The 4 Most Impactful Peptides for my Chronic Pain

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  • Опубліковано 2 лют 2025

КОМЕНТАРІ • 123

  • @roberthuffman4599
    @roberthuffman4599 2 дні тому +1

    Excellent info

  • @BetterHumanz
    @BetterHumanz 3 місяці тому +7

    Great video, BPC-157/TB-500/GHK-cu is an awesome combo I have used this many times infact I am right now for some inflamation and skin. :)

  • @patrickllt
    @patrickllt 29 днів тому +3

    Thank you for pointing this video to me. Greatly appreciate it. Why is TB4 not sold anymore?

    • @DrewTimmermansND
      @DrewTimmermansND  29 днів тому

      Thank you! I'm glad you liked it.
      The FDA reclassified the number of amino acids for something to be a 'biologic', which TB4 fell into that category. This is also why hCG cannot be made in a compounding pharmacy anymore

    • @megandowling8746
      @megandowling8746 26 днів тому

      @@DrewTimmermansND
      How much money does the pharmaceutical industry give to the FDA?

    • @DrewTimmermansND
      @DrewTimmermansND  23 дні тому +3

      Too much

  • @truckcraz
    @truckcraz 17 днів тому +2

    Does it help for arthritis pain

    • @DrewTimmermansND
      @DrewTimmermansND  16 днів тому

      Yes it definitely can! On average, 70-80% of patients will see improvements

  • @davidballard4405
    @davidballard4405 2 місяці тому +4

    So what’s a good dose/cycle for injectable bpc for back pain?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      If you watch the full video, I talk about BPC-157 dosing. If you're looking for personalized dosing for your situation, you would need to become a patient as that constitutes medical advice

    • @davidballard4405
      @davidballard4405 2 місяці тому +1

      You gave dose for oral bpc, is the dose the same for subq injections? .5g?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому +1

      Sorry you're right. You can drop it down a bit as the bioavailability is better with injectable. Typically we use 300mcg

    • @davidballard4405
      @davidballard4405 2 місяці тому +1

      @ you’re the man thank you

  • @lerch400block
    @lerch400block 11 днів тому +1

    Would this be the best post shoulder surgery "stack"?

    • @DrewTimmermansND
      @DrewTimmermansND  11 днів тому

      Not necessarily. The best 'stack' is one that is individualized to the patient and to the specific tissues that are causing pain. So for some people these 4 peptides would all be indicated and would be part of a larger stack with vitamins and other nutrients, but not for others

  • @wishbone103
    @wishbone103 18 днів тому +1

    mcg to milliliters?

    • @DrewTimmermansND
      @DrewTimmermansND  18 днів тому

      Depends on what your mcg/mL is of your vial. Search online for peptide calculators and this will help you

  • @Mike-dt1yg
    @Mike-dt1yg 9 днів тому +1

    Do you think tendon fenestration would be enough stimulus for BPC & TB4 to work their magic?

    • @DrewTimmermansND
      @DrewTimmermansND  9 днів тому

      You don't need any mechanical stimulus at all, I just think it works better when there is mechanical stimulus. So yes that would be enough.

  • @JT-un7dc
    @JT-un7dc 18 годин тому

    What's up, Doc? I just subscribed to your channel. I've taken oral BPC-157 with great success. Started with DR seeds, then became DNA now Infiniwell. Do you recommend the delayed or the rapid version of BPC-157? Also, is nasal TB-500 a viable option compared to injectable? As 51 year old skateboarder BPC changed my life repairing my guy and tendons.

  • @thornthorn8879
    @thornthorn8879 Місяць тому +2

    Doc whAt do you Think about kpv peptide ?? Do you use that peptide ???

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому +1

      We have used it a little bit, truthfully not enough for me to give a strong opinion either way

  • @susanvanputten492
    @susanvanputten492 15 днів тому +1

    What was the dosing of injectable bpc 157?

    • @DrewTimmermansND
      @DrewTimmermansND  15 днів тому +1

      We use 300mcg subQ in abdomen once per day at minimum

  • @MotorCityMoto
    @MotorCityMoto 6 днів тому

    What's the best peptide or combo for distal clavicle osteolysis aka weight lifters shoulder?

