Apart from one viewer who had nothing positive to say about this episode, we have only heard positive comments. While this is nice, it's also a bit surprising. HA is one of the most frequently used cosmetic ingredients and our recommendation is to NOT use it if you have intact skin. Where are all of the HA supporters?
I am so happy that you have just validated how I have personally found HA to be not tolerated by my skin & could not understand the hype & results that everyone is talking about. I always found it dehydrating and sensitising to my skin. Luckily I understand my skin quite well & can see what it does and doesn't like & act accordingly. ...despite various hypes. My only frustration is, that it is genuinely hard to find skincare without HA jammed into it. Or my other nemesis squalane, which also is not tolerated by my skin as it always makes me break out. Actually, I would greatly appreciate a deep dive into squalane. I just randomly came across this video & you certainly got my attention! Thank you for making me feel not crazy ❤
My skin reacts the same way to HA but interestingly, the same with squalene. I thought I was an anomaly with the “bio-identical” squalane; I wonder what the connect could be. 🤔
I have also specifically had reactions to HA and squalane! (And it’s so hard to find products!) And I know it was HA and squalane specifically because I used pure HA with just a natural, gentle preservative and I had a reaction to it and then much later used pure squalane and got a horrible rash. I wonder if being sensitive to both is related.
@@JamiLaundryme too with both HA and squalane! I thought it was just me but I see two other people on here saying they had reactions to those specific ingredients as well
@@surrendertoflow78 HA will create sensitivity by making the skin susceptible to antigens. It could be something in the environment, not in your skincare regimen. Then the small fragments of HA feed the sensitivity reaction.
Mary Schook was one of the first to bring this up and she was practically villainized by the industry. HA absolutely inflames/irritates my skin and completely dries it out on another level, especially lower molecular weights. I’ve even purchased $100+ bottles and it’s the same inflammation/dryness every time. I don’t understand how this is a holy grail ingredient for so many and it’s literally in EVERYTHING. When I found Mary a few years ago, I dropped the HA and my skin did a 180. Thank you for both for creating additional awareness!
It was Mary who first clued me in. Idiot that I am, it took me a year to remove HA from my product. I am sorry to hear that Mary got sh$t for her views. It’s important to have respectful debate.
Can you mention some of the true and tried products you love ? I too want to find effective products for my aging dry skin but it seems everything has them 😒😒
Thank you so much. I had a client complain that she felt her skin being drier after using HA, and now I understand! I love all this clinical information so I can do my best for my clients. I've looked through all my products and most of them have it as an ingredient.
Dr Shereen Idriss had a video on HA channeling the same sentiments. I always wondered why my skin looked more dry after putting my HA sunscreen when I reached the office and the problem immediately disappeared once I ditched all HA containing products. I now only use high molecular HA serum when I microneedle every couple of months and that's it.
Such great information! And I now feel validated. I had the same experience where my skin would become more irritated and drier after using hyaluronic acid in any form. Thanks for getting this information out there. More people need to be aware of the negative side effects.
Thank you for bringing awareness to one of the most ubiquitous topics in the skin care industry. I appreciate the research and science that went into presenting the information and video. Thank you.
Thank you Ivan! this also plays greatly into the whole filler debacle. All that hyaluronic acid that is injected into people - causing all types of inflammation and therefore aging in people. Blessings
Thank you for this information. I noticed that HA left my skin dry feeling after it dried as opposed to the glycerine and water mix that I usually use. I've heard similar things about glycerine but my skin always feels moist and looks plump after using it. I live in a desert btw. Mix it with rosewater in the right ratio and there won't be any tackiness.
I believe in your research, Ivan! But, I really wonder how those people who use retin A tighten their face! I have witnessed those. I stopped it coz it dried my skin badly.
I’ve had reactions to HA before and now I’m realizing it might have been due to it sensitizing my skin over time. Thank you so much for this. I know Adipeau doesn’t have HA in it (which I am thrilled about). But that is something I don’t use as a moisturizer on my whole face (it works wonderfully for increasing volume, just don’t use it as a general everyday moisturizer). It’s SO hard to find anything else without HA for mature skin. I also had a reaction to pure sugar cane squalane as did another commenter. I wonder if there’s any connection to having reactions to both HA and squalane? It’s also getting very difficult to find moisturizers without squalane, which seems to be the next big hype. 1) Does anyone have any HA-free (and squalane-free) recommendations for daily light moisturizer? 2) Are there any other ingredients that help peptides get into the skin that aren’t damaging or should we be ignoring the peptide hype as well? Thank you!
Also curious about (1). If a product has propylene glycol listed in the top 5 ingredients, then you should watch out for that. But HA is really a penetrant of choice because most people -- including the dermatologist referred to -- don't know that it's a penetrant and assume that it's doing something positive.
How is it with hyaluronic acid filler? It would be very interesting to know, I still find it works very well if it's not overdone. Thank you for another fantastic video!
Thank you so much for throwing light on this topic. I have always felt that hyaluronic acid was kind of overrated. When I use it, my skin is okay - but doesn't really feel hydrated. Makes sense now!
So many spelling errors sorry I mean I threw all of my HA products after speaking with Ivan and my skin looked so much better 10 days after. Thanks Ivan.
Hi, I'm reposting this just in case you failed to notice it where I posted it, as part of a conversation with had on the mechanisms of how Adipeau cream actually augments facial fat. Hopefully this time you will see it, and can find the time to answer it. Thank you in advance. The following is my exact original post, my questions and reply : Thanks so much, I was going through some of the studies listed in the Adipeau site, and I think I realize how I may have misunderstood a key element to this whole thing. I think that what you may actually be postulating is that the the linoleic and oleic acids in these natural oils serve as a sort of biochemical stimulant to the DWAT, which prompts the adipocytes to produce more lipids. What I initially thought you were saying was that the exogenous oils themselves somehow infiltrate these fat cells and "fill them up" as it were, with additional fat. Did I get it wrong? Is what you've been saying all this time that these fatty acids act as stimulants, as apposed to what I thought you were saying ? That the oils themselves were contributing fat to the DWAT ? If that's the case, then the whole scenario seems much more sensible, as it would then simply be a biochemical reaction caused by the fatty acids upon the DWAT, as apposed to what I initially thought you were saying, that the adipocytes within the DWAT were somehow being "mechanically" flooded with additional lipids by the exogenous oils that the adipocytes were coming into contact with. Did I initially get it wrong ? Am I understanding it correctly now ? Please let me know. I very much appreciate your time and effort, Thanks
One part is that oleic acid and linoleic acid can trigger ppar gamma in pre adipocytes causing them to become mature adipocytes. But linoleic acid and oleic acid also are taken up by mature adipocytes. And the mature cells get bigger. That’s the problem. When the mature cells get too big, they signal to the pre adipocytes not to convert.
