Joe Rogan Experience

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  • Опубліковано 9 вер 2019
  • David Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. His new book "Lifespan: Why We Age And Why We Don't Have To" is now available.

КОМЕНТАРІ • 4,7 тис.

  • @yamishogun6501
    @yamishogun6501 4 роки тому +2681

    0:00 The new book, resveratrol
    7:00 NMN and NAD+, metformin and exercise
    18:00 Sinclair’s family went on a safari
    32:10 Rogan's classic lion roar
    48:30 back to the anti-aging book, longevity
    52:20 Sinclair’s healthy 80 year old father: “He’s fitter than me”, his rebel grandmother
    1:10:00 intermittent fasting
    1:15:50 I.V. NAD+
    1:18:00 nutrition, yogurt
    and other food
    1:32:00 resveratrol, colorful foods
    1:41:00 sleep
    1:45:40 what should people be doing? (Sinclair is wrong about airport scanners)
    1:48:25 NMN and NR online
    1:50:25 CRISPR/ genetic engineering
    2:08:00 blood rejuvenation
    2:12:50 what is on the horizon? senescence cells, “We’ve learned how to fly…”

  • @apophis8118
    @apophis8118 4 роки тому +333

    THE MITOCHONDRIA IS THE POWERHOUSE OF THE CELL

    • @Sleepless4Life
      @Sleepless4Life 4 роки тому +8

      Thx captain obvious!

    • @tylermerlin8320
      @tylermerlin8320 4 роки тому +6

      ATP for life

    • @usaintwinnin7312
      @usaintwinnin7312 4 роки тому +2

      Apophis yayyy 7th grade biology

    • @choosefreedom4725
      @choosefreedom4725 4 роки тому

      Oh god brings back memories

    • @maxfrank13
      @maxfrank13 4 роки тому +8

      Without the midi-chlorians, life could not exist, and we would have no knowledge of the Force. They continually speak to us, telling us the will of the Force. When you learn to quiet your mind, you'll hear them speaking to you.

  • @TraitZZZ
    @TraitZZZ 4 роки тому +719

    Can we acknowledge how good those lion sounds were?

    • @kathleenbuckley4338
      @kathleenbuckley4338 4 роки тому +5

      Yes 🐆🐅

    • @orf.designs
      @orf.designs 4 роки тому +2

      Ikr.

    • @guynxtdork
      @guynxtdork 4 роки тому +30

      Look, Josh, when you refer to something in a video, especially one as long as this, you should always include a time mark. When the hell are the lion sounds. (Jk).

    • @TraitZZZ
      @TraitZZZ 4 роки тому +6

      guynxtdork rookie mistake , my bad mate

    • @muradaliyev9944
      @muradaliyev9944 4 роки тому +22

      @@guynxtdork 32:12

  • @MarcoMadrista
    @MarcoMadrista 4 роки тому +165

    Joe "At 22 I was basically a chimp" Rogan

    • @stevethea5250
      @stevethea5250 4 роки тому +1

      1:14:44 bull shit sounds like sinclair is hiding the secret

  • @gormleyl
    @gormleyl 4 роки тому +770

    "I took an edible and went to the zoo" is the most Joe Rogan quote ever.

    • @jotcw81
      @jotcw81 4 роки тому +4

      Lee Gormley Many great things started at Zoos. Check out “Me at the Zoo”.

    • @HyperintelligentViralSpider
      @HyperintelligentViralSpider 4 роки тому +6

      Dude its the greatest. We split a cookie and watch a giant eagle rip a squirrel apart

    • @taboomendoza8714
      @taboomendoza8714 4 роки тому +1

      Lee Gormley Seems like something you gotta do at least once

    • @akabuca96
      @akabuca96 4 роки тому +1

      deadass love the zoo

    • @akbutte5442
      @akbutte5442 4 роки тому +2

      I went to the zoo high, and seeing the African Elephants got me all the way fucked up.

  • @daniellopez2239
    @daniellopez2239 4 роки тому +525

    This guy's a legend, he told Rogan to blow him.

    • @skankhunt6066
      @skankhunt6066 4 роки тому +49

      More than once

    • @LahvUs
      @LahvUs 4 роки тому +9

      looked for this comment as soon as i heard it

    • @andyisdead
      @andyisdead 4 роки тому +2

      @@skankhunt6066 timestamp?

