The David Sinclair $720,000,000 Train Wreck!

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  • Опубліковано 9 бер 2024
  • This is the story of how Harvard professor David Sinclair's mistakes earned him $720 million, and is using the same strategy to do it again, today.
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    Here are the links to the research papers referenced in the video:
    www.ncbi.nlm.nih.gov/pmc/arti...
    pubmed.ncbi.nlm.nih.gov/12939...
    pubmed.ncbi.nlm.nih.gov/15254...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.ncbi.nlm.nih.gov/pmc/arti...
    pubmed.ncbi.nlm.nih.gov/15254...
    www.ncbi.nlm.nih.gov/pmc/arti...
    pubmed.ncbi.nlm.nih.gov/15684...
    pubmed.ncbi.nlm.nih.gov/19843...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.ncbi.nlm.nih.gov/pmc/arti...
    HTTPS://PUBMED.NCBI.NLM.NIH.GOV/32755...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.frontiersin.org/articles/...
    pubmed.ncbi.nlm.nih.gov/28182...
    www.cochrane.org/CD011919/END...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.ncbi.nlm.nih.gov/pmc/arti...
    pubmed.ncbi.nlm.nih.gov/27754...
    www.uptodate.com/contents/lip...
    www.regulations.gov/document/...
    www.newsweek.com/new-suppleme...
    / 1764361555557380198
    / 1764436536693567778
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КОМЕНТАРІ • 1,6 тис.

  • @DrBradStanfield
    @DrBradStanfield  2 місяці тому +164

    What do you think about the statement from the former Dean of Harvard Medical School at the end of the video?
    📜 Roadmap - how to look young & feel strong: drstanfield.com/pages/roadmap

    • @jozefwoo8079
      @jozefwoo8079 2 місяці тому +3

      Dr Stanfield, will you be distributing in Europe as well? Currently the customs and transport costs for MicroVitamin are insanely high.

    • @augurcybernaut4785
      @augurcybernaut4785 2 місяці тому +12

      8:08 😖
      🤔 are we to understand that GSK bought WITHOUT evidence of efficacy? Without replicating ANY experiments? Wouldn’t that imply Sinclair wasn’t the only one “incompetent”?
      What about all those OTHERS advocating for resveratrol ?
      And no I didn’t take the 💉🦠
      🫣Wouldn’t GSK have sought the opinion of his colleagues before or even now to do a “claw back”?

    • @jodihammer
      @jodihammer 2 місяці тому +20

      @@augurcybernaut4785 right. How can they afford to spend $720M without doing proper due diligence?

    • @srlm8215
      @srlm8215 2 місяці тому +6

      you also have to have this point of view: if you have to spend thousands for each specific study, it would cost millions, it's not just the studies, I've been taking nmn for 4
      month, when I take it sublingually I immediately feel the effects, there is a boost, the effects are there, there is no denying it, do we have to spend thousands more to show the immediate effect that it provides ?

    • @danielmccarthyy
      @danielmccarthyy 2 місяці тому +2

      Damning.

  • @lordjim3109
    @lordjim3109 2 місяці тому +1339

    David Sinclair is by far the worst disappointment in the longevity community. He started as a great hope for so many, and ended up as the embodiment of all that is wrong with modern science: greed and corruption.

    • @loum.4377
      @loum.4377 2 місяці тому +25

      money grab.

    • @mitkoogrozev
      @mitkoogrozev 2 місяці тому +31

      That's not intrinsically a problem with science or people, but the fact that we live in a monetary based global society. Money has become a generalized reinforcer. That is, it can affect and control behavior for absolutely all aspects of life since it's been inserted in all of them , while naturally without money different aspects of life have distinct and varied reinforcers instead of a singular generalized one. As such, money has a stronger effect than all others, and/or at least it will always, as long as it exists, corrupt anything and everything it's involved in. And well, it's involved in...everything :D .
      And "corrupt'' is probably not even the right word, since what it does is just an intrinsic property of it's mechanisms. So it behaves as expected (at least by the people who know what to look for, and not be blinded by ideology of how they THINK it's supposed to work) . In other words, the system is not corrupted, it works exactly as designed. Any time you insert a token to replace intrinsic motivation (intrinsic motivation meaning doing a task simply because of it's results, or in other words because you enjoy it/believe that is important etc.) , you introduce a skew for the behavior to be done for the extrinsic motivator - the token instead. And we have just one singular token called money, that can be exchanged for anything and everything put into all areas in life. So naturally, everything will be skewed.

    • @Utoko
      @Utoko 2 місяці тому +27

      Ye he is a great communicator. Got me interesting in the field with his book+ great interviews and at the same time makes me distrust now every single person in the field.
      Boundless greed is so sad.

    • @lordjim3109
      @lordjim3109 2 місяці тому +6

      @@Utoko Exactly so.

    • @gugy68
      @gugy68 2 місяці тому +12

      Sad indeed. I never spent any money on his stuff but was an avid follower of his information and the guy looked extremely credible.
      No wonder all institutions and most scientists in this case are so discredit and looked with skepticism. They dug that whole and honestly I don’t think they will ever regain the trust from the public again.

  • @abc_cba
    @abc_cba 2 місяці тому +516

    This man will be an international level threat to David Sinclair, calling him out, the only one who dares who do that!

    • @ThatBritishVlogger
      @ThatBritishVlogger 2 місяці тому +14

      A risky call out to say that his intentions were to trick GSK though

    • @nephilimninjaofnibiru2907
      @nephilimninjaofnibiru2907 2 місяці тому +11

      For someone who studies lifespan. This seems like a rookie mistake to shorten one's lifespan.

    • @zack_120
      @zack_120 2 місяці тому +7

      ​@@ThatBritishVloggerNo, he didn't. you got the logic messed up.

    • @davidjordan2011
      @davidjordan2011 2 місяці тому +11

      In fact, he's not the only one. Marcel James, through his YT channel The Pulse, is doing similar, although he also criticizes the FDA.