@@aeducator1 Wow, that's amazing, and if proven conclusively true by in vivo studies, this discovery can be said to be quite revolutionary. That adipocytes can take-in topically applied fatty acids and actually make them part of their own lipid content, is from what I know, an unprecedented finding. Well kudos to you ! Hopefully further studies will shed more light on this hypothesis. Thanks again
I am using a toner with 15 pp molecule size hyaluronic acid which they say only sits on top of the skin cause of its size is that fine as long as the molecular size of the HAis high enough so that it does not seep into the skin? I am trying to figure out ways to maximize the adipeau results by also using the tatcha essence before i apply the cream which is supposed to help increase product absorption and i do feel that it helps but i am curious to know what you think about microcurrent. Current caused my facial fat loss but now after doing research I believe 350 uA and up is very bad. Would 50 to 75 uA of microcurrent help wake the cells up before applying the adipeau cream? Nobody talks about the natural levels of current in the face etc so how would they even know what amount of current is sufficient to use from a device? Microcurrent is another topic that is hyped up without any proper research attached to it.
You read my mind! We just recorded an episode on microcurrent. It will publish later this week. You are in the right path for sure. Re the molecular weight of HA, there is NO weight that just sits on top of the skin. It all penetrates. You don’t need to enhance the Adipeau penetration. It goes down the pore on its own thanks to the linoleic acid in safflower seed oil.
@@aeducator1 its so hard to find products without HA added into the ingredients. What can you recommend to use if we can't use anything with HA or retinol? There is a good molecules niacinamide toner i just started using and ofcourse they added a small amount of HA. To clarify no amount of HA or "vegan" HA people use now a days is good for the fat cells? I have been using the tatcha essence (doesnt seem to have HA) that helps the skin penetrate products more and I apply the adipeau on top of it. I feel like it is helping me see results with Adipeau faster. Wish I found this combination out sooner. Excited for the microcurrent video!
Hello, thank you for the wonderful work you're doing! I know this is off-topic, I'm sorry, but I'd be really greatful if I get a reply. I'd like to ask you if the Adipeau cream is effective for people affected by autoimmune diseases like Hashimoto's for example.
I usually buy fresh aloe vera leaf in the store and i use it as my HA substitute. Fresh aloe leaf works amazing. I put it on my face, lips, neck and decolette. And when the alove vera gel dries out i put natural oil ( tamanu, rosehip are my favourite) And then i spray my face with distilled water. This combination gives me the best hydration ever ! 😊
I absolutely agree about all that you said about topical HA. Makes so much sense. But, I genuinely need to know where the studies/research are that indicate skin does NOT lose HA as we age. I have always been told that we lose it. I’m open minded, but I genuinely would like to see the research. Can you post any links to the particular research that you are relying on that caused you to draw the conclusion that skin does not lose HA as we age?
Its an old article by meyer and stern entitled "Age Dependent Changes of Hyaluron in Human Skin" , 1994, Journal of Investigative Dermatology. It's a tiny pathology study but it's the only one I could find. And it's been cited by good publications.
My skin always felt dehydrated after using HA and I was told that HA needs to draws moisture in from wherever it can and if cannot get it from the air it will take it from your own skins moisture.
Thank you so much for this Ivan. Now if we can get our clients to stop using it. I do not retail this in my treatment room, but these skin junkies are addicted to it. Wish there was a way to get clients to only buy what us Estheticians sell. :) Your the Best - we appreciate all appreciate you educating us.
I'm wondering the same about taking it internally. I'm seeing this more in the form of pills and liquids. It sounds like it may be okay but is it beneficial?
How about those hydrogel collagen masks that use low molecular HA? The holes created by HA allow the collagen to penetrate but in this case the skin is actually damaged?
Thank you so much for this. It’s funny, I’ve been phasing out products and HA was one of them just on gut feeling. I did however purchase a Vit C serum that has it and it’s been better for my skin than the previous Vit C I was using. It was breaking me out in red dots. If anyone has a suggestion for Vit C without HA please mention. I remember hearing you say we should be using that.
Hi , what should I use right before and after home micro needling ? Because they all seem to recommend some type of hyaluronic acid after and during the rolling ….please !!!
I love this conversation and appreciate your replies to some of the comments! Please keep sharing your findings with us! I love the Adipeau product I feel like even though I haven’t had a lot of fat loss yet it makes my skin look healthier and will continue to use it. I occasionally dermaplane my face to get rid of peach fuzz- will this affect the absorption of the Adipeau without the hair coming out of the follicles?
This is great to know, thank you! Now I know why my skin is all of a sudden dry. I’d like to hear what you think is the best skin care regimen then :) I’m down to my Adipeau and my own tallow lotion (seriously best results!)
Sorry, I do have another question! I’ve been wondering about the use of preservatives in skincare products (which I totally get are necessary so they have longer shelf lives) and how that negatively impacts/disrupts our skin microbiome. I’ve seen some research on this and am wondering if you can speak to that? How on earth do we avoid disrupting our microbiome while using skincare products w that necessarily have to have some kind of preservative?
That's a great question. And one that I don't know a lot about. I think that most preservatives are not killing bacteria but rather limiting their potential to grow exponentially. The way the microbiological testing is done is that they formulas are spiked with known quantities of bacteria and then they measure how much those bacteria can multiply. If the amount of multiplication is low enough, the product passes the micro test. So this implies that the preservatives used in skincare won't necessary kill of the good bacteria on the skin. But your question is a good one and further supports the less is more approach to skincare.
@@kristens698 great question. I don’t think so. The wounds created by micro needling should be so minimal that they would need no assistance in resolving. It’s only in the case of large open wounds where the skin needs help to tilt the balance
Fascinating! I never understood until now why my skin got so dry and irritated on HA when everyone says it is so good. For moisturizers lately I've been using Adipeau, Purity Woods Anti Aging Dream Cream, Minimalist 3% Ceramides Moisturizer, and Innbeauty C and Peptides Moisturizer. None of those have HA as far as I can tell from the ingredient list. This is really annoying, as I read through ingredient lists as none of the skincare lines seem to be HA free, but some do have individual products that are free of it. But honestly, Adipeau is the nicest moisturizer I have tried so far. I rotate the others as a way to get actives in a form that won't irritate me.