    • @koenigsforst_
      @koenigsforst_ 4 роки тому +29

      there's a lot of bi energy radiating from david

    • @CordovaIsland
      @CordovaIsland 4 роки тому +5

      He said he may have to blow him a couple of times. Didn’t even give him a number

  • @natacee566
    @natacee566 4 роки тому +639

    David Sinclair: I've unlocked the secret to eternal youth.
    Joe Rogan: Cool man, cool. Let's talk about animals eating each other for the next two hours.

  • @dlouise64
    @dlouise64 4 роки тому +59

    "How many wrinkles do you have? One, I'm sitting on it" 😂😂😂

    • @z3fs8
      @z3fs8 3 роки тому

      Lmao

  • @michaelsvoboda7680
    @michaelsvoboda7680 4 роки тому +771

    David “You May have to blow me a few times” Sinclair

    • @blendajeti6516
      @blendajeti6516 4 роки тому +40

      This guy made me uncomfortable at times and somehow I think he meant that lmfao

    • @Milanvaneijk
      @Milanvaneijk 4 роки тому +5

      @@mikieiacono8362 Alpha Queen, waaaaah. PERFECT description. 😂😂🤣

    • @RickR69
      @RickR69 4 роки тому +13

      What a legend.

    • @gman9035
      @gman9035 4 роки тому +5

      One is never enough

    • @GL0BETREKKER
      @GL0BETREKKER 4 роки тому +44

      That was funny as fuck bro, dude had me laughing. Breaks the whole "i'm just a smart scientist" dynamic.

  • @jacksoncamp1971
    @jacksoncamp1971 4 роки тому +408

    JOE, PLEASE HAVE PAUL STAMETS BACK ON THE SHOW. THANK YOU.

    • @epigeneticnerd4244
      @epigeneticnerd4244 4 роки тому +1

      He already did

    • @partsunknown9738
      @partsunknown9738 4 роки тому +1

      Health Nerdz when

    • @epigeneticnerd4244
      @epigeneticnerd4244 4 роки тому +3

      @@partsunknown9738 just type in Joe Rogan Paul Stamets dude lol

    • @4sername
      @4sername 4 роки тому +3

      Health Nerdz
      parts unknown wanted you to pull that up for him

    • @partsunknown9738
      @partsunknown9738 4 роки тому +11

      CatchCanista not true. If you read what the original commenter said, he was asking when will joe have Paul stamets “back on”. He’s only been in once. He wants him on again

  • @caboomcreations7190
    @caboomcreations7190 4 роки тому +102

    David Sinclair - "You can blow, You may have to do it a few times." *stares intensely w/ Straight face*

    • @guitawrizt
      @guitawrizt 4 роки тому +7

      Cannot believe BLOWJOBS entered a discussion on aging.

    • @joosepnilk6978
      @joosepnilk6978 4 роки тому +4

      guitawrizt I believe there to be a direct correlation between amount of blowjobs received during lifetime and life expectancy...or was it blowjobs given, I forget 🤔

    • @carryon5021
      @carryon5021 4 роки тому +3

      69 likes,but here,catch another one,😂😂!

  • @1994ramfan
    @1994ramfan 4 роки тому +50

    Sinclair: my father who is 80 is stronger than me
    Joe: That's embarrassing
    🤣🤣🤣

  • @putpentothepinnacle
    @putpentothepinnacle 4 роки тому +230

    That lion growling has got to take no1 on the top 10 Joe animal impressions list. So authentic.

    • @edwardcarrington3531
      @edwardcarrington3531 4 роки тому +4

      highview seeker lmao! Probably practices with his kids in the car and shjt

    • @TheBirdyyeses
      @TheBirdyyeses 4 роки тому +5

      Lmfao for real though. I was listening with UA-cam closed on my phone and I had to open the app and rewind to see if that was a recording or some shit.

    • @alanbolton7803
      @alanbolton7803 4 роки тому +2

      Always add a time stamp dude.

    • @j.f.kenedie9512
      @j.f.kenedie9512 4 роки тому +14

      32:13

    • @alanbolton7803
      @alanbolton7803 4 роки тому +1

      @@j.f.kenedie9512 thanx bro

  • @AndrewAttard78
    @AndrewAttard78 4 роки тому +242

    Joe talking about exercise, David talking about longevity, I'm all pumped eating pop tarts.

