Is DNA the Future of Data Storage?

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  • Опубліковано 25 жов 2022
  • Could the future of data storage be DNA? It’s the original format after all, storing the information needed to build every living thing. and it has a handful of qualities that would make it perfect to store all the digital information in our world. With recent advances in DNA sequencing and DNA printing, it’s technically possible. But there are a few obstacles to overcome before this sci-fi sounding tech can become a household reality.
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    Credits:
    Executive Producer:
    Matthew Radcliff
    Producers:
    Elaine Seward
    Andrew Sobey
    Darren Weaver
    Host:
    Alex Dainis
    Scientific Consultants:
    Mark Bathe, PhD
    Karin Strauss, PhD
    Executive in Charge for PBS: Maribel Lopez
    Director of Programming for PBS: Gabrielle Ewing
    Assistant Director of Programming for PBS: John Campbell
    Reactions is a production of the American Chemical Society.
    © 2022 American Chemical Society. All rights reserved.
    Additional Sources:
    lewisdgavin.medium.com/google....
    www.genengnews.com/topics/omi...
    brighterworld.mcmaster.ca/art...
    phys.org/news/2017-03-short-m...
    www.twistbioscience.com/blog/...
    www.twistbioscience.com/blog/....
    accessmedicine.mhmedical.com/....
    www.nature.com/scitable/defin...
    www.twistbioscience.com/blog/....
    www.twistbioscience.com/blog/....
    www.genengnews.com/topics/omi...
    www.nature.com/articles/s4156...
    www.genengnews.com/topics/omi...
    www.genengnews.com/topics/omi...
    www.nature.com/articles/s4158...
    cen.acs.org/biological-chemis...
    dnastoragealliance.org/why/
  • Наука та технологія

КОМЕНТАРІ • 81

  • @enihil7713
    @enihil7713 Рік тому +7

    I love how you actually explain the subprocesses instead of just glossing over them and making us search elsewhere to find out!

  • @user-bp8yg3ko1r
    @user-bp8yg3ko1r Рік тому +25

    This was super interesting, enjoyed watching this a lot!
    Extremely well presented, thank you, Alex!

  • @KrashFries
    @KrashFries 11 місяців тому +3

    Imagine if we compressed the entire internet into a tiny test tube somewhere and some hacker manages to break the system by printing a swimming pool’s worth of cat pictures.

  • @joephalarope6880
    @joephalarope6880 Рік тому +12

    This will be the pinnacle of humanity! Your videos always make me smile, thank you)👍

  • @xBris
    @xBris Рік тому +16

    The biggest hurdle is the synthesis. Sequencing is getting exponentially better over time, but the synthesis barely evolved over the last decades. Chemistry is - unfortunately - not the answer here and we need more biochemical methods.

  • @IanGrams
    @IanGrams Рік тому +9

    This was an excellent and timely overview as a coworker was just wondering about this topic and I had the perfect video to send them. Thanks Dr. Dainis and Reactions crew!

    • @ACSReactions
      @ACSReactions  Рік тому +5

      We love to hear this-thanks for watching!

  • @avi12
    @avi12 Рік тому +8

    I think there will be two competing storage solutions in the future: DNA and light storage

    • @jeffbrownstain
      @jeffbrownstain Рік тому

      I don't think it will even be a debate.
      One of those two is easier to implement and has current realworld and practical applications.
      The other one is the topic of this speculative video.

  • @hotshotgolfer3079
    @hotshotgolfer3079 5 місяців тому +1

    Well Done. I am doing some reading on this subject this weekend. Sincerely happy I watched this presentation.

  • @perryallen9058
    @perryallen9058 10 місяців тому +1

    These are incredible videos! I'm so glad I stumbled upon your channel

  • @universx9645
    @universx9645 Рік тому +3

    Insanely good video! It's sad it has so little views...

  • @larva5606
    @larva5606 5 місяців тому +1

    Thanks for sharing. Any links to places we can stay on top of any developments regarding this topic?

  • @HMAOO86
    @HMAOO86 Рік тому +4

    Also, coding DNA would be a medical revolution!