@@SleeplessinOCIt’s a great moisturizer so far. A lot of moisturizers just seem to sit on top of the skin for me. This one actually seems to hydrate and is soothing. I also always try to apply moisturizers when the skin is slightly damp.
I just bought some HA to try for the first time. I have super dry skin so moisture is vital for me. I literally see my skin crack if I don't keep applying moisturizer. I've never met anyone like me but I'm sure there are a few. I didn't hear anyone else suggesting NOT to use it but I'm going to do more research. That's if there's even anything out there to read about the negative effects!
Also now I wonder if HA vaginal suppositories are not good either. I stopped using it on my face since I started with Adipeau almost a year ago but still take the pill form 300mg and was using the vaginal until I got the Estrodial ….. I’ve read we loose HA from within the body I believe I just heard you say we don’t. Thoughts?
First of all,I love my adipeau! And the body cream you sent, I wish I had more! Thank you for this. I don’t really use hyaluronic acid but good to know!!
I listen to You and absorb knowledge as much as I understand, but I don't know English well enough to understand it easily. Do you have a way to do it? Just please don't tell me that I have to learn - I know it :) Thank you for Your work! Regards from Poland!
Wow. That is so great. You can take the transcripts of the episodes and translate them into Polish with google translate. It may give you some more information than you are getting right now.
I used H acid for few days which didn’t work for me then used another brand the same story so never used it again. I listen to my body not the influencers , but I’m glad to hear science backed discussion any time 🙏🏻
😳 I just checked Hya acid is literally in ALL my skin products, minus my cleansers & single ingredient face oils. If I decide to phase HA out (likely!), where do I turn!?
@@aeducator1 😉 I LOVE the Adipeau Active Face Cream for night, but it’s a bit heavy during the day for me, especially during the insanely hot summer months. Any plans on making something for day/with an SPF? All of my face SPF creams are loaded with HA as well. 😢
@@aeducator1Yippee! Cannot wait to check it out. Thanks for all you do. 👏I've done medical research over the years, so I fully respect the time commitment; the study rabbit holes are endless...
Moisture should flow naturally from within the skin, and not from some kind of external "wetting agent" like hyaluronic acid or moisturizing creams. If the surface of your skin is continuously dry you're either on some type of necessary prescription medicine like a retinoid or benzoil peroxide, or you are DOING SOMETHING WRONG. You must be over cleansing or actively doing something else that is disturbing your skins natural, moisture preserving protective mantle. Healthy skin MOISTURIZES ITSELF, with zero need for exogenous moisturizers. This old-school idea of keeping the skin continuously "moist" with creams and potions is totally unnatural, and in time, quite detrimental to the skin. Wrinkles aren't caused because of "moisture loss" or "dehydration", wrinkles come from the breakdown of the supporting structures within the skin, and that is caused by sun exposure and plain ol' intrinsic aging. So stop drowning the skin in humectants like hyaluronic acid and moisturizers. Gentle cleansing, an antioxidant serum, and sun protection are basically all most people need. As skin gets older the judicious use of hydroxy acids, peptides, and retinoids may be useful additions.
@@aeducator1 Hi, it seems to me that you need to further elucidate how it is exactly that topically applied fats like safflower or cottonseed oil can travel down into the hair follicles, actually enter into the DWAT structures, and by exogenous addition of fat, augment the DWAT's fat content. In other words, how it is that these externally applied oils manage to become part of the fatty content of DWAT itself ?? This does not appear possible to me, please clarify.
@@moonhaze8332 there are two questions here. First, do topically applied oils reach the dwat? And second what happens if/when they come into contact with pre/adipocytes and mature adipocytes. Both question are answered by peer reviewed publications. You can find the citations on the science page of the adipeau website. We’ve also done our own research with the Karolinska institute. The publication is being prepared. Thank you for your inquiry!
@@aeducator1 I could readily accept that fatty acids could possibly travel down the hair follicles, and that the possibility exists that they might reach the DWAT. So we could consider that part of the equation "a piece" of the question, but that's not truly the crux of it. The real, and more pertinent question is if in fact these topically applied fats actually become incorporated into the already existing fat composition of DWAT itself, and do these exogenous fatty acids actually "fatten up", via "osmosis" or whatever other mechanism it is that you propose, the existing adipocytes within the DWAT. If this is even at all possible. That is the actual question. Please be so kind as to list for me the exact studies you mention here. I'd rather you point to the one or two most pertinent ones, so as to not waste time reading the wrong ones. Thanks very much
@@moonhaze8332 I really appreciate your interest. Here is the publication of how kaempferia parvifloa extract (KPE) promotes regeneration of fat cells. It increases the number of PPARgamma receptors. We don't know how it does that. The PPAR gamma receptor is the "master regulator" of adipogenesis. Horikawa T, Shimada T, Okabe Y, Kinoshita K, Koyama K, Miyamoto K, Ichinose K, Takahashi K, Aburada M. Polymethoxyflavonoids from Kaempferia parviflora induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. Biol Pharm Bull. 2012;35(5):686-92. doi: 10.1248/bpb.35.686. PMID: 22687402. Linoleic acid and oleic acid can signal through PPAR gamma to stimulate adipogenesis. Here is the relevant publication. Kokta TA, Strat AL, Papasani MR, Szasz JI, Dodson MV, Hill RA. Regulation of lipid accumulation in 3T3-L1 cells: insulin-independent and combined effects of fatty acids and insulin. Animal. 2008 Jan;2(1):92-9. doi: 10.1017/S1751731107000936. PMID: 22444967. We have now had an independent top-tier academic institution conduct the experiment with safflower seed oil and KPE.
Oh! That confirms the gut feeling i had for some time 😮. Got suspicious that it was more drying than helping my skin also a general not tolerating it well and more inflammation.
So the capsule form does not have the same negative effects on the skin barrier. I think - but I need to check - that the oral ha is broken down into fragments that are not inflammatory. The effects on the skin are positive on first glance but I have to take a deeper look at how the studies were done
Oral supplementation looks to be OK but I have to do a deep dive on how the studies were done. The devil is always in the details. But on first glance, oral HA is ok.
Sadly hyaluronic acid is in almost every thing skin care, even in physical sunscreens! Now isn’t that counterintuitive since the product is supposed to sit on the top of the skin & not penetrate.
