you share ...What medicine are you referring to ?

    • @ruudhop
      @ruudhop 15 днів тому

      @@laradiantrr9357
      Google on Ivermectin and cancer
      Also CBD oil and cancer
      I do both for myself.
      CBD cured pancreas in 9 weeks but now Ivermectin for my brain problem.
      Understand that to breakthrough the cellwands is only needed and then your T-cells from your immunesystem clean your body.
      Depending on the type of cancer they break the cellwands.

    • @ruudhop
      @ruudhop 15 днів тому

      Google on Ivermectin and CBD oil
      With CBD oil i cured my pancreas cancer in 9 weeks
      Now i use Ivermectin for my brain problem.
      Both breakthrough the cellwands and then the T-cells clean the body.

    • @jahlin4250
      @jahlin4250 6 днів тому

      @@laradiantrr9357 It's just nonsense.