Sir I've never - in nearly 30 years of practice in the direct realm of pain- seen a more succinct yet understandable explanation of the ascending pathway .... and in 12 minutes !!! You Sir have a gift
At first sight the study of human anatomy may appear very difficult. It is tru?e that it is not simple and your studies wont change that. As for being overwhelming, this can be solved if you take it one step at a time. I found an article on Sebs Study Crammer very useful for this.
I liked the way you gave an overall introduction to pathophysiology of pain, and what I truly liked is that you draw structures that can enhance our understanding and give us an insight about where exactly does pain processes happen through numerous pathways
Never realized I was a visual learner till I got to this video. Explained what I've been reading in my book for 4 hours now and not fully comprehending until watching this...Keep doing what you're doing, Sir. You're the real MVP!!!
I appreciate this video as the *survivor of a spinal injury* (L1 compound fracture) resulting in 2 pain disorders (central + CNS pain syndromes) & a related sleep disorder (narcolepsy). I've lived with relentless pain for 14 years, since I was a teenager, & have no hope of achieving any meaningful relief, but I still want to understand as much as I can.
Wow. I have been looking at diagrams and reading my lecturer's notes for days now and wondering if I'll ever understand it. Thought I'd check youtube for "how to pass pathophysiology" haha and found this instead. In 12 minutes you have become the saviour of my sanity. You are amazing, thank you!
I love your videos! I tutor at a junior college, and I use your videos to illustrate what I am trying to explain to my clients. Thank you! Keep making more!
Really admiring your efforts to make us learn easily,,, Small correction:- NOCICEPTORS ARE OF 3 TYPES THOSE ARE 1)A-BETA IN SKIN 2) A-DELTA AND C FIBERS IN SOME PARTS OF SKIN,MUSCLES, VISCERAL TISSUES,
ONE mistake, the spinothalamic pathway for pain travels up the LATERAL branch, not the anterior as shown (touch and pressure are anterior, pain and temp. are lateral), however AMAZING work and I'm learning faster than ever with your work :) a big thanks.
***** Correct me if I am wrong, but doesn't the anterior spinothalamic tract carry pain fibres for everything other than information from the limbs? If I am correct, then this would indeed mean that the information in this tutorial is actually correct!?
I accept what you have written - definately not as easy than some people make out to treat neuropathy at home. Be cautious and take advice from other people. I searched round many websites and found some expert advice by searching google on sites like Gabs Neuro Guide. Good luck and hope you succeed!
That would take 30 seconds: Pressure and fine touch sensors share the same tract as pain travelling through the spinothalamic tract (either anterior: fast localized or lateral: slow unsure throbbing). Since they converge on the same Dorsal horn on the spine, if you rub a hurt area after scraping your knee, the fine touch Limenscal Tract fires like crazy effectively "taking over" the pathway with more touch going in the dorsal horn than pain. Think of it as narrowing a door in a movie theater filled with obese people where the obese people are pain and the door width is stimulation of touch via the limescal tract. If you narrow the door, the obese people would take forever to get out because they are so big and the door is so small. Widen the door (by stop rubbing the effected area) and all the obese people (pain) can exit and pain is recieved in greater magnitude.
first of all i want to thank u very much for such amazing way to present the science.... even there are unrelated vedios to my work,,,, i insist to watch them.... and again thank u,,, hope to see more and more and in dentistry sceince too
Thank you so much for your wonderful presentation and drawing that are extremely helpful. Keep you good work and I believe many people will be benefited from you talented work.
You could've been more specific and could've edged that extra information up the video Pain pathways are ascended through lateral spinothalamic tract and crude touch sensation is through anterior spinothalamic tracts . These fibres ascend in such a way that they are called anterior lateral pathways in general. Pain fibres (Muscle spindle,Golgi tendon organ,pressure receptors ) from the periphery ends up to Substantia Gelatinosa (lamina 2) and Nucleus proprius (lamina 3 and 4) and first order neuron terminates here By the way ,the video was good Thanks
good video...Thanks!! I think Both A delta and C fibres are unmyelinated .they are the lateral division of dorsal root ganglion. On the other hand, A alpha, A beta fibres are myelinated large and belong to medial division of DRG.
Please talk about opiates and mu receptors. Perhaps about how opiates compare to other analgesics as well. And if you throw in why anti-epileptics and certain antidepressants control neuropathic pain? I'd be golden. Thanks for your videos!!
