Popular Supplements You Should NEVER Take
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- Опубліковано 30 бер 2024
- 9 supplements that I would never take because risks seen in the human trials outweight any potential benefit.
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Here are the links to the research papers referenced in the video:
pubmed.ncbi.nlm.nih.gov/35727...
ods.od.nih.gov/factsheets/Exe...
www.cochranelibrary.com/cdsr/...
www.ncbi.nlm.nih.gov/pmc/arti...
www.uptodate.com/contents/ove...
alz-journals.onlinelibrary.wi...
pubmed.ncbi.nlm.nih.gov/12398...
academic.oup.com/biomedgeront...
ods.od.nih.gov/factsheets/Exe...
www.nccih.nih.gov/health/coen...
pubmed.ncbi.nlm.nih.gov/30580...
www.ncbi.nlm.nih.gov/pmc/arti...
www.cochrane.org/CD011919/END...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/27754...
diabetesjournals.org/care/art...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
ods.od.nih.gov/factsheets/Iro...
pubmed.ncbi.nlm.nih.gov/32690...
ods.od.nih.gov/factsheets/Cal...
www.uptodate.com/contents/cal...
ods.od.nih.gov/factsheets/Fol...
www.sciencedirect.com/science...
www.uptodate.com/contents/low...
www.ncbi.nlm.nih.gov/pmc/arti...
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![I read all [18] NMN Human Studies - 4 Key Findings](http://i.ytimg.com/vi/am2RHcPOaLA/mqdefault.jpg)
Different editing style for this video. Let me know what you think. Hope you like it 🙂
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I just had a rare steak I feel like a million bucks.
Summary:
1 * Direct antioxidants (vitamin A, high dose vitamin C, and vitamin E)
2 * Anti-inflammatory supplements (after a workout) including diclofenac, ibuprofen, curcumin, CoQ10, and pqq
3 * Resveratrol
4 * Metformin (for non-diabetics)
5 * Iron (unless iron deficient)
6 * Calcium supplements (unless you don't get enough calcium in your diet)
7 * High dose folic acid (except for pregnant women)
8 * High dose niacin (nicotinamide riboside and nicotinamide mononucleotide)
9 * Fat burning supplements
The video says that taking these supplements can have a number of negative health effects, including blunting the positive effects of exercise, lowering testosterone levels, and increasing the risk of death, diabetes, and serious infections.
What determines whether a T2D patient who needs medication gets Metaformin or GLP-1?
Great video. I take MicroVitamin and it’s great not having to buy and keep track of so many individual vitamins when microvitamin is them all rolled into one. I have a question though. The serving size is 5, I have been taking 3 in the morning with an omega 3 and then 2 at night. The thought process was to spread out the vitamin intake. Is there any research to show if there is an advantage to breaking up the 5 or is all at once in the morning or all at one at night potentially better?
@@ChuckNorris-lf6vo Based on the current evidence, they are mostly a waste of money.
@@willp9226 what is ? steak ? supplements? give the facts plz.
Direct anti-oxidants (Vitamin A, C, E) right after working out
Anti-inflammatories (particularly after exercise)
Metformin for non-diabetics
Resveratrol
Iron
Calcium
High dose folic acid
High dose niacin
FAT burning supplements (mostly caffeine)
Thank you!
thank u
My Trigeminal Neuralgia stops when I avoid caffeine completely and take 100-300 mg Niacin a day.
What's wrong with resveratrol?
Important to note that with regard to calcium, he said, unless you don't consume dairy.
I take a calcium supplement because I never drink milk, don't often eat cheese and I'm over 60.
For the love of God, Start using timestamps
For the love of God, this should be done by the community.
We need more people loving God
I bet AI could. Idk which one though 😂
😆😆
😂😂😂
#1 direct antioxidants
#2 anti inflammatories after workout
#3 resveratrol
#4 metaformin for non diabetics
#5 iron
#6 calcium supplements
#7 high dose folic acid (excluding pregnancies)
#8 high dose niacin
#9 fat burning supplements (they’re mostly caffeine)
modern hero
Thank you
Thank you! 😊
Thank you!
