Topoisomerase 1 and 2 mechanism

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  • Опубліковано 23 гру 2024

КОМЕНТАРІ • 131

  • @nayanajyothibas706
    @nayanajyothibas706 3 роки тому +5

    The topics are handled so keen that the viewers can again build their knowledge with these lectures as the basement.. Thanks for your passion for a sincere explanation ..

  • @REDROSE-be3br
    @REDROSE-be3br 4 роки тому +21

    Oh my goodness, even class teachers can't explain like this. Thanku so much sir. YOU ARE GREAT

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому +5

      Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @mahathivenkatraman4892
    @mahathivenkatraman4892 4 роки тому +8

    Understanding concepts has never been easier. Thank you so much for making these important concepts so lucid.

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @satabdideka31
    @satabdideka31 4 роки тому +2

    Was trying to understand this for the past 3 days, and today only 17 mins and cleared the entire concept. Sir you are great.

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому +1

      Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @thejuspradeep2105
    @thejuspradeep2105 4 роки тому +1

    Excellent effort from shomu's biology.Thank you very much.Keep going

  • @Lorient121
    @Lorient121 5 років тому +1

    Such a beautiful mechanism. Topoisomerase is the tailor of proteins

  • @sarangas8688
    @sarangas8688 4 роки тому

    During this lock down days , we have online lectures , and your explanation is very helpful to understand our topics 🤗 and we want more pathology explanation

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому +1

      Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

  • @rukhsaryusuf4432
    @rukhsaryusuf4432 5 років тому +3

    In teachers your are all in all sir. Thank you, it was very helpful.

  • @ranganayakinandanavanam7362
    @ranganayakinandanavanam7362 3 роки тому +1

    Very simple and clear explanation. Thank you for making it simple :)

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 роки тому

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @rayanpaul3597
    @rayanpaul3597 2 роки тому +1

    Onek onek dhonyobad aapnak🙌✨

  • @bts_rollercosterlifepurplearmy

    Nobody wants to stress...
    Yes you are my Topoisomerase relese my stress during exam 👍👍

  • @ghazal.m6071
    @ghazal.m6071 2 роки тому

    It is very complete video,thanks.
    I have one question.
    Gyrase convert positive coil to negative?

  • @reshmirajeev5770
    @reshmirajeev5770 4 роки тому +5

    Those ones who disliked this video must be jealous of shomu sir😂😂😂
    You are just perfect teacher sir😊

  • @sayantandas4505
    @sayantandas4505 4 роки тому +1

    Sir thank you very much, you are really a great teacher.

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому

      You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @malikid1000
    @malikid1000 8 років тому +2

    Do you have a video on topoisomerase inhibitors.

  • @lucygomango899
    @lucygomango899 4 роки тому +1

    Sir i really understood this DNA topoisomerase .
    Thnkx a lot of u sir 👏👏💐💐💐
    From.........odisha

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому

      You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @mfbvlog
    @mfbvlog 3 роки тому +2

    Hero means helper that's is shomo sir ❤️

  • @fatezurislam3936
    @fatezurislam3936 Рік тому +1

    Great explanation ,thank you.

  • @mahzaibzehri6523
    @mahzaibzehri6523 5 років тому +1

    A best mentor kindly share your notes of lecturer...

  • @devanggondaleeya4321
    @devanggondaleeya4321 4 роки тому +1

    What is the meaning of negative supercoiling?

  • @jeffgregory2477
    @jeffgregory2477 6 років тому

    You are a very talented teacher my friend

  • @oligoli6209
    @oligoli6209 8 років тому

    nice lecture ....and u make my concept clear during exam .......so tnq once again

  • @shivangitayal7210
    @shivangitayal7210 7 років тому +1

    Thank you very much your lectures were amazing and really helpful

  • @Arya1924-c1z
    @Arya1924-c1z 3 роки тому

    Negative super coil fevour unwind the dna?

  • @kuriyaridhi1867
    @kuriyaridhi1867 3 роки тому

    Thank you shomu sir

  • @DeepakYadav-qr4ic
    @DeepakYadav-qr4ic 4 роки тому +4

    Bro what's your educational qualifications can we know?
    Really comprehensive explanation.