    • @Kittycat-rm8hu
      @Kittycat-rm8hu 4 роки тому

      Honestly if i see a future were no one can get old, saggy, fat, and slow because of some serum that would break my heart. I mostly want to make it to 90 or 100 like real old. There just something about geting old to me that is special. I dont want to see all the people i love die before my eyes but i want to just squeeze out as much years as i can get like making lemonade at every squeeze u loose more and more juice till its all out. Dry. Its sad but almost just buetiful. Life is so special but Too special for it last forever. I really wish to die at home no part of me wants to die in a hospital. I really feel alot that Im going to die young that im just not good enough to live a long time. Im going to be the nicest, coolest, meanest mf im going to make my family love me and take care me till im a dry lemon peel and bury me exume me and make decor out my bones.

    • @foreverdrift
      @foreverdrift 4 роки тому

      Lol!

    • @SamuelGomes-ed8ux
      @SamuelGomes-ed8ux 4 роки тому

      @@Kittycat-rm8hu go for it there are people who mutilate themselves and do group suicides trust me you're not that weird even though you must suffer some mental illness

    • @Kittycat-rm8hu
      @Kittycat-rm8hu 4 роки тому

      @@SamuelGomes-ed8ux ?

    • @Kittycat-rm8hu
      @Kittycat-rm8hu 4 роки тому

      @@SamuelGomes-ed8ux I said I want to live as long as I possibly can. I don't see how thats suicidal.

  • @daveb4628
    @daveb4628 4 роки тому +79

    Joe’s lion impression at 32:12 is crazy... I thought it was a real sound bite of a lion

    • @cooliipie
      @cooliipie 4 роки тому

      Same

    • @travis3371
      @travis3371 4 роки тому +3

      He is oddly good at sounds and impersonating

    • @jackfavier905
      @jackfavier905 4 роки тому +6

      Comedians usually practice sounds that they might need, Joe seems like the type of guy to make a lion joke

    • @kenbrunet6120
      @kenbrunet6120 4 роки тому

      lol pretty crazy how good it was

  • @Melungeonpeople
    @Melungeonpeople 4 роки тому +44

    I really like how down to earth and normal guy David Sinclair is.

  • @Arjun-eb1yc
    @Arjun-eb1yc 4 роки тому +461

    Get this guy on with Dr. Rhonda Patrick and just let them talk, see where it leads.

    • @kestergascoyne6924
      @kestergascoyne6924 4 роки тому +12

      Oh my God, thats a great idea!

    • @generousg83
      @generousg83 4 роки тому +12

      Would lead to the fountain of youth

    • @cameronc7756
      @cameronc7756 4 роки тому +24

      Rhonda Patrick actually interviewed him a while back (he shared on twitter), Guessing she decided to wait till his book launched to post it? Haven't seen it anywhere yet.

    • @dragoniousmaximus7304
      @dragoniousmaximus7304 4 роки тому +3

      And chris kresser

    • @Kalabei
      @Kalabei 4 роки тому

      This

  • @666slateran666
    @666slateran666 4 роки тому +377

    Gotta love David "You can blow me,you may have to a few times" Sinclair

    • @jonathaninteriano8389
      @jonathaninteriano8389 4 роки тому +18

      666slateran666 That was fucking hilarious😂

    • @brianhickey666
      @brianhickey666 4 роки тому +4

      💯

    • @thelyle1399
      @thelyle1399 4 роки тому +15

      Ron Burgundy Where were you taught to use teached?

    • @sniklenave6557
      @sniklenave6557 4 роки тому +1

      Kyle McClure lol his picture matches his comment perfectly... and I’m no Epstein suicide supporter either.

    • @MisterK-YT
      @MisterK-YT 4 роки тому +1

      @Ron Burgundy I was about to comment “teached?!” And then I saw who you are. My apologies good sir

  • @MicahsRants
    @MicahsRants 4 роки тому +158

    SERIOUSLY this is LITERALLY the EXACT same conversation they had on their first JRE podcast 8 mths ago. I thought I was going crazy for a moment but it’s almost word for word on some points.

    • @ChadsUltimateChannelExpereince
      @ChadsUltimateChannelExpereince 4 роки тому +12

      I'm sure you do the same thing, you just don't have a way to play it back and realize you're doing it

    • @andrewmoss8442
      @andrewmoss8442 4 роки тому +34

      I noticed the same thing and came looking at the comments just to see if I was going crazy...they say literally the exact same things, and neither seems to realize it. Like word for word in some cases. EDIT: Jesus Joe is even surprised by the same stuff. "My dad started a new career at 80" "at 80?!" and then the same exact thing in the next podcast...WTF. EDIT 2: Podacst 1: guys tells Joe about Chinese CRISPR experiment Podcast 2: Joe tell guy about Chinese CRISPR experiment.