  • @NoMoreTalkingg
    @NoMoreTalkingg 2 місяці тому +3

    Does bpc 157 heal musculoskeletal injuries better when you’re fasting? When you’re eating a lot of food you tend to build some inflammation in the gut because it’s working hard, and when you take bpc it might target healing the gut when you intentional did it to heal the musculoskeletal injury, so when in a faster state where your gut takes a break it targets the musculoskeletal injury better. Just curious if that’s a thing.

  • @thornthorn8879
    @thornthorn8879 2 місяці тому +2

    Ghk injection or oral form ??

  • @tonywiley9662
    @tonywiley9662 2 місяці тому +2

    Very informative. How long before and after stem cell injections, can you use peptide therapy?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому +1

      We start immediately after!

    • @fritzfontaine7126
      @fritzfontaine7126 2 місяці тому

      @@DrewTimmermansNDdoes one take the BPC WITH SNAC OR WITHOUT FOR DIGESTIVE issues ?? Thanks doc

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      You can't go wrong with either to be honest. Start with 1 month of the original formula (without snac) 500mcg once per day. If you don't see benefits, then try the delayed release.

  • @buffgandhi
    @buffgandhi 3 місяці тому +5

    But you cannot get them from compounding pharmacy anymore

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому

      We thankfully still have access to some of them from one specific pharmacy

    • @kinggeo3165
      @kinggeo3165 3 місяці тому

      @@DrewTimmermansND Is it legal through this specific pharmacy? Is taking it orally somehow more approved then injectables?

  • @brogeybrothers
    @brogeybrothers 2 місяці тому +2

    You say bpc-157 should be used with PT, so when should and how much should be taken orally? I see you advised the infiniwell 250mg original, so should it be taken twice a day?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому +2

      Our normal dosage for oral BPC-157 is 500mcg once per day on an empty stomach. Sometimes we need to double that (500 twice per day). When pairing with PT, we recommend to take it right after PT

  • @susanvanputten492
    @susanvanputten492 12 днів тому

    Doctor will Thymosin TB4 & Thymosin alpha - 1 ever come back on the market and was it pulled because it’s not safe? Thx :)

    • @DrewTimmermansND
      @DrewTimmermansND  12 днів тому +2

      No they were not pulled because they weren't safe. We actually have both of them back from one pharmacy at the moment

    • @susanvanputten492
      @susanvanputten492 12 днів тому +1

      @ thank u! Can you help people with fibrosis from radiation & do you ever do Telehealth for out of State? I’m sure some therapies need to be in person Thx again! I sent ur video to a friend

    • @DrewTimmermansND
      @DrewTimmermansND  12 днів тому

      In order to prescribe peptides patients needs to see me in my office. We have used our regenerative therapies and peptides to help a small number of patients with fibrosis from surgery, yes

  • @bh9262
    @bh9262 Місяць тому +1

    Drew Can I take BPC 157 with amoxacillin? I had a tooth extraction and was prescribed this.

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      There are no known drug interactions with BPC-157

  • @anontablet6304
    @anontablet6304 3 місяці тому +2

    How are patients using cjc/ipamorelin without sourci g from a research chemical company since FDA banned it???

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +3

      We currently don't have access to that specific GH secretagogue, so we are using MK-677

  • @alexwilder9968
    @alexwilder9968 27 днів тому +1

    Is it normal to experience dizziness and hot flashes from BPC-157 without snac?

  • @tonyb282
    @tonyb282 2 місяці тому +2

    Hello great video. I am currently having tendonitis in one of my elbows. I'm currently on trt and will be adding nandrolone with it. I was just given a few vials of bp157. I was waiting for your injectable bp157 protocol. Did I miss it?

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      In the video I discuss the dosing protocol that I used for BPC-157. I also have other full length videos on BPC-157 dosing if you search my channel

  • @whirlwinds2321
    @whirlwinds2321 23 дні тому +1

    I have my BPC-157 but cannot find where to get the TB-500, it is holding me up? Any suggestion on where to get this stuff?

    • @DrewTimmermansND
      @DrewTimmermansND  22 дні тому +1

      If you are working with a physician and can get injectable peptides from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable versions as this would require you to purchase them from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects.

    • @whirlwinds2321
      @whirlwinds2321 22 дні тому +1

      @DrewTimmermansND okay, I actually found a dr. In my city after hearing horror stories.