  • @Aakashaganga
    @Aakashaganga Рік тому +1

    Excellent 👌

  • @Young_Carry
    @Young_Carry 3 роки тому +1

    Thank you.

  • @sreenathholla2317
    @sreenathholla2317 3 роки тому

    Hey, so the topoisomerase 1 only involved in the cccdna cellular process, right?

  • @bakhtawarayaz7566
    @bakhtawarayaz7566 7 місяців тому

    Sir, you are phenomenal, sir apki video ky ilawa, mujy kisi aur ka smjh hi nae ata.

  • @Bumble-bee_
    @Bumble-bee_ 2 роки тому

    I cannot find the separate videos of topoisomerase 1 and 2

  • @sonal6662
    @sonal6662 3 роки тому

    Sir Exact Topoisomerase ka function kya h plz in simple language and also tell me about DNA gyrase

  • @malakismail160
    @malakismail160 8 років тому +4

    i have a question. does topoisomerase work only on circular dna or it can work also on linear one? please reply

    • @Drawtine
      @Drawtine 5 років тому

      It can work also on linear one

  • @subhrabanerjee7522
    @subhrabanerjee7522 Рік тому

    Which enzyme removes the supercoiling in eukaryotics?

  • @s2r188
    @s2r188 4 роки тому +1

    Thank You So Much Sir.

  • @shop2012
    @shop2012 7 років тому

    Your videos are very helpful!!

  • @akankshyasamant3310
    @akankshyasamant3310 3 роки тому

    Sir in pathfinder book it is mentioned that enzyme with odd Roman no. After their name are type 1 and with even no. Are type 2, so which is the correct one?

    • @asingh6073
      @asingh6073 3 роки тому

      Yes. I have the same confusion.

  • @vivianebrandao666
    @vivianebrandao666 4 роки тому +1

    this is great, thank you!

  • @CreatorNasir04
    @CreatorNasir04 8 років тому

    what a explanation i can't tell you that.But this video really help me out thank you sir .

  • @ravaliyerramsetty4649
    @ravaliyerramsetty4649 Рік тому +1

    Thank you sir

  • @Priya_P.R
    @Priya_P.R 6 років тому

    No. Topoisomerase type IA comprises 3distinct classes and one of them is topoisomerase III

  • @devanggondaleeya4321
    @devanggondaleeya4321 4 роки тому

    What is the difference between DNA gyrase and topoisomerase IV? In bacteria

    • @shraddhamohapatra9207
      @shraddhamohapatra9207 3 роки тому

      DNA gyrase is Topoisomerase II acting as a swivel to induce negative supercoiling from positive. And topoisomerase IV is responsible for termination of DNA replication

  • @naeemm-m1908
    @naeemm-m1908 7 років тому

    Thank you.Your videos are very helpfu

  • @bhagyasri8878
    @bhagyasri8878 6 років тому

    Sir tqqq soo much your explanation ISS awesome it's easily understood tq for uploading sir

  • @monikaluthra339
    @monikaluthra339 5 років тому +1

    Type I topoisomerase has 2 subfamilies typeIA and typeIB
    Type II topo has 2 subfamilies typeIIA and type IIB

  • @rumpabanerjee445
    @rumpabanerjee445 4 роки тому +1

    Darun bujhiyechho.

  • @nerdnerd4945
    @nerdnerd4945 8 років тому

    love your videos. You are so smart!!Thanks for your videos.

  • @veenamvenkatakrishna7970
    @veenamvenkatakrishna7970 4 роки тому

    Sir why topoisomerase induces negative coiling

  • @nifatjan760
    @nifatjan760 6 років тому

    sir wht iz the reason behind...Passing one strand throug the double nick....?

  • @toheedkhankhan9582
    @toheedkhankhan9582 4 роки тому +1

    Thnku so much

  • @luisfobo
    @luisfobo 5 років тому

    Does topoisomerase come before or after helicase ?

  • @ericfontana462
    @ericfontana462 4 роки тому +12

    9:32 How I feel about my professor who originally made this such a confusing concept.