    • @MicahsRants
      @MicahsRants 4 роки тому +9

      Andrew Moss YES!!! Lmao I seriously thought I was going fking crazy!!!!! It’s the exact same interview and like you said they don’t seem to realize it!!

    • @lisaproctor7276
      @lisaproctor7276 4 роки тому +1

      Yes I agree. It's the same convo. I noticed Dr.David Sinclair is not talking as much about MNM reversing aging. Now he is mostly discussing its affects on the eye.

    • @ButtersLStotch
      @ButtersLStotch 4 роки тому +4

      Truth. It has been less than a year since their first podcast though

  • @justingriebel7742
    @justingriebel7742 4 роки тому +284

    This guy looks exactly like a young Mr. Burns when he smiles

  • @blackfish9579
    @blackfish9579 4 роки тому +230

    David sinclair is like a benevolent Mr. Burns

  • @CK-ue7tz
    @CK-ue7tz 4 роки тому +174

    Funfact : when joe don‘t age anymore he can pod forever

    • @ThePyre666
      @ThePyre666 4 роки тому +2

      Exactly my thoughts hahaha

    • @Sjess25
      @Sjess25 4 роки тому +10

      I think after hitting 130, joe just moves to the isolation tank with a 50year supply of edibles... at 180 he comes out and establishes a new religion

    • @pradyumn2692
      @pradyumn2692 4 роки тому +1

      Also he can bow hunt and say *coyotes are everywhere* forever.

  • @thekevinwrightshow7032
    @thekevinwrightshow7032 4 роки тому +45

    I want this cat Sinclair to do the Audible reading for every book ever!

    • @alicyclicda3566
      @alicyclicda3566 4 роки тому +1

      He has a good tone w accent combo. You'd have to entice him to get out of his lab.

    • @bluEish04
      @bluEish04 4 роки тому +8

      He actually narrated his own book! It's on Audible

    • @elainey.4220
      @elainey.4220 4 роки тому +2

      Agreed. His voice has soothing effect.

    • @untetheredsoul4335
      @untetheredsoul4335 4 роки тому +1

      Yehs he's an Aussie but has a slight American accent, good mix.

    • @kiickinballistics
      @kiickinballistics 4 роки тому

      Looking forward to listening 👂 in the car this week.

  • @strategicthinker8899
    @strategicthinker8899 4 роки тому +143

    David: "I was at the wailing wall..."
    Joe: "How about that zombie movie with zombies piling on top of each other to get over a wall. It's a great movie."
    David: "Aha"

    • @demolitionwilliams
      @demolitionwilliams 4 роки тому +5

      Haha I've noticed he does that sht a lot

    • @temper44
      @temper44 4 роки тому +2

      That scene in the movie was set in Jerusalem, where the wailing wall is.

    • @stephencheney9811
      @stephencheney9811 4 роки тому

      @@temper44 He could have mentioned that.

  • @Irv123
    @Irv123 4 роки тому +702

    Joe should just keep having this guy on every six months and lets see how this mofo REALLY ages.

    • @faqat6790
      @faqat6790 4 роки тому +4

      Hahahahahaha I know right

    • @SodaMehPop
      @SodaMehPop 4 роки тому +97

      I love how everyone thinks this guy is a crook or that he's scamming people. He's literally a professor at Harvard and he wrote a book about genetics and aging, which is what he is actually a professor in.
      He's not out here selling snake oil, calm down people. Sure maybe he's wrong, that's why if you noticed every time Joe tried to get him to make a definitive statement he almost always said "well the evidence is good" or "we're not quite sure yet."

    • @notchbeard9007
      @notchbeard9007 4 роки тому +9

      @@SodaMehPop It's his claims, they are extraordinary and thus require extraordinary evidence. He also presents them in a very unscientific way stating things as fact when they are theory.

    • @Predator517
      @Predator517 4 роки тому +27

      @@notchbeard9007 yet he's trying to provide evidence of those claims, he's a fucking scientist, it's always impossible until somebody does it, remember what they (Einstein) said about the nuke, it is completely ridiculous to try harness atomic energy for weapons sake or for energy generation, then Japan found out the hard way it was possible, the cutting edge of science is the impossible, that's why it's so amazing

    • @GuillermoJonesJr
      @GuillermoJonesJr 4 роки тому +14

      Well he’s almost 50 and looks around the 40 year old mark to me so?

