Could a blind eye regenerate? - David Davila

[@foxygal7530]

My best friend has Retinitis Pigmentosa. He is only 14 but will be totally blind in 2 years. He loves this video and from what he could see with 25% of his vision, he loved it! He said thank you to all the people who helped make this video and are continuing research! He hopes to see them some day.

[@lindadaniel2345]

Foxy Gal he will

[@heidihinter4961]

Show your friend this video!!
ua-cam.com/video/0acB1yfankQ/v-deo.html
They are on the path to fix this!

[@clarkevander]

This comment is a year old 😭😭😭

[@futuristiccat5636]

Foxy Gal wow, this is two years later... so he’s completely blind now??🥺😔

[@wio5021]

Foxy Gal give us some update 😓😢

[@RikkTheGaijin]

Now can someone explain to me how the hell did somebody found out that the zebra fish can regenerate it's eye sight?

[@Tinky1rs]

They have been known to regenerate many parts of themselves, so I guess some interested folks blinded them and checked their eyesight over time.

[@TheFerretofEarth]

Errno That's called torture

[@AethernaLuxen]

Marine biologists, they're job is to observe manipulate and do random stuff with fish

[@gabrieleamore3081969]

This is what is called basic research. You study things in other living beings just because it's interesting, knowing that one day what you find out will be of some use

[@fullmetal1161]

Aquaman told them.

[@taylor1038]

I had a macula off retinal detachment in my right eye. I noticed a shadow slowly encroaching towards my center of vision. I sought medical attention but thanks to good old American Heath care (or lack there of) it was too late to save the fine detail vision of my macula. After a corrective pars plana vitrectomy my vision was mostly restored, just one more surgery to go.

[@oneness_gaming]

Sorry to hear that, good luck to you buddy!

[@taylor1038]

Bob Bobby Thanks man! I'm still optimistic about things. Just taking every day as it comes.

[@TheCrayonMan529]

+taylor1038 Hey! I have had a retinal detachment cause of sports, but I didn't do anything about it for two years. The upper part of my vision is gone. What is corrective pars plana vitrectomy? What do they do? I actually have a cataract surgery coming up soon cause of the gas and oil bubble they put into my eye. I have had 4 eye surgeries in the past year. It would be great to get that part of my vision back.

[@taylor1038]

TheCrayonMan529 It sounds like you have had at least one pars plana vitrectomy. I'm sorry to hear about your situation. :( It has been about a year since my surgery and my vision hasn't improved much in that eye.

[@heyman6412]

taylor1038 it has been 2 years since you commented, are you OK now?

[@petergrimstad6519]

These guys make it seem so easy.

[@ButtKraken01]

That zebra fish is too cute

[@JustTheHighlights]

I wanna eat it so I can gain it's powers. That's how it works right?

[@ButtKraken01]

yes

[@jesselox3470]

Ive had zebrafish in aquariums before, one of my first lost one of its eyes before i got him and still managed to be the cutest thing and then one of my last managed to survive MONTHS in a tank that wasn’t being taken care of. No filter not heater no water changes, zebrafish are hardy and very unique fish that need more recognition AND have helped us a lot in research also they’re as cute as those animations!

[@marlonhernandez2467]

All these eye vids have restored faith in my eyes/vision.. thanks from the bottom of my heart

[@TheGamingMotionTGM]

Whoever succeeds in the methods of restoring eye vision like the zebra fish may have their faces shown on Time magazine

[@reneastle8447]

@@TheGamingMotionTGM We can make that happen. All we have to do is create campaigns, raise funds, and use medical innovations to make this dream a vivid reality.

[@SuperAtheist]

@3:33 is that a flux capacitor?

[@NewZeroGames]

I really liked the animations in this video :)

[@brithefree8123]

NewZero same

[@blessc419]

Wikihow

[@karimmohamady7662]

@@brithefree8123 ok tankiyo

[@yan_man23]

Is it just me or does this guys voice sounds a bit robotic? Also great video. Hopefully we will be able to cure blindness.

[@ZuluAlphaParamedic]

Ikr

[@Tweogan]

Could we cure color blindness too? Can there be a way to trigger the growth of specific cones?

[@throwawayemail8450]

this

[@reneastle8447]

Yes we could, anything is possible. Clinical research is the key to finding cures.

