Hey, thanks for the video - I did notice an error around the 9:30 mark. Sympathetic increases HR, SV & TPR. However, parasympathetics only have an effect on decreasing HR (their effect on decreasing SV is indirect, and they do not affect TPR at all). Wanted to point this out as it is important to understand! Cheers
The 4BloodPressureRemedy.blogspot.com has helped me to reduce my blood pressure (accurately 20-point cut) for 2 weeks only of utilizing it. Nevertheless, you need to exercise for about THIRTY-FIVE minutes daily. The feeling I have now is overwhelmingly content simply because my blood pressure is under the border line. .
You 4 above are all nuts. As to what you are saying, that's correct sort of, parasympathetics don't input on actual blood vessels, so they don't affect TPR that way. However, they do input on sympathetics and thereby CAN inhibit them and thus lead to vasodilation by inhibiting sympathetic drive, I am pretty sure.
Baroreceptors rapidly adjust your BP. Chemoreceptors rapidly adjust your ventilation (both are pretty fast). Those are the primary roles of the two systems. However, you're right to point out that chemoreceptors have cardiovascular effects as well and the brain basically takes input about blood pressure (baroreceptors) and composition (chemoreceptors) when "deciding" on the correct sympathetic/parasympathetic balance for the heart.
Vagus nerve does not end up in the midbrain, nor does glossopharyngeus nerve. Parasympathetics doesn't make blood vessels dilate. If the pressure is high the vasomotor center inhibits sympathetic system. Despite those the other parts are great. Thank you for illustrating and making things that we read easier to understand.
Jack L.Chen it may not play a role as important as adenosine, histamine, lactate, K+ etc. But that sympathetic cholinergic vasodialotor system do exsist. Cheers :)
Thank you so much for this demo. I am studying Paramedical Science and this was spot on! This really helped me understand Baroreceptors in maintaining BP. Thanks heaps!
Thank you so much, my friend introduced me to your videos when i was in high school and now i'm in university still using your videos. they are so helpful and i hate to admit this but they are perfect for last minute studies cause they just summarise everything so perfectly. you are honestly a life saver! I tutor kids as well, so i always show them your videos and share these
**NOTE** There are ONLY sympathetic innervations going to the smooth muscles of arterioles to cause BOTH vasoconstriction & vasodilation. The medulla oblongata will send more sympathetic signals to vasoconstrict arterioles, and the medulla oblongata will send less sympathetic signals in order to vasodilate arterioles. There are NO parasympathetic innervations that affect arterioles. My source is my Human Physiology professor and Human Physiology book by Silverthorn.
Greatest video! First of all, your voice is always so enthusastic that it is a pleasure to listen to all of your videos. And second of all, I could never figure out exactly what they were talking about when books mention, but do not really explain baroreceptors. I LOVE how you related everything to the formula--now vasoconstriction, dilation, and the action of aortic and carotid bodies makes TOTAL SENSE. THANK YOU!!!
Thanks Rishi. I am a first year med student in Australia. Your videos make tricky concepts super easy to understand. Please keep it up. You're awesome.
Great video as usual, one question. I thought that the ventricles only had sympathetic innervation, if that is true how does a parasympathetic response effect stroke volume? Thanks!
The 3rd branch of the aortic arch is the subclavian artery. The right subclavian branches off the brachiocephalic trunk. Great video overall, thank you!
We just learned about regulation of arterial pressure today. Our professor teaches from the BRS textbook. He told us that the parasympathetic autonomic nervous system does not affect blood vessels (i.e. arteries and veins), it only affects the heart. However Dr. Desai pointed out it does (10:12). Please help me out here... I am confused as to which one holds credible :(
This video is awesome .. but there is something wrong .. The parasympathetic NS Doesn't have a role in Blood vessels dilation ! instead, what causes vasodilation is the INHIBITION of the sympathetic NS.. isn't it? Thanks a lot :)
@@kylehallas2011 no actually the acetylcholine reduces the release of norepinephrine. neuropeptide y in contrast released from the sympathetic system inhibits the release of acetylcholine
Also believe that the parasympathetic nervous system provides no innervation to blood vessels. So less sympathetic activity will dilate the vessels and lose some of its tone. Likewise an increase in sympathetic activity will increase the tone and cause vasoconstriction. Good Video to clear out the cobwebs though.