    • @DrewTimmermansND
      @DrewTimmermansND  22 дні тому

      love it!

  • @artemthetrain14
    @artemthetrain14 3 місяці тому +4

    Have you ever heard of BPC-157 causing a recurrence in shingles? And can you think of why this would be? Does it affect the immune system negatively?

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +1

      We haven't no. My first question is whether you took the oral or the injectable version, and if injectable, where you got it from

    • @artemthetrain14
      @artemthetrain14 3 місяці тому +2

      @@DrewTimmermansND I haven't taken. I was planning on oral from InfiniWell, but have just heard a few anecdotes (not sure of what form they took).
      I was planning on taking the plunge but the stories were enough to scare me off for now... I had shingles like 20 years ago

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +2

      We haven't seen any cases of shingles coming out with using legit oral or legit compounded injectable. Gonna guess that those you heard about used research chemical peptides, which are laden with endotoxins which stimulate the immune system in a negative way and can worsen old infections

    • @badbaddolemike
      @badbaddolemike 3 місяці тому +1

      Yes, I was curious about this as well. My father recently had a stroke, and I was looking into bpc 157 for stroke recovery. While reading about bpc 157 and learning about what it can do to the nervous system, I thought about my Mom that had a shingles outbreak a few years back, but every once in a while she feels "nerve pain" on her face/forehead where her last shingles rash was. I thought about the bpc 157 to potentially help heal her nerves, and that lead me to a reddit page(r/shingles, if I remember right) where someone posted everything they were taking as something had just triggered a shingles outbreak. Looking at their supplement list another redditor made the connection of bpc 157 and shingles. They said that they had an outbreak about a week after starting the bpc 157. Then the original poster said that their outbreak started about a week after starting bpc 157 too. Then another person replied saying the same thing happened to them. I believe it was around 4 or 5 people that ended up responding saying the same thing happened to them, and that was in just 1 reddit thread. I was curious on what may be causing this, but I just read the doctors latest response, so I guess there is no mechanism of action of the bpc 157 on the immune system that would cause an outbreak thats been identified yet???
      Also, considering that bpc 157 induces the release of serotonin in specific areas of the brain and influences serotonergic and dopaminergic systems, is it safe to take bpc 157 and methylene blue at the same time? I dont mean dosing together, but just to take on the same day. I want my Dad to take everything he can to aid in his recovery. Sorry this is so long. Thank you for any info you can provide.
      *edit- removed some emojis that were randomly in the middle of a word

    • @artemthetrain14
      @artemthetrain14 3 місяці тому +1

      @@badbaddolemike yeah we must have been on the exact same post. It's tough because it's like these are just a few stories, but to be fair most of the evidence around BPC 157 is anecdotal anyway. Shingles recurrence usually happens in people with suppressed immune systems so I'm wondering if BPC has any mechanism that does that. I can't really find anything

  • @LionLohman
    @LionLohman 3 місяці тому +2

    I really appreciate the video. You definitely know what you're talking about. Where online can I purchase TB500 1. in oral and 2. in injectable? Thank you.

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      TB500 is not stable in the stomach and it degrades, so no oral version available.
      If you are working with a physician and can get injectable T500 from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable version as this would require you to purchase T500 from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects.

  • @vinniestonewood1
    @vinniestonewood1 2 місяці тому +1

    Love your videos and find them so informative.
    I am planning on doing a BPC and TB500 stack for some inflammatory issues and have TB4 fragment 17-23. My question is regarding how this effects dosage? My plan was to inject 2.5mg twice a week but am wondering if the fragment changes things in regards to the half life? I'm super confused on the fragment part. Thanks so much!

  • @user-wv5gv3dw5u
    @user-wv5gv3dw5u 3 місяці тому +3

    Im male with chronic inflammation (post Covid/Lyme) 5 years of pelvic floor dysfunction. And now 2 years of pudendal neuralgia. Extreme testicular pain and groin numbness. Doctors have told me theres nothing to do now but burn my nerves so I at least wont be in pain. Im 27, this seems way too permanant for my age.
    What are the chances peptides or any sort of regenerative medicine can help or even fix my damage/pain in my pelvic area?

