Gout, Pathophysiology, Causes, Symptoms, Risk Factors, Diagnosis and Treatments, Animation.
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- Опубліковано 23 тра 2021
- Gout disease is a common form of inflammatory arthritis characterized by recurrent attacks of painful joint pain. Category: bone, joint and muscles disorder, metabolic disorders.
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Cushing syndrome is a group of conditions caused by high levels of circulating cortisol or related corticosteroids.
A gout attack occurs suddenly, often at night. The affected joint is swollen, red and warm to touch. The initial attack usually involves only one joint, most often in the big toe, and lasts a few days. Subsequent flares may involve multiple joints and can last for weeks, with shorter intervals of remission in between.
Gout is caused by deposits of urate crystals in the joints, which may happen when blood levels of uric acid are too high. Uric acid is a waste product from the breakdown of purines, a major component of DNA and RNA. Because body’s cells are constantly renewed, uric acid is constantly produced and removed in urine. High serum urate level may result from decreased urate excretion, increased urate production, and/or overconsumption of purines.
The most common cause is the kidney’s decreased ability to excrete uric acid, which can be hereditary, or a result of kidney diseases, medications such as diuretics, alcohol use, or lead poisoning. Increased production of urate may occur in conditions with abnormally high cellular turnover or cell death, or in obesity, as urate production increases with greater body surface area. Overconsumption of purine-rich foods can contribute to higher urate level, but is rarely the only cause.
High concentration of urate promotes its precipitation and formation of crystals in joints, causing inflammation and pain. Because uric acid crystals form more easily in cooler temperatures, gout more often affects joints of the extremities. Urate crystals may also deposit under the skin around the joints, forming hard lumps, called tophi, that are not usually painful but can limit joint motions and lead to deformities. Joint damage caused by gout also increases the risk of developing osteoarthritis. In the kidneys, urate deposits may form stones, blocking urine flow.
Gout is more common in men. It often starts in middle age in men, and after menopause in women. Other risk factors include diets, obesity, other health conditions, family history, and surgery or trauma.
Diagnosis requires detection of urate crystals in synovial joint fluid. Because not all people with high serum urate levels develop gout, a blood test alone is not sufficient for diagnosis.
Acute gout attacks are treated with anti-inflammatory drugs, such as NSAIDs, regular use of which may also help prevent or reduce frequency of attacks. Because tophi can be dissolved by lowering serum urate, medications that block urate production or increase urate excretion may be used for this purpose.
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I wouldn't wish this on my worst enemy. I have a flare up now and it is brutal.. great video.
Same. Had this for like 11 years on and off but just put up with it. It’s crippled me. Misdiagnoses, extreme pain, I am crippled. I can’t walk, sleep, work, do anything. I’m in excruciating pain. Doesn’t help my ankles are damaged as well. Don’t know if this undiagnosed gout has been a contributor as I have no arch and flat feet, too. I’m bewildered that no medical profession looked into gout first off and checked my dad’s medical history. He has it. It’s hereditary. I’m not on allopurinol and have been for 4 weeks. It’s not really doing anything. Also find out by researching it that I should have been on colchicine as well which no one told me. I’ve started taking this, too but it’s not working and I’m at my absolute worst right now. So I concur. I wouldn’t wish this on anyone.
@@chshaw87 So sorry to hear what you're going through. When you say you're crippled is it the same feeling that gout gives you and it's all the time? because when I have my gout episodes they only lasted a few days. And usual one day or 2 that is the worst where it is actually excruciating pain and it's only in my foot and mainly my big toe where my bunyion is.
It may sound silly but you're also supposed to drink one glass of cherry juice every day when you're a gout patient of patient when you have pain or not. So do you have pain all the time or is it when you're having an episode episode?
@@yobabybubba if a flare up occurs, it will come on gradually and can last just shy of a week. so for example this came on last week and the pain has finally gone today. it doesn't help that an MRI has shown I have done damage to my ankles. I need surgery to repair and strengthen then. gout could have caused this being undiagnosed.
@@chshaw87 So you are saying that gout can cause damage where will you need surgery?
@@yobabybubba yes it can
I have a couple people in my family that have gout. I really don’t want this to happen to me so I’m trying to eat more better and exercise more 💪🏽
I have gout for a few years, I want to comment on how I have ""controlled" it" In addition to taking Allopurinol I have a diet, Ripe banana. (Not Banana) boiled well, then smoothie with strawberries and blueberries. Some Yogurts, (Not all) Meat, Yes meat, but Goat, Also Rabbit. and Tilapia Fish There is a Rice called Basmati. (Low GI), Crab too but from king crab. Tumeric helps too. Flour tortillas a little. Eggs Skim milk..,Some vegetables but not all. Avocado, Cilantro, Celery, Carrots, Zucchini, Eggplant, Taro, Nopal, A little pinto beans and a certain type of lentils. Potatoes (Not fried) If you like them fried, use an "air Frier" Good luck and Blessings!
It sad that this channel is not now recomending by youtube to all
but you all really doing a great job 😌😌🤗❤❤
Thank you... Love from India... Your videos are very helpful.....