Is it true that parasympathetic do not play a role in vasodilation; rather vasodilation is due to inhibition of sympathetic via inhibition of cardiac-activating center and/or vasomotor centers?
u said sympathetics increase the blood flow in not just the heart but all over the body(.but it does not increase the blood flow to cerebrum ) except it This is awesome video.
There are several important inaccuracies in this twelve minutes including the parasympathetic dilation and the fact that the brain area is primarily the brainstem not the "midbrain". This reflex arc changes heart rate on a beat to beat basis so that baroreceptors firing 20 or 30 times per minute would be useless - the actual number is closer to 50 action potentials per second. Sadly the facts are lost on the general public as long as it seems correct. The number of folks congratulating this video for its "knowledge" speaks loudly of quality control. Really a pity that this is what passes for education.
Mike Andresen Most of the people watching this aren't training to be doctors, he still gave me a good general understanding of the key concepts so I'm thankful.
The trouble with such a sentiment about UA-cam misinformation is that it suggests that facts are not as important as a slick presentation. Misrepresentation presents a huge challenge to the general public and contrary to the sentiment you state - indeed unvetted material like this is being used as fact by medical students being trained and presented by posting it, Kahn Academy represents it as accurate. Midbrain and brainstem are different parts of the nervous system. This is like making the case that 2+2 is approximately 5. It does matter and other unevaluated material placed on the web produces a haze of misinformation that you or iPhone-enabled practioners may use to make decisions. Facts and accuracy do count.
I'm studying to become a doctor and I use this as an extra studying method, if something isn't 100% clear, I turn to youtube but I do realise there are some inaccurate stuff, so my course notes are still the facts I trust and focus on.
Well that is certainly the better way but information is being monetized and could well afford to be vetted. Too many unquestioningly believe wiki sites and Kahn Academy as authoritative but at best they are inconsistent. Caveat Emptor.
Vasodilation is caused by a lower action potention of the SNS not the PNS. When vasodilation is needed in order to reduce resistance such as when BP is high, the SNS begins to send less signals, thus begining to relax the smooth muscles of the arterioles (tunica media). This is turn makes the lumen wider (dilated) leading to reduced resistance and hopefully a decrease in blood pressure (BP). Great video, very easy to understand
I wish that you were my physiology teacher :) Thank you very very much. I understood the issue completely. My lecture notes did not help me like you about this cardio-vascular system :D
parasympathetic can decrease the Stroke Volume? according to what i have been told, it is only sympathetic devision can actually decrease or increase the stroke volume!
+Jack Banister uhmm....i am not sure either. But it could be because parasympathetic stimulation has an inhibitory influence on the heart rate, so it would be more likely to decrease the Stoke Volume. Idk, i just thought there is a relationship between those, but i could be wrong! :)
Jack Banister you're both right. There's a mistake in the video: Parasympathetic nerves only innervate the pacemaker cells, so they can modulate HR, but not SV or TPR directly.
Great teachings, but if you can use legit markings in terms of numbers (ex. the amount of Action Potentials transmitted) instead of a random estimation that would really help out. Thank you for your consideration.
I think you also need to explain how this regulation mechanism relates to RAAS. Otherwise one might get the impression that the brain is the sole regulator of blood pressure, which obviously is not the case.
Acording to Ganong's Carotid sinus is a small dilation of internal carotid artery, just above the bifurcation of common carotid. Bt u said that the sinus are located main carotid artery below bifurcation. What is the correct one? 🤔
Absolutely! If you find these videos helpful, please spread the word! =)
Low BP is detected by baroreceptors and the reflex loop is to increase sympathetic output to the heart.
baroreceptors gets activated during high BP n activates NTS centre in medulla which leads to decrease in BP
Hey, thanks for the video - I did notice an error around the 9:30 mark. Sympathetic increases HR, SV & TPR. However, parasympathetics only have an effect on decreasing HR (their effect on decreasing SV is indirect, and they do not affect TPR at all). Wanted to point this out as it is important to understand! Cheers
The 4BloodPressureRemedy.blogspot.com has helped me to reduce my blood pressure (accurately 20-point cut) for 2 weeks only of utilizing it. Nevertheless, you need to exercise for about THIRTY-FIVE minutes daily. The feeling I have now is overwhelmingly content simply because my blood pressure is under the border line. .