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому

      It's very difficult for me to say without seeing you in my office for a medical workup. Our approaches to pudendal neuralgia are effective in about 80% of patients though. If you'd like to explore this, please reach out to my clinic regenerativeperformance.com

  • @cybermania01
    @cybermania01 Місяць тому +1

    Please can you tell me where to buy the BPC-157 from a reputable place. Amazon have 95% fake BPC...

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      We use the BPC-157 capsules from InfiniWell as they use the arginate salt which is the better form of BPC. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link. There are three options for BPC-157, and truthfully all of them work well!

  • @vineetchopra6116
    @vineetchopra6116 Місяць тому +1

    How to ensure that these peptides are genuine? Any tried and tested brand recommendations?

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      If you are working with a physician and can get injectable peptides from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable versions as this would require you to purchase them from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects.
      For oral BPC (which works just as well as the injectable in most patients), we use the BPC-157 capsules from InfiniWell as they use the arginate salt which is the better form of BPC. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link. There are three options for BPC-157, the Rapid, the Delayed, and the Original Formula. Currently, I'm not sure if any of them work that much better as long as you're getting the arginate salt (which the InfiniWell brand uses) and you're taking 500mcg once per day. There is a small study that InfiniWell did on chronic pain using the Delayed Pro 500mcg twice per day on an empty stomach and it performed very well (basically what I would see when we used the Original Formula). So I don't know how much the difference in the forms really matters.

    • @vineetchopra6116
      @vineetchopra6116 Місяць тому

      What would you advise on how long should a person take this orally and how often does this need to be periodically repeated?

    • @vineetchopra6116
      @vineetchopra6116 Місяць тому

      @ Thank you for your advice. Need further help on how to reverse the damage caused by these endotoxins?

  • @jessefowler1303
    @jessefowler1303 Місяць тому

    I injured my plantar fascia from doing heavy calf raises about a year ago. I'm thinking about BPC-157 injections after trying all conservative recovery methods. Do you think BPC could help me? If so, should I inject in my heel fat pad or near the arch of the foot?

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      Not sure if it will help you specifically. We find it helps about 70-80% of people for chronic pain (regardless if it's the injectable or oral version).
      If you are working with a physician and can get injectable BPC-157 from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable version as this would require you to purchase BPC-157 from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects. Instead of using injectable, we then recommend using an oral arginate salt. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. If you want a discount code, we have one for our patients on our website regenerativeperformance.com/supplements. Once on that website, click the InfiniWell link. There are three options for BPC-157, and truthfully all of them work well!
      If you decide to risk it with injections, don't need to inject near the site of injury, you just need to inject subcutaneously into the abdomen as it goes systemic.

  • @HOOVER783-ny7ej
    @HOOVER783-ny7ej 3 місяці тому +2

    Are peptides a Rx that must be written by a Physician? If not I’d love to try them

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому

      If you are working with a physician and can get injectable BPC-157 from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable version as this would require you to purchase BPC-157 from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects. Instead of using injectable, we then recommend using an oral arginate salt. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. If you want a discount code, we have one for our patients on our website regenerativeperformance.com/supplements. Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157 Original 250mcg'. This is the version that does not have SNAC, which we find works better.

  • @silent_anon404
    @silent_anon404 Місяць тому +1

    First of all, great video and I love your channel. My question is: do you have any suggestions regarding peptides for nerve repair, following viral infection (Covid in my case)?
    I already know about BPC and TB500, but what about ARA-290?

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      We only used ARA290 a little bit many years ago because the FDA took our legitimate sources away. So unfortunately we have less options with nerve repair

  • @artemthetrain14
    @artemthetrain14 2 місяці тому +3

    Have you seen good results with bone fractures and bpc157?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      Any time we have had patients with a bone fracture, we use many different supplements and peptides, not just a single one like BPC-157.
      Here is a protocol that we used on a patient who had a metacarpal fracture: 1drv.ms/b/s!AgzRxlIX-4ydgrxil6CSaopQiOB52A?e=w9Ecal
      Each patient protocol is unique, but this was hers.
      This protocol resulted in her orthopedic surgeon being shocked at how quickly she was healing, to the point that the surgeon had to double check the dates of the xrays because he didn't believe it!