    • @abc_cba
      @abc_cba 2 місяці тому +12

      @@davidjordan2011 well, as for India, Stanfield is a popular name in the health community, so, I'm saying based on my geography and whereabouts and people I interact with.
      That's just why I used the term "international" level. 🤣😅
      UA-cam has become a space for misinformation these days, especially fear mongering.
      There are two Aussies, Labmuffin (Michele) and Brad Stanfield who bust the myths and tell us not be scared which people like Gundry, Dave Asprey and a few others use to create furore amongst the "uneducated masses" who barely know any science but just follow fads to stay relevant in this age of Instagram.

  • @UsDiYoNa
    @UsDiYoNa 2 місяці тому +253

    Harvard has really become a joke.

    • @ninefive8930
      @ninefive8930 2 місяці тому +20

      All of modern academia really is a joke. Back to reading Plato and Aristotle.

    • @LoisoPondohva
      @LoisoPondohva 2 місяці тому +10

      Harvard has been "not a joke" for a very brief period very long ago.
      People just associate it with being elite because 95% or our billionaires and politicians have graduated from there. But being elite is not the cause of that one, being corrupt is.

    • @oolala53
      @oolala53 2 місяці тому +1

      @@LoisoPondohvainteresting statistic. Care to say where you found it?

    • @beardfootofficial
      @beardfootofficial 2 місяці тому +1

      Truth

    • @justrecorded4u984
      @justrecorded4u984 2 місяці тому +6

      Harvard is hype and doesn't have much contribution to science.

  • @traderalex655
    @traderalex655 Місяць тому +5

    As a scientist myself, I'm very distressed about the lack of honesty and integrity in many areas of science. Harvard is a cesspool and an embarrassment to the scientific community. We need a national, independent oversight organization who reports to the public on people like Sinclair. Thank you for making this video.

  • @wpmitra7251
    @wpmitra7251 2 місяці тому +632

    Any time I see Sinclair associated with any supplement or treatment, I immediately stop paying attention to it. I wonder why Harvard doesn't severe ties with him already. Kudos to you

    • @kimberlybarrett5341
      @kimberlybarrett5341 2 місяці тому +14

      Agreed

    • @googlespies
      @googlespies 2 місяці тому

      Harvard is beyond corrupt themselves. This isn't the first time and it won't be the last time Harvard has been intwined in blatant science fraud. Search "50 Years Ago, Sugar Industry Quietly Paid Scientists To Point Blame At Fat"

    • @dominikh9526
      @dominikh9526 2 місяці тому +50

      Same with Huberman.

    • @indiankid8601
      @indiankid8601 2 місяці тому +20

      Because Money 💰 🤑

    • @slimturnpike
      @slimturnpike 2 місяці тому

      Goes double for Huberman ​@@dominikh9526

  • @AncestralFuel
    @AncestralFuel 2 місяці тому +328

    Finally someone has exposed this fraud. I have heard of bits and pieces of the Sinclair con over the years, but this is the first time I have seen it all tied-up in a single report. Great job Dr Brad!

    • @paulbarclay4114
      @paulbarclay4114 2 місяці тому +1

      he has a long history of fraud, but the work he is currently doing is game changing

    • @AncestralFuel
      @AncestralFuel 2 місяці тому

      @@paulbarclay4114 yeah that is what everyone was saying before

    • @peters616
      @peters616 2 місяці тому +8

      fool me once...

    • @AncestralFuel
      @AncestralFuel 2 місяці тому +3

      Yeah, I recently saw a study out of Britain illustrating in 65-80 age group they could raise their NAD levels to that of a twenty year old by having them simply walk 13,500 steps a day - Sinclair ain’t talking about this study. 4,000 steps nothing, 8,000 steps were an improvement, but 13,500 was the magic number.

    • @swimbait1
      @swimbait1 2 місяці тому +1

      There’s hundreds of videos online calling out Sinclair.

  • @jamgamber0
    @jamgamber0 2 місяці тому +58

    No surprise why David Sinclair didn't want to debate with Dr Brad in the past. Great work Dr Brad. Cannot thank you enough. Couldn't stop laughing at each comment debunking Sinclair.

  • @bornholm1588
    @bornholm1588 2 місяці тому +79

    In Germany we also have a that time famous doctor who wrote books about "forever young" with great success in which he claimed he could expand lifespan with lifestyle and nutrition. Now he is almost 80, still alive, but looks just like all 80 year olds I know.

    • @cag1
      @cag1 2 місяці тому +4

      who is that?

    • @davidogan
      @davidogan 2 місяці тому +3

      Maybe that famous doctor meant it metaphorically? Like being “forever young” inside?

    • @rajeevshrivastava4488
      @rajeevshrivastava4488 2 місяці тому +6

      Deepak Chopra is in the same category....

    • @AL_THOMAS_777
      @AL_THOMAS_777 29 днів тому

      @@cag1 Dr. Ulli STRUNZ !

    • @philosopher2king
      @philosopher2king 27 днів тому +2

      The only "Forever Young" out of Germany was that song from Alphaville and I love it 😁

  • @travv88
    @travv88 2 місяці тому +629

    Disturbing. Longevity science is too important to tolerate frauds like this.

    • @Nelis1324
      @Nelis1324 2 місяці тому +19

      Absolutely. It wastes so much time, money and health.

    • @Nelis1324
      @Nelis1324 2 місяці тому +19

      Perhaps he is actually incompetent, not seeing the flaws and believing his own crap. But the blatant lie would make that seem very unlikely.

    • @janissquirell5072
      @janissquirell5072 2 місяці тому +3

      not for reptilians 😮

    • @eggbenedict-gt7mw
      @eggbenedict-gt7mw 2 місяці тому +1

      Bcoz it's very important nobody takes part in it

    • @simonwiltshire7089
      @simonwiltshire7089 2 місяці тому +5

      It’s nearly all fraud

  • @OdysseuesCotton
    @OdysseuesCotton 2 місяці тому +346

    Dr. Standfield, I was being critical of your first video concerning David Sinclair, but in the meantime I feel informed well enough to understand better what Sinclair is actually doing. I apologize to you. This video is great and sheds a light on Sinclaire's misdoings. Thanks a lot for that + greetings from Germany

    • @Chaotic313
      @Chaotic313 2 місяці тому +19

      I was right there with you! I was upset at him throwing shade on a product I was so invested in taking. He stuck to the science and not the hype to the benefit of us all.