You 4 above are all nuts. As to what you are saying, that's correct sort of, parasympathetics don't input on actual blood vessels, so they don't affect TPR that way. However, they do input on sympathetics and thereby CAN inhibit them and thus lead to vasodilation by inhibiting sympathetic drive, I am pretty sure.
What is heart rate? How we consider it important? What it represents?
Baroreceptors rapidly adjust your BP. Chemoreceptors rapidly adjust your ventilation (both are pretty fast). Those are the primary roles of the two systems. However, you're right to point out that chemoreceptors have cardiovascular effects as well and the brain basically takes input about blood pressure (baroreceptors) and composition (chemoreceptors) when "deciding" on the correct sympathetic/parasympathetic balance for the heart.
Vagus nerve does not end up in the midbrain, nor does glossopharyngeus nerve. Parasympathetics doesn't make blood vessels dilate. If the pressure is high the vasomotor center inhibits sympathetic system. Despite those the other parts are great. Thank you for illustrating and making things that we read easier to understand.
Indeed parasympathetic has a little effect on blood vessels of Penis... ?? It causes erection... :)
TRUE! But don't forget the sympathetic cholinergic vasodilator system seen in the resistance vessels in the skeletal muscles. Awesome video!
And... the 11 people who didn't like this video..why don't u do one on this topic n post it for us to see? :-)
+Nilupul Han Never heard about that before D: Is that system as important as local metabolites? K+, adenosin and nitric oxide?
Jack L.Chen it may not play a role as important as adenosine, histamine, lactate, K+ etc. But that sympathetic cholinergic vasodialotor system do exsist. Cheers :)
You are an excellent teacher. Thank you for taking the time to share knowledge with us.
I think you mistook subclavian artery for brachial. Brachial artery is a branch of axillary artery which is a branch of subclavian
Thank you so much for this demo. I am studying Paramedical Science and this was spot on! This really helped me understand Baroreceptors in maintaining BP. Thanks heaps!
Dr. Avery, is that you teaching us?
Thank you so much, my friend introduced me to your videos when i was in high school and now i'm in university still using your videos. they are so helpful and i hate to admit this but they are perfect for last minute studies cause they just summarise everything so perfectly. you are honestly a life saver! I tutor kids as well, so i always show them your videos and share these
**NOTE** There are ONLY sympathetic innervations going to the smooth muscles of arterioles to cause BOTH vasoconstriction & vasodilation. The medulla oblongata will send more sympathetic signals to vasoconstrict arterioles, and the medulla oblongata will send less sympathetic signals in order to vasodilate arterioles. There are NO parasympathetic innervations that affect arterioles. My source is my Human Physiology professor and Human Physiology book by Silverthorn.
I just realized cardiac out output and flow is the same. Thank youuuuuu
Truly a godsend. Thank you so much!!!
hey just wanted to say a huge thank you for the tutorials you've put up . Theyve been a massive help in grasping all the concepts.
Greatest video! First of all, your voice is always so enthusastic that it is a pleasure to listen to all of your videos. And second of all, I could never figure out exactly what they were talking about when books mention, but do not really explain baroreceptors. I LOVE how you related everything to the formula--now vasoconstriction, dilation, and the action of aortic and carotid bodies makes TOTAL SENSE. THANK YOU!!!
You're saving my life, thank you so much!
Yooo
that was so awesome! it is was really clear, concise and easy to follow thanks!
So clear and understandable. Thanks!
Thanks Rishi. I am a first year med student in Australia. Your videos make tricky concepts super easy to understand. Please keep it up. You're awesome.
are you a doctor now?
@@matthewmiller4045 haha
Great video as usual, one question. I thought that the ventricles only had sympathetic innervation, if that is true how does a parasympathetic response effect stroke volume?
Thanks!
Now you are a doctor 😅
Thank you so much for the video. I FINALLY understood. Thank you thank you. !!
Thank you! Great explanation!