The idea that hyaluronic acid sits on top of the skin is clearly false but has been perpetuated by experts who only consider the molecular weight and not the data. Based on molecular weight, even the lowest weight hyaluronic acid should not penetrate. The fact that it does- to 85 percent- should scream “something is different about this molecule!
I have to say I disagree with this. I have very dry sensitive skin and now that I’m older it’s gotten worse. I use a vitamin c serum that has HA in it and it’s done wonders for me. My skin looks youthful, hydrated, smooth and glowing.
The woman appears to have hyaluronic acid injections on her lips (or a strange make up on the lips? Or both). I thought this video was about this type of hyaluronic acid. Injections aren't good for the skin either, it seems.
just jotted these thought down as I watched, so not meant to be completely accurate or grammatically correct. But I don’t want to spend any more time on this video that feels scammy🥰 “Pokes holes” “Throws monkey wrenches “ Disregulates lipid structure?? “We like to be fact based” where are the published studies about disregulated lipid structure from HA? Can’t just say and not cite. “Water doesn’t belong in the skin” so hydrating skin externally in any capacity is wrong? That ha is bypassing top layers of skin and leaving shriveled corneocytes up top doesn’t make sense. If it s holding water, it’s holding water and surrounding tissue will have it there if there is apppropriate lipid on top layer which would be in a moisturizer. Fear mongering things are getting into the blood stream Sneaking/hacking? Products that are formulated to get where they need to go is the draw of effective formulations. “There’s been no study about ha being sensitizing.” “They need to do that by putting irritants on the skin (“lavender oil, fragrance) other than ha to show that ha is sensitizing”. You don’t need to add a known irritant to the skin to prove skin is sensitized. If ha does that, skin will show it. Brands that are quality will let you know what molecular structure of HA you are getting in products🙄 you are using a blanket statement saying no brands do. “Ha cause inflammation””it’s hits the tolls like receptors” Again, not language that build confidence. What receptors? What specific receptors are they hitting, what studies were done? To recap it’s poking holes in the skin (the actress/skin enthusiast understanding of all that was said) then bad “stuff” gets in, water which is good gets out (although earlier in the video water doesn’t belong in the skin) Now on a wound with inflammation, the HA is anti inflammatory? Just because the circumstances are different? The ingredient now works completely good, doing all the things it is said to do? Holding water to the skin? You shouldn’t put sensitizing ingredients on a wound. Since there’s no studies that it is, probably shouldn’t have that as a segment in the video. “It’s not that dermatologists are stupid”(implying they are) They just don’t have time (implying they don’t study)
I was wondering about some of these statements as well and would look forward to their response. I agree, if claims are made then citations should be provided and links to the studies included.
Thanks for such an engaging comment. I've added all the citations so you can see that this episode is entirely peer-review fact based except where noted. To address a couple of your very reasonable points of criticism. Point 1) Why is using HA to get peptides into the skin "sneaking?" Because the manufacturers don't tell you that they are using the hyaluronic acid as a penetrant. I know that's a subtlety. But it's important. Most people don't know that hyaluronic acid is a penetrant. And most people don't know that hyaluronic acid compromises the skin barrier. They just assume that the HA in the formulation is for "moisturizing." So by being silent on these facts and the real reason why they've included HA in the formula, the manufacturers are being sneaky. Not horrible, just sneaky. Point 2) Ingredients can be sensitizing on their own or they can enable or exacerbate sensitivity. HA has the latter two effects. We did not get into it in depth in the video but I've put a citation to the publication that shows how HA is pro-inflammatory in the context of skin sensitization. By the way, toll-like receptors are the receptors hit by HA, specifically TLR-2. Toll-like is the scientific name. I know that sounds weird. Point 3) Would be interested in knowing which brands tell you the molecular weight of the hyaluronic acid they include in the formula. The molecular weight of what they start with in the manufacturing process is very likely not what you get when you buy the product, and certainly not what you get when the HA is processed by the skin. The bigger point here is that the molecular weight of HA is only relatively important. Not absolute. ALL HA PENETRATES THE SKIN.
Apart from one viewer who had nothing positive to say about this episode, we have only heard positive comments. While this is nice, it's also a bit surprising. HA is one of the most frequently used cosmetic ingredients and our recommendation is to NOT use it if you have intact skin. Where are all of the HA supporters?
I am so happy that you have just validated how I have personally found HA to be not tolerated by my skin & could not understand the hype & results that everyone is talking about. I always found it dehydrating and sensitising to my skin. Luckily I understand my skin quite well & can see what it does and doesn't like & act accordingly. ...despite various hypes.
My only frustration is, that it is genuinely hard to find skincare without HA jammed into it.
Or my other nemesis squalane, which also is not tolerated by my skin as it always makes me break out. Actually, I would greatly appreciate a deep dive into squalane.
I just randomly came across this video & you certainly got my attention!
Thank you for making me feel not crazy ❤
Yes, you are not crazy! The science could not never any more straight forward. Ty for joining our little community.
My skin reacts the same way to HA but interestingly, the same with squalene. I thought I was an anomaly with the “bio-identical”
squalane; I wonder what the connect could be. 🤔
I have also specifically had reactions to HA and squalane! (And it’s so hard to find products!) And I know it was HA and squalane specifically because I used pure HA with just a natural, gentle preservative and I had a reaction to it and then much later used pure squalane and got a horrible rash. I wonder if being sensitive to both is related.
@@JamiLaundryme too with both HA and squalane! I thought it was just me but I see two other people on here saying they had reactions to those specific ingredients as well
@@surrendertoflow78 HA will create sensitivity by making the skin susceptible to antigens. It could be something in the environment, not in your skincare regimen. Then the small fragments of HA feed the sensitivity reaction.
I just saw a video by Dr Idriss from 2 years ago about hyaluronic acid. She confirms EVERYTHING you have reported in this video! Thank you!
Mary Schook was one of the first to bring this up and she was practically villainized by the industry. HA absolutely inflames/irritates my skin and completely dries it out on another level, especially lower molecular weights. I’ve even purchased $100+ bottles and it’s the same inflammation/dryness every time. I don’t understand how this is a holy grail ingredient for so many and it’s literally in EVERYTHING. When I found Mary a few years ago, I dropped the HA and my skin did a 180. Thank you for both for creating additional awareness!
It was Mary who first clued me in. Idiot that I am, it took me a year to remove HA from my product. I am sorry to hear that Mary got sh$t for her views. It’s important to have respectful debate.
Can you mention some of the true and tried products you love ? I too want to find effective products for my aging dry skin but it seems everything has them 😒😒
I used this and simply helped my acne scars.
