Sir, I am using Mettler Toledo V10S. Sometimes my Karl Fischer reagent conc. decreased to below 4.5, hence this value not stored in system. Also there is no option to input titer value manually. Now, am I getting wrong results for samples?
Dear Rajib, you have to modify the program to include the K F factor below 4 5 also. Your system administrator can do this. Generally, there will not be any provision to enter manually in fully automated KF titraters. If the system is not operated as per instructions of the instrument, it is likely to give you erratic results.
In a kfr bottle for 5mg water consumes 1ml reagent, then factor is 5. But how to give 5 to 6, kfr solution strength decrease slowly so factor also below 5. Can you explain
@@ebersonleoraj6728 Even if the factor is below 5 mg/ml, it can be used to estimate water content. 5 to 6 factor is only a guiding reference. USP allows to use KF with lower than 5 factor. Is it clear now?
Generally, factor will be between 5.0 mg per ml to 6.0 mg per ml. You can also have up to 2 mg per ml KF factor for very low water content samples. Please refer USP for more details.
No detailed video like this on UA-cam .......very well explained sir ....need more explanations from you
Thanks for your compliments. You may indicate on specific requirement so that more such short videos could be made for your benefit
Sir can you please make a video on UV spectrometry operation,principle.
@@osmanali9629 There is one video on UV. You may check my links. Alternatively, please send your whatsapp number so that I can share it to you.
Sir can you please share a link of your Facebook account or Instagram account so that I can text you personally.
Go to Ramalinga Prasad Kuppa for Facebook
You are all rounder sir...
Your every video useful to us..
Thank you sir.. 🙏🙏🙏
Thanks. If you have any specific questions, you may indicate. I'll try to make video.
Super...sir...age plays crucial role here
Fantastic and very well explained. Well done sir
Glad you liked it!
You got many likes here congrats
Thank you
Superb teaching sir thank you so much
Very good teaching
Wonderful explanation 👍
Thank you
Good teaching I everseen
nice presentation :)
Excellent explanation sir.. If possible try to make video with KF apparatus, it may leads to understand much better
Sir, I am using Mettler Toledo V10S. Sometimes my Karl Fischer reagent conc. decreased to below 4.5, hence this value not stored in system. Also there is no option to input titer value manually. Now, am I getting wrong results for samples?
Dear Rajib, you have to modify the program to include the K F factor below 4 5 also. Your system administrator can do this. Generally, there will not be any provision to enter manually in fully automated KF titraters. If the system is not operated as per instructions of the instrument, it is likely to give you erratic results.
But if my factor is 4.9 so,can this is right or out of limit?
@gopalgirase-01 4.9 factor is OK. 5.0 to 6.0 factor is only a guiding factor. Read USP , you will fully understand the factor concepts
In a kfr bottle for 5mg water consumes 1ml reagent, then factor is 5. But how to give 5 to 6, kfr solution strength decrease slowly so factor also below 5. Can you explain
@@ebersonleoraj6728 Even if the factor is below 5 mg/ml, it can be used to estimate water content. 5 to 6 factor is only a guiding reference. USP allows to use KF with lower than 5 factor. Is it clear now?
@@ebersonleoraj6728 You can give the factor below 5 also.
But what is lower limit?@@pharmaworldk1473
Sir please prepare a video on GC and hplc
Sir,diff between moisture content &water content?
@@gopalgirase-01 both are same
difference between water content &loss on driying
LOD is total volatile content including any solvents. Water content by KF will give exclusively on water content.
Spr
What is the acceptance criteria limit sir
Generally, factor will be between 5.0 mg per ml to 6.0 mg per ml. You can also have up to 2 mg per ml KF factor for very low water content samples. Please refer USP for more details.
Tq sir
Sir what is acceptance criteria limit for kf standardization RSD..?
@@ojjaarundhathi7971 It is NMT1.0% or NMT 2.0%, depending upon the capability of the instrument on reproducibility.
@@pharmaworldk1473 tq so much sir
Telugu lo cheppandi sir plz
Do you want me to make the same video in Telugu?