  • @superchallenging87
    @superchallenging87 4 роки тому +123

    David “you can blow me more than once” Sinclair.

  • @DaveKaiserIII
    @DaveKaiserIII 4 роки тому +3

    Thank you Jamie, Joe and David for sharing this information. Keep up the great work folks!

  • @afferent
    @afferent 4 роки тому +1

    I could listen to this man talk all day. He sounds like a guided meditation recording artist but he's speaking about neurology and genetics. I've fallen asleep trying to listen to it several times and I AM interested, these are some of my favorite subjects!

  • @AdamAarts
    @AdamAarts 4 роки тому +266

    “Hit it hard, let it recover” I’ll make sure to let my wife know, for science.

  • @Hectorinjeje
    @Hectorinjeje 4 роки тому +158

    Invite George Church please! He's from Harvard Medical School as well and the world leader in CRISPR technology!

    • @matm5695
      @matm5695 4 роки тому +7

      Héctor Sánchez Ned Daniel from unity biotech would be cool too

    • @kw3392
      @kw3392 4 роки тому

      YES!!

  • @DrMichaelMoeller
    @DrMichaelMoeller 4 роки тому +7

    I’ve had some really cool results with NAD IVs. I even do them on myself and feel energized and motivated for several days up to weeks.

  • @keypenn
    @keypenn 4 роки тому +3

    I love this guy so much, just watching this interview alone gives me so much hope and joy that our future is something to feel good about and look forward to. Keep up the good work and here’s to a better healthier world for us all :)

  • @pvtparts90
    @pvtparts90 4 роки тому +86

    Anybody else looking forward to episode 13,490 David Sinclair pt 150 when they're both in their 100s?

    • @B-RaDD
      @B-RaDD 4 роки тому +5

      That would be hilarious and also amazing

    • @ichoozjc
      @ichoozjc 4 роки тому +4

      It already happened....

    • @AngryOscillator
      @AngryOscillator 4 роки тому +2

      I'm hoping so

  • @Hosseinshafii
    @Hosseinshafii 4 роки тому +21

    My grandma just died at 100 years old - as long as I remembered she had this routine: dinner at 6 pm no eating until 9 am while from 7am to 8am exercised with empty stomach

    • @JJ-xr1qv
      @JJ-xr1qv 4 роки тому +2

      No hymen, no diamond.

    • @cin806
      @cin806 4 роки тому +3

      So she did intermittent fasting, basically. Neat. My grandfather is 90 and he stops eating at around 7 or 8 pm, until he wakes up, and then he gets a coffee and chills for like an hour before eating. He goes for a walk after breakfast. He isn’t on any meds and can still maintain his own large vegetable garden without help.

    • @Eddy-fq9mw
      @Eddy-fq9mw 4 роки тому +5

      My great grandma died about 10 years ago at 98, she ate a shit ton of desserts and ate breakfast lunch and dinner, so no fasting or anything like that. Never exercised other than cleaning around the house, cooking and taking care of her kids when she was younger. Her husband, my great grandfather also lived pretty long, died at 97, his job did require him to exercise a lot, he worked in the fields growing crops and attending his cattles and pigs but he also got a lot of sun from all the hours working outdoors constantly under the sun. My stepdads uncle would always eat as healthy as he could, workout and take care of his overall health, suddenly died in his 40's. Goes to show that longevity is mostly due to genetics.

  • @Libertas_P77
    @Libertas_P77 4 роки тому +2

    Another great episode with David Sinclair. I'd love to see him back on in another 6-12mths to get more longevity updates.

  • @boboband
    @boboband 4 роки тому +84

    🛑 ATTENTION 🛑 those that want suppliers for product. We've tested just over a dozen suppliers. Only two suppliers were telling the truth about their purity levels. Every single purchase from Amazon had NMN % below 50, despite all adverts saying 98/99 etc. Taking into consideration price, customer service, product purity and overall experience, our recommendation is a company called DoNotAge.
    Their website is www.donotage.org
    Hope this helps folks x

    • @teebeecan9806
      @teebeecan9806 4 роки тому

      @@oldsore Hi just curious how long you have been using this supplement from donotage for?