    • @LauraPazzaglia
      @LauraPazzaglia 2 місяці тому +14

      Yes, me too. I feel he has held steadfast and become a better communicator. The early days of defensive tweets and such are gone - I now realize he was very passionate about the topic and took it personally. Now he's letting the facts speak for themselves. Again, good job Dr. Brad!

    • @Vgallo
      @Vgallo 2 місяці тому +4

      @@Chaotic313 no no you’ve got it wrong, the first accusations were not enough to discredit Sinclair- who after all is the one that came up with the information theory of aging and is a legitimate scientist cited in academic journals all the time, this one accusation was enough to throw shade but not totally discredit the man, especially when you haven’t got the other side of the story, so it wouldn’t of been rational to join the cynical bandwagon at that point, not just based on Stanfield evidence anyway, perhaps if you yourself had insider info, but if you didn’t, then it would of been overly cynical and irrational to join in Stanfield chorus.
      Fast forward to now, with all the water under the bridge and these new accusations and Stanfield initial position seems far more plausible, but only after this added data, not before, so don’t trick yourself into thinking it was any kind of misguided loyalty to a product- I mean did the product work? Surely if anything the efficacy of the product played a larger role on your rationale, or at least I would hope so.
      Regardless, Sinclair is still the creator of the information theory of aging, something the whole longevity field uses, so even if he is a dodgy businessman and a liar, it doesn’t preclude him from being able to contribute valid scientific findings, I mean look at the guy that was part of creating the mRNA vaccine who went around telling everyone it was a massive con when Covid hit, to make money for himself, then when he got Covid and got really sick himself he begged drs to give it to him, does that mean he didn’t do important work that contributed to the amazing mRNA vaccines? Of course it doesn’t.
      Don’t confuse ethics and intelligence. Something Stanfield does consistently.
      Also Stanfield is totally wrong about nad boosters, the fda is studying nad boosters to see if it can be made into an affordable medicine for everyone, they did a similar thing with nac, Stanfield was deliberately vague on all this, all he said was “ Sinclair lobbied the fda” and “ now he’s doing the same thing again”, didn’t explain why the fda is studying nad boosters and when he covered nad boosters on his channel, he excluded all the high quality studies that showed real efficacy of nad boosters.

    • @grellis6483
      @grellis6483 2 місяці тому +3

      ​@@Vgallo I have a bridge in the desert I think you'd be interested in buying.

    • @Vgallo
      @Vgallo 2 місяці тому +1

      @@grellis6483 cynicism isn’t clever or rational.

  • @SrNutritivo
    @SrNutritivo 2 місяці тому +39

    This breaks my heart. I loved his book and literally re-started my life, took me out of a severe depression, and transformed my life in a positive ways. I totally bought his messianic vision about our future. Hurts so bad that looks like all that was based on a lie 😢

    • @jmonkey1111
      @jmonkey1111 2 місяці тому +14

      Looks like some of his science checks out as he wasn't the first to research nmn and metformin. The resveritol is the no go it seems

    • @pgc6290
      @pgc6290 2 місяці тому +2

      .

    • @pgc6290
      @pgc6290 2 місяці тому +1

      ​@@jmonkey1111have they verified the research that he is doing in harvard. He said age reversal pill might come in 10 years.

    • @erikhenze2339
      @erikhenze2339 2 місяці тому +18

      Don’t be entirely discouraged. He may be somewhat of a snake oil salesman, but he is not only that. His information theory of aging is a very interesting insight and, while still nascent, there is some experimental evidence for it now. But only time (further experiments) will tell if it’s really a breakthrough theory.

    • @matthiasl3807
      @matthiasl3807 2 місяці тому +11

      You have changed your life to the better. No one else. Even if the basis were a fraud or a lie: you changed it and you have done something good. I can understand your words better than most people. Believe me. But hold on to those positive changes you have made!

  • @danpictish5457
    @danpictish5457 2 місяці тому +64

    Just being from Harvard shouldn't mean anything without evidence!

    • @No-Humans-Allowed
      @No-Humans-Allowed 2 місяці тому

      Harvard is one of the biggest collaborators with big Pharma. They have published ‘peer reviewed’ fraud to suit their narrative and not to be regarded as a leading light in honesty and integrity.

    • @shellderp
      @shellderp 2 місяці тому

      they are the ones who admitted to being funded by sugar industry to lie about results. They also recently came out with the hilarious article about red meat being linked to diabetes

  • @Vincent-fv1ch
    @Vincent-fv1ch 2 місяці тому +269

    This video needs to go viral!

  • @mikecain6947
    @mikecain6947 2 місяці тому +222

    You are very brave to do this video. Thank you and keep them coming.

  • @reuterss306
    @reuterss306 2 місяці тому +50

    More people need to hear this. To me its mind-boggling how many people are still chugging down absurd amounts of overprized resveratrol. Didn't help that many people praised the studies and talked about it so much on podcasts. Like Dr. Rhonda Patrick on JRE.

    • @comatosebrose
      @comatosebrose 2 місяці тому +5

      I think I've been conned uve spent thousands of both nmn and resveratrol.

    • @rg3412
      @rg3412 2 місяці тому

      She knows it’s more lucrative to spit back positive results from one study than to deconstruct the many studies that inundate the papers and whose majority are not reproducible

    • @nichobee
      @nichobee 2 місяці тому

      She annoys me too. I think she means a lot more well than Sinclair, but she also overstates the importance of many individual biochemicals, and in essence she overcomplicates the process of living a healthy and normal life

  • @viveviveka2651
    @viveviveka2651 2 місяці тому +34

    Thank you for covering this.
    I fell for Sinclair's NMN recommendations. It is the one supplement that really made me nauseated. So I lost a few days to the nausea, and wasted some money.
    Shame on Sinclair, and shame on Harvard. Lesson learned.