A fantastic overview, both to introduce and help revise the basic mechanisms. Just one question: are you planning to also follow on from this introduction to cover the nociceptor pathways in more detail, e.g. descending modulatory pathways, the role of PAG and lamina II cells?
Excellent video. One minor thing. Melzak and Wall's gate-theory of pain doesn't involve the descending inhibition mechanism but local mechanisms in the dorsal horn . Remember also that pain and nociception are related but different things. Nociception is neither sufficient or necessary to create pain.
good video, however an error was where you labelled the C-fibres and Adelta fibres ascending up the anterior/ventral spinothalamic tract. this is incorrect - they travel up the lateral tract.
Its actually lateral spinothalamic tract that takes pain stimulus to the thalamus..right. You have shown there anterior spinothalamic tract. I think anterior spinothalamic tract carries crude touch and pressure. Is it?
To all people in comments correcting him: According to purves neuroscience 6th edition its anterolateral column of the spinal cord. Its reffered to as the anterolateral system. Probably its not been wrong saying anterior or lateral, but today its anterolateral
all ur vedios are very helpful...!!! Very thankfull to u. Could u plz make vedio to explain Presynaptic inhibition,Descending tract inhibition and Enchephalin interneuron inhibition.
📌MAKE THIS LECTURE STICK: FREE PRACTICE QUESTIONS HERE! 🎓
youmakr.ai/test-playground/questionnaire/673d4b1f859b9c170836f120
Sir I've never - in nearly 30 years of practice in the direct realm of pain- seen a more succinct yet understandable explanation of the ascending pathway .... and in 12 minutes !!!
You Sir have a gift
At first sight the study of human anatomy may appear very difficult. It is tru?e that it is not simple and your studies wont change that. As for being overwhelming, this can be solved if you take it one step at a time. I found an article on Sebs Study Crammer very useful for this.
You explained in 12 mins what my textbook failed to do in 50 pages. THANK YOU!
I had a spinal cord injury in 2000 and I’m still in pain every day. Thank you for posting this video, it’s the best explanation I have ever seen!
I'm a Physical therapist student and your videos are making things much easier. Keep it up!
I liked the way you gave an overall introduction to pathophysiology of pain, and what I truly liked is that you draw structures that can enhance our understanding and give us an insight about where exactly does pain processes happen through numerous pathways
Never realized I was a visual learner till I got to this video. Explained what I've been reading in my book for 4 hours now and not fully comprehending until watching this...Keep doing what you're doing, Sir. You're the real MVP!!!
I appreciate this video as the *survivor of a spinal injury* (L1 compound fracture) resulting in 2 pain disorders (central + CNS pain syndromes) & a related sleep disorder (narcolepsy). I've lived with relentless pain for 14 years, since I was a teenager, & have no hope of achieving any meaningful relief, but I still want to understand as much as I can.
Thank you!!! you made pathophysiology of pain easy to understand in an enjoying manner. The best source of explanation on the whole internet!!!!
I cant ever imagine these type of classes.ur class is amazing ..i like it
This was so perfect for my exam study - I now understand simple things that slipped past me before! Thanks so much! Very helpful.
Wow. I have been looking at diagrams and reading my lecturer's notes for days now and wondering if I'll ever understand it. Thought I'd check youtube for "how to pass pathophysiology" haha and found this instead. In 12 minutes you have become the saviour of my sanity. You are amazing, thank you!
You're amazing! Seriously. So clear, and at just the right speed! Possibly one of the best lessons I've seen on UA-cam! Keep it up! You saved me!
Dude, you are basically getting me through my Univeristy course. I love your videos! **High Five**
I love your videos! I tutor at a junior college, and I use your videos to illustrate what I am trying to explain to my clients. Thank you! Keep making more!
It's soooo clear and simple to understand. Thanks so much!
Great. Thanks alot. May Allah guide you always to the right path 🌷
you are a saviour, I watch all of your videos. Thank you so much.
Wow amazing graphics and explanation. I am currently in a regional anesthesia course and this helped immensely!
Thank you! You just helped me pass my paramedic pathophysiology exam!
Thank you so much! The best vidio about pain pathway in youtube.
I had a lecture on this and felt lost throughout but after watching this I understand perfectly, best summary I've seen. Excellent video.