  • @smrutiranjanswain869
    @smrutiranjanswain869 Рік тому

    Excellent explanation. Thanks

  • @abrar190
    @abrar190 Рік тому +1

    Awesome 😎 and Good Sharing 💗🌹👌

  • @Haileyhamm77
    @Haileyhamm77 2 місяці тому +1

    I feel like she’s trying to explain how the internet works to me in 1875, and my eyes are starting to cross trying to keep up🤣

  • @vast634
    @vast634 Рік тому +2

    That indirectly highlights how game changing the invention of the printing press was.

    • @jeffbrownstain
      @jeffbrownstain Рік тому

      Who anywhere ever debates such a topic?
      There's pretty much three big inventions EVER: fire, wheel, printing press. Everything else besides the nuke has been a footnote.
      Tf is wrong with the quality of comments on this channel, you'd think a video talking about dna data storage wouldn't have a bunch of idiots as its only commenters.

    • @vast634
      @vast634 Рік тому +1

      @@jeffbrownstain The most impactful invention on civilization was actually the Haber-Bosch process to industrially produce ammonia. Thats the invention that allowed the population to grow by billons.

  • @anushreevirtualgaming226
    @anushreevirtualgaming226 Рік тому +1

    I have selected this topic for my seminar report and Presentaion is goinh yo happen tommorow, If i have a ppt on this toic I will be grateful for such amzaing content u provided for free......Thnaks u very much ........

  • @Ceelvain
    @Ceelvain Рік тому +6

    DNA data storage seems awesome. But have other molecular data storage been explored?
    Nature has proven suboptimal countless times. And we do not have exactly the same requirement for data storage as life does for doing its life things (survive, replicate, fight off opponents, and so on).
    Granted, with DNA, life already made some tools to deal with it, and we made quite some more in the past century. But maybe something simpler could be better? I dunno.

  • @miketyson8236
    @miketyson8236 Рік тому +1

    Very interesting, but could you explain how did you converted the file into 0s and 1s at the 6:00 minute?

    • @jonsnow7844
      @jonsnow7844 10 місяців тому

      Are you serious? Hexdump.

  • @dharanimurugan5887
    @dharanimurugan5887 9 місяців тому

    Good explanation need this in a pdf format can you please🙏 this will more useful to me

  • @MisterBones223
    @MisterBones223 8 місяців тому +1

    If I could store the library of babel in my house, I can die happily.

  • @DukeBG
    @DukeBG Рік тому

    I think informational science parts of this video could be done better, but the cute picture of the dog fixed everything

  • @XSpImmaLion
    @XSpImmaLion Рік тому +1

    "Only" 20Tb? xD Holy crap!
    And here I am feeling I'm way overboard with my measly 3.5Tb NAS.... well, ok, I don't have an UA-cam channel to run.
    Anyways, great explainer! I've heard of DNA storage before but never explained this deeply.
    As tech giants are still using tape based and magnetic storage for deep storage, with a few operations going towards chip based, there will be lots of money being put into new tech like that... but it needs to strike a right mix there, which isn't going to be easy.
    I think of DNA as a base framework of storage down to it's insanely low volume... we'll likely reach it first instead of any other alternative because of the entire structure already built around other applications for DNA. It might not even be the ideal way of storing computational data, but because we already have a need for reading and writing DNA anyways, we'll likely get there faster.
    There is one other weird thing to note about data storage and how it's moving towards DNA though... and that is, there doesn't seem to be an intermediary between what we have now, and it. Perhaps there is some research on something that I didn't hear about, but even considering stuff that didn't quite pan out, it's not exactly midway there.
    For instance, there's some holographic storage tech that was considered in the past, further advances in optical data storage like fluorescent discs and multi layer laser discs, further advances in magnetic and chip based storage... but those are all incremental, they wouldn't be a generational step. DNA storage on the other hand is a several fold leap that requires a whole ton of advances in biotech to reach a stage of good cold storage method... but there is nothing there for fast access.
    It's like, I don't even need tens of petabytes on a gram of storage lasting for thousands of year... a shoebox sized Petabyte storage lasting a lifetime would fulfill the needs of the vast majority of people - but there doesn't seem to be anything there for that yet, not even theoretical, not even in early research stages. Which is a bit weird considering how much of a need there is for it, datacenters and all.
    Not that I know of anyways, if anyone knows something in this line please share.