  • @earx23
    @earx23 2 місяці тому +135

    Thanks for exposing Sinclair's fraud. At some point I thought he was sketchy. All we needed was some solid proof. Thanks for this detailed review.

    • @earx23
      @earx23 2 місяці тому +7

      @@fdsfaf132 Come on. Even in the last couple of years Sinclair claimed that his findings were going to lead to extended life span in humans, still hanging on to the supposedly beneficial effects of Resveratrol, which were disproved long ago. He doesn't even admit his mistakes.. just riding the wave to even more money.

    • @HkFinn83
      @HkFinn83 2 місяці тому

      @@fdsfaf132 you’re not disagreeing you’re using the word legalistically, he’s using vernacular

    • @jacked_asian
      @jacked_asian 2 місяці тому +2

      When he hyped up autophagy and low protein diets, I just felt very offput by him

    • @morganmiller7777
      @morganmiller7777 2 місяці тому

      He’s biased as hell. Nobody knows anything. The good doctor here just needs an agenda and it gets him UA-cam clicks. Who is capitalizing ???

    • @morganmiller7777
      @morganmiller7777 2 місяці тому

      @@jacked_asianautophagy is real, not sure about low protein, though research for many years have pointed to some benefits of lowering protein at least in short cycles

  • @thefinalroman
    @thefinalroman 2 місяці тому +157

    David Sinclair uses a filter in all his livestreams to look younger 😂

    • @infiniteawareness69
      @infiniteawareness69 2 місяці тому +2

      xD

    • @suzannecase6170
      @suzannecase6170 2 місяці тому +5

      The filter actually exists already as part of zoom. Everyone on zoom has much better looking skin than in reality.

    • @C2C.
      @C2C. 2 місяці тому +13

      @@suzannecase6170 The default setting is no filter. You need to turn it on, which Sinclair clear did.

    • @suzannecase6170
      @suzannecase6170 2 місяці тому +1

      👍

    • @mixalis6168
      @mixalis6168 2 місяці тому +4

      Filters and in person looks frail ~

  • @hitmusicworldwide
    @hitmusicworldwide 2 місяці тому +33

    All of these glaring issues could and should have been brought up by GSK scientists before the deal was made. Let's not leave out the incompetence on the GSK side. 720 million is a lot to put on the table without rigorous scrutiny.

    • @rolletroll2338
      @rolletroll2338 2 місяці тому

      Money is cheap for certain people. They think they can manipulate those amounts of money without the scrutiny needed. Too bad for them.

    • @mzie25
      @mzie25 2 місяці тому

      That would mean access to secrets before payment. Not going to happen. 😢

    • @LetterSignedBy51SpiesWasA-Coup
      @LetterSignedBy51SpiesWasA-Coup 2 місяці тому +1

      ​@@mzie25secret studies that had already been published?

  • @carma23
    @carma23 2 місяці тому +13

    I don’t know if NMN activates sirtuin 1 or not, but there’s no doubt it’s helping me with my chronic fatigue. I would strongly recommend that you don’t paint things black and white

    • @annhughes9912
      @annhughes9912 2 місяці тому +1

      Yes, my husband and I have noticed a distinct improvement in energy levels on NMN

  • @Chaotic313
    @Chaotic313 2 місяці тому +101

    Dr. Brad, this was such a great video!! I was a Sinclair disciple, drinking the snake oil. The first video I saw that cast doubt on what he was preaching was one of yours a while back. Thank you for your well researched, clearly stated information always.❤

    • @olddouchebag
      @olddouchebag 2 місяці тому

      Nearly all of the health people on podcasts are conmen who have "the secret" to something.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 2 місяці тому +4

      It's not quite as clear or exactly as Dr Brad is saying. Resveratrol and NMN had a history of benefits long before Sinclair was on the scene and backed up by science. Sinclair seems to have created dodgy experiments focusing on sirtuins, however it's still not necessarily quite as Brad sees it.

    • @korozsitamas
      @korozsitamas 2 місяці тому

      @@paulharrisonadventuregearm5457so rare someone is brave enough to oppose the angry mob

  • @Hack3r91
    @Hack3r91 2 місяці тому +68

    I too fell for the NMN hype a year ago, fortunately I kept doing research and dropped it before sinking too much money in supplements. Thank you for being a voice of reason.

    • @horrorcoder
      @horrorcoder 2 місяці тому +9

      This has nothing to do with NMN

    • @myscreen2urs
      @myscreen2urs 2 місяці тому +1

      I tried it for 6 months. NAD levels didn't move one bit

    • @Pyriold
      @Pyriold 2 місяці тому +5

      @@myscreen2urs NMN raises NAD, but only in pretty high doses. Dr. Lustgarten confirmed that in a self test. Usual niacin was more effective though.

    • @myscreen2urs
      @myscreen2urs 2 місяці тому +2

      @@Pyriold when is a dose considered pretty high? I was taking 500mgs with TMG

    • @Pyriold
      @Pyriold 2 місяці тому +4

      @@myscreen2urs I think when he took 300mg it had no effect but 1.5 grams raised NAD significantly.

  • @tonyseektruth
    @tonyseektruth 2 місяці тому +93

    Many of us have known for years that David is one of the most incompetent and unethical people in the longevity space. He really should be arrested and charged for what he has done to companies and their innocent investors, and for placing so many lives at risk.

    • @Drgluee
      @Drgluee 2 місяці тому +3

      I agree. Many of the big investment firms that provide retirement plans invest in pharmaceutical companies.

    • @tonyseektruth
      @tonyseektruth 2 місяці тому

      @@Drgluee Exactly, it seems David doesn't care about the poor victims and their retirement plans seeing they had invested into the companies that David tricked.