Thank you so much. I had a client complain that she felt her skin being drier after using HA, and now I understand! I love all this clinical information so I can do my best for my clients. I've looked through all my products and most of them have it as an ingredient.
Dr Shereen Idriss had a video on HA channeling the same sentiments. I always wondered why my skin looked more dry after putting my HA sunscreen when I reached the office and the problem immediately disappeared once I ditched all HA containing products. I now only use high molecular HA serum when I microneedle every couple of months and that's it.
Such great information! And I now feel validated. I had the same experience where my skin would become more irritated and drier after using hyaluronic acid in any form. Thanks for getting this information out there. More people need to be aware of the negative side effects.
So glad this helped. Thank you for your support.
Thanks so much for this info because I always thought my skin was dryer and stopped using it but now it's in everything.
I tree all of my hypersonic acid products 3 weeks ago and my skin already is thanking me .
Thanks Ivan for bringing this info to us.
Your skin knows. Sometimes the mind gets in the way. Thank you for your trust.
Thank you for bringing awareness to one of the most ubiquitous topics in the skin care industry. I appreciate the research and science that went into presenting the information and video. Thank you.
what about microneedling with special products like from Korea? Or the Hyaron, that is very famous for being used for mesotherapy etc
Thank you Ivan! this also plays greatly into the whole filler debacle. All that hyaluronic acid that is injected into people - causing all types of inflammation and therefore aging in people.
Blessings
Yes, the fragments of HA filler may become inflammatory as the parent molecules degrade!
Thank you for this information. I noticed that HA left my skin dry feeling after it dried as opposed to the glycerine and water mix that I usually use. I've heard similar things about glycerine but my skin always feels moist and looks plump after using it. I live in a desert btw. Mix it with rosewater in the right ratio and there won't be any tackiness.
I believe in your research, Ivan! But, I really wonder how those people who use retin A tighten their face!
I have witnessed those.
I stopped it coz it dried my skin badly.
Thanks Abeer. The tightening with Retin-A is temporary and unnatural.
Good episode. Easy to follow the format
Thanks Amar. We are evolving
I’ve had reactions to HA before and now I’m realizing it might have been due to it sensitizing my skin over time. Thank you so much for this. I know Adipeau doesn’t have HA in it (which I am thrilled about). But that is something I don’t use as a moisturizer on my whole face (it works wonderfully for increasing volume, just don’t use it as a general everyday moisturizer). It’s SO hard to find anything else without HA for mature skin. I also had a reaction to pure sugar cane squalane as did another commenter. I wonder if there’s any connection to having reactions to both HA and squalane? It’s also getting very difficult to find moisturizers without squalane, which seems to be the next big hype.
1) Does anyone have any HA-free (and squalane-free) recommendations for daily light moisturizer?
2) Are there any other ingredients that help peptides get into the skin that aren’t damaging or should we be ignoring the peptide hype as well?
Thank you!
Also curious about (1). If a product has propylene glycol listed in the top 5 ingredients, then you should watch out for that. But HA is really a penetrant of choice because most people -- including the dermatologist referred to -- don't know that it's a penetrant and assume that it's doing something positive.
I LOVE using grassfed beef tallow for my face as a moisturizer. Ill never go back to anything else.
@@bayleymacintosh5622isn’t that a cooking ingredient ?
How is it with hyaluronic acid filler? It would be very interesting to know, I still find it works very well if it's not overdone.
Thank you for another fantastic video!
Yikes! Good question.
Thank you so much for throwing light on this topic. I have always felt that hyaluronic acid was kind of overrated. When I use it, my skin is okay - but doesn't really feel hydrated. Makes sense now!
So many spelling errors sorry I mean I threw all of my HA products after speaking with Ivan and my skin looked so much better 10 days after.
Thanks Ivan.
Hi, I'm reposting this just in case you failed to notice it where I posted it, as part of a conversation with had on the mechanisms of how Adipeau cream actually augments facial fat. Hopefully this time you will see it, and can find the time to answer it. Thank you in advance.
The following is my exact original post, my questions and reply :
Thanks so much, I was going through some of the studies listed in the Adipeau site, and I think I realize how I may have misunderstood a key element to this whole thing.
I think that what you may actually be postulating is that the the linoleic and oleic acids in these natural oils serve as a sort of biochemical stimulant to the DWAT, which prompts the adipocytes to produce more lipids.
What I initially thought you were saying was that the exogenous oils themselves somehow infiltrate these fat cells and "fill them up" as it were, with additional fat.
Did I get it wrong? Is what you've been saying all this time that these fatty acids act as stimulants, as apposed to what I thought you were saying ? That the oils themselves were contributing fat to the DWAT ?
If that's the case, then the whole scenario seems much more sensible, as it would then simply be a biochemical reaction caused by the fatty acids upon the DWAT, as apposed to what I initially thought you were saying, that the adipocytes within the DWAT were somehow being "mechanically" flooded with additional lipids by the exogenous oils that the adipocytes were coming into contact with.
Did I initially get it wrong ?
Am I understanding it correctly now ?
Please let me know.
I very much appreciate your time and effort, Thanks
One part is that oleic acid and linoleic acid can trigger ppar gamma in pre adipocytes causing them to become mature adipocytes. But linoleic acid and oleic acid also are taken up by mature adipocytes. And the mature cells get bigger. That’s the problem. When the mature cells get too big, they signal to the pre adipocytes not to convert.
@@aeducator1
Wow, that's amazing, and if proven conclusively true by in vivo studies, this discovery can be said to be quite revolutionary. That adipocytes can take-in topically applied fatty acids and actually make them part of their own lipid content, is from what I know, an unprecedented finding.
Well kudos to you !
Hopefully further studies will shed more light on this hypothesis. Thanks again
I am using a toner with 15 pp molecule size hyaluronic acid which they say only sits on top of the skin cause of its size is that fine as long as the molecular size of the HAis high enough so that it does not seep into the skin? I am trying to figure out ways to maximize the adipeau results by also using the tatcha essence before i apply the cream which is supposed to help increase product absorption and i do feel that it helps but i am curious to know what you think about microcurrent. Current caused my facial fat loss but now after doing research I believe 350 uA and up is very bad. Would 50 to 75 uA of microcurrent help wake the cells up before applying the adipeau cream? Nobody talks about the natural levels of current in the face etc so how would they even know what amount of current is sufficient to use from a device? Microcurrent is another topic that is hyped up without any proper research attached to it.