Excellent
Plz cover more topics too .
*That will help all of medical students*
☀️☀️☀️❤️❤️❤️
Amazing video
This is very alarming at my young age. Thanks for this video.
I'm very happy to get this Channel..
Thanks a lot for the Team..
It is very useful for many of us..thank you so much
Visual explanations will be a chance for many tp understand better than text...
Once again Thank you 😊
so so nice thankes a lot aboute all this information
It is very useful.....👍...
Thank you so much 👍👍
Thanks for this video!
Thank you for this video... It will be useful for many medical students 😀👍
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PA school students too! 😊
You are right bro😂❤️🙏🏻
Very interesting and useful video..thanks 😍
The pain is unbelievable
I just got off work and had in and out attacks my whole ten hour shift..the pain was so bad my whole body went hot ..I almost threw up , became so dizzy .. couldn't focus or even breathe correctly
@@Ashley-rf8td I know it's so bad there is nothing I can suggest you do lie down keep your foot raised and eat or drink anything that could build your uric acid levels up ,fingers crossed it doesn't last to long
Good very good ❤
Excellent video
Im here because of king of the Hill with that episode where Bobby gets gout on his Toe
Yeah, he wanted to eat a lot of things like chopped liver, tongue, etc.
Thankyou for this vd
thank you 👍
In my case i have it in both knees and feet. Attacks would start from anywhere around a foot or a knee, sometimes even at the back of a knee. I was a non-meat eater (red meat and poultry) but i ate a lot of fish, so that may be the reason i developed gout. In the first five years only one knee or one foot could be in a flare up and would last from 3 days to a week. But then i started eating meats and poultry and the worst attacks came. Both my knees and feet are swelling and there is no way i can stand let alone walk to the bathroom, and attack duration is longer. The longest one i experienced was 2 months. I eliminated the meats again from my diet for good and im back to one knee or one foot per flare up. Having all four body parts swelling at the same time is the worst unpleasant thing to ever experience with gout. I literally walked with my hands under my butt to the bathroom and almost ate only rice with salt or sugar or any fruit in the fear that It might get even worse
Same with me. It hit me the day before thanksgiving and I'm glad I never ate all that food as I knew what was coming. Took two weeks off work and drinking a lot of lemon juice and cherry juice to flush it out.
I read a British Medical Journal report by two doctors thatclaimed gout is caused by fructose
Question,,yours came on all of a sudden..? Is there any special diet you are on?
@@sharonbateman3974 Not sure if you are asking me but if you are, this is something very misunderstood as I been researching it's causes, after the last time it hit me, I did a test, I have eaten all the foods that is believed to cause this and nothing so far, now it does comes suddenly at night and your knees or your foot starts to swell. I truly believe that since I stop exercising since I drive a semi, this gout creep up on me. On diet, they say drink lot's of cherry juice to flush your system if it hits you. I think it's a liver issue and diabetes issues starting up.
It seems you had the worst one, I'm having the gout in ankle of my right feet, and the pain is unbearable to walk, I need to use a cane to go to the bathroom and walk around 😢
Good job
fantastiic exlpanation thank you
Very informative
I have had Gout for years, and love red meat and beer, Alopurinol makes me shitty feeling, I take the methylprednisolone, and it's not helping this time, it is miserable to not do the things I want! I switch from beer to wine if I want to drink, or even Gin and Tonic, and have a water chaser between, I have wen't from 258lbs. to 189lbs., and guess what? I still have these attacks! it boils down to this....you almost have to be a vegetarian and don't eat or drink anything you like in life in order to prevent your Uric acid levels from going off the charts!
You dont have to be a vegeterian, but you must avoid acidic food and more consume alkaline food. It means consume fresh food more and more cause alkaline food will neutralize all acids including uric acid in your body. Avodi or rare consume food that cause acidic organism such as all diary products, all game meat, red meat, sugar, industrial sweetener, sugar drinks. You can consume and reduce chicken meat and eggs, and consume fresh vegetables. Drink 1,5 l water per day. Avoid stres.
Try Indomethacin 2/3X a day tablets. It works will real fast but only use it when painful flares ups or starting increase pain.
Try daily green tea, with lemon 🍋 and ginger and mint tea bags. For maintenance. Garlic 🧄, ginger and tuberculosis pills also helps maintaining detox kidneys/ toxic of organ out. Through unitary tract (peeing).
@911JayishSupremacy soaking the affected joints in espom salt with hot water really helps. It sucks giving up the beer that was hard for me but I couldn't take the gout anymore on my toe. Shit wasn't worth it.
Ya had to give up the Booze that was the hardest 😢 but the pain not stop was not worth it couldn’t even walk
Please upload video on rheumatoid arthritis... And different from gout..
Can u please? Thanks.
Thank you, for your good Explanation of STROKE Type & Treatment. Please Describe OVER ACTIVE BLADDER & Frequent Urination causing DISTURBED SLEEP and Consequent OBESITY , DIABETES Complicating to HEART ATTACK over Years of SUFFERING, Give us how to Treat with Proper Explanation and VIDEO.