Thank you for this summary of things Not to take in excess.
Many of these studies are looking at nutrients in isolation. But nutrients have co-factors and work together, right? For instance, some studies showing harm from folate could really be due to B12 depletion, as folate uses up B12. Seems like studies looking at nutrients in isolation should use a well-formulated multivitamin as one of the controls. Maybe vitamins C & E in isolation cause harm, but what about the same amount of those vitamins administered as part of a multivitamin? Is there any evidence that multivitamins blunt the positive effect of exercise?
something similar is niacin, the excretion of nicotinamide requires methylation. Taking large dose of niacin without sufficient vitamin B6, B9 and B12 can quickly deplete methyl groups and elevate homocysteine levels. Also need to mention that all clinical trials showing niacin increasing mortality rate are using the combination of extended niacin plus statin. Taking immediate released niacin alone has been shown to reduce all cause mortality by 11% in the CDP trial.
Please give the proper context for your advice. You claim:
"high dose niacin is associated with an increased risk of all cause death rates by about 10%"
but it should be worded as:
"high doses of slow-release niacin taken with statins is associated with an increased risk of all cause death rates by about 10%"
because that's what meta the analysis specifically cites. Not everyone has access to this paywalled analysis.
Grouping extended release niacin with immediate release niacin is like saying you can compare straight caffeine to extended release caffeine. It's absurd.
With that said, thank you for your very earnest efforts to help the public with accurate and clear nutrition guidance.
Thank you for this clarification. Goes to show you can't believe everything you hear online
This is actually one thing that really annoys me with his videos, because multiple times I've been reading and not just listening to his studies and it says specific information that he glances over and misses and just summarises and it's incorrect because it misses those finer details just like you mentioned.
I pointed this out like you have many times but it keeps happening.
Most of the time he is pretty good, but yeah I've now seen it multiple times so I've lost faith in just listening to what he says without double checking and if I'm doing that I might as well just do the research myself.
That is HUGE, no one from the healthspan extension community recommends slow release niacin afaik - the community has always recommended the flushing niacin at around 250-500mg per day in conjuction with the same amount of TMG (250-500mg). I hope Brad addresses this.
@@TheSydguy30I agree, that is why he is not really a credible source as such, you need to refer back to the study in question
@@TheSydguy30 Dr Brad is doing more harm than good these days with his half baked declarations wrapped with his appeal to authority.
This is outstanding, thoughtful, and well-substantiated. Love your constructively educational content.
Many thanks, Dr. Brad. 💜 And Happy Easter. 🌻
Cheers! Everyone get your boosters and mask up if you have to travel!!
Great video as always 😊
Thank You Dr Stanfield 🙂👍
I find your videos really useful and enlightening. I'm amazed at the number of GPs who also watch your videos and leave comments with medical input below.
You said vitamin A is harmful, but yet you highlighted "beta carotene (with or without vitamin a)". That makes no sense. Are you saying beta carotene is harmful? Because some smoking studies have shown that it is. Vitamin A (retinol, the form from animal livers), taken in safe doses like 5000 IU/day, has been shown to be safe and health enhancing.
Nope
I don’t think he’s going to promote anything animal based 😂
Thank you for joting down your comment. I was going to say the same thing.
Having worked in research and manufacturing in the field of nutrition, one of the problems we'd see is the inferior sourcing of the substance being tested, like retinol.
If retinol is oxidized /rancid from poor storage protocol or from a defective manufacturing process, you're going to see negative outcomes where the outcomes would otherwise be neutral or positive.
This guy is a master shill for his microvitamins.
Thank you for the informative videos and for calling out the overhyped supplements. I have a question and possibly an idea for a video: What is scientifically the best training schedule to improve both your fitness and muscle mass from a longevity focused point of view? How long recovery between sessions do you need? How long should you train? How intense? How much cardio and how much weightlifting? How many sets? And so on. I am currently weight training and also cycling now and then, but I find it hard to balance the two. I also found that longer recovery (like several days) between training sessions lowered my tendency to feel pain in my joints.