You read my mind! We just recorded an episode on microcurrent. It will publish later this week. You are in the right path for sure. Re the molecular weight of HA, there is NO weight that just sits on top of the skin. It all penetrates. You don’t need to enhance the Adipeau penetration. It goes down the pore on its own thanks to the linoleic acid in safflower seed oil.
@@aeducator1 its so hard to find products without HA added into the ingredients. What can you recommend to use if we can't use anything with HA or retinol? There is a good molecules niacinamide toner i just started using and ofcourse they added a small amount of HA. To clarify no amount of HA or "vegan" HA people use now a days is good for the fat cells? I have been using the tatcha essence (doesnt seem to have HA) that helps the skin penetrate products more and I apply the adipeau on top of it. I feel like it is helping me see results with Adipeau faster. Wish I found this combination out sooner. Excited for the microcurrent video!
how about consuming it...plz enlighten us about that
Hello, thank you for the wonderful work you're doing! I know this is off-topic, I'm sorry, but I'd be really greatful if I get a reply. I'd like to ask you if the Adipeau cream is effective for people affected by autoimmune diseases like Hashimoto's for example.
I usually buy fresh aloe vera leaf in the store and i use it as my HA substitute. Fresh aloe leaf works amazing. I put it on my face, lips, neck and decolette. And when the alove vera gel dries out i put natural oil ( tamanu, rosehip are my favourite) And then i spray my face with distilled water. This combination gives me the best hydration ever ! 😊
I absolutely agree about all that you said about topical HA. Makes so much sense. But, I genuinely need to know where the studies/research are that indicate skin does NOT lose HA as we age. I have always been told that we lose it. I’m open minded, but I genuinely would like to see the research. Can you post any links to the particular research that you are relying on that caused you to draw the conclusion that skin does not lose HA as we age?
Its an old article by meyer and stern entitled "Age Dependent Changes of Hyaluron in Human Skin" , 1994, Journal of Investigative Dermatology. It's a tiny pathology study but it's the only one I could find. And it's been cited by good publications.
My skin always felt dehydrated after using HA and I was told that HA needs to draws moisture in from wherever it can and if cannot get it from the air it will take it from your own skins moisture.
Exactly! Thanks for sharing your experience.
Is this valid as well for HA fillers or medical aesthethical treatments ?
it has temporary good effects, very temporary, long term bad. thank you for sharing.
Thank you for telling the truth! HA has always made my skin worse.
Thank you so much for this Ivan. Now if we can get our clients to stop using it. I do not retail this in my treatment room, but these skin junkies are addicted to it. Wish there was a way to get clients to only buy what us Estheticians sell. :) Your the Best - we appreciate all appreciate you educating us.
Wow! I've been so dedicated to apply HA in my beauty routine. No More! Thank you.
What about taking HA? Is it any good?
It’s much better than putting it in the skin.
I'm wondering the same about taking it internally. I'm seeing this more in the form of pills and liquids. It sounds like it may be okay but is it beneficial?
Gracias Ivan y Paice por tan valiosa información ❤
Thanks Martha!
Is Glycerin safe for the skin as it’s a potent humectant as well?
Glycerin is much safer because it does not poke holes in the skin. It’s also a less potent humectant than HA.
How about those hydrogel collagen masks that use low molecular HA? The holes created by HA allow the collagen to penetrate but in this case the skin is actually damaged?
Thank you so much for this. It’s funny, I’ve been phasing out products and HA was one of them just on gut feeling. I did however purchase a Vit C serum that has it and it’s been better for my skin than the previous Vit C I was using. It was breaking me out in red dots. If anyone has a suggestion for Vit C without HA please mention. I remember hearing you say we should be using that.
Your gut knows the truth. Often your mind gets in the way.
You could try Prequel Lucent-C , very straightforward composition and affordable.
@@xtian384 thanks!
@@xtian384 That’s actually the one that made me reactive 🥹
@@xtian384 That’s the one that caused the irritation. Wanted to love it!
Hi , what should I use right before and after home micro needling ? Because they all seem to recommend some type of hyaluronic acid after and during the rolling ….please !!!
Great video. Dr Ivan, is it possible to reverse the effects of hyaluronic acid akincare ? I'm started using Adipeau for a year now
MR. Ivan. I am just a regular person. Yes, the skin will recover in just a few weeks after stopping hyaluronic acid.
I love this conversation and appreciate your replies to some of the comments! Please keep sharing your findings with us! I love the Adipeau product I feel like even though I haven’t had a lot of fat loss yet it makes my skin look healthier and will continue to use it. I occasionally dermaplane my face to get rid of peach fuzz- will this affect the absorption of the Adipeau without the hair coming out of the follicles?
Does The ordinary use HA in their serum withe copper peptides ? I do not read HA in the list of ingredients
Yes, they do use hyaluronic acid.
This is great to know, thank you! Now I know why my skin is all of a sudden dry. I’d like to hear what you think is the best skin care regimen then :) I’m down to my Adipeau and my own tallow lotion (seriously best results!)
What would you recommend for microneedling? What about Mucin?
Sorry, I do have another question! I’ve been wondering about the use of preservatives in skincare products (which I totally get are necessary so they have longer shelf lives) and how that negatively impacts/disrupts our skin microbiome. I’ve seen some research on this and am wondering if you can speak to that? How on earth do we avoid disrupting our microbiome while using skincare products w that necessarily have to have some kind of preservative?
That's a great question. And one that I don't know a lot about. I think that most preservatives are not killing bacteria but rather limiting their potential to grow exponentially. The way the microbiological testing is done is that they formulas are spiked with known quantities of bacteria and then they measure how much those bacteria can multiply. If the amount of multiplication is low enough, the product passes the micro test. So this implies that the preservatives used in skincare won't necessary kill of the good bacteria on the skin. But your question is a good one and further supports the less is more approach to skincare.
@@aeducator1Thank you so much for taking that question seriously and for your thoughtful response! ❤
If HA works as an anti-inflammatory on wounded skin, would high molecular weight HA be an appropriate choice for microneedling?
@@kristens698 great question. I don’t think so. The wounds created by micro needling should be so minimal that they would need no assistance in resolving. It’s only in the case of large open wounds where the skin needs help to tilt the balance
Fascinating! I never understood until now why my skin got so dry and irritated on HA when everyone says it is so good. For moisturizers lately I've been using Adipeau, Purity Woods Anti Aging Dream Cream, Minimalist 3% Ceramides Moisturizer, and Innbeauty C and Peptides Moisturizer. None of those have HA as far as I can tell from the ingredient list. This is really annoying, as I read through ingredient lists as none of the skincare lines seem to be HA free, but some do have individual products that are free of it. But honestly, Adipeau is the nicest moisturizer I have tried so far. I rotate the others as a way to get actives in a form that won't irritate me.
