GLP-1 Weight Loss: Is It Worth The Cost & Side Effects?

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  • Опубліковано 23 лис 2024

КОМЕНТАРІ • 84

  • @annahoover5296
    @annahoover5296 28 днів тому +8

    This medication has changed my life,I a. A diabetic have been on mounjaro for 17 months,I am at the highest dose 15,started weight 240lbs today I weigh .141.feel great A1C 4:9.all other blood work great.❤

  • @MindyMikami
    @MindyMikami 28 днів тому +11

    Hi guys! My side effects could be 10 times more than they have been and I’d still take my Mounjaro! SO worth it after losing 77 lbs. My food noise disappeared almost immediately, but I’ve not had to struggle to eat… maybe because 30 weeks in I’m still on MJ 5.0. 🤷‍♀️ I mostly experience constipation, but that’s something I had before GLP-1 and is totally manageable. Oh, and my mom might not know I’m taking MJ, but my husband, my son, my triathlon coaches, and a few trusted coworkers know. I also wear a Road I.D. Bracelet that has a link to my medical history in case I’m ever in the ER and unable to respond. 💪🏻 😉 Great video!

    • @thedownsized
      @thedownsized  28 днів тому +1

      Hey Mindy! Wow I didn't realize you have stayed on 5mg for your 77# loss! That's great! Good idea with the Road ID bracelet and sharing your info with a few trusted people.

  • @marieque9298
    @marieque9298 28 днів тому +5

    I really enjoy these daily videos watch while I use my treadmill

  • @MarleneLiraMarrero
    @MarleneLiraMarrero 28 днів тому +6

    It’s worth every single penny

  • @chap3rwe
    @chap3rwe 28 днів тому +2

    Great segment. I’m in week 3 of taking Zep, and have experienced mild side effects: nausea, fatigue on days 1-2, post-injection. Last week was sick after a birthday dinner, but bounced back quickly. I’m expecting to go up at next round of Rx… curious to see how my body responds. Biggest advantages: no food noise and the remarkable lack of concern about losing weight - agree that this is an incredible feature of these meds.
    Nice work, you two - look forward to your vlogs!

  • @tammyrunyon4457
    @tammyrunyon4457 28 днів тому +5

    The medication (Zepbound) definitely has changed my taste buds. I’m use to be a margarita drinker myself. I usually get the big fish bowl margarita they’re called here at some places every Friday at our favorite Mexican restaurant that has come to a halt. Now I drink lemon water. Occasionally, I’ll have a small skinny margarita. I’ll trade drinking for weight loss any day, down 40 pounds in almost six months. Haven’t felt this good in years. Pushing maximum density in my jeans was so uncomfortable.

    • @megspositiveoutlook5772
      @megspositiveoutlook5772 28 днів тому +1

      @@tammyrunyon4457 I’m experiencing the same thing with coffee! Even though I haven’t been an everyday habitual coffee drinker in a long time, I would still enjoy a large latte every now and then. Now it’s like I can only drink maybe 1/4th before I lose interest and don’t want to finish it.

    • @thedownsized
      @thedownsized  28 днів тому

      My favorite joke: How many of these Skinny Magaritas do I have to drink before I see results? :)

  • @Jo-AnnFrey
    @Jo-AnnFrey 28 днів тому +1

    The side effects are manageable for me. I had some fatigue for the first few months, but it took a bit for me to realize it was from the shot. I initially thought it was from poor sleep. I take my shot usually on Thursday so the fatigue might hit on Sunday. Rarely, I took a nap. And I get constipated, which I watch carefully and treat with miralax, Mag07, fiber gummies, prunes and water. I have been doing this six months and have been losing less than a pound a week on average. Despite this, i am thrilled and will use this medication as long as I can. At the rate I am losing I figure I have at least another 6 months to go, maybe longer. I have been using both branded Zepbound and trizepatide. I would not let the potential side effects deter you from taking this medication. My doctor supports using GLPs, but is not a fan of the compounded meds. I find the compound meds to be easy to administer and I can control the dosing. I also think it is nearly painless and I prefer it to the pen. Will use what I can for as long as I can.