They had a moment in Disenchantment when Zøg wanted to get a case of Gout. And soon he is aided by Luci the Demon and then he does have a swollen painful toe.
This is very painful 😔😔
I have been suffering from gout for 5 years...I'm only 18...I want to get relief from this pain..
Gout is the worst. Thanks for a great video explaining with the visuals.
Prevention is better than cure but doctors would make less money
Having one now 😢
And only if you've experienced gout in your feet would you know what it feels like every step you take is truly painful😊
My wrist s and hips are in such pain.
There's artwork I know of showing gout like a small imp sinking his fangs into your toe.
i want to ask you something my uric acid increase 7.8 and now after 1 month its 4.5 but the pain is there in my fingers and foot 👣 its is normal . when the pain will go
after death. i take medicine daily eat no meat no sugar no cakes no bread but still flare up after every week.
Can gout form in the soles of the foot after jogging?
Can a wild animal biting through my knuckle cause gout?
My first attack omg feel like iv got a broken toe worst pain
Oh Geez 😳
Great !! Now I know what I have 😢
Try prescribing for Indomethacin 50mg 2/3 a day for major flares ups. Works really fast under 12 hrs. Ice and Topic ointments. Intermittent for 12hrs+ with lots of lemon water, ginger green tea.
@@911jayishsupremacy So kind of you to leave a comment for me. Thank you!
@@darylclifford I just know how it feels looking for solutions, I just shorten your days of research.
@@darylclifford I know the pain trying resolve it quick as you can to get back mobile.
Good, brief
Sir mujh body kay refelective part’s samjh nh a rhy anyone help 🙏🏿
Thank you for this video. Question answered.
Interesting
Shadow wizard money gang
It hurts so much!
I have all gout in all my feet 😭
How many feet do you have?
I have uric acid in urine but no Gout, what does this mean?
I have little joint pain.
Michael Myers,
It is my understanding that uric acid is eliminated from the body through urine so everyone has uric acid in their urine. If your body has a high concentration of it and it is not eliminated quickly, the buildup crystalizes in joints and causes the attack. Perhaps you have a concentration that is within normal limits. When the labs came back from my first attack (one of the worst attacks) the level was "borderline." I would not expect so much pain from a borderline level! I sure hope you don't gave gout, its horrible...
@@bunkyman8097 I think the range was 360 something for the maximum and mine is 400. Pain level is very mild 2-10 I'm also experiencing TMJ pain right side of the jaw.
Michael Myers,
Naproxen helps if the is not too bad. Indomethacin is good for more painful attacks. Good luck!
@@bunkyman8097so pain is from uric acid?
@Michael Myers,
Yes, i believe the pain is caused by an over abundance of uric acid that, for whatever reason, is not eliminated. It builds up in joints that are cooler than the rest of your body and crystallizes. Its the crystals that cause the pain.
Hello, I also had the same problem for many years. After trying different medicines, I took Urico Savior from Yukti Herbs and recovered within 1 month. It is 100% Ayurvedic and worked the best for me. Must try it if you really want a solution.
How are you doing now ? Are you really a patient or are you trying to promote your product ?
its paining while watching🙄
1:19 how tf diuretics cause that
You'd do well to research this yourself rather than posing the question on youtube. "...diuretics increase urination, which reduces the amount of fluid in your body. But the remaining fluid is more concentrated, which can increase the risk that you'll develop the crystals that cause gout. Some types of diuretics also reduce the kidneys' excretion of urate, a component of uric acid."
Kaya pala mas lalong sumakit pagkatpos naming kumain kasi sardinas ulam namin. 😢
Bawal sardinas , mga internal parts like liver , dinuguan , sisig, beef , dilis at seafoods
My uric Acid is 10.6. Cholesterol 148. Blood pressure 118. Glucose 104 after eating.
Jetpunk euric acid
Is it normal to have gout for a month? I’m worried.
I believe once we get it, is for life.
@@rollzolo omg
Is this from me being a drunk? And there he said alcohol use
Couldnt people just get rid of this by healing their kidneys? instead of taking all that medication that probably makes their health worse
Turmeric with black pepper...trust me it's the solution
Mixed in a cup with water cold or hot?
P talk about suffering every step you take is painful
I HATE GOUT!
I find ice packs help
Or you could stop eating all the carbs and crap and get a proper diet
walang tagalog😇🙏
Bawal softdrinks , juice , alcoholic drinks, beers , seafoods, beef , sardines, dilis , dinuguan, sisig or mga internal parts like atay , balun-balonan, heart etc. Bawal sobrang rice or sweet breads
I was worried cuz my toe hurts but that’s it, it’s not red or anything.
Yeah turns out it’s because I sleep on my belly and my toe is at weird angle.
Gout is not caused by high uric acid!
I beg to differ.
then wat`s the reason
@@healthcare-pk Put it simple, it is because of brakage of body fliud flow.
DE CE NU VREȚI SĂ VORBIȚI ÎN ROMANEȘTE CRED AROGANȚĂ DISPREȚ.