How do you like the Purity woods dream cream ? I ordered it after seeing your comment and I’m waiting for it to arrive .
@@SleeplessinOCIt’s a great moisturizer so far. A lot of moisturizers just seem to sit on top of the skin for me. This one actually seems to hydrate and is soothing. I also always try to apply moisturizers when the skin is slightly damp.
I just bought some HA to try for the first time. I have super dry skin so moisture is vital for me. I literally see my skin crack if I don't keep applying moisturizer. I've never met anyone like me but I'm sure there are a few. I didn't hear anyone else suggesting NOT to use it but I'm going to do more research. That's if there's even anything out there to read about the negative effects!
Also now I wonder if HA vaginal suppositories are not good either. I stopped using it on my face since I started with Adipeau almost a year ago but still take the pill form 300mg and was using the vaginal until I got the Estrodial ….. I’ve read we loose HA from within the body I believe I just heard you say we don’t. Thoughts?
First of all,I love my adipeau! And the body cream you sent, I wish I had more! Thank you for this. I don’t really use hyaluronic acid but good to know!!
I listen to You and absorb knowledge as much as I understand, but I don't know English well enough to understand it easily. Do you have a way to do it?
Just please don't tell me that I have to learn - I know it :)
Thank you for Your work! Regards from Poland!
Wow. That is so great. You can take the transcripts of the episodes and translate them into Polish with google translate. It may give you some more information than you are getting right now.
yes! great chat. is sodium hyaluronic also an ingredient to avoid?
yes, sodium hyaluronate is just a different chemical form (e.g., salt) of hyaluronic acd.
I used H acid for few days which didn’t work for me then used another brand the same story so never used it again. I listen to my body not the influencers , but I’m glad to hear science backed discussion any time 🙏🏻
Are you saying Tretinoin cream is bad for the skin as well? If so, could you point me to the research supporting this?
So would microneedling be included in "open wound" good use?
😳 I just checked Hya acid is literally in ALL my skin products, minus my cleansers & single ingredient face oils. If I decide to phase HA out (likely!), where do I turn!?
I’ve got a solution, but I can’t mention it here. :)
@@aeducator1 😉 I LOVE the Adipeau Active Face Cream for night, but it’s a bit heavy during the day for me, especially during the insanely hot summer months. Any plans on making something for day/with an SPF? All of my face SPF creams are loaded with HA as well. 😢
@@wendylpa we are introducing a 2nd product next week. It’s lighter.
@@aeducator1Yippee! Cannot wait to check it out. Thanks for all you do. 👏I've done medical research over the years, so I fully respect the time commitment; the study rabbit holes are endless...
p.s. the planet also needs an Adipeau Eye Cream!
Moisture should flow naturally from within the skin, and not from some kind of external "wetting agent" like hyaluronic acid or moisturizing creams.
If the surface of your skin is continuously dry you're either on some type of necessary prescription medicine like a retinoid or benzoil peroxide, or you are DOING SOMETHING WRONG. You must be over cleansing or actively doing something else that is disturbing your skins natural, moisture preserving protective mantle.
Healthy skin MOISTURIZES ITSELF, with zero need for exogenous moisturizers. This old-school idea of keeping the skin continuously "moist" with creams and potions is totally unnatural, and in time, quite detrimental to the skin.
Wrinkles aren't caused because of "moisture loss" or "dehydration", wrinkles come from the breakdown of the supporting structures within the skin, and that is caused by sun exposure and plain ol' intrinsic aging.
So stop drowning the skin in humectants like hyaluronic acid and moisturizers. Gentle cleansing, an antioxidant serum, and sun protection are basically all most people need. As skin gets older the judicious use of hydroxy acids, peptides, and retinoids may be useful additions.
Thank you for engaging. Completely agree with your sentiment about the skin taking care of itself.
@@aeducator1
Hi, it seems to me that you need to further elucidate how it is exactly that topically applied fats like safflower or cottonseed oil can travel down into the hair follicles, actually enter into the DWAT structures, and by exogenous addition of fat, augment the DWAT's fat content.
In other words, how it is that these externally applied oils manage to become part of the fatty content of DWAT itself ??
This does not appear possible to me, please clarify.
@@moonhaze8332 there are two questions here. First, do topically applied oils reach the dwat? And second what happens if/when they come into contact with pre/adipocytes and mature adipocytes. Both question are answered by peer reviewed publications. You can find the citations on the science page of the adipeau website. We’ve also done our own research with the Karolinska institute. The publication is being prepared. Thank you for your inquiry!
@@aeducator1
I could readily accept that fatty acids could possibly travel down the hair follicles, and that the possibility exists that they might reach the DWAT. So we could consider that part of the equation "a piece" of the question, but that's not truly the crux of it.
The real, and more pertinent question is if in fact these topically applied fats actually become incorporated into the already existing fat composition of DWAT itself, and do these exogenous fatty acids actually "fatten up", via "osmosis" or whatever other mechanism it is that you propose, the existing adipocytes within the DWAT. If this is even at all possible. That is the actual question.
Please be so kind as to list for me the exact studies you mention here.
I'd rather you point to the one or two most pertinent ones, so as to not waste time reading the wrong ones. Thanks very much
@@moonhaze8332 I really appreciate your interest. Here is the publication of how kaempferia parvifloa extract (KPE) promotes regeneration of fat cells. It increases the number of PPARgamma receptors. We don't know how it does that. The PPAR gamma receptor is the "master regulator" of adipogenesis.
Horikawa T, Shimada T, Okabe Y, Kinoshita K, Koyama K, Miyamoto K, Ichinose K, Takahashi K, Aburada M. Polymethoxyflavonoids from Kaempferia parviflora induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. Biol Pharm Bull. 2012;35(5):686-92. doi: 10.1248/bpb.35.686. PMID: 22687402.
Linoleic acid and oleic acid can signal through PPAR gamma to stimulate adipogenesis. Here is the relevant publication.
Kokta TA, Strat AL, Papasani MR, Szasz JI, Dodson MV, Hill RA. Regulation of lipid accumulation in 3T3-L1 cells: insulin-independent and combined effects of fatty acids and insulin. Animal. 2008 Jan;2(1):92-9. doi: 10.1017/S1751731107000936. PMID: 22444967.