The 3rd branch of the aortic arch is the subclavian artery. The right subclavian branches off the brachiocephalic trunk. Great video overall, thank you!
I wanna say,the video was amazing and i didn’t fell the time when i was watching the video,thank youu very much🤍
Bro thank you for the illustrations ❤
We just learned about regulation of arterial pressure today. Our professor teaches from the BRS textbook. He told us that the parasympathetic autonomic nervous system does not affect blood vessels (i.e. arteries and veins), it only affects the heart. However Dr. Desai pointed out it does (10:12). Please help me out here... I am confused as to which one holds credible :(
THANKKKKKKK YOU! finally found a video that explains it well!
your voice is so relaxing i went to sleep lol that's a good thing bc i don't go to sleep on no one
You have no idea how much this has helped me. Thank you so so much.
very clear explanation.thank you
Amazing!! Thank you.
Such a helpful video, never fails to broaden my understanding of topics i thought i would never get or had little knowledge on.. Great for exam prep!
This is awesome- Thank you!
thank you man!! the way you explained this was amazing!!
I love how he did draw a heart with a heart💖
Cute😂💕
This video is awesome .. but there is something wrong .. The parasympathetic NS Doesn't have a role in Blood vessels dilation ! instead, what causes vasodilation is the INHIBITION of the sympathetic NS.. isn't it?
Thanks a lot :)
The PNS doesn't inhibit the SNS, it simply overpowers it, it releases acetylcholine to the smooth muscle causing them to vasodilate
kylehallas2011
Baroreceptor r sphygmomanometer m kia difference ha plz.
Mohammad Bakri Thx for pointing that out! :)
@@kylehallas2011 no actually the acetylcholine reduces the release of norepinephrine. neuropeptide y in contrast released from the sympathetic system inhibits the release of acetylcholine
KHAN ACADEMY the best, respect though🙏
i like this video so much!
Excellent lecture.
Neat, colorful and concise.
This is the best explanation I have found. Thank you!
You're drawing the aorta attached to the right side of the heart?
Also believe that the parasympathetic nervous system provides no innervation to blood vessels. So less sympathetic activity will dilate the vessels and lose some of its tone. Likewise an increase in sympathetic activity will increase the tone and cause vasoconstriction. Good Video to clear out the cobwebs though.
Really helpful. Well done
Oh this helped me so much. Thank you physiology seems easier because of you :)
Great lesson, but lousy image setting. 360 is low. Needs to be at least 720 please
Excellent
So helpful and easy to follow, thank you
love it man
clearly explained. awesome!
I'm addicted to your videos...
+Viviana Han damn, i addicted on your
brilliant, thanks. have you done one on TBI autoregulation???
Thank you so much ❤️
Loved it! 💙
Thank you very much ,, really it is helpful
shouldn't this be the L. Subclavian and Brachiocephalic artery when talking abt the arches... otherwise great video
I came to the comments just to make sure it wasn’t just me
Actually its the left subclavian and left carotide arteries
Your videos are really great, thank you.
thank you my friend :)
Thanx Rishi for taking the time to share your knowledge with us!!!
you are amazing!! these videos are so helpful!
thank you ever so much, its amazing!
Love this vid! Thanks a lot!
Very helpful, thank you so much!
Well understanding
And what are volume receptors.. nd thanks great teacher u r..
Is it true that parasympathetic do not play a role in vasodilation; rather vasodilation is due to inhibition of sympathetic via inhibition of cardiac-activating center and/or vasomotor centers?
Awesome explanation. Thank you so much!
wonderful, thank you!
Thank youuu king❤💯
Its medulla not midbrain where they ends
I love you ... Thanks ever so much.😘
Now I will definitely pass my exam !!!
Such an awesome exercise session.
Great lecture
u said sympathetics increase the blood flow in not just the heart but all over the body(.but it does not increase the blood flow to cerebrum ) except it This is awesome video.
Thank you very much
RIGHT AND LEFT SUBCALVIAN ARTERY, the left comes directly from the arch or aorta and the right arise from the barachiocephalic artery :)
isn't the left subclavian artery the branch of the arch of the aorta and not the brachial artery?
Margarett Fortaleza true! but when subclevian artery enters the upper arm it becomes brachial atery so it isn't a big mistake I think.