  • @Motowndonna8
    @Motowndonna8 27 днів тому +1

    I am so glad I watched this video. I’m 40 weeks into Zepbound for 3 months and compound for the remainder. Down 55 pounds. Generally I say I’ve had mild side effects. I just increased to 12.5mg and I have those terrible burps and heartburn. Darn! I thought that wasn’t going to happen to me…OTC PPI helps. But…I totally forgot that for several months I was so exhausted all the time but now I’m not. 😅 I have been very dehydrated the entire time and do a lot better now with 60-80 ounces of electrolyte water daily. But I do take HBP medication with a diuretic. I have lost just about any cravings for coffee 😢, diet soda and alcohol. And I must take lots of fiber supplements every day. The over excessive fullness has diminished overtime, which isn’t a good thing. I recently lost my sister to cancer and I allowed myself comfort eating and sweets but oddly gained only a pound.

    • @thedownsized
      @thedownsized  27 днів тому

      I’m sorry about your sister ❤️

  • @Susansnewera
    @Susansnewera 28 днів тому +1

    Zepbound almost 5 months. 7.5 mg zepbound. Weight loss 26 pounds. History severe constipation. On zepbound less severe. Nausea decreased but decrease oral intake food still strong 3 rounds 7.5 mg. Within 8 pounds of goal. Long trip to goal started 8/2021 gastric bypass. Leveled out after 2 years with no gain or loss with change in diet. Zepbound and stability of small stomach was key to my 40 years of over weight obesity. Just wish it was available sooner. But very happy now age 60

  • @jayhoughton4174
    @jayhoughton4174 20 днів тому

    What a lovely couple, great listening to you guys 💙

  • @christinagipperich2780
    @christinagipperich2780 28 днів тому +1

    The reduction of “food noise” is a huge win for me. I would tolerate the stomach issues just to stay rid of food noise. Food noise has plagued me my whole life so to be free of it is a life altering. To say it changes how you think is not an exaggeration.
    Speaking of traveling…has anyone ever had issues at an airport with taking syringes in their carry-on (even with the prescription with it)? I would hope not but I wouldn’t want to find out the hard way.

    • @thedownsized
      @thedownsized  28 днів тому +1

      Thanks for commenting /we have flown with our meds, and carried them through tsa with no issue - we have a couple videos on it if you are interested

  • @marimerf6685
    @marimerf6685 28 днів тому +3

    Hi ! Love your channel ! I tirzepatide No side effect at all! 🙏! 💯% worth using it!
    I felt noise reduction and i feel A lot more Relax ! Less my anxiety ! I use magnesium gel cap before using it ! So i only experience wonderfull Feelengs ❤❤❤

    • @dayanahmaahzhnahyasharahla7606
      @dayanahmaahzhnahyasharahla7606 28 днів тому

      @marimerf6685 yes same for me! No side effects whatsoever. I'm 6 weeks in on Zepbound and starting my 3rd week on 5mg. I feel great and the inflammation in my body has really decreased! This medication is truly amazing..

  • @mmsfoxxie1
    @mmsfoxxie1 28 днів тому +3

    I still think a lot about food but it’s different in that now I think about making myself eat regularly. Unfortunately, nothing tastes really good anymore. My favorite pumpkin spice latte k cup coffee is almost undrinkable. Glad I don’t like Diet Coke anymore so that’s a good think. Glad I still like my Fairlife Core Protein drink because I’ve got cases of it.

  • @Steph_in_the_Garden
    @Steph_in_the_Garden 28 днів тому +1

    Thanks for the great video. I have very few side effect as well. Constipation is the one I have had to actively managed. The magical trifecta seems to be for me metamucil (the sugar free drink), a stool softener and a magnesium supplement (250 mg magnesium glycinate). On occasion Mag O7. But this seems to work for me, and hopefully helpful for others. Tried the fiber gummies and they didn't work for me.

  • @DebbieS564
    @DebbieS564 28 днів тому

    The side effects are manageable and the weight loss/health benefits are so worth the nausea, constipation, etc.

  • @Deanriley
    @Deanriley 28 днів тому +1

    I’ve had very few side effects; mostly just bloating which was easy to deal with.

  • @barbhuber7502
    @barbhuber7502 28 днів тому +1

    I have had to change the way I plan meals and reduce the sizes of meals. I’ve never been nauseous enough to take medication for it and never vomited but nausea is low level present sometimes. I try to plan very plain meals. A small amount of a starch, a green vegetable and a protein of some kind. I definitely am experiencing fatigue. I use Fiber We’ll gummies and they help.