We have now had an independent top-tier academic institution conduct the experiment with safflower seed oil and KPE.
And it would be great to find products targeted to getting rid of melasma and dark spots without HA …
Oh! That confirms the gut feeling i had for some time 😮. Got suspicious that it was more drying than helping my skin also a general not tolerating it well and more inflammation.
I am confused. So, what is truthfully helpful fir the skin??
for, that is!
What about profhilo hyaluronic acid injections ???
Where can i buy your moisturizer thanks from dallas texas:loren
What about HA in capsule form? Does it have negative effects too?
So the capsule form does not have the same negative effects on the skin barrier. I think - but I need to check - that the oral ha is broken down into fragments that are not inflammatory. The effects on the skin are positive on first glance but I have to take a deeper look at how the studies were done
Súper interesante! Gracias por esta información!!! Yo uso adipeau y es también un increíble humectante! ❤❤❤❤
I hope the future of skincare isn't saturated with HA as much as it is now
What about oral supplentation of hyaluronic acid?
Oral supplementation looks to be OK but I have to do a deep dive on how the studies were done. The devil is always in the details. But on first glance, oral HA is ok.
Sad thing is there are a lot of products that would be wonderful if they left out hyaluronic acid
They either don’t know or need the penetration enhancement.
Very interesting Ivan 😊
What about in pill form?
Sadly hyaluronic acid is in almost every thing skin care, even in physical sunscreens! Now isn’t that counterintuitive since the product is supposed to sit on the top of the skin & not penetrate.
The idea that hyaluronic acid sits on top of the skin is clearly false but has been perpetuated by experts who only consider the molecular weight and not the data. Based on molecular weight, even the lowest weight hyaluronic acid should not penetrate. The fact that it does- to 85 percent- should scream “something is different about this molecule!
I have to say I disagree with this. I have very dry sensitive skin and now that I’m older it’s gotten worse. I use a vitamin c serum that has HA in it and it’s done wonders for me. My skin looks youthful, hydrated, smooth and glowing.
Let’s leave the hair alone while doing interviews. This interview made me uncomfortable.
How about Beta Glucan?
My skin won’t tolerate any actives. Nada.
And how about Sodium Hyaluronate?
It’s the same thing. Just a different chemical form
The woman appears to have hyaluronic acid injections on her lips (or a strange make up on the lips? Or both). I thought this video was about this type of hyaluronic acid. Injections aren't good for the skin either, it seems.
These news are old. No need to demonize HA. Size of molecules does matter. High volume molecules are great and it is soothing and healing the skin
Isn’t Paige great?
And how about taking this as a supplement with pills? 😅
is Retinol legit?
My skin do not like HA based products.
And they are putting it literally everywhere in cosmetics.
It’s amazing, either they don’t know or they don’t care
@@aeducator1 I hope that this information will spread.
Yo digo no, porq he podido notar q algunas personas q lo utilizan muchas veces ,su rostro se va empeorando ,personalmente no me gusta
just jotted these thought down as I watched, so not meant to be completely accurate or grammatically correct. But I don’t want to spend any more time on this video that feels scammy🥰
“Pokes holes”
“Throws monkey wrenches “
Disregulates lipid structure??
“We like to be fact based” where are the published studies about disregulated lipid structure from HA? Can’t just say and not cite.
“Water doesn’t belong in the skin” so hydrating skin externally in any capacity is wrong?
That ha is bypassing top layers of skin and leaving shriveled corneocytes up top doesn’t make sense. If it s holding water, it’s holding water and surrounding tissue will have it there if there is apppropriate lipid on top layer which would be in a moisturizer.
Fear mongering things are getting into the blood stream
Sneaking/hacking? Products that are formulated to get where they need to go is the draw of effective formulations.
“There’s been no study about ha being sensitizing.” “They need to do that by putting irritants on the skin (“lavender oil, fragrance) other than ha to show that ha is sensitizing”. You don’t need to add a known irritant to the skin to prove skin is sensitized. If ha does that, skin will show it.
Brands that are quality will let you know what molecular structure of HA you are getting in products🙄 you are using a blanket statement saying no brands do.
“Ha cause inflammation””it’s hits the tolls like receptors” Again, not language that build confidence. What receptors? What specific receptors are they hitting, what studies were done?
To recap it’s poking holes in the skin (the actress/skin enthusiast understanding of all that was said) then bad “stuff” gets in, water which is good gets out (although earlier in the video water doesn’t belong in the skin)
Now on a wound with inflammation, the HA is anti inflammatory? Just because the circumstances are different? The ingredient now works completely good, doing all the things it is said to do? Holding water to the skin? You shouldn’t put sensitizing ingredients on a wound. Since there’s no studies that it is, probably shouldn’t have that as a segment in the video.
“It’s not that dermatologists are stupid”(implying they are) They just don’t have time (implying they don’t study)
I was wondering about some of these statements as well and would look forward to their response.
I agree, if claims are made then citations should be provided and links to the studies included.
I thought HA went out of favor with dermatologists a couple years ago. He's late to the party. Marketing to the masses is a different topic.
Thanks for such an engaging comment. I've added all the citations so you can see that this episode is entirely peer-review fact based except where noted. To address a couple of your very reasonable points of criticism. Point 1) Why is using HA to get peptides into the skin "sneaking?" Because the manufacturers don't tell you that they are using the hyaluronic acid as a penetrant. I know that's a subtlety. But it's important. Most people don't know that hyaluronic acid is a penetrant. And most people don't know that hyaluronic acid compromises the skin barrier. They just assume that the HA in the formulation is for "moisturizing." So by being silent on these facts and the real reason why they've included HA in the formula, the manufacturers are being sneaky. Not horrible, just sneaky. Point 2) Ingredients can be sensitizing on their own or they can enable or exacerbate sensitivity. HA has the latter two effects. We did not get into it in depth in the video but I've put a citation to the publication that shows how HA is pro-inflammatory in the context of skin sensitization. By the way, toll-like receptors are the receptors hit by HA, specifically TLR-2. Toll-like is the scientific name. I know that sounds weird. Point 3) Would be interested in knowing which brands tell you the molecular weight of the hyaluronic acid they include in the formula. The molecular weight of what they start with in the manufacturing process is very likely not what you get when you buy the product, and certainly not what you get when the HA is processed by the skin. The bigger point here is that the molecular weight of HA is only relatively important. Not absolute. ALL HA PENETRATES THE SKIN.