Tamara Tamara thank you for that!!
Alaa A ..most welcome
am I the only one who thinks that this might be the same narrator as :Honey badger don't care"??
Great. well done khane ^^
There are several important inaccuracies in this twelve minutes including the parasympathetic dilation and the fact that the brain area is primarily the brainstem not the "midbrain". This reflex arc changes heart rate on a beat to beat basis so that baroreceptors firing 20 or 30 times per minute would be useless - the actual number is closer to 50 action potentials per second. Sadly the facts are lost on the general public as long as it seems correct. The number of folks congratulating this video for its "knowledge" speaks loudly of quality control. Really a pity that this is what passes for education.
Mike Andresen Most of the people watching this aren't training to be doctors, he still gave me a good general understanding of the key concepts so I'm thankful.
The trouble with such a sentiment about UA-cam misinformation is that it suggests that facts are not as important as a slick presentation. Misrepresentation presents a huge challenge to the general public and contrary to the sentiment you state - indeed unvetted material like this is being used as fact by medical students being trained and presented by posting it, Kahn Academy represents it as accurate. Midbrain and brainstem are different parts of the nervous system. This is like making the case that 2+2 is approximately 5. It does matter and other unevaluated material placed on the web produces a haze of misinformation that you or iPhone-enabled practioners may use to make decisions. Facts and accuracy do count.
I'm studying to become a doctor and I use this as an extra studying method, if something isn't 100% clear, I turn to youtube but I do realise there are some inaccurate stuff, so my course notes are still the facts I trust and focus on.
Well that is certainly the better way but information is being monetized and could well afford to be vetted. Too many unquestioningly believe wiki sites and Kahn Academy as authoritative but at best they are inconsistent. Caveat Emptor.
hey wait wont the vasodilation be unfavorable for lower blood pressure at 10:30
Thanks for the video!!! However, it's blurry to watch.
Vasodilation is caused by a lower action potention of the SNS not the PNS. When vasodilation is needed in order to reduce resistance such as when BP is high, the SNS begins to send less signals, thus begining to relax the smooth muscles of the arterioles (tunica media). This is turn makes the lumen wider (dilated) leading to reduced resistance and hopefully a decrease in blood pressure (BP). Great video, very easy to understand
SAPAIDERMANMO
vie
thank you so much!!!!! this video saved me
EyeYannie
GENERALLY, there is no parasympathetic innervation to the blood vessels
Thank you !!!!! :D i get it now
I wish that you were my physiology teacher :) Thank you very very much. I understood the issue completely. My lecture notes did not help me like you about this cardio-vascular system :D
thank you!
8 years ago 😮
No wonder u have got million subscribers
very understandable, thank you
The branches from the aorta should be subclavian instead of brachial
good lecture... thanks.. I learn something.. hehe
parasympathetic can decrease the Stroke Volume? according to what i have been told, it is only sympathetic devision can actually decrease or increase the stroke volume!
+ngoc pham same here, I've also learned that parasympathetic innervation has no effect on stroke volume (ventricular contraction).
+Jack Banister uhmm....i am not sure either. But it could be because parasympathetic stimulation has an inhibitory influence on the heart rate, so it would be more likely to decrease the Stoke Volume. Idk, i just thought there is a relationship between those, but i could be wrong! :)
Jack Banister you're both right. There's a mistake in the video: Parasympathetic nerves only innervate the pacemaker cells, so they can modulate HR, but not SV or TPR directly.
Great teachings, but if you can use legit markings in terms of numbers (ex. the amount of Action Potentials transmitted) instead of a random estimation that would really help out.
Thank you for your consideration.
I think you also need to explain how this regulation mechanism relates to RAAS. Otherwise one might get the impression that the brain is the sole regulator of blood pressure, which obviously is not the case.
Acording to Ganong's Carotid sinus is a small dilation of internal carotid artery, just above the bifurcation of common carotid. Bt u said that the sinus are located main carotid artery below bifurcation. What is the correct one? 🤔
very helpful (y)
awesome...:)
KA is always is the best.
What is the receptor that receives the stimuli for High blood pressure? is it the baroreceptor?
Então para que a pressão arterial baixar eu teria que fazer o que?