  • @johnnaledoux2554
    @johnnaledoux2554 28 днів тому +1

    Hello🎉 loving GLP1
    People had a lot of the same comments about cheating and losing too much when I had gastric bypass surgery.
    I am not listening 😂
    This 💯 worth it❤❤❤

  • @lindaanderson788
    @lindaanderson788 28 днів тому +1

    Hi from Northeast Ohio!! This is an excellent ID for a talk. So many people won’t start because they feel are concerned about size effects..

    • @thedownsized
      @thedownsized  28 днів тому

      Thanks

    • @jc10907Sealy
      @jc10907Sealy 28 днів тому +2

      The ‘size’ effects are pretty great 👍

    • @MrTimcrowley
      @MrTimcrowley 28 днів тому +1

      Evening from a very autumny and mizzly London. I have become absorbed by your journey and the way you explain things to the layman. It has enabled me to go on my journey and has helped me to explain GLPs to some overweight friends three of whom have now started their own journey. Thankyou

    • @thedownsized
      @thedownsized  28 днів тому

      Nice!!

    • @MindyMikami
      @MindyMikami 28 днів тому +1

      @@jc10907Sealy 🤣🤣🤣🤣

  • @Natalie.D
    @Natalie.D 28 днів тому

    Wegovy almost 2 years on it. Lost 70lbs, now in maintenance for the past 8 months. In the beginning I had some side effects, constipation, headaches, dehydration. But I could fix all those things by upping my water intake, adding electrolytes and working with a registered dietician to make sure I was getting enough food and the right balance for me.

  • @DrPayneNestor
    @DrPayneNestor 28 днів тому +1

    Jo Jo is the sound engineer- not just a cute cat 🐈 😂

  • @joycemcclellan9263
    @joycemcclellan9263 28 днів тому +1

    I’m curious what yall do for work. Your business

    • @thedownsized
      @thedownsized  28 днів тому +1

      CD: we talk about it occasionally - we founded and run a trade association for the private brand industry. This is the industry that owns, manages, manufactures and markets brands owned by retailers: Great Value at Walmart, Husky at Home Depot, Kirkland Signature at Costco etc. so our members are retailers, manufacturers, agencies, software companies, etc who help retailers build their brands. We then produce content, conferences and networking for our members

  • @joelle6933
    @joelle6933 28 днів тому

    I find if I just push thru the fatigue with a walk or head to gym I can work thru it , as far as constipation I have alway struggled with it but a year into this I think I am actually a bit more regular.

  • @karenforsling4959
    @karenforsling4959 28 днів тому +1

    I’ve been using Zepbound since mid-June and recently went up to 7.5mg. I had no notable side effects on 2 and 5 milligrams, but on 7.5, I’m experiencing significant nausea and vomiting. For each of the last four weeks, nausea sets in 48-72 hours after the shot followed by a couple sessions of vomiting and sometimes diarrhea. This last week I thought I was in the clear, but 96 hours after the shot, nausea woke me up at 2am and then I had to RUN to the bathroom to 🤮. I don’t know if I should go back down to 5mg or keep pushing through on 7.5 and hope my body adjusts. Would love any tips or insights.

    • @tammyrunyon4457
      @tammyrunyon4457 28 днів тому +3

      Well, if you’re puking, I’d go back down if the lower dose was working

    • @marimerf6685
      @marimerf6685 28 днів тому +3

      If you were losing weight go back!

    • @thedownsized
      @thedownsized  28 днів тому +2

      Your body is definitely trying to tell you something! I would suggest to ask your Dr., but it does sound like you might try going back down in dose to 5 or even like 6mg. If it's been 4 weeks on on 7.5 and your still throwing up, I would move back down.

    • @karenforsling4959
      @karenforsling4959 28 днів тому +1

      @@thedownsized Thanks so much for your thoughts, much appreciated.

  • @mmsfoxxie1
    @mmsfoxxie1 28 днів тому +1

    I’m afraid I’ve joined the “stockpile”club, lol. I don’t trust that Mochi will be able to follow through on what they say about keeping tirzepatide available to us. I just started my journey in mid August so I need at least until June to reach goal.

  • @michaelclanton1152
    @michaelclanton1152 28 днів тому

    In a doctor live q,a said it takes 4 half lives of tirz to get out of your system totally and sema is 7day half life so 4 of those related to your stop for a few wks Laraine.

  • @annahoover5296
    @annahoover5296 28 днів тому

    Hello you two.