  • @tydodge
    @tydodge Місяць тому

    I was told I'd have to live with plantar fasciitis, my job involves walking. About two weeks 5mg BPC-157/TB-500 it seems to have gone away. Makes me wonder what it would do for an inflammatory disease like asthma?

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      LOVE hearing this!
      Unfortunately I only work with MSK issues, so I have no experience using it in asthma or other lung conditions. However, just because it reduces inflammation in connective tissues like the plantar fascia doesn't mean it works on all tissues that are inflamed.

    • @jimmypruvot859
      @jimmypruvot859 Місяць тому

      Did you use injection subcutaneous on belly fat to help treat the plantar fascitiis? What was your dosage ? I have it for one year, don't know what to do to get rid of it and received bpc157 yesterday - but I have no tb500

    • @tydodge
      @tydodge Місяць тому

      @@jimmypruvot859 Look up peptide dosage calculator.

  • @94121sf
    @94121sf 29 днів тому

    Greetings and Happy New Year,
    Starting a Lupron Rx for 90 days (Reduces my testosterone to ZERO...)
    Will mk677 (hgh) continue to help maintain my muscles with continued workouts ? My research indicates that mk677 steers clear of the testicular pathways and only initiates the HGH circuit...
    Thanks in advance

  • @lisadetav9319
    @lisadetav9319 3 місяці тому +10

    Was wondering what reputable company’s sells bpc 157 in capsules. Any recommendations?

    • @RaulEdu33
      @RaulEdu33 3 місяці тому +7

      I've tried the BPC Capsules from Limitless Life Nootropics, I felt great gut and digestion benefits, and my neuropathy symptoms improved for about 3-4 months after finishing the treatment. I don't have experience with other brands.

    • @sncnutrition7118
      @sncnutrition7118 3 місяці тому

      Infiniwell

    • @sixtyinsix
      @sixtyinsix 3 місяці тому +4

      Just off my first round of Peptide Sciences Repair and Recovery (BPC-157 Arginate & Thymosin Beta-4 Fragment).
      Took the first 30 pills every other day per Huberman.
      Unnoticeable healing results (I attribute this as too small a dose frequency for my size & multiple injuries) so upped dosage frequency to one pill per day for the last 30 (dosage as mentioned in this video).
      This kick started what felt like a normal healing progression as opposed to lagging healing (possibly overwhelmed).
      Waiting a month, then starting a second round.
      First 30 pills one a day, last 30 pills twice a day.
      I'm mid 50's male, 5'9", 225#, muscular 20% body fat.
      Hit and run auto accident (pedestrian victim) involving fractured clavicle & 2 ribs, soft tissue damage chest and back, etc.

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +7

      We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157 Original 250mcg'. This is the version that does not have SNAC, which we find works better.

    • @trey2735
      @trey2735 3 місяці тому +1

      I watched your BPC video from 5 years ago. It seems that you more so recommended oral for gut issues back then. After utilizing it in patients the past 5 years using the oral form for connective tissue healing, would you moreso say now that you could receive close to similar benefits using the oral form for connective tissue healing rather than injection? @@DrewTimmermansND

  • @angelabiggins5105
    @angelabiggins5105 3 місяці тому +3

    Would like tour researched opinion, where to purchase quality products yo take orally.
    Husband is on injections for herniated disc, $625.00 one month bpc-157b-500 combo cost.
    Bought somw oills whick i am taking and receiving benefits.
    Your comments previous video there is no diffeence in the benefits orally or injected.
    Would like to purchase affordable but reputable products that are guaranteed what is in the bottle actually is.
    Thank you so much for your videos!
    Please let me know😁

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157 Original 250mcg'. This is the version that does not have SNAC, which we find works better.
      Unfortunately TB500 is not available in oral form.

  • @siwangliu3103
    @siwangliu3103 2 місяці тому +2

    Doc how to become your patient ?

    • @DrewTimmermansND
      @DrewTimmermansND  2 місяці тому

      Reach out to my clinic! regenerativeperformance.com

  • @stevenbartlett9166
    @stevenbartlett9166 Місяць тому

    You didn't say how many ml to inject of the bpc-157

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому +1

      The 500mcg oral equivalent is about 300mcg for subcutaneous injection.