  • @victororozco7727
    @victororozco7727 Рік тому +1

    When my Play Station gets DNA for memory, it will still not be enough

  • @Ceelvain
    @Ceelvain Рік тому +1

    Honnestly, I used floppy disks until 2006 - 2007. USB sticks became mainstream shortly after that.

  • @MrMysticphantom
    @MrMysticphantom Рік тому +3

    DNA storage has one big limitation. It only has 1 usecase, and that is data archiving. It is physically impossible to have that system deal with fast enough reads that happen several times a day, let alone minutes or seconds. DNA will degrade very fast per read if you think about it. So for an application/program it would be a very bad idea. However, long term storage data that gets accessed maybe once in years, and loading the data in speeds isnt as high a priority, its an excellent idea

    • @manticore4952
      @manticore4952 Рік тому

      We said the same thing about pretty much every single storage medium at one stage.

    • @FlatEarthKiller
      @FlatEarthKiller Рік тому +3

      DNA could theoretically duplicate and use the duplicate for reading while keeping the original dna intact.

    • @Gsus__17
      @Gsus__17 Рік тому +1

      those problems can be solved , it would only take DNA duplication technologies and rapid DNA readers

    • @grantmisinzo
      @grantmisinzo 7 місяців тому +2

      Modern DNA sequencing technologies, such as those based on next-generation sequencing (NGS) and nanopore sequencing, have significantly improved sequencing speeds over the years. These technologies can read DNA sequences at rates ranging from hundreds of megabases per second to gigabases per second.

  • @Sgt-Gravy
    @Sgt-Gravy Рік тому +2

    Sounds good in theory but low hopes for it working in practice.

  • @wanderingfido
    @wanderingfido 2 місяці тому +1

    I think this is a problem for AI to figure out. I'm too old and chronically ill. I need Tylenol. Unless somebody can resequence my DNA so I can once again bust a move, I'll be downstairs feeding me face. In the hopes it helps my three-day-long migraine. BYE.

  • @stephanieclaro9246
    @stephanieclaro9246 Рік тому +4

    (G)reat (C)hannel! (T)hat‘s (A)mazing! 🤯🧬

  • @SeekingTheLoveThatGodMeans7648

    Addressing and reading it would be a challenge, amirite?

  • @DanielDogeanu
    @DanielDogeanu Рік тому

    This is awesome, but needs to be a lot more orderly and reliable and resilient to be indeed used as storage. Plenty of time for scientists to solve these problems by 2030! 😁

  • @idobooks909
    @idobooks909 Місяць тому

    Yes! My new purpose in life.

  • @nikokapanen82
    @nikokapanen82 Рік тому

    Theoretical maximum is a zettabyte per gram. That is a billion terabytes, thousands of years of 4k videos

  • @GrantSR
    @GrantSR 10 місяців тому

    3:43 - Wait! Y'all might want to consult with your biology grad-student friends. Chickens ARE dinosaurs.

  • @Haileyhamm77
    @Haileyhamm77 2 місяці тому

    I can hardly grasp this concept if at all, but that sounds like a potential whole new area of a black market😆🤣

  • @ayoCC
    @ayoCC Рік тому

    Can DNA be constantly read and written over?

    • @davidhansson7041
      @davidhansson7041 11 місяців тому

      Think of it more like printing a paper then faxing or scanning it.
      You have to print the entire DNA “write” data to it. That will create a new strand of DNA. You could reuse the bases but it’s still today a complicated process.