  • @nifatjan760
    @nifatjan760 6 років тому

    May God bless u....

  • @SURPAHELI
    @SURPAHELI 8 років тому

    very nice thank you sir

  • @marzia9324
    @marzia9324 8 років тому

    Thank u so so so so so much!!

  • @briantham9606
    @briantham9606 5 років тому

    Helpful

  • @hanenalenazi2215
    @hanenalenazi2215 8 років тому

    Thank you

  • @ambrajyaldandi3574
    @ambrajyaldandi3574 6 років тому +1

    Nice language easy to understand

  • @bosonsbotany9934
    @bosonsbotany9934 7 років тому

    sir plz plz plz make a video on sedimentation of pulse label n pulse chase. I'm very confused with this topic :((

  • @devsbiology4808
    @devsbiology4808 6 років тому

    sir pls explain topology..

  • @chandnisingh4526
    @chandnisingh4526 6 років тому

    Thaanks

  • @devanggondaleeya4321
    @devanggondaleeya4321 4 роки тому

    Please use 3 dimension and explain it sir

  • @arshadhussain2083
    @arshadhussain2083 6 років тому

    Thanku.....Suman Sir........💓💓💓

  • @genomelifescience2614
    @genomelifescience2614 4 роки тому

    Good morning sir I am ur old student when I met u in Bangalore there was only 4 students 3girls and a boy(me). I m missing u sir.
    I have a doubt that how dna polymerase distinguishes between dntps and ntps pls tell me sir

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 роки тому

      I remember. How are you now?

    • @thakurankit7159
      @thakurankit7159 3 роки тому

      there are some aminoacids in the nucleotide binding pocket of dna pol(in the palm region of dna pol)called discriminator amino acids which helps to distinguish between dntp and ntps

  • @marzia9324
    @marzia9324 8 років тому

    You are amazing congratulation!!! Really!! I finally understand how they works GOD thanks you MR! you save me!!

  • @archanarangineni5400
    @archanarangineni5400 8 років тому

    ur smart love ur videos:)

  • @uttamkhungurnarzary6958
    @uttamkhungurnarzary6958 3 роки тому

    Watching this video Just for tomorrow Exam

  • @bulmear2531
    @bulmear2531 7 років тому

    good stuff\
    memem

  • @reefelazem2893
    @reefelazem2893 6 років тому

    great,,
    I get it after all

  • @kalpanameena9854
    @kalpanameena9854 7 років тому

    I don't think that is correct... in the second part of the video the primer in the loop…when you imagine you straighten the loop out... than the primers in both chains will be in the same direction….or…leading strand is 5‘ (on the left) - 3´(on the right) so lagging strand is 3‘ (on the left) than on the end of the loop it should be 5‘ ....but primer on it starts also with 5‘…Still thanks for your videos, your teaching helps me a lot!

  • @Rabbu_atal
    @Rabbu_atal 13 днів тому +2

    ❤❤❤❤❤❤❤❤❤❤

  • @mohithinsu4017
    @mohithinsu4017 5 років тому +1

    👍👍👍👍

  • @shaistashah4283
    @shaistashah4283 5 років тому +1

    In Hindi plz

  • @mrscientific4826
    @mrscientific4826 4 роки тому

    Sir plz go deep in topic

  • @abdullahalhariri1379
    @abdullahalhariri1379 5 років тому +1

    I love you Indian 😍

  • @sanjaikumartripathi617
    @sanjaikumartripathi617 6 років тому

    Hindi me

  • @monirssd7073
    @monirssd7073 3 місяці тому

    Kuch koni smj aaya

  • @love2sangita
    @love2sangita 8 років тому

    plz exam in hindi also

  • @فرحهخالد-خ3ي
    @فرحهخالد-خ3ي 3 роки тому

    you better speak hindi.. making easier for both

  • @rudraseth5419
    @rudraseth5419 5 років тому

    Insufficient knowledge.
    Lake of knowledge

  • @malakismail160
    @malakismail160 8 років тому

    i have a question. does topoisomerase work only on circular dna or it can work also on linear one? please reply