Quantitative real time PCR (qPCR)

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  • Опубліковано 30 лис 2024

КОМЕНТАРІ • 132

  • @morvolio-5223
    @morvolio-5223 Рік тому +20

    This is that guy on youtube that explains ambiguous concepts very well, which you are searching for. Amazing!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @emmaadams8797
    @emmaadams8797 3 роки тому +24

    Using this to prep for a mock interview tomorrow. You're a lifesaver. Thank you!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @rosegott3849
    @rosegott3849 3 роки тому +22

    Really well done, thanks! I wish someone had walked me through qPCR this well when I first started running them!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Please share my channel link with your friends and help me to reach big audience

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      I gave different playlists on different techniques , so don't forget to check out all of that

  • @rutovincentk
    @rutovincentk 4 роки тому +7

    This is the best explanation,I have ever seen I can now understand Real time qPCR

  • @jaydebpal1818
    @jaydebpal1818 3 роки тому +6

    very good overview. can you please make a detailed one on melt curve analysis and primer designing

  • @riseillyramos852
    @riseillyramos852 2 роки тому +2

    Omg i love you! Really wish my professor explained this well.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Lots of love from India 🇮🇳. Please share my channel link with your friends and help me to reach big audience

  • @kavitharachaiah8313
    @kavitharachaiah8313 2 роки тому +15

    Clear explanation. But do add some more text in your slides, like principle of the technique & lable each & every component in the slides. So that it will be much useful to us. Thank you.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +5

      Really glad to know it was useful. Please share my channel with friends. You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

    • @mdraismdsaman47mdsaman80
      @mdraismdsaman47mdsaman80 Рік тому +1

      😮😢😢😊😮😮😮😅😊😅😮😊😅😮😊😅😮😊😮😊😅😮😊😅😮😊😅😮😊😅😮😊😮😮😮😮😊😮😮😊😮😮😊😮😊😢😊😮😮😮😮😮😊😢😊😅😮😮😮😮😊😅

    • @mdraismdsaman47mdsaman80
      @mdraismdsaman47mdsaman80 Рік тому +1

      😢😮😢😢😢😅😢😅😮😢😮😢😮😮😢😮😮😮😊😅😮😢😅😅😅😅😅😅😅😮😊😅😮😢😮😮😢😢😢😅😢😮😊😅😅😢😅😢😅😢😅😢😊😮😢😢😢😅😅😢😅😮😢😅😅😮😢😊😅😅😊😮😮😊😅😊😮😢😢😊😢😊😅😮😢😢😅😢😢😅😢😢😢😢😢😢😢😊😢😅😊😢😊😮😅😊😢😢😢😅😢😮😢😅😮😢😢😮😮😅😅😅😢😢😢😅😅😢😢😢😅😮😅😢😊😢😅😊😮😊😢😊😮😢😅😮😮😮😮😮😮😅😮😊😅😅😮😊😮😊😅😮😊😮😊😮😊😮😅😅😮😮😊😮😮😅😅😮😅😅😮😊😅😮😊😮😮😮😮😮😮😅😮😮😮😮😮😮😮😮😮😊😅😮😊😅😮😊😅😮😅😮😅😮😊😅😮😊😅😮😊😅😮😊😮😊😮😊😮😅😅😮😅😊😮😅😅😅😊😮😮😊😮😮😊😅😅😮😅😮😅😅😮😊😅😮😮😅😮😮😮😮😮😅😊

  • @sadiqaisha4057
    @sadiqaisha4057 2 роки тому +1

    Thank you so much Arpan! I've never understood qPCR like I did in this 8 mins video!

  • @sheratajayasinghe448
    @sheratajayasinghe448 11 місяців тому

    The explanation was really good. N easy to understand. Thank you very much most of my doubts was cleared ❤

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  11 місяців тому +1

      Watch the detailed video ua-cam.com/video/tH_ozcFwQ_Q/v-deo.htmlsi=Y78Ps-hNVHvNBjoM

  • @moleculartraveler2481
    @moleculartraveler2481 2 роки тому +1

    This video is really well explained and helpful

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @BiswajitSaha-d2q
    @BiswajitSaha-d2q 2 роки тому +1

    He is a legend ....ARPAN is a LEGEND ....

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      I am not sure that if he is an ( whatsoever you have mentioned ). I know him personally, he had to do a lot of struggle in his life . Thanks for your compliments though.

    • @BiswajitSaha-d2q
      @BiswajitSaha-d2q 2 роки тому +1

      @@animatedbiologywitharpan rectified ..felt sorry

  • @humanityfirst5228
    @humanityfirst5228 2 роки тому +1

    You are gonna touch the sky 🌙

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Thanks for your compliments. Please share my channel link with your friends and help me to reach big audience

  • @kiplimosimon1429
    @kiplimosimon1429 Рік тому +1

    Excellent work

  • @fathimasulaiman5360
    @fathimasulaiman5360 4 роки тому +2

    Best explanation about real time pcr.... Really good 😍😍😍😍😍

  • @Universe12355
    @Universe12355 11 місяців тому

    Love your channel and the way you make difficult concepts easy.
    I had a question about primer property checking using Primer-BLAST.
    I have a primer that contains degeneracy/wobbles and I want to check its properties such as Tm, self-complementarity, self 3’ complementary using the primer- blast…
    However, when I use the primer Blast and search, it states that “ambiguity letters other than N are not allowed in the primer sequence”
    So that forced me to replace all the degenerate/wobble letters with N.
    Would that still make the property results correct? Am I still getting the right answers if they are replaced with N?
    Thank you so much, I would really appreciate some insight on this, as I can not find an answer anywhere.