  • @Mymar5
    @Mymar5 28 днів тому

    What do you suggest for nausea?

    • @thedownsized
      @thedownsized  28 днів тому +1

      Talk to your doctor about zofran

  • @CrissyRogers-l3k
    @CrissyRogers-l3k 28 днів тому

    How do you deal with tiredness

    • @thedownsized
      @thedownsized  28 днів тому +1

      Laraine here- I used to nap at the beginning. Make sure you are drinking water and eating enough protein.

  • @elizabethbagwell3795
    @elizabethbagwell3795 28 днів тому

    I think about all the $ im saving not eating fastfood daily not drinking a bottle of wine a night not morning to bed daily. 🎉 Definitely worth the cost. Also a1c from diabetic levels to normal ❤ life saving medicine 💉

    • @thedownsized
      @thedownsized  28 днів тому +1

      My savings from not drinking wine almost pay for the medicine! :)

  • @genawilson3436
    @genawilson3436 28 днів тому +3

    I always get a terrible headache 3 days after I take my shot.

    • @tammyrunyon4457
      @tammyrunyon4457 28 днів тому +2

      Yes, I used to never get a headache, but I’ve gotten a few since being on this medication. If I eat or maybe have a cup of coffee it will go away.

  • @ragingrah3789
    @ragingrah3789 28 днів тому +1

    I’m jealous you need jackets outside. It was 95° where I am 🥵. Enjoyed the talk!

  • @Jack-gq7kn
    @Jack-gq7kn 28 днів тому

    I can adjust my dose. Do you think I should increase the dose if I’m still losing at the lower dose? It’s hard to get good advice from online doctors.

    • @megspositiveoutlook5772
      @megspositiveoutlook5772 28 днів тому +2

      I’ve heard from numerous people say they wish they didn’t rush upping their doses.
      You will, overtime, build up a tolerance. And there’s only so many doses available to increase to. I’ve heard over and over not to increase your dose until you experience multiple weeks of weight stall. Even then, I’ve heard suggestions to change up your injection site to see if that kickstarts your downward trend before jumping up in dose.

    • @dianes.1909
      @dianes.1909 28 днів тому +1

      Hindsight here. If loosing, no.

    • @thedownsized
      @thedownsized  28 днів тому

      Make sure to talk to your local physician. They can help you based on your specific health needs. And will have more information.
      In general we say move up slowly. And maintain a dose as long as you are losing weight, feeling satiety and your food noise is managed. Typically we will wait at least a few weeks when weightloss slows or stops as sometime your body just has a kind of it’s own.
      You might try adjusting your food, eating a healthy varied diet and making sure you are in a calorie deficit

  • @AnnHoffman-lm5fm
    @AnnHoffman-lm5fm 28 днів тому

    My company will not allow extra shipments of trizepitide say int wasn't staple after 45 days. How are you getting stockpiled trizepitide or is it only zepbound?

    • @thedownsized
      @thedownsized  28 днів тому

      Zepbound

    • @marimerf6685
      @marimerf6685 28 днів тому

      Which Pharmacy ?

    • @AnnHoffman-lm5fm
      @AnnHoffman-lm5fm 25 днів тому

      I use a compounding pharmacy in Utah.

    • @thedownsized
      @thedownsized  25 днів тому

      @@AnnHoffman-lm5fm Aequita?

    • @marimerf6685
      @marimerf6685 25 днів тому

      @@AnnHoffman-lm5fm I use Hallandale pharmacy Fourt Lauderdale it last 1 year and you can order 3 or 4 month with a Dr. prescription!!

  • @rebeccashockley189
    @rebeccashockley189 27 днів тому

    You both seem to be very comfortably off. Unfortunately a lot of AMERICA is struggling in this economy and cannot afford this medication. It’s a shame !

    • @thedownsized
      @thedownsized  27 днів тому

      CD: Yes we are lucky. One of the reasons we fight for affordable access is we know that it can change everything. Its very expensive both economical and physically to be poor. We must change!

  • @marimerf6685
    @marimerf6685 28 днів тому +2

    Semaglutide awfull lots of side effect for me stomach pain ! nauses ! NO weight Loss

  • @1tennismama
    @1tennismama 27 днів тому

    Foods taste differently

  • @michaelclanton1152
    @michaelclanton1152 28 днів тому +1

    Laraine being hungry on the plane was a good test for you on the upcoming medication stop.