Bravo Dr. Brad. I remember when you first started posting videos and you were hyped up about resveratrol, etc. I have learned a lot from watching your journey and it reminds me of all the mistaken beliefs and practices that I have had to discard.
Reasonable video, particularly for such brief coverage of each point for which the standard is being kept. Look forward to the results of metformin in the TAME trial. that said, the primary driver of longevity is lifestyle/behavior/environment related, not supplements or drugs.
Good list.
One supplement I'd love for you to make a video about is Strontium. It drastically increases bone mineral density and reduces fracture risk but studies have shown it increases thrombosis and heart attack risk, and maybe decrease cognitive performance. But those risks are not as cut and dry as they may seem, especially since the risks were fairly small and the strontium used was strontium ranelate which is synthetic vs the naturally occurring form strontium citrate which is used in supplements.
The ranelic acid seemed problematic to me. I suspected it was used for patent purposes
Thank you, Dr. Brad! So glad you're promoting time proven healthy lifetyle and diet over fads and supplements. And have taken the time to show the recearch that backs your position. I started taking CoQ10 a month or so ago on the advice of a friend. Will have to look more clisely ibto it, but reckon this will be the last bottle of CoQ10 I buy.
q10 is amazing. Don´t stop taking it. It has reversed many illness from my parents.
I respect you more and more the further I go down my health journey. Keeping it simple and not trying to fix things that aren't broken is the way to go.
I'm going to focus on diet, exercise and sleep with carefully picked supplements if I need them
Thank you for all the amazing science backed videos you put out!
@DrBradStanfield I've been using MicroVitamins and absolutely love your products. I have a question regarding my lactose intolerance: I've eliminated all dairy from my diet for almost two years now. Should I consider supplementing with low-dose calcium? Additionally, could you recommend a suitable amount of calcium supplements for someone who doesn't consume dairy?
Enlightening.
Good day @DrBradStanfield. Want to know more detailed opinion of vitamin B. A lot of people have impaired vitamin b9/b12 metabolism (MTHFR deficiency and others), for example me and my wife too. And when we take high doses of activated B12/9 forms with TMG, our homocysteine goes down considerably. What would you think in this context? Does decrease in homocysteine outweighs potential risks in papers that you have presented in your opinion?
Thanks!
This is EXCELLENT stuff presented wonderfully
Thanks for the info! How about turmeric? Do the anti-inflammatory effects of turmeric interfere with workout recovery?
Thank you for the amazing content. Do you have any opinions regarding methylene blue?
Hi Dr Brad. I'd like to try MicroVitamin, but it's not available to us in NZ. How can kiwis access it? It's seems such a pity to find a NZ Dr on You Tube, but not be able to access your products. I've heard you say you take the product but shipping does not even allow for NZ to be selected.. I'm a new subscriber so not sure if this has been addressed before. I'd appreciate some help. I'm finding your videos very interesting. Thank you. All the best. 😊
Would you also include astaxanthin in the direct antioxidant category?
Would there be any value to supplementing Vit. A and Vit. E on rest days with no exercise?
Or would you recommend avoiding these completely?
I always look forward to your videos Brad because you give great research driven advice with clear explanations. It is via your videos that I now take NAC and Glycine which has made a huge difference to my asthma. Thank you!
Omega 3 fish oil is excellent for respiratory issues. It reduces inflammation. Best wishes
Ldn is the best for asthma or anything similar. It cured my cat allergies and every other allergy i had. To lower inflammation your should add butyrate, NAC, LDN, Omega 3, EsterC. Its probably the best combo ever. I also believe aspirin does have some benefits but it can be dangerous. You can switch it with white willow bark extract which is as good if not better than aspirin.
Hi Dr. Brad!
can you clarify? I take Niacinamide for good skin. Is this a safe form ?
I thought it was different from other forms of B3 .
Thanks so much!
What are the sources of these studies? Not shown. Are they reliable?
How can taking calcium supplements contribute to kidney stones- when consuming oxalic acid foods together with calcium, actually prevents the stone formation?