    • @joannewebb5090
      @joannewebb5090 4 роки тому +1

      Another vote for Do Not Age. I was really nervous buying online - don't trust any of them! The DNA team helped me with all my questions and delivered my NMN on time. I've since bought another two packs for the family 😁

  • @corydean2330
    @corydean2330 4 роки тому +166

    David Sinclair busted the joke near the end “You’re gonna have to blow me a few more times.” Just gained mad respect.

    • @Gizz2Brizz
      @Gizz2Brizz 4 роки тому +3

      He may have meant it

    • @pandamonium8182
      @pandamonium8182 4 роки тому +2

      He def wasn't afraid to tell joe he could blow him

  • @gabrielgonzalez1993
    @gabrielgonzalez1993 4 роки тому +65

    I really appreciate the amount of respect joe gives this man.

  • @ACTHdan
    @ACTHdan 4 роки тому

    So glad to have a sort of supplemental lecture companion to his book. I’d highly recommend Dr. Sinclair’s book to anyone interested in the biology behind longevity and tips to slow aging.

  • @dvlpr
    @dvlpr 4 роки тому +1

    This is the best episode I've ever watched. We need David back on in 2020!!!

    • @FootnotesToPlato
      @FootnotesToPlato 4 роки тому

      4 months they are scheduled to do this again. Btw there is another one of these already

  • @paulst6862
    @paulst6862 4 роки тому +271

    Oh, that vampire guy is back on.

    • @redwolf4203
      @redwolf4203 4 роки тому +5

      He looks eastern European af

    • @Sleepless4Life
      @Sleepless4Life 4 роки тому

      It's the eyes isn't it? Lestat and shit.

    • @danfontaine8179
      @danfontaine8179 4 роки тому +2

      It looks like his face isn't making the sound of his voice loool

    • @vitg7
      @vitg7 4 роки тому +4

      Paul ST hea scary right? But that kinda makes him cool, everyone can relay, everyone has a friend like that, he’s fucking weird and sometimes creepy but you just realize that everyone is different and thats cool how our species are.

    • @isaac13d
      @isaac13d 4 роки тому +1

      Ha, and they were talking about getting young peoples blood too....

  • @jennifermurillo8364
    @jennifermurillo8364 4 роки тому +97

    I like his sense of humor. Remember adults suck, and humor will keep you young.

    • @valentingrozdev2111
      @valentingrozdev2111 4 роки тому +1

      You will become adult and it's more problem for women, than for men.

    • @jaimietaylor4724
      @jaimietaylor4724 4 роки тому

      Jennifer Murillo yes

    • @jennifermurillo8364
      @jennifermurillo8364 4 роки тому +2

      I am an adult but my humor keeps me young Valentin Grozdev. Plus all the adulting really sucks!!! Male or female or what ever, when you're an adult it sucks!!!! So just laugh about it!!! 😁

    • @mikeguliano3159
      @mikeguliano3159 4 роки тому

      @@jennifermurillo8364 I think that's why Joe is such a positive person. Doesn't seem to take life too seriously

    • @Alistair
      @Alistair 4 роки тому

      @@jennifermurillo8364 I dunno, I quite enjoy being able to drink and drive. Not at the same time though

  • @SideSpin11
    @SideSpin11 4 роки тому +5

    This conversation is so refreshing after listening to the NDT podcast

  • @R3vAnGe123
    @R3vAnGe123 4 роки тому +25

    «At 22 I was basically a chimp” 😂😂

  • @carlogaytan7010
    @carlogaytan7010 4 роки тому +210

    *I watched this at 2x speed so now I will live 2x longer*

  • @joshamaya196
    @joshamaya196 4 роки тому +40

    32:13 holy cow, those were some authentic lion growls.
    I'm pretty sure this confirms Joe is one of those animal hybrids Alex Jones was talking about

    • @adamg5780
      @adamg5780 4 роки тому +1

      Joshua Amaya ikr, remember when he did the bear sounds talking about getting eaten by one?

    • @goldschool9050
      @goldschool9050 4 роки тому +1

      Gold Joshua Gold!

    • @FREEDOMFORUKRAINE2024
      @FREEDOMFORUKRAINE2024 4 роки тому

      Remember the 800 pound gorilla 😂

  • @robertwelch2843
    @robertwelch2843 4 роки тому +8

    As a kidney transplant patient, when I was on dialysis before my transplant, my dietitian recommended the process Joe explains at 1:29:020. It also reduces phosphorus content

    • @ShinyMudkip914
      @ShinyMudkip914 4 роки тому +1

      Thanks for commenting! Interesting 😊

  • @MDZac2024
    @MDZac2024 4 роки тому +1

    Joe Rogan's podcasts set the benchmark. Huge variety in guests, super interesting topics, and humor/entertainment.