    • @JoeRogansForehead
      @JoeRogansForehead 2 місяці тому +6

      “Innocent investors”😂

    • @tonyseektruth
      @tonyseektruth 2 місяці тому

      @@JoeRogansForehead Yes, there were a lot of innocent investors into GlaxoSmithShine who lost a LOT :(

    • @TheDavidlloydjones
      @TheDavidlloydjones 2 місяці тому

      @@Drgluee
      That doesn't make any sense at all, clueless Gluee. Life extension is the last thing people who "the big investment firms that provide retirement plans " want.
      If I were them, I'd be investing in driverless busses. Glider clubs for over-40's. Radical new forms of Scuba gear.
      And especially the famous balsawood fire escape. "Avoid the clanging sound of peole running out of your building." "Rustless protection!" "Even faster from the upper storeys!!!"

  • @andrewtaylor9799
    @andrewtaylor9799 2 місяці тому +9

    Thanks for publicizing this.

  • @bobkristiansen2704
    @bobkristiansen2704 2 місяці тому +214

    I don't trust any longevity researcher who undergoes cosmetic surgeries. It's so easy to go back and see David Sinclair gradually lose facial movement. He looks like a doll.

    • @zoeydeu2261
      @zoeydeu2261 2 місяці тому +40

      THANK YOU for pointing that out!! I've mentioned this countless times on other videos and his fanboys attack me, saying I don't know what I'm talking about, and that his "youthful" appearance is 100% due to his longevity supplements. I pointed out his frozen line-free face as classic overuse of use of botox, but they refuse to believe. My friend who's a cosmetic surgeon agrees when she sees videos of Sinclair!

    • @vinaynagaraj4638
      @vinaynagaraj4638 2 місяці тому +14

      I'd say you shouldn't trust longevity researchers who undergo cosmetic surgeries and don't declare it. Botox has positive correlation with lifespan (thesis is that looking younger makes you want to take care of yourself more, or people who invest in botox probably care about their lifespan).

    • @bobkristiansen2704
      @bobkristiansen2704 2 місяці тому

      Sure, I agree. I wouldn't have minded as much if he'd stated he had it done every time people told him he looked great in interviews.@@vinaynagaraj4638

    • @vaivaivaiful
      @vaivaivaiful 2 місяці тому

      @@zoeydeu2261 To be honest, in order to look or younger than your age you actually need cosmetic procedures. I mean if looking YOUNGER is your goal, not just being healthy. Lots of people are living in this belief that they will look young just because of their lifestyle, but that is rarely the case. That being said, it is important to disclose if you're getting something done, which Sinclair didn't do. I saw one of his speeches in some health conference (easily available on youtube). And he showed his before and after pictures. On the after picture he said " I think my protocol is working". He showed before picture with forehead wrinkles and after WITHOUT forehead wrinkles. Now this is a scam!!! As a dermatologist I can tell you that no lifestyle protocol, no supplements will erase forehead wrinkles that already exist and are this deep. This made me realise he is a liar actually.

    • @liviusss
      @liviusss 2 місяці тому +6

      ​@@zoeydeu2261Honestly he doesn't look that youthful though...

  • @nicksutton2964
    @nicksutton2964 2 місяці тому +100

    Slippery Sinclair and his Sirtuin

  • @micahkaneshiro9267
    @micahkaneshiro9267 2 місяці тому +2

    Your channel is a shining light. Thank you for being so conscientious.

  • @curtasher9110
    @curtasher9110 2 місяці тому +8

    Thank you for posting this, Brad

  • @mikect05
    @mikect05 2 місяці тому +106

    Doctor Stanfield you are L E G E N D

    • @SilhSe
      @SilhSe 2 місяці тому +6

      Doc Brad is L E G E N D 😁😁

    • @abc_cba
      @abc_cba 2 місяці тому

      tu kaha se hain?

    • @mikect05
      @mikect05 2 місяці тому

      Good people need other food people 💪🏽🙏🏻

  • @helge666
    @helge666 2 місяці тому +75

    Personally, I've been getting a Snakeoil vibe from Sinclair for years. Didn't even finish reading his "Lifespan" book, because something feels off with it, too. Can't even put my finger on it. I've talked to others about it, but nobody seems to agree with me. However, I trust my own BS detector, and it's buzzing when I see the good Professor talk.

    • @zozzrc
      @zozzrc 2 місяці тому +15

      Yes, this.
      Sinclair does not talk like a scientist. He often speaks in absolutes and seldom qualifies his statements with the key phrases of "needs more study", "we need to be careful not to extrapolate etc.'" He almost never cites other studies and often relies on antidotes . After listening to thousands of hours of longevity podcasts one begins to sense when someone is interested in science vs someone who is interested in marketing. People who are imprecise in their language are usually imprecise in their work. I love youtube , but I try always to keep in mind this Feynman quote "The first principle is that you must not fool yourself and you are the easiest person to fool."

    • @larsnystrom6698
      @larsnystrom6698 2 місяці тому +4

      That book was too much fiction for me. Ideas put forward as if it were science, but very little scientific support for them.
      Much like he nowadays claim that cells has a epigenetic "backup copy".
      It's not easy for real researchers to debunk the claims of a charlatan with too much media support.
      Harvard seems to like that kind though.

    • @Crowgirl22
      @Crowgirl22 2 місяці тому +2

      Me too, I always got a bad vibe from him, yet everyone always touted his work

    • @catb4918
      @catb4918 2 місяці тому

      I agree! I never liked him & thought it was all B.S.

    • @ronschapf4561
      @ronschapf4561 2 місяці тому

      I felt the same way and stopped following him after a while.

  • @justusklocke7783
    @justusklocke7783 2 місяці тому +4

    I follow you since years and have huge respect for your courage!! Keep up your great work!

  • @ChickenDinner13
    @ChickenDinner13 2 місяці тому +8

    This is the best video you’ve ever created… Thank you so much for putting all of this together

  • @Ronlawhouston
    @Ronlawhouston 2 місяці тому +44

    I'm not against people online who sell products. I am, however, immediately skeptical of their motives.