Really admiring your efforts to make us learn easily,,,
Small correction:-
NOCICEPTORS ARE OF 3 TYPES THOSE ARE
1)A-BETA IN SKIN
2) A-DELTA AND C FIBERS IN SOME PARTS OF SKIN,MUSCLES, VISCERAL TISSUES,
ONE mistake, the spinothalamic pathway for pain travels up the LATERAL branch, not the anterior as shown (touch and pressure are anterior, pain and temp. are lateral), however AMAZING work and I'm learning faster than ever with your work :) a big thanks.
Yes, he did this mistake, please Armando can you correct it? PAIN AND TEMPERATURE ARE LATERAL! thanks
***** Correct me if I am wrong, but doesn't the anterior spinothalamic tract carry pain fibres for everything other than information from the limbs? If I am correct, then this would indeed mean that the information in this tutorial is actually correct!?
I think it's correct for a 'softer' kind of pain only; I'll check again in the Snell (neuroanatomy) once I passed everything :D
pain passes through anterior and lateral spinothalamic tracts both.
Saira Khan crude touch passes through anterior spinothalamic tract. Pain and temprature via lat. Spinothalamic tract
Sir you are really very genius i like this type of classes
Please do a video on the gate theory of pain! :)
I accept what you have written - definately not as easy than some people make out to treat neuropathy at home.
Be cautious and take advice from other people. I searched round many websites and found some expert advice by searching google on sites like Gabs Neuro Guide. Good luck and hope you succeed!
That would take 30 seconds: Pressure and fine touch sensors share the same tract as pain travelling through the spinothalamic tract (either anterior: fast localized or lateral: slow unsure throbbing). Since they converge on the same Dorsal horn on the spine, if you rub a hurt area after scraping your knee, the fine touch Limenscal Tract fires like crazy effectively "taking over" the pathway with more touch going in the dorsal horn than pain. Think of it as narrowing a door in a movie theater filled with obese people where the obese people are pain and the door width is stimulation of touch via the limescal tract. If you narrow the door, the obese people would take forever to get out because they are so big and the door is so small. Widen the door (by stop rubbing the effected area) and all the obese people (pain) can exit and pain is recieved in greater magnitude.
He is soooo good at drawing. It’s so easy to see and understand. I bet he has beautiful notes lol
Genius!!! Artistic!!! Groundbreaking. 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻
You are a lifesaver! Thank you for making this so simple and digestible. Are you really illustrating these? Impressive!
you are just soooooooooooo talented i am just lost for words........
thankyou so much for this
60 mins lecture to explain this was nicely done here within 12 mins.
Your illustration skills are on point my good sir!
very useful and easy to understand especially preparing for pharma exam
Your diagrams are so good.... Excellent with clarity... Thank you so much....
Dude, this video is unbelievable.
Gregory Dunn
yo idk who you are or how i got to your page but shout out to you cuz i was struggling hard core trying to study for my exam tomorrow, thanks homie
Omg! This is wonderful!! Bravo bravo what a fabulous presentation :) my new favorite channel 💕
you really do have a gift! Thank u!
this is a beautiful presentation of the spinothalamic pathway! thank you so much!
Fantastic artwork
first of all i want to thank u very much for such amazing way to present the science.... even there are unrelated vedios to my work,,,, i insist to watch them.... and again thank u,,, hope to see more and more and in dentistry sceince too
thank u it made my prep for class so simple and clear
Thank you so much for your wonderful presentation and drawing that are extremely helpful. Keep you good work and I believe many people will be benefited from you talented work.
Very interesting topic and the presentation is the best.
This video is a blessing
Excellent video! A follow up on the descending pathway would be great.
Thank you to explain very easily and with diagram,god bless you sir .
Education in collages would be much better if teachers like you exist there.
You could've been more specific and could've edged that extra information up the video
Pain pathways are ascended through lateral spinothalamic tract and crude touch sensation is through anterior spinothalamic tracts .
These fibres ascend in such a way that they are called anterior lateral pathways in general.
Pain fibres (Muscle spindle,Golgi tendon organ,pressure receptors ) from the periphery ends up to Substantia Gelatinosa (lamina 2) and Nucleus proprius (lamina 3 and 4) and first order neuron terminates here
By the way ,the video was good
Thanks
Oh god, i'm so grateful for this, you made it so easy to understand I immediately took notes ! thank you!
it was easy for layman to understand. very useful for managing pain
very descriptive and easy to understand plus the visual aid really helped it synapse in my brain!
You should make a video on the neurological differences between physical pain and emotional pain.