  • @Aelwyn666
    @Aelwyn666 4 роки тому +17

    I thoroughly enjoyed the previous Podcast with Dr Sinclair and this Podcast topped it. What a brilliant and fascinating person! I wish him great success in his endeavours.

  • @TronApostle
    @TronApostle 4 роки тому +10

    The survivor man episode they’re taking about with the Flamethrower towards the Lions is literally the ONLY ep I ever saw! Was tremendous

  • @JeMiT222
    @JeMiT222 4 роки тому

    What are the best health and fitness JR vids? There's so many i don't know where to startttt

  • @starflower666
    @starflower666 4 роки тому +29

    we want to meet his 80y dad!

  • @gamebred26
    @gamebred26 4 роки тому +231

    I can't believe this guy is 85 years old.

    • @alexhise968
      @alexhise968 4 роки тому +3

      He's not.... did you listen?

    • @NDC1234
      @NDC1234 4 роки тому +21

      Lol well played 👍

    • @jotcw81
      @jotcw81 4 роки тому +31

      gamebred26 You didn’t quite pay attention.
      He is 122.

    • @ja--getti6593
      @ja--getti6593 4 роки тому +15

      Wtf I thought he was 183

    • @Nev-xf8oe
      @Nev-xf8oe 4 роки тому +9

      he is actually 69

  • @LucaBacigalupo
    @LucaBacigalupo 4 роки тому +89

    Did Joe forget his last conversation with David?

    • @hhijazi6296
      @hhijazi6296 4 роки тому +8

      Exactly, I checked the comments right after Joe asked Sinclair how "biological age" is measured. In episode #1234, Sinclair answered this question. I mean to be fair, nobody's memory is perfect, so I don't mean to attack Joe or anything.

    • @brotothewilliams9890
      @brotothewilliams9890 4 роки тому +3

      @@hhijazi6296 hes doing it for the fans and he also wants to relearn what he was told to make sure he remembers the answer

    • @karolyhorvath7624
      @karolyhorvath7624 4 роки тому +2

      What makes this even stranger is that in the last conversation Joe took a lot of notes.

    • @stevethea5250
      @stevethea5250 4 роки тому +1

      @@brotothewilliams9890 al-Hijr al-Aswad (The Black Stone)
      The Black Stone is a stone, considered by scientists to be a meteorite or of similar origin and believed by Muslims to be of divine origin. It is set in a corner of the Ka'bah and it is Sunnah to touch and kiss the stone. The area around the stone is generally always crowded and guarded by policemen to ensure the pilgrims' safety.

    • @sokmkim5057
      @sokmkim5057 4 роки тому +5

      Broto theWilliams yes and they talked about fixing teeth and Joes miniscus tear thing again like DEJAVU

  • @ilirademi4016
    @ilirademi4016 4 роки тому

    My grandfather was one these guys stopping smoking at 90 :) he was tough guy, when it comes to keeping on working until he died.

  • @liamkneeson8866
    @liamkneeson8866 4 роки тому +26

    When he said he saw a lion tear apart an impala I thought he meant a Chevy for a solid couple of minutes.

  • @beco89inc50
    @beco89inc50 4 роки тому +137

    Joe “who do I need to blow” Rogan

    • @LiamE69
      @LiamE69 4 роки тому +19

      David "You can blow me" Sinclair

    • @gman9035
      @gman9035 4 роки тому +3

      If I had a nickel....

    • @alexsorto6183
      @alexsorto6183 4 роки тому +5

      came for this comment, didn´t dissapoint! Take my like!

    • @demolitionwilliams
      @demolitionwilliams 4 роки тому +2

      @@MaX-yx2cm hahaha clicked on the timestamp and knew what I was abt to hear but for some reason still made me laugh

  • @raymondmyers100
    @raymondmyers100 4 роки тому

    I love David's honesty and willingness to say I don't know, but this is what I think it could be. I wish every "expert" had this outlook. After all, our knowledge no matter how big will always be limited, but the amount of things we don't know will always be infinite.