@DrBradStanfield: Looking at #1, what is your option on supplementing Spirulina and Chlorella?
Another great video. I just want to ask, since NAC causes indirect antioxidant, is it okay to take glynac let's say 2 hrs after exercise?
Seconded. How long after exercise should these be taken?
Does cod liver oil fall under vit A category?
I have this question too! hope Brad sees it
@@eduardorocha2345Dr Brad has gone rogue! He promotes his products and slams anything else. Vitamin A and E used in studies were synthetic not natural .
Not really, its a whole food source i believe
A and E I think
Isnt NAC also a anti inflammatory? Even if it isnt, would non direct anti oxidtives not impact workouts?
Dr Brad love your content and greatly respect your opinion as a medical professional. What would you say to someone whose quality of life (physical, mental/cognitive, sleep, energy, endurance) has been greatly enhanced by NMN? Would you attribute the increase in quality of life to something else? Do you recommend not taking it all, despite these perceived/experienced benefits?
So how long after exercise is it fine to take anti-oxidants? (5hours, 1 day, 2days...)?
Isn't CoQ 10 useful in preventing migraine coupled with magnesium glycinate and riboflavin?
This is interesting. I would have thought that, if one were deficient in a vitamin or mineral, due to either dietary deficiency or poor absorption, they should supplement that vitamin or mineral, but I guess not. Edit: oh, you address this about iron, but it seems like there's a typo in your title-it contains, in order, the letters "N," "E," "V," "E," and "R" (capitalization in original), which, together, spell "never."
However when I take Amla & Cordyceps several hours before exercise, I can push my exercise much further. (Amla is high in vit. C ) It helps my overall energy and breathing.
Just finished Radiation treatment on a skin cancer and will be using Liposomal glutathione for a few weeks till I heal up and will then resume Glynac. What are your thoughts?
Liposomal glutathione ? that compony ..so hard to find good one
@@vladislavroytapel2830 I use renew by science
Why are you taking nicotinamide instead of niacin, and why 50mg (for what purpose?)? Is 50mg of nicotinamide the same as 50mg of niacin, or is there some kind of loss through the body's processing of nicotinamide into niacin?
In regards to the antioxidants I was wondering if the negative affects are still seen if you get these from food sources instead of supplements?
Does that mean we shouldn't take multivitamins (without iron) with small amounts of vitamins across the board? Or are those low amounts okay?
TY Brad- I have recently stopped the high dose Niacin which, to be honest, is a relief from flushing and itching every day. So that is Resveterol and Niacin that were popular amongst us pill popping age freaks that have dropped off the recommended list. Funny how goes sometimes.
I'm only interested in following up on one research paper that you mentioned. I've no idea how I'm supposed to find it in that list. Could you at least put a 2-3 word summary of the issue/molecule that the link is looking at.
I have big doubts that a trial followed two groups of non-diabetics - taking placebo and Metformin - for 21 years.
So should I stop taking Nutritional Yeast? Vitamin B3 has been shown in some studies to decrease issues with the eyes.
I think vegemite counts as food
No you should not stop. These days DrBrad is really doing more harm than good
@@MNTrader2012you have to think of things through his lens; as a doctor he can't in good conscience recommend something that doesn't have good data behind it, even if he personally believes something might work
Stop everything according to brad
does calcium akg count as a calcium supplement or is that ok to take? im taking it for the longevity benefits and not for regular calcium uses.
This is my favorite channel for supplement information. My only disagreement is with the vitamin C recommendation in the case of older people (above 50). There is some evidence that absorption and cellular intake of vitamin C decreases with age. Personally (I'm 65 years old) I take 250 mg of vitamin C in the morning and at the end of the day (total 500mg).
This amount does not seem to blunt training benefit. I can still get good improvement from training using this small amount of vitamin C. Cuts and bruises heal better with this small additional amount of vitamin C and I also feel better. Of course this is anecdotal but repeated attempts at stopping the vitamin C have always brought problems for me despite a good diet. This is my personal experience.