[@couldyoubetender3480]

This made my eyes hurt

[@Lucuskane]

I think the Muller cells are activated by transcription factors-like signals from retina, these signals go on to induce specialization in areas of muller cell (gradient based). These specialized cells then replace the cells or truncated cells, which is what we see as regeneration. I think.

[@tyrmyrmidon2846]

It would be nice to revive my eyes, when I was young I didn't have glasses :(

[@rabiakasim1474]

same

[@AxiomofDiscord]

This is not a cure for glasses that is a lenses/focus problem. This is to regenerate or replace dead parts of the eye.

[@reneastle8447]

@@AxiomofDiscord It's possible, and we can make it happen if we stick together, brainstorm, and raise funds for regeneration of the eyes to happen.

[@loganhadam6118]

God damn zebra fish.
stealin' OUR superpowers

[@courtney.22]

"Which is why babies have such big eyes and why they're so cute" That last part tho 😂

[@electricenergy116]

courtney courteau I know right!

[@alexwang982]

Courtney Courteau theyre not cute!

[@hasnain9654]

Pi for you they maybe not cute 🙄🙄🙄🙄🙄🙄

[@Elizabeth-mj5br]

3:40 i love how the cone receptor is wearing 3d glasses😂😂

[@juanperezmaturana3675]

Good, but more important would be to focus in the repair
of the optic nerve, when this is damaged, causing blindness.

[@reneastle8447]

Of course, innovation can mean new medical methods to cure blindness, blurry visions, and glaucomas.

[@PRASANTHVP]

wow

[@SpiritBear12]

What about Macular Degeneration? That's what took my grandfather's sight. :-(
We all watched his slowly go blind over a course if 17 years. It started when he was 64 and ruined his retirement. He also had glaucoma and other eye problems that i don't remember the names to.

[@AxiomofDiscord]

I have lost most of my vision in one eye and it might be starting into the other from Glaucoma and I am currently only 39. Regeneration should help Macular Degeneration and it is further along than Glaucoma for treatments. Currently one Treatment is in Phase 2 clinical trials. Glaucoma is still at the pre clinical trial stage. But in 15 years I think both will have treatments to bring back at least partial site. My eyes are starting to stabilize so I might have functional sight until that day.

[@julesoxana3630]

Hope ur grandafther is doing well❤

[@martinmcr83]

Zebrafish is awesome, great video. The adult newt can also regenerate the retina, lens, limbs, heart, jaw, spinal cord, and brain. I hope in the future TED-Ed can present a video on newts regenerative abilities, it would definitely supplement this area of regenerative biology.

[@subashkannan5810]

Will this idea works in the regeneration of near by optic nerves...so that it aids in curing optic nerve hypoplasia?

[@nayakvaibhav7474]

Please Answer.
My friend had cancer called Ratinablastoma in the year 2006. Now he can see only with one eye ,the other eye was removed at that time.His optical nerve was damaged.My question is can he be able to see with both his eyes in the future ??
Please answer !

[@reneastle8447]

It can happen if we come together and create campaigns to have eye restoration without surgery become a vivd reality.

[@asomeami1305]

And 3:34

[@MrV1T]

Very nice and informative video. And should say - very great animation. Unlike in some latest video - very clean and clear, really helping to understand material. Good work!

[@noahfrench7412]

Wait so... are there Flux Capacitors in my eyes?

[@TravisMohan]

who knew zebra fish were so interesting, i remember having them in an aquarium

[@gabbonoo]

saffron helps fight (almost cures) macular degeneration if taken early and/or beforehand. How does that work?

[@Bronze_Age_Sea_Person]

Can other parts of the eye be transplanted after death like our retinas?Or just the cornea?
I've met a person that was blind before because of cornea damage,and before he told me that,I did a dark joke about eyes,blindness or corneas(I don't remember the joke anymore,it was one of those that depend of the context of the conversation I was having in that time) to him that creeply enough,he confirmed that was what exactly happened to him.He had a corneal transplant and started to see once again,since then,I wondered if it's possible to transplant other eye parts,not only with cornea.

[@asomeami1305]

Go to 0:35

[@MrIonB]

I want to kiss a zebra fish...

[@bryanp6354]

Could this potentially fix eyes on a person who experiences Colour Vision Deficiency?

[@nosoftspot9915]

Do you think it's possible for iris to regenerate, from someone suffering from iris atrophy?

[@unrefusableoffer4412]

Zebra fish is like Deadpool.