  • @carolmartin3028
    @carolmartin3028 Місяць тому +2

    I have not gotten any relief from 157

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому

      I'm sorry to hear that. Which brand are you using, and what dosage?

  • @nmoney000
    @nmoney000 Місяць тому +2

    On BPC for joint repair from infiniwell, do you recommend the rapid or original? Wasn't sure if the added SNAC compound was necessary or wanted. Also, would you recommend tablets or capsules? Thanks

    • @DrewTimmermansND
      @DrewTimmermansND  29 днів тому

      There are three options for BPC-157, the Rapid, the Delayed, and the Original Formula. Currently, I'm not sure if any of them work that much better as long as you're getting the arginate salt (which the InfiniWell brand uses) and you're taking 500mcg once per day. There is a small study that InfiniWell did on chronic pain using the Delayed Pro 500mcg twice per day on an empty stomach and it performed very well (basically what I would see when we used the Original Formula). So I don't know how much the difference in the forms really matters.
      We only use the capsules, so I can't comment on efficacy of the tablets. Again, not sure it matters

  • @unclecarney1526
    @unclecarney1526 3 місяці тому +3

    I really dont want to inject everyday, its hard enough every 5days on trt.

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +1

      Oral BPC-157 arginate salt works just as good as the injectable in most people. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157 Original 250mcg'. This is the version that does not have SNAC, which we find works better.
      As for the other products, the GHK-Cu comes in a topical for skin (also on the InfiniWell site), which does have some systemic absorption, it's just not as much as the injectable. I haven't seen enough research yet for the absorption of TB4 frag, so we don't really recommend it. Then for GH secretagogues, you're really only left with MK-677 which is orally bioavailable.

    • @davidballard4405
      @davidballard4405 2 місяці тому

      Sub Q isn’t so hard

    • @paulhewson6302
      @paulhewson6302 Місяць тому

      Well that's on you then 🤷

  • @paaaatrika
    @paaaatrika 3 місяці тому +3

    What do you mean TB4 is no longer available? I just got some BPC-157/TB4 mix just a few weeks ago.

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +1

      TB4 is no longer available through compounding pharmacies, which is the only place we recommend to get injectables. Injectable peptides from research chemical websites (where you buy on your own from a website) are notoriously contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects.

  • @youonlyliveonce6000
    @youonlyliveonce6000 3 місяці тому +2

    The suppression of natural GH production can lead to several consequences:
    1. Dependence on exogenous GH: The body may become reliant on external sources of GH to maintain normal physiological functions.
    2. Altered GH pulsatility: Natural GH secretion occurs in pulses, which may be disrupted by continuous exogenous GH administration.
    3. Potential long-term effects: Prolonged suppression of endogenous GH production may lead to atrophy of the pituitary gland’s GH-producing cells.
    4. Metabolic changes: Altered GH levels can affect metabolism, potentially leading to changes in body composition, insulin sensitivity, and lipid profiles.
    5. Risk of side effects: Exogenous GH administration can cause side effects such as fluid retention, joint pain, and carpal tunnel syndrome.
    6. Potential for abuse: In non-medical settings, the use of GH as a performance-enhancing drug can lead to health risks and ethical concerns

    • @DrewTimmermansND
      @DrewTimmermansND  3 місяці тому +4

      All correct. This is why we don't use GH, but rather GH secretagogues which stimulate the release of your own GH and do not suppress natural GH production

  • @loopba
    @loopba Місяць тому +2

    really unnecessary to dose twice daily. Especially GH secretagogues. Sounds like a non-science based upsell

    • @DrewTimmermansND
      @DrewTimmermansND  Місяць тому +1

      Actually, if you look at the slide in my lecture in this timestamp (ua-cam.com/video/Bo0LNCr9BiU/v-deo.htmlsi=AVE5I__eOliULGZl&t=1877), you will see the pulsatile secretion of GH after GH secretagogues is gone by about 2.5 hours. So if one wanted a second large pulse of GH, they could dose it a second time.
      And clinically, with something like BPC-157 we have had some patients who respond better to dosing twice per day (as opposed to the same dose once per day), and we've even had patients who benefited from dosing Tb4 multiple times per day as they got an acute pain reduction following dosing.
      Peptides are cleared from the body extremely quickly, so in some instances multiple doses may be advantageous.