However, people should be careful if using an Iron supplement (if a blood test reveals a supplement is needed). Avoid taking vitamin C along with an Iron supplement. Take them at separate meals.
I agree younger people on a good diet might not need this but you really need to eat fresh fruits and other good food sources of vitamin C.
No one should ever take folic acid. Folate is a different story.
Read this too, Then I read, there’s Noo difference in Manufactured Folate and manufactured Folic Acid!
Who really Knows? !
Thank you! 😮
@@mystrength5640 where did you read that?
Could you please explain why?(why folic acid is harmful?)
@@Zmeyuka1A quick search through the Literature will provide details. UA-cam does not allow links in comments.
One does not simply write that without elaborating.
What is considered as a "high dose" of Vitamin C?
Horbäach Vitamin B-100 Complex looks exactly like the doses of your Multi. The Horbäach Vitamin B-100 Complex has twice the dosage though. I guess it is because they went for 100% and you went for 50% of RDA. The price of Horbäach Vitamin B-100 Complex is $12.06 US and they will split in half with a pill splitter. I am trying to figure out why you went above the RDA on Niacin. Is this why?
It would be fair to mention that Niacin daily dose was 1-3 mg in the first study and in second study niacin was given in combination with laropiprant, and the side effects could not be associated with one molecule only, researchers noted this right after the thex you highlighted. Also, worth mentioning that laropiprant that was developed to reduce Niacin flushing side effects, never passed third phase clinical studies and was abandoned for human use.
Hey Dr Brad can you take a look at bergermet supplements and see if they are worth taking, thanks
resveratrol lowers testosterone in women with PCOS, that`s not a harm that`s a benefit
Women also require some measures of testosterone
@@RCV2024 I didn't say they didn't but PCOS is generally characterized by the ovaries producing too many androgens and treatments which reduce male hormones in PCOS are described positively
If you dont eat meat and dont get enough vitamin A - retinol from your diet shouldn't you supplement with vitamin A? Isnt it bad to be deficient in vitamin A?
I use a fish oil called "Möller's Tran" that contain both vitamin A and vitamin E. Are you saying that using this product would be worse than not using it?
No. Take your fish oil. I think Dr Brad is doing more harm than good these days.
I buy your vitamins. The bottle says take 5 a day. The website says 150 day supply. Am I missing 4 bottles from my order or is your website saying the wrong thing?
I have Iron overload a count of 777 which is being looked at by my doctor (I hope to have a course of phlebotomy) The Liver function test revealed my alt's were 265 - 300 (normal is between 20 and 40) however, taking Milk thistle and produced wonders and lowered my ALT's to 27. I have a slight Raise in cholesterol' any supplement recommendation to keep this in check (I have moderated my diet but still a little high..
You do not want to exceed recommended daily allowance due to possible harm. But there is definite and serious harm at below the RDA, and many people at RDA will not be getting enough. This is an asymmetrical risk curve. And many the the RDA were or are vastly too low, such as the 1.25 hydroxy D3 that for almost the entire last 60 years had a lower limit of 15 ng per ml, a ridiculously low and utterly unhealthy level for 100% of us. I agree with you a many of these, especially iron and calcium and creatine monohydrate. I tend to vehemently disagree with your RDA approach, and use risk curves and blood tests to guide.
RDA is the minimum requirement to prevent harmful effect from deficiency. RDA is not the max limit. If he is telling people not to exceed RDA then he is dead wrong.
@@MNTrader2012yeah. Typically I know he tries to be as accurate as possible but it feels like this one he just reasoned his way through.
The RDA is set at levels designed to meet the needs of 97-98% of people.
would be interested in hearing your take diet/exercise/supplement for peri-post menopausal women. We all know to eat protein and lift weights. My doctor actually told me to take a calcium supplement.
Disappointing news with Resveratrol. Does it still have any place in supplementing? Recovery, later life supplements? Interesting video!
There's nothing wrong with resveratrol. Most people take too high of a dosage and you need fats or liposomes to even absorb any of it since it's fat soluble.