    • @ThomasAT86
      @ThomasAT86 2 місяці тому +1

      Yeah I'd agree with that. I think being skeptical is great when it comes to things like that. Sadly there's a lot of people who'll say that anyone who wants to sell something is a fraud, typical lack of nuance, and black and white thinking.

    • @user-iz9zb6zh4f
      @user-iz9zb6zh4f 2 місяці тому

      I would agree, what I have come to understand about the good guys and the bad. Is both need money, however the good guys try to tell the truth to the best of their knowledge, they also try to make something safe and useful to the people while charging an affordable or decent price that everyone can afford. Where as the bad guys care not if their product is safe or what lies they must tell to sell it, and they try to charge the highest possible price they can to rip you off in the name of profit. Just the basics there but seems to be the universal pattern of such.

  • @mac2658
    @mac2658 2 місяці тому +42

    Four years ago Sinclair with his scientific credentials and his father's wonderful story of second youth convinced me to buy alot of nmn, metformin and resveratrol, I took it for a couple of weeks and gave me headaches, I threw it all in the garbage can. Eat well, exercise, manage your social and mental health, that's it.

    • @HkFinn83
      @HkFinn83 2 місяці тому +4

      Maybe that’s the best you can do now, but hopefully there will someday be a supplement that really does work. If not there isn’t much hope for the longevity field, none of the diets seem to do much beyond what just being moderately lean do and exercise, while good, is difficult to link with any real profound results

    • @dencentbeatz794
      @dencentbeatz794 2 місяці тому +1

      @@HkFinn83living that healthy lifestyle is proven to really help you live longer and healthier.

    • @HkFinn83
      @HkFinn83 2 місяці тому

      @@dencentbeatz794 yes I know obviously. In the longevity space we are looking and hoping for something more significant than the marginal life expectancy impacts that have been demonstrated by certain diets/calorie restriction and vo2max training etc. and of course a molecule that actually works is our main hope.

    • @HkFinn83
      @HkFinn83 2 місяці тому +1

      @@dencentbeatz794 yes obviously, and those us who practice calorie restriction and try to increase our vo2max etc and are hoping for something more significant and that has actual profound longevity impacts, a molecule that actually works is our main hope.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 2 місяці тому +3

      Not quite as simple as that I'm afraid. Sinclair wasn't even the person who discovered the longevity health benefits of all those. There is other totally independent research that backs up the benefits that have nothing to do with Sinclair.

  • @djlouder
    @djlouder 2 місяці тому +19

    Thank you for staying on top of this subject! I especially appreciate your take on B3. Since watching one of your past vids, I started to take B3. It has helped me immensely! Thanks for all you do!

  • @GodMode-xv6sw
    @GodMode-xv6sw 2 місяці тому +6

    Excellent work Brad. We support your noble quest.

  • @Will-no6te
    @Will-no6te 2 місяці тому +56

    WOW, great exposé! Thank you so much for your ongoing committment to truth in a world oversaturated with mis/disinformation.

  • @grahamw453
    @grahamw453 2 місяці тому +15

    Wow. Thanks Brad for this quality video. You are truly courageous for doing this. Thanks for getting the word out about Sinclairs history.

  • @C2C.
    @C2C. 2 місяці тому +3

    Thank you, Brad for staying on top of this and updating us. I subscribe to your channel for your evidence-based approach. You demonstrated integrity when you initially questioned him a couple of years ago and was met by his insults; and you remained steady and professional. It's not easy to call out someone considered a luminary by many. I applaud your intellectual honesty and courage throughout!

  • @AndrewPawley11
    @AndrewPawley11 2 місяці тому +5

    Wild! What a story! Thanks for making the video!

  • @marcjames3487
    @marcjames3487 2 місяці тому +62

    Hopefully all the other influencers will stop giving him space to aggrandize himself. One thing I've learned in business over many decades is never deal with people who lack integrity. I spotted that fatal flaw in David Sinclair from the beginning. Kudos to the academics calling him out.

    • @olddouchebag
      @olddouchebag 2 місяці тому +7

      Influencers thrive on having all these health grifters on their podcasts.

    • @kathleen9456
      @kathleen9456 2 місяці тому +4

      The Pulse has basically made his entire channel around NMN 🙄

    • @Livelovelaugh684
      @Livelovelaugh684 2 місяці тому

      @thepulsechannel is piggy backing his 15 minutes of fame around the hype of nmn. He can’t back down now. He feels relevant with the attention he’s getting. He disappears otherwise.
      For the record. I mix in nmn with other supplements. But I’m realistic about its use. It simply cannot and doesn’t do everything he claims it does on his channel. His anectodal claims are out of control.

    • @pcaul8156
      @pcaul8156 2 місяці тому

      He's just one more grifter in a circle-jerk sea of narcissistic podcasters who pick a niche and try to bleed it dry of cash

    • @upstar21t
      @upstar21t 2 місяці тому +1

      How'd you spot it?

  • @ccdub15
    @ccdub15 2 місяці тому +21

    I followed Sinclair years back, but i had my reservations about him when he shared that he was a vegan and ate only one meal a day, which woukd leave anyone malnourished.

    • @MsYoutuebchen
      @MsYoutuebchen 2 місяці тому +8

      Not necessarily.

    • @mimimoon6082
      @mimimoon6082 2 місяці тому +2

      he's vegan now because of his girlfriend. He was a meat eater and shared that in past interviews.

    • @Fearzero
      @Fearzero 2 місяці тому +4

      You clearly have no clue about plant based diets.

    • @canesugar911
      @canesugar911 2 місяці тому

      Any diet not well curated can make one malnourished.