  • @zyxvutsrqpo8537
    @zyxvutsrqpo8537 Рік тому

    Wow, just think of it - I am no longer a “resource “
    I’ve been promoted to a new “type of asset class”

  • @retromograph3893
    @retromograph3893 Рік тому

    You only need one usb cable of each type

  • @paullatham9832
    @paullatham9832 3 місяці тому +1

    People who say they can remember past lives just might be right then :O

  • @nickytaylor7532
    @nickytaylor7532 Рік тому

    what if it hurts?🤔 I wouldn't use it.

  • @infinityzer054
    @infinityzer054 Рік тому

    Viruses(literal), diseases, bacteria:”imma eat it”

  • @Bludgeoned2DEATH2
    @Bludgeoned2DEATH2 Рік тому +3

    “Floppy disks”
    I think my back just broke hearing that lmao

    • @jeffbrownstain
      @jeffbrownstain Рік тому

      I'm 25. My pc still has a floppy drive, one I installed myself.
      Stop acting like you're a revolutionary.
      You're just an oldhead who can't adapt, you aren't special because you know what a floppy disk is.

  • @pedrosmith221
    @pedrosmith221 Рік тому

    And then it would take 9 months to download a movie from the cloud 😅😅

  • @ireallyreallyhategoogle
    @ireallyreallyhategoogle Рік тому

    By 2030 no one will need to store that much data, everyone will just want food and shelter from the ecological disaster that will be our planet.

  • @devluz
    @devluz Рік тому

    7:19 I was suspicious of these claims but the movie is just 50 seconds. Kinda cheating ;)

  • @selvammatthys
    @selvammatthys Рік тому +1

    Why would we ever do that? DNA is so sensitive to acid, base and radiation. It is the replication that makes it resilient, the medium itself is weak. Why not storing information on Atomic memory instead? You have way more knowledge than I ever could have but I think this is wishful thinking on your part to think we could have this outside a research lab in 10 years. (Love your channel.)

    • @lukas4235
      @lukas4235 Рік тому

      DNA is very stable. Why would it come into contact with acid, base or radioation and why would that be more of a problem than with current systems? It allows for very long data storage that outperforms MOS-FETs in longevity and size.

    • @Ceelvain
      @Ceelvain Рік тому

      @@lukas4235 radiations are everywhere, all the time.

    • @lukas4235
      @lukas4235 Рік тому

      @@Ceelvain Radiation levels are too insignificant

  • @jeffbrownstain
    @jeffbrownstain Рік тому

    Didn't humans figure how to literally store patterns of light inside of crystaline structures?
    Seems a lot more robust a computing medium than biological and degradable genetic material.

  • @IJGR98
    @IJGR98 Рік тому +1

  • @GrimLocke161
    @GrimLocke161 Рік тому +6

    I was hoping your next video would explore the rampant carcinogenics of glyphosate. You should really consider making amends for supporting Monsanto.

    • @xBris
      @xBris Рік тому +1

      Do you have a source for that? Because it sounds like nonsense.

    • @GrimLocke161
      @GrimLocke161 Рік тому +3

      Bayer payed $10 billion to nearly a hundred thousand claimants to settle their class action suit that glyphosate caused their non-Hodgkins Lymphoma. You should also look within as to why that would be so impossible to you and commit to making drastic changes to your mindset.

    • @Bludgeoned2DEATH2
      @Bludgeoned2DEATH2 Рік тому

      What’s your solution? Going the way of Sri Lanka?

    • @GrimLocke161
      @GrimLocke161 Рік тому +3

      @@Bludgeoned2DEATH2 understood. I’ll block you, now.

    • @ImTHECarlos98
      @ImTHECarlos98 Рік тому +1

      @@GrimLocke161 I don’t disagree with you necessarily, but don’t be such a pansy when taking criticism. 😂

  • @dragonskunkstudio7582
    @dragonskunkstudio7582 Рік тому +2

    It's too temperature sensitive. One temperature mishap and all your DNA breakdown into to pablum. So that has to be more robust.

  • @JWentu
    @JWentu 7 місяців тому

    0:45 wait wait wait you can't make such claims without some more details. What do you mean with "every book"? You mean "every book" once or all the copies of that book? How many Harry Potter books? seven or... billions of copies of those 7 (or whatever, sry HP fans) books?