How long should you wait after a workout to take a low dose multivitamin?
Cod liver oil is loaded with vitamin A. Safe to take?
Yes.
I am going to disagree on calcium. If I do sauna and / or heavily exercise which is daily, I will cramp without calcium. I take up to 57% of the RDA through supplements. Furthermore, the brand / type I take showed no increase in CVD in one study
A total of 300 postmenopausal women were randomly assigned to daily supplements of 800 mg of Ca (2·4 g Aquamin) (Ca), 800 mg of Ca with 3 g of scFOS (CaFOS) or control (maltodextrin) (MD). A full lipid profile, body composition, blood pressure and a range of cytokines were measured at baseline and after 24 months. Intention-to-treat ANCOVA assessed treatment effects between the groups. At the 4-year follow-up, there was no significant difference between the groups for reported diagnosed cardiovascular
Cronin BE, Allsopp PJ, Slevin MM, Magee PJ, Livingstone MB, Strain JJ, McSorley EM. Effects of supplementation with a calcium-rich marine-derived multi-mineral supplement and short-chain fructo-oligosaccharides on serum lipids in postmenopausal women. Br J Nutr. 2016 Feb 28
Of course, I am not a woman, but that's the only study on acquamin on point. Plus acquamin does appear to improve bone health in other studies.
Yeah but that study was funded by the brand's manufacturers so some scepticism might be warranted.
@@tomgoff7887 True, though one would hope a University run double blind RCT would not be tainted.
@@jackbuaer3828 Yes but researchers are usually aware that unless study results are acceptable, funders are unlikely to provide further funding in the future. It would be worth therefore looking at the study design. I haven't done that but I note they they discuss results compared with the control group rather than baseline. Given that the placebo was maltodextrin, it's possible that maltodextrin has some adverse effects on eg lipid levels.
Lots of omega-3 (fish oil) supplements contain vitamin E (to prevent the fat from oxidizing). Should we be concerned about this?
So if I need to take Metformin for pre diabetes and calcium for osteopenia, what time of day can I take them to not blunt the positive effect of exercise? It’s already being blunted by statins
I am so confused on resveratrol. One study says it lowers test in women, others say it has no effect or may actually increase testosterone in people. Anybody taking it and reach conclusions on how they feel???
If I've been using niacin (niacinamide) 250mg for 2 years without any side effects should I switch up to a lower dose or NMN/NR?
No, you should double or treble the dose. If you are not turning purple in the face and ripping your shirt open at the collar, you are not getting an effective dose.
@@TheDavidlloydjones LOL
@@willp9226 It isn't funny because Niacinamide is recommended for those with actinic keratosis.
What about ASTAXANTHIN ???
(It’s a powerful antioxidant that I see Siim Land recently recommending)
what about A from Cod Liver Oil and E from wheatgerm oil? Essentially "food" sources of each.
the issue with iron is iron comes with folic acid which ia helping foe homocysteine and this is confusing for who dont know how to help with homocysteine like take B6 B12 folate...
Hi Doctor - checking on why not add micro dose amount lithium to vitamin. I’m suggesting the amount one would get from just drinking water type in couple counties in Texas. Here much less risk of depression and other neurological diseases. And much other clinical research on benefits via mechanisms for this very very small amount of lithium in range of 300 micrograms. Would ever consider? Thanks
Next year all of the statements will be reversed due to NEW research!
Hehe
is ubiquinol better than coq10?
This is implying you shouldn't eat aot of fruit and vegetables after working out because it will blunt the muslce building process. Any thoughts?
What can I use to replace metformin for PCOS treatment?
How about taking L-Methyl Folate (form of Folic Acid) for individuals with depression especially in those who have genetic predisposition to slowly metabolize folic acid?
My multivitamin has 100 mg of calcium derived from algae. Is this a concern still?
Nicotinamide is being used in multiple studies around the world, supplementing at 3 milligrams a day for the positive affects on Glaucoma patients. The dosage is massive compared to the daily RDA. I have Glaucoma and have been considering this, but your comments were a huge bummer! Heart attack or go blind, which will it be?!!!