  • @ominibioentrance6458
    @ominibioentrance6458 8 місяців тому +1

    Good explanations.......what if the ct value of control and treated sample are same say 26 for both. Does it mean that the transcript level is same in both.

  • @usrao2148
    @usrao2148 2 роки тому +1

    You are great teacher, !!!

  • @DrVRManoj
    @DrVRManoj 4 роки тому +2

    Very good lecture !

  • @ayat4522
    @ayat4522 3 роки тому +1

    sukriya , good video

  • @moussaeshra6212
    @moussaeshra6212 Рік тому +1

    What you mean by base line
    Like the first florescent ever or when it is above the threshold number?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому +1

      The baseline of the real-time PCR reaction refers to the signal level during the initial cycles of PCR, usually cycles 3 to 15, in which there is little change in fluorescent signal. The low-level signal of the baseline can be equated to the background or the “noise” of the reaction

    • @moussaeshra6212
      @moussaeshra6212 Рік тому +1

      @@animatedbiologywitharpan thanks alot dr

  • @ermionemariastavrouli8903
    @ermionemariastavrouli8903 Рік тому +1

    thank god your channel exists ahha

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @ZannaInnominata0126
    @ZannaInnominata0126 4 роки тому +2

    Great job, dude!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @spajder75
    @spajder75 4 роки тому +1

    Very nice video, but it would be great if there was subtitles

  • @SaumyaSharma123
    @SaumyaSharma123 3 роки тому +2

    What is the need to do qpcr over pcr sir?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Watch this video to learn ua-cam.com/video/_pMCwREQ22I/v-deo.html

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +2

      Please share my channel link with your friends and help me to reach big audience

    • @vamsikrishnagokarla5207
      @vamsikrishnagokarla5207 2 роки тому

      @@animatedbiologywitharpan this link is not opening sir

    • @amir91095
      @amir91095 2 роки тому

      with PCR you collect RFU data once the 40 cycles are complete vs qPCR you collect RFU data across all cycles; hence why q stands for quantitative

  • @cutieaadi9599
    @cutieaadi9599 11 місяців тому

    If I get a annealing temperature 66.4 and got single peak of melting curve, can I use that annealing temperature? While the Melting curve temperature range is 65_95’c ….what you suggest?

  • @gurralamohankumar5838
    @gurralamohankumar5838 4 роки тому +1

    Please make a video on 3' RACE and 5' RACE

  • @crlearning3460
    @crlearning3460 2 роки тому +1

    Hi. Is there a cell type qPCR only uses? Or is available to use with all cells?

  • @vaishnavidharmadhikari21
    @vaishnavidharmadhikari21 Рік тому +1

    Thank you sir

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      So nice of you. Please share my channel link with your friends and help me to reach big audiance

  • @ardranellikunnel7247
    @ardranellikunnel7247 2 роки тому +1

    Is sybr green specifically attached with the target gene?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      No no it can bind to any double stranded dna, but the pcr will selectively amplify the target gene so in the reaction tube there will be huge quantity of target with which sybr green can bind

  • @harshithaanand1742
    @harshithaanand1742 3 роки тому +1

    thank you so much was very very helpful

  • @Teejay_shan
    @Teejay_shan 8 місяців тому +1

    Sir I am checked hiv RNA quantitative pcr test result is target not dedicat meaning is negative hiv ? This is conclusive result ? Pls answer me😒

  • @dimpabhalru8063
    @dimpabhalru8063 8 місяців тому +1

    sir abhi window period mai hu sir actually next month mai canada jaaa rha hu pr m glti se hepatitis C ke contact mai agya hu … sir confirm nhi horha….. pls btao sir kuch 25 febuary ko needle use ki thi hep c postive ldke ki sir fr 10 din baad hcv pcr rna quantitative test krwaya …. Usme not detected aya … sir plss btao next test kab karwau ki accurate aajaye jldi mne canada jana h..
    pls help sir🙏🙏🙏

  • @Thomaspoa
    @Thomaspoa 4 роки тому +1

    The inventor of PCR, Kary Mullis, said that quantitative PCR was an oxymoron.

