Office Hours with Irene de Lázaro: Repairing Damaged Hearts

If you cut yourself, you will probably heal readily, since skin cells have the ability to regenerate. That’s not true, however, of the more than two billion cardiac muscle cells in the human heart, since most of those cells, known as cardiomyocytes, lose the ability to divide soon after we are born. That means that someone who suffers a heart attack, for example, will not grow new cells to replace those that die.
NYU Tandon Assistant Professor of Biomedical Engineering Irene de Lázaro is working to change that situation, by investigating the mechanisms by which in-vivo reprogrammed cells contribute to regeneration; studying the impact of mechanical and biochemical controlled perturbations on cell plasticity and reprogramming; and engineering reprogramming factor delivery vectors that will allow for efficient, safe, and clinically translatable reprogramming.
Read more about de Lázaro's work: engineering.nyu.edu/faculty/i...
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