What does this mean for eating an orange after exercise. Still ok or?
YEs of course it is. I swear, these days Dr Brad is doing more harm than good.
Is high dose melatonin 300 mg anti cancer effect? And many people take it 300mg after radiation and before petscan. Dr Stanfeild could you please answer this question? Please
Great video. Thanks. MicroVitamin... I don't like tablets and believe that bovine or veggie caps are superior concerning disintegration and absorption.
Happy Easter Brad. God Bless New Zealand. Thanks for all your hard work & research. You have saved me $1000's in useless supplement these past few years.
Dr Rena Malik posted a UA-cam video two years ago on the benefits of high dose Folate.
Is the research she presented now outdated?
I’ve been taking Methylfolate thinking it’s a good thing😬
Hi Brad. You don't mention how much Niacin are you currently taking. Could you please share, since it seems you've lowered the amount?
Yerp. His initial videos was much higher Niacin recommendation paired with TMG (I remember because I started using it in stead of NMN) and suddenly in this video he has dramatically dropped his usage to 50mg…
I don’t watch all his stuff but missed this 🤨
@@CvdWalt100 But I think he mentions 50mg of nicotamide, which I think is not the same as nicacin. It seems like he has stopped Niacin altogether.
Very nice video with useful information, however I suspect the issue is more complicated... I think the context in which one takes supplements or medications plays a role and this context is not fixed. For example, when I get sick (virus) I use large doses of amino acids and certain vitamins and as a result I get over the virus within 6 hours.
The same if I exercise or get very tired (I use whey protein and creatine), but if I am fasting to induce autophagy I use stressors to deepen autophagy and apoptosis.
Generally there is no fixed prescription.
And let's not forget that many of us who follow you aim not only for good health but for exceptional longevity and unfortunately we even experiment with the risk involved in that experimentation.
Hi @DrBradStanfield, please also consider the use of High Dose Vit. C on a gut-microbiome perspective. There can be benefits. I have seen studies that show benefits of increasing Bifido with Vitamin C
What about the vitamine E that is IN omega3 pills? What is your opinion on that?
I mean... It is in all of the omega3 pills to prevent oxydation
What about Cod Liver Oil? Is it harmful because it contains Vitamin A?
Never trust someone giving advice on supplements who also sells them.
what about antioxidant befor exercise ?
Why is there NO shipping to Thailand?
Dr ...what is the high dose if vitamin c?
High dose he showed was 1g
I question the need to put TMG in the multi vitamin formula. That specific ingredient is not at all good for certain individuals and can cause a range of very unpleasant side effects.
Can you address the supplement C15 (fatty15)?
It's hard to get the recommended amount of vitamine A equivalent with plant-based diets tough (you'd need to eat lots of very special fruits or spinach each day). Is a vitamine A deficiency thus prefereable to supplementing with a seemingly appropriate dose, i.e. one that takes you to the recommended level? I wonder which doses these studies were using. In the first one the dose of vitamine E was much higher than anything you would reasonably supplement.
Also I'm not convinced about avoiding anti-inflammatory supplements. After all, just as many others, I have the problem of inflammation in my body, to the point that I cannot even do intense sports, because it makes me feel sick and stressed out. So the worry of getting not enough stress by training seems like a joke to me. I also had a quite massive CoQ10 deficiency. For some reason my body fails to produce the amount needed. So why would I not want to supplement it? If doesn't prevent heart disease really doesn't matter. My intuition would tell me that I can support the body best by consuming lots of antiinflammatory components, but of course not including medications with side effects. Am I wrong?
Finally, do we really need to wait, until we lose our hair due to an obvious iron deficiency? The study you've shown only advices against iron supplemented in doses more than about two times what the body needs daily. Again, more relevant would be the question, if I'm not reaching my recommended intake of iron, is it beneficial to supplement with, say 6 mg to reach the recommended intake? However, if the RDA is too high and people with higher iron have lower life expectancy, shouldn't we avoid eating foods rich in iron as well?