    • @Franky2A3
      @Franky2A3 2 місяці тому +3

      I think the one main meal a day works. Been doing it for years since I was a kid, before DS talked about it. No Breakfast, no Lunch just some fruits during the day and a reasonable dinner. I'm 70 and people say I look very young , no meds, no health issues. MBI=22.5 BP =100/70

  • @thegreaterconundrum
    @thegreaterconundrum 2 місяці тому +3

    This video is so important! What gives misinformation such power is that scientists and thinkers choose to say nothing about it, wether because they think it's obvious or because they assume people already know. But I love that you're calling him out, and I'd love more videos going into bad research practice and calling out specific papers/individuals for this kind of shady misconduct. No one else is going to do it, and if no one does it it'll just get worse and worse!

  • @maxentropy0305
    @maxentropy0305 2 місяці тому +5

    Thank you for bringing this up! The truth (or scandal) needs to be exposed more.

  • @jimmybaker4821
    @jimmybaker4821 2 місяці тому +10

    Amazing video brad. Love when u focus on the facts and science

  • @gospelofthomas77thpearl22
    @gospelofthomas77thpearl22 2 місяці тому +2

    Thanks for your honesty. Much appreciated 👍🏼

  • @percocetzh
    @percocetzh 2 місяці тому +3

    Good stuff on calling stuff like this out!Appreciate you Dr. Stanfield keep up all of your amazing work

  • @jfp17
    @jfp17 2 місяці тому +16

    “The issue is Sinclairs’s incompetence/genius.”
    It’s a fine line between the two.

    • @aexetan2769
      @aexetan2769 2 місяці тому

      So David Sinclair is dichotomous.

    • @bartl.7390
      @bartl.7390 2 місяці тому

      The genius of playing dumb or he's just incompetent.

  • @0effort
    @0effort 2 місяці тому +13

    what a pleasure to watch a video backed up by facts and cross-references. well done Brad!

  • @camer0nwiz
    @camer0nwiz 2 місяці тому

    Thank you so much Brad for making this video!!

  • @richardgabbrielli3328
    @richardgabbrielli3328 2 місяці тому +8

    Great video Brad, thanks for sharing this info as many are still not aware of what Sinclair's doing

  • @andymilkowski7682
    @andymilkowski7682 2 місяці тому +10

    Thank you for this thorough review.

  • @bigbear7567
    @bigbear7567 2 місяці тому +21

    Thank you for informing us.

  • @tracyau9122
    @tracyau9122 2 місяці тому +2

    Wow. I wondered when someone would comprehensively put it all together. Thankyou - great piece!

  • @LauraPazzaglia
    @LauraPazzaglia 2 місяці тому +2

    Well done, Dr. Brad. I have watched you from the beginning and you have finely crafted and refined your way to communicate key issues, as well as taking a stand and not just talking the talk but walking the walk (with your supplement). I appreciate your sharing your expertise in such a concise fact-base manner . Thanks to your videos I have lowered my Vitamin B complex supplement from one that contains 1000%'s of the daily values to a more reasonable amount. Ciao from Italy, L

  • @loum.4377
    @loum.4377 2 місяці тому +6

    Thank you for taking this on and calling out bs!

  • @BCIQW
    @BCIQW 2 місяці тому +2

    Thank you for making this video!

  • @jamiesaari
    @jamiesaari 2 місяці тому

    You have soooo much courage and are appreciated more than you know. Thank you 🙏

  • @tdeprins
    @tdeprins Місяць тому

    I have been following you for a couple years and I got deep respect for your courage, your overall style and approach. You balance your videos that include some promotions in a way that is appropriate, staying true to science. Respect!

  • @sallypilcher6761
    @sallypilcher6761 2 місяці тому +51

    Looks like Elizabeth Holmes transitioned and is calling herself David Sinclair!

    • @canesugar911
      @canesugar911 2 місяці тому +4

      David has been running this scam since lizzy was in highschool

    • @astar1147
      @astar1147 2 місяці тому +2

      lmao

    • @pgc6290
      @pgc6290 2 місяці тому +1

      But as soon as someone makes unreal claims, shouldnt they be most highly scrutinized. He has been in public eye since yearrrrrrssssss.

  • @JohnyRelax
    @JohnyRelax 2 місяці тому +13

    Thanks, Brad, I used to follow Sinclair, you saved me.

  • @blackgoldeneye
    @blackgoldeneye 2 місяці тому +1

    Now I’m even more grateful for your channel.

  • @patriciastark7292
    @patriciastark7292 2 місяці тому +2

    Thank you for your courageous post!

  • @jamesleadley7872
    @jamesleadley7872 2 місяці тому +34

    Hard to believe Harvard isn't investigating this and looking to revoke his position. I know it's a long hard process but it's got to start.

    • @annwilliams6438
      @annwilliams6438 2 місяці тому +1

      Unfortunately Harvard seems to be having a problem with ethics lately.

  • @metamind095
    @metamind095 2 місяці тому +8

    This needs to be brought more to the public attention. Sinclair should not get away with this level of fraud and deception!

  • @karldean2
    @karldean2 2 місяці тому +1

    Thank you for keeping it real. You are my go-to doctor for health advice.

  • @always.wondering.wandering
    @always.wondering.wandering 2 місяці тому +5

    Wow! Thanks so much for sharing this.

  • @cktam5670
    @cktam5670 2 місяці тому +5

    thank you Dr. Standfield.

  • @JohnSmith-mr1wg
    @JohnSmith-mr1wg 2 місяці тому

    Outstanding investigative work. Thanks, Dr. Brad!

  • @gryphonschnitzel7140
    @gryphonschnitzel7140 2 місяці тому

    Thanks for your videos and effort, you truly are doing humanity a great service by doing what you do. S tier youtube channel.

  • @miltonmartins8217
    @miltonmartins8217 2 місяці тому +6

    very informative!! great video!!!

  • @Mom_Luvs_Tech
    @Mom_Luvs_Tech 2 місяці тому +5

    Thank you so much for this.

  • @patriciaort9172
    @patriciaort9172 2 місяці тому

    Thanks for this update.

  • @kellicardaras2805
    @kellicardaras2805 2 місяці тому +1

    Excellent and important video! Thank you!