Wonderful discussion. Thank you, sir.
good video...Thanks!!
I think Both A delta and C fibres are unmyelinated .they are the lateral division of dorsal root ganglion.
On the other hand, A alpha, A beta fibres are myelinated large and belong to medial division of DRG.
Great video.
Excellent explanation. Looking forward to see more review about pain, like the gate control theory, phantom limb pain etc
Keep it up
very good and concise, well explained
Please make a video on opioids ...your videos are the best in pharmacology
Can some1 explain what opiates are doing to spine?
Please talk about opiates and mu receptors. Perhaps about how opiates compare to other analgesics as well. And if you throw in why anti-epileptics and certain antidepressants control neuropathic pain? I'd be golden. Thanks for your videos!!
Can you explain?¿
Is this why people say lsd fucks up your spine?
so much concept in dis video.... appreciate it👏👏👏👏
it was very helpful.pain is carried by lateral spinothalamic tract.
pain repels itself.
A fantastic overview, both to introduce and help revise the basic mechanisms. Just one question: are you planning to also follow on from this introduction to cover the nociceptor pathways in more detail, e.g. descending modulatory pathways, the role of PAG and lamina II cells?
Excellent video. One minor thing. Melzak and Wall's gate-theory of pain doesn't involve the descending inhibition mechanism but local mechanisms in the dorsal horn . Remember also that pain and nociception are related but different things. Nociception is neither sufficient or necessary to create pain.
Excellent video really really good! awesome stuff
I'm a thai pharmacy student and i wanna thank you about your all of videos. it's easy to understand and remember that!
Thank u so much for this amazing video... ☺️
This video is SO GOOD! So clear and understandable!
Hopefully the next video will be released soon! Looking forward to it!
Thank you!
Great explanation. Can't wait to watch more of your videos.
please do a video on NSAIDs and antibiotics.
good video, however an error was where you labelled the C-fibres and Adelta fibres ascending up the anterior/ventral spinothalamic tract. this is incorrect - they travel up the lateral tract.
Amazing artistic talent !
no words are worthy to thank you
thumbs up 👍
sick video helped me a lot for my physio course, cheers bud.
I really love how you explain all the functions of the human body 👅 thank you 😊 and your drawings, excellent!
YOU ROCK! You kick Khan Academy's butt! Im bout to take Bio-Chem this semester and I would praise you if you could put videos up!
Kick ass...great stuff. I instantly subscribed to your channel!!
thanks for such a awesome explanation.. Greatly appreciated
The way you explain is amazing, thank you so much!!!! 🙏🏼 it was so helpful!
Such a great tutorial video, thanks. Please make a video which is including descenden inhibitory pain pathway. Sincerely, love from Turkey 🇹🇷
Excellent summary . . Thank You !
wow excellent sir best way to explain..love it
Excellent!!!! You should be a teacher at Physio school!
You are amazing!very clear and and and understandable!
I love you vedios!and appreciate your efforts!
Thank you very much
couldn't have made it any more understandable. Thank you loads!
This is fantastic. Thank you for sharing!
Its actually lateral spinothalamic tract that takes pain stimulus to the thalamus..right. You have shown there anterior spinothalamic tract. I think anterior spinothalamic tract carries crude touch and pressure. Is it?
+Pradeep Adhikari yes, lateral st carries pain and fine touch, whereas anterior st carries crude. He made a mistake.
+Nova starr
fine touch carried by dorsal column leminscal pathway not lateral st
Hossam Ashraf
Yes, you right !
To all people in comments correcting him:
According to purves neuroscience 6th edition its anterolateral column of the spinal cord. Its reffered to as the anterolateral system. Probably its not been wrong saying anterior or lateral, but today its anterolateral
Fantastic.. thanks for your great effort..God bless you
superb video, the best one i've seen so far on this subject
You my good sir is a legend! Thanks
wow..i just came for some pain receptors.. am looking forward to listened to ur other videos.very informative. bless u
Keep doing videos please!! They are so helpful!
This made me understand something i feel so complicated. Thank you sir
Ma Shaa ALLAH. great explanation
Thank you Armando!
Simply amazing. Thank you!!!
Your videos r simply awesome
all ur vedios are very helpful...!!! Very thankfull to u.
Could u plz make vedio to explain Presynaptic inhibition,Descending tract inhibition and Enchephalin interneuron inhibition.
Can u plz upload Autonomic pharmacology complete .Your lecture s are so good