[@rimasdiaa7181]

my grandmother has been disorganized with 'diabetic retina
as many know diabetes often affects the rest of the body, including the liver and eye. every once in a while she gets surgery to ensure she doesn't eventually go blind. yet her eyesight is still worsening she can't even read without huge glasses

[@zerocalvin]

but does this mean, installing a robo eye capable of x-ray vision is no longer an option when this research is completed? because i think robo eye are cooler.

[@johnildineorquejo8285]

Beautiful. This is why I love TedEd. Very informative.

[@shadowdanielyt4730]

I request you to make a lesson about mystery or genetics of eye color.

[@LucasAlmanza]

1:35

[@ninja1676]

Being blind is probably the worst sense you can lose.

[@123_abct]

Thanks ted

[@BjarkeDuDe]

My dad has retinitis pigmentosa so this is pretty cool :)

[@nangomoore]

I have it too, its just not developed fully. What's it like? How far gone is his vision? Does he have night blindness too?

[@BjarkeDuDe]

He was very lucky that it never got to bad. He is nearing his sixties and it isn't getting worse. He needs a strong magnifier to read anything and to watch TV he has to sit right in front of it. When it first developed he was quick to adapt to it so he lives a pretty normal life, with a good job :)

[@nangomoore]

oh thats good! I hope mine doesn't get too bad

[@Romanattor]

@@nangomoore is your eyes going well?

[@FrozenAmy]

I got a bit confused, does the human eye have those "Muller glia" sells?
is it the sells themselves or it's their regenerating function that is so special about the zebra fish?

[@shellysingh1625]

the zebrafish was so cute

[@alexsh4517]

The clue for this is water! Blind people should open their eyes in the water

[@asomeami1305]

There were so many back to the future references

[@mightytaco123]

3:40
Dude was that the flux capacitor?

[@greatsquarebee]

I dont know who is looking for the smirk but here it is 0:53

[@TheIsaacShin]

We learn so much from nature!

[@westerp]

Although we share a common ancestor with the zebra fish it's likely that they did not have that trait even though most of the eye probably was very similar. The trait would have been much more widespread with a lot more species having it. I wonder why zebrafish has this. Their ancestors must have had a harsh time surviving such that this trait was vital for their survival at one time.

[@jyothiraj5857]

I strongly believe that someone will comeup with a great discovery that some natural plants or exercise or else could longer the life or rods/cones cells and thus blindness can be cured 😀
I have already heard of brain lesions are not permanent and they get resolved under proper condition
Similarily about neurogenesis
Some day My belief would come true

[@KavitaSingh-zi3sc]

My son is suffering from total retinal detachment and he is just only one year and doctor said that there is no treatment of this disease pls guide me about this is. There is any treatment of this

[@rubyJJHML]

EYE SEE what you mean it REFLECTS my past

[@arthurbenjamimguimaraes7372]

Loving zebra-fish

[@cathysosa4508]

My name is Cathy and that is happening to me I already can't see out of one now my left eye is cloudy what can I do before I lose my eye sight please help

[@-vodo-8572]

I never want to go blind it is my wish to never go blind

[@goxr3plus_studio]

Most people see sharp but they are blind because of their brain.
This video is fantastic!!

[@n0nenone]

This is an insane insult dude 😢 ouch

[@zakariaabdimohamed7063]

My father is blind totally, i wish he could receive this kind of treatment but i don't think he will ever get it because he's in his late 80s and in a third world country ☹️

[@reneastle8447]

I am sorry for what happened to your father, Zaharia, but there is still hope for other to have this innovative treatment.

[@limerence8365]

What will always be true is that if you put just a little too much detail into drawing eyes, they can become really creepy!

[@Lugaid13]

Love your constant BTTF references!

[@subashkannan5810]

Really u guys..are making a really good info in a awesome way...👏👏

[@captainpalegg2860]

Great Scott!

[@themotherbrassica]

There's also the ethical and moral conundrum, though. Not everyone without sight thinks of him or herself as "broken" and in need of a "fix," so who are we to not even consider that?

[@diamantbelallari669]

Really great and informative video!Science is always so interesting.Life is so much better with science,especially medicine :)

[@dald22]

me in 2015: hay future me dose this happen in 2019
me in 2019: no but we have egg dog
me in 2015: oh *THAT'S WAY BETTER*

[@masood-msd2570]

Luv the animation

[@Serialasked]

I can see why this is an interesting topic

[@arshadimam5010]

sir I am to surfing from retinanitis pigmenttosa . now I can't see in both side in daylight , now what to do

[@ASLTheatre]

So we don't need to harvest from different places Stem Cells? We can just grow them from these fish?