  • @lizhang2849
    @lizhang2849 5 років тому +3

    than you man, it helps

  • @hemantk345
    @hemantk345 6 років тому +2

    Awesome bro nice

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  6 років тому +1

      Thanks glad it helped you

    • @hemantk345
      @hemantk345 6 років тому +1

      I used to watch your videos bro this year i have secured AIR 256 but now I am pursuing biotechnology 2nd year i hope at the final year rank will be up

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  6 років тому +1

      Sure you would do great....stay optimistic

    • @hemantk345
      @hemantk345 6 років тому

      Thank u bro😇

    • @hemantk345
      @hemantk345 6 років тому

      Bro will u make a video on NMR (conceptual lecture)

  • @kocharkhasro387
    @kocharkhasro387 4 роки тому +1

    great

  • @harshithamohan4074
    @harshithamohan4074 2 роки тому +1

    Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @mtctafadzwa2318
    @mtctafadzwa2318 3 роки тому +1

    Well understood thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @monigopi2460
    @monigopi2460 Рік тому +1

    I cant find the Value analysis video

  • @sristi_2360
    @sristi_2360 3 роки тому +2

    Can qrt pcr be used to determine the exact number of viruses that have infected the sample?

  • @reyfranzheiropacardo5524
    @reyfranzheiropacardo5524 3 роки тому +1

    thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      If you like the explanation please share my channel link with your friends and help me to reach big audience

  • @SneufxWjehfyfr-v9z
    @SneufxWjehfyfr-v9z 2 місяці тому +1

    Lopez Edward Hernandez David Garcia Brian

  • @prajwalgosavi2001
    @prajwalgosavi2001 Рік тому +1

    Sir i recently done test rna pcr the sample was collected in heparin tube will this affect my result? Or the person carrying this test how will he know about inhibitors ?it was qualitative test.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      It's very difficult to tell, it depends what you want to detect ultimately

    • @prajwalgosavi2001
      @prajwalgosavi2001 Рік тому +1

      @@animatedbiologywitharpan it was related to virus detection about sti it was sent to thyrocare lab?

  • @sadiarajpoot7433
    @sadiarajpoot7433 4 роки тому +3

    Can anyone suggest me a book from which I can learn about Real time pcr

    • @alb4079
      @alb4079 4 роки тому +1

      Why did you like the comment, but didn't suggest any literature to this person?

    • @danaahmed8158
      @danaahmed8158 3 роки тому +2

      Introduction to biotechnology. By William J. Thieman and Michael A. Palladino.

    • @sadiarajpoot7433
      @sadiarajpoot7433 3 роки тому +1

      @@danaahmed8158 Thank you

    • @danaahmed8158
      @danaahmed8158 3 роки тому

      @@sadiarajpoot7433 😊😊😊

    • @lakindublin
      @lakindublin 3 роки тому

      Dorak's real time PCR

  • @ego9086
    @ego9086 Рік тому +1

    How can I contact you ,do you have what's up for contact sir?

  • @lawrencebishton9071
    @lawrencebishton9071 2 роки тому +1

    You mean you are torturing me electrinclyim a living man not an lab rat is this why my brain has been damaged

  • @gurralamohankumar5838
    @gurralamohankumar5838 4 роки тому +1

    Thank u so muchhhh sir

  • @watchfirst-p7z
    @watchfirst-p7z 2 місяці тому +1

    Thompson Paul Johnson Barbara Martinez Angela

  • @W5nli
    @W5nli 6 місяців тому

    How you got melt curve chart?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  6 місяців тому

      you can add melt curve after the standard PCR cycle

    • @W5nli
      @W5nli 6 місяців тому

      @@animatedbiologywitharpan can you explain more how?

    • @W5nli
      @W5nli 6 місяців тому

      @@animatedbiologywitharpan i use ncbl website

  • @leonweoow2746
    @leonweoow2746 2 роки тому +1

    is mlpa a qpcr type?

  • @fatimajahaf1412
    @fatimajahaf1412 3 роки тому +1

    is qpcr same as gradient pcr?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      No no gradient PCR is completely different from qPCR

    • @fatimajahaf1412
      @fatimajahaf1412 3 роки тому +2

      @@animatedbiologywitharpan what's the core difference please

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому +1

      I will upload a video on that. Just wait till tomorrow.

    • @fatimajahaf1412
      @fatimajahaf1412 3 роки тому

      @@animatedbiologywitharpan is bio rad the only manufacturer of gradient real time pcr?

  • @SneufxWjehfyfr-v9z
    @SneufxWjehfyfr-v9z Місяць тому +1

    Harris Ruth Smith Edward Young David

  • @77abhishekgupta74
    @77abhishekgupta74 8 місяців тому +1

    sir can i get this ppt?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  8 місяців тому

      You can buy it from our collection @3$ . Email us at arpanparichha1994@gmail.com if you want it. We will let you know how to do the payment

  • @sachinsarraf6708
    @sachinsarraf6708 6 років тому +1

    Can it is use for rabies detaction...

  • @WildeMarshall
    @WildeMarshall 3 місяці тому +1

    Jackson Anna Lewis Margaret Brown Cynthia

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @lorenzoceresa99
    @lorenzoceresa99 Рік тому +1

    too many ads

  • @weimullerjohann9118
    @weimullerjohann9118 2 роки тому +1

    viel intelligenter : ua-cam.com/video/IiHhuCXmpT8/v-deo.html