  • @brendant3979
    @brendant3979 2 місяці тому +17

    Great informaion, thank you

  • @Proximo.
    @Proximo. 2 місяці тому +3

    Absolutely excellent video.

  • @Kaimelar8
    @Kaimelar8 2 місяці тому

    Thanks for making a video about this, I think it's important.

  • @gstlynx
    @gstlynx 2 місяці тому +1

    Thanks , great timeline presentation.

  • @sverkermansson1744
    @sverkermansson1744 2 місяці тому +7

    Thanks for your research 🔬 🎉

  • @LidiYaFilms
    @LidiYaFilms 2 місяці тому +7

    thank you for your great work

  • @rolandsaucier1006
    @rolandsaucier1006 2 місяці тому

    This is the kind of video that makes me happy that I am a subscriber. Well done.

  • @Tron-Jockey
    @Tron-Jockey 2 місяці тому

    Outstanding. Thank you Dr. Stanfield.

  • @Mikolas649
    @Mikolas649 2 місяці тому +3

    New respect for Dr. Brad, for bringing all the facts, and cutting the BS!

  • @rockhard9690
    @rockhard9690 2 місяці тому +5

    thank you for informing us

  • @wusnheilus
    @wusnheilus 2 місяці тому +5

    Thank you @DrBradStanfield! Such information is rare on YT.

  • @SharonPitman
    @SharonPitman 2 місяці тому +1

    I applaud you for putting yourself out there 👏🏻 Without people like you, we are none the wiser. After I came across your videos a while ago, I immediately stopped taking many of the hyped longevity supplements and saved myself a lot of money. I love simplicity, I love common sense and your videos just resonated with me. Thank you, again, Brad. You are making a real difference by creating some clarity to such complex topics and oftentimes ambiguous data. You’re awesome 🙌🏻

  • @adamscottv
    @adamscottv 2 місяці тому

    Dr. Brad keeping it real. You're doing good work.

  • @user-kz5ch3gr2b
    @user-kz5ch3gr2b 2 місяці тому +6

    In regards to NMN I just turned 60, Ive been on it for about year...NO QUESTION it works I hope they don't get rid of it as I can see and feel the result of taking it.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 2 місяці тому

      NMN and resveratrol were never connected solely to Sinclair. The benefits of both were found long before Sinclair. It's wrong to simply state resveratrol is toxic...the research isn't clear on this. We know niacin is connected with longevity and mental health...long before Sinclair

    • @fannyalbi9040
      @fannyalbi9040 2 місяці тому +1

      u r taking expensive form of vitamin B3 😂😂😂

    • @user-kz5ch3gr2b
      @user-kz5ch3gr2b 2 місяці тому

      @@fannyalbi9040 Perhaps you should do more research Doctor....

    • @user-kz5ch3gr2b
      @user-kz5ch3gr2b 2 місяці тому

      @@fannyalbi9040 Dear Doctor Fanny please do some more research intro it...

    • @morganmiller7777
      @morganmiller7777 2 місяці тому +1

      @@fannyalbi9040then you don’t understand why it’s different.
      There’s absolutely no solid proof of anything at this point, and no ways whatsoever to debunk or dismiss anything about NMN..not yet.
      The doc here is on an emotional ally biased mission, in spite of his good efforts to stay robotic on UA-cam.

  • @buck8055
    @buck8055 2 місяці тому +3

    Thank you Brad for having the guts to make this video. Hopefully, Sinclair and company won’t use some of their ill gotten gains to try and take you down. Keep up the good fight!

  • @byarnneil1916
    @byarnneil1916 2 місяці тому +1

    Great job on your research, people need to know. Much Respect. 😀

  • @ankaerjavec9616
    @ankaerjavec9616 2 місяці тому

    Thank you for making this video! 🙏

  • @BaneTrogdor
    @BaneTrogdor 2 місяці тому +7

    As soon as i saw him, something about him screamed FRAUD!

  • @billbimson2408
    @billbimson2408 2 місяці тому +10

    Yep, I got duped by the NMN saga. Spent a lot of money on it. I bought 6 months worth of NMN and TMG (Beltain). It did nothing for me so the 'experts' on UA-cam told me that I had too much CD38 and would need to take Apigenin so that the NMN could perform its magic. Bought a months worth of that and there was still no effect from it. When I posted this on UA-cam, people started saying I should take it with Oleic acid or other supplements. How many additional supplements are you supposed to take to get this crap to work??? The thing is, there are so many people on UA-cam explaining how they have wonderful results from it. Surely they can't all be lying?

    • @robcrawford1799
      @robcrawford1799 2 місяці тому

      Actually yes, they can all be,lying. Though I suspect many experience Placebo effects.

    • @Fearzero
      @Fearzero 2 місяці тому +2

      I feel nothing physically from 1g daily for 4 years but my memory is super sharp still at 53.

    • @streetspiritlondon
      @streetspiritlondon 2 місяці тому +2

      It’s changed my life

    • @electricpurple4112
      @electricpurple4112 2 місяці тому

      He's not even talking about NMN here no? lol

  • @jonathanantoine4962
    @jonathanantoine4962 2 місяці тому +1

    Thank you for your courage and ethic

  • @deel2435
    @deel2435 2 місяці тому

    Don't let the haters get you down Dr Brad! Keep up the great work.

  • @alfredhammerer3902
    @alfredhammerer3902 2 місяці тому +4

    Great research and on point ! I had done my own little research on this guy and came to the exact same conclusions. Bravo also for the courage to stand up against this guy !

  • @ericoshea9382
    @ericoshea9382 2 місяці тому +7

    Outstanding analysis and extremely well-timed! Hopefully it will inform consumers as they consider “longevity” supplements such as NMN.

  • @LjudmilaLevy-ml8dh
    @LjudmilaLevy-ml8dh 28 днів тому

    Thank you for your research, Dr Brad; people need to hear this information.

  • @chefty88
    @chefty88 2 місяці тому +1

    Love your content Dr. Brad, keep up the good fight and don’t be deterred by the machine. Stay independent and realistic.