HER2 Testing in Breast Cancer: Is It Necessary?

Discover everything you need to know about HER2 Ultra Low breast cancer. Learn about its unique characteristics, diagnosis, treatment options, and prognosis. Stay informed with the latest research and advancements in understanding HER2 Ultra Low breast cancer. Whether you're a patient, caregiver, or medical professional, this video provides essential insights into this specific breast cancer subtype.
We’ll cover:
• Understanding HER2 Ultra-Low: What does this classification mean, and why is it crucial for personalized cancer therapy?
• Insights from DESTINY B04 and B06 Trials: A thorough breakdown of the findings and the transformative effects of Enhertu on breast cancer treatment strategies.
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Chapters
00:00 Introduction
00:18 HER2 biology
00:35 HER2 classsification
01:21 Trastuzumab Deruxtecan
01:32 DESTINY-B04 Trial
01:55 DESTINY-B06 Trial
03:19 Is HER2 Testing Necessary?
03:56 Antibody-Drug Conjugates in Development
04:09 Combination Therapy
04:37 Implications for Patient Management
05:34 Supportive Care
05:50 Future Research Directions
07:29 Conclusion
#her2 #breastcancer #cancer
About the Author:
Francisco Javier Esteva, MD, Ph.D., is a board-certified medical oncologist focusing on breast cancer research and treatment. He is the Chief of the Division of Hematology and Medical Oncology at Lenox Hill Hospital in New York City. He also holds the position of Director of Breast Medical Oncology for the Western Region at the Northwell Health Cancer Institute. Dr. Esteva is Professor of Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Prior to to his current positions, Dr. Esteva was a Professor of Medicine at NYU School of Medicine and at MD Anderson Cancer Center. He has contributed to the development of targeted therapy and immunotherapy of cancer. He is a Fellow of the American College of Physicians and an elected member of the American Society of Clinical Investigation.
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Disclaimer: The information provided in this video is for educational and informational purposes only and is not intended as medical advice. The views and opinions expressed by Dr. Francisco Esteva are his own and do not reflect the views of his employer or any affiliated institutions. Always consult with a qualified healthcare professional for personalized medical advice and before making any decisions regarding your health or treatment.