[@Kalokkkyo]

Do humans' eyes have the Muller Glia structure?

[@xtrmjedileal]

Great vid guys

[@36.phamminhtuan17]

Replenish

[@SundusYousuf]

Listen to this podcast, there are some interesting facts about vision. There is a specific part (40:00) that relates to how images are constructed in our brain, even for bind people.
www.thisamericanlife.org/radio-archives/episode/544/batman

[@NicoleTorres217]

But it could make a big problom

[@Hommer94]

Was that the 'Back to the Future' time traveling device. that 'Y' shape thing

[@MrBrineplays_]

If your parts of the eye has an eye too
They maybe blind too
And maybe thier part of the eyes has another eye
Eye
Eye
So many eyes

[@Electroblade360]

THIS IS MAGIC!!!!!

[@kritikumari8104]

Me : hey zebra fish! Can u donate your eye to me?
Zebra fish : hmm. Take, I will regenerate one :)

[@AA-zu3pw]

The Zebrafish = wolverine lol

[@Saurabh_Tewari007]

We can't even make our crystalline lens change shape, it would take really long to regenerate retina

[@sktomicron7532]

good morning

[@Alanzice]

The Retina, Woohoo!

[@ErikOrjehag]

The flux capasator!!!

[@Kelly191014]

can a zebra fish be immortal?
they can even regenerate the heart so they won't die?

[@justsomeawesomedude2608]

Kelly
No creature of the world is immortal! This fish can still die of old age, blood loss (if a predator eats it in half or something), disease, get eating, and (the most obvious one) take the fish out of the water and so on...

[@JohnMark-bx1ks]

that fish uses special medative techniques to regrow complex celsl.. only intuition can comprehend the dephtness ...

[@reinatr4848]

So intuition is over science?

[@itsmeroky]

Zebra fish is marine Deadpool.

[@victoriaminns6436]

I need help for a great person

[@divyanarasimhan460]

I don't understand😦...can anyone say could a blind eye can regenerate?...can able to see?

[@victoriaminns6436]

Plz help

[@ryanwelsch2402]

Your eye can fix itself, but only if you let it. The reason most think the eye can not heal, is because most people have clogged up their Lymphatic system and do not know how to unclog it. If the body cannot remove cellular waste, it has trouble healing.

[@reinatr4848]

Ah yes, big words to push woo.
This is one of the top sites I found about it:
synergyhealthassociates.com/blog/cleanse-clogged-lymphatic-system/
It's a chiropractor.
And it sounds like an alternative medicine cure-all
Its predictable
-eat good food
-breathe deeply
-meditate
-F&%$ BIG PHARMAAAAA

[@H0lly]

Cool video😃

[@user-wy4rx6fp8u]

That zebrafish is cute~

[@UHFStation1]

I worry we won't be able to regenerate eyesight until well after Star Trek TNG with Geordi.

[@Zachreactsto]

Hmmm I lerned something today

[@UsDiYoNa]

This has been done successfully now, right? Or am I misremembering what I read?

[@nathanielburgess5311]

I can go blind and unblind

[@kayk1931]

......? Please explain how?? Blinking?

[@crose4247]

Wait so the mice can also regenerate the eye like the zebra fish?

[@Doomroar]

Why would we lost such an useful quality? which stupid ancestor of us decided to go and reproduce without having that awesome power of retina regeneration!?

[@woodfur00]

We're not descended directly from zebra fish. Our stupid ancestors never had that ability.

[@Doomroar]

If they never had it, how can they consider that we lost that ability then?

[@woodfur00]

RoarOfDamnation Well, there's a difference between actively having the ability to regenerate photoreceptors and just having the potential for modification. When they said that, they were referring to the latter, and I see no reason we shouldn't have that potential, if mice do. (This follows the assumption that white mice are terrestrial creatures, rather than hyperintelligent higher-dimensional beings.)

[@Doomroar]

You must be the wisest mine-turtle ever.

[@truvelocity]

woodfur00 All mice can't do that either, they simply manipulated a gene from the zebra fish into the mouse.

[@XiethOfficial]

Hey, step cell.... W..what ar.. are you doing step c..cell?!!!

[@AtheistEve]

Babel fish for ears; zebra fish for eyes.