  • @mostaanroya
    @mostaanroya 4 роки тому +17

    Dr Sinclair you don’t need those packets for making yogurt, just put a tbsp of yogurt in the milk 😀

  • @andrewe3165
    @andrewe3165 4 роки тому +15

    This is one of the best JREs for some time, David is literally the perfect person for Joe's style and it's a big plus that Joe has some interest and knowledge on the subject

  • @tkr4693
    @tkr4693 4 роки тому +394

    This dude has that type of “evil genius” face

    • @CultofThings
      @CultofThings 4 роки тому +44

      Like a supervillain pre-lab accident

    • @mneo212
      @mneo212 4 роки тому +19

      A young Mr. Burns

    • @Alistair
      @Alistair 4 роки тому +1

      ever watched The Boys? He looks like a younger version of Homelander

    • @brianhickey666
      @brianhickey666 4 роки тому +2

      @14miki ummm no

    • @deleted836
      @deleted836 4 роки тому +5

      14miki Source? Even though I’m 99% sure that he’s using Botox looking at his weird facial expressions and bloated face, I thought his work is legit at least.

  • @guitarlearningtoplay
    @guitarlearningtoplay 4 роки тому +10

    *warning Resveratrol can be cytotoxic at high levels

  • @atme365
    @atme365 4 роки тому +4

    This was great, I love it, gives me hope for humanity ❤

  • @hunterw6938
    @hunterw6938 4 роки тому +466

    Joe definitely blew him when they were done filming.

    • @peterbabicki8252
      @peterbabicki8252 4 роки тому +31

      A couple of times.

    • @KPatrolis250
      @KPatrolis250 4 роки тому +13

      I would too if I can regenerate my body like freaking wolverine

    • @mr.fingers
      @mr.fingers 4 роки тому +6

      nah, Brendan would snitch on him again, he learned his lesson.

    • @ripped2shredz238
      @ripped2shredz238 4 роки тому +4

      He put him in a rear naked choke.literally.

    • @Sleepless4Life
      @Sleepless4Life 4 роки тому +3

      Standard protocol then.

  • @Bonfefe
    @Bonfefe 4 роки тому +41

    This guy's awesome. Glad he's back

  • @JoelxCruz
    @JoelxCruz 4 роки тому +1

    I’m totally fascinated about all this and the metformin, nmn, nad and resveratrol!!

  • @roberttudor455
    @roberttudor455 4 роки тому +8

    Who reads anymore ? I just watch Joes podcasts ... :)

  • @edm8777
    @edm8777 4 роки тому +85

    He gets a thumbs up JUST for pulling the mic up close without being told.

    • @kirekreppein8293
      @kirekreppein8293 4 роки тому +1

      He did get told throughout

    • @edm8777
      @edm8777 4 роки тому +2

      Kire Kreppein i just mean right at the start

    • @blickygobrrrrr
      @blickygobrrrrr 4 роки тому +2

      He kept it about a fist from his face. 😂🤣😅

  • @mariekirby1683
    @mariekirby1683 4 роки тому +9

    Sinclair looks like Mr Burns when he smiles.

  • @Alex-kk8is
    @Alex-kk8is 4 роки тому +3

    I love how joe swears and jokes about meth etc to these academics he interviews. Really makes my day :)

  • @ariangx1929
    @ariangx1929 4 роки тому +2

    this man give world so much hope

  • @jasc1893
    @jasc1893 4 роки тому +432

    He needs to pull that mic up about a fist from his face

    • @jewhammer
      @jewhammer 4 роки тому +22

      Not surprised that Joe uses a fist as a unit of measurement.

    • @mrmadisonlv
      @mrmadisonlv 4 роки тому +17

      He also needs to sip a DMT milkshake and go on an night elk hunt

    • @hamschh
      @hamschh 4 роки тому +6

      I know wtf it's 2 fists away

    • @questly6918
      @questly6918 4 роки тому +11

      *pull that sucker

    • @samerumrantech
      @samerumrantech 4 роки тому

      I cant hear the Dr. at all

  • @JohnnyRebKy
    @JohnnyRebKy 4 роки тому +156

    Dammit where is Randal Carlson!!!

  • @calebray4168
    @calebray4168 4 роки тому

    Fascinating stuff as always. I can’t wait to slowly start augmenting my body and become younger smarter and stronger...

  • @Shieldsofshame
    @Shieldsofshame 4 роки тому +6

    Joe, thank you brother for this, YOU saved my life!! Because of this video I have lost 100 pounds, stopped drinking and have adopted for the most part David's lifestyle, I stopped taking Tru Niagen , stuff is not cheap bro. I do take 500 MG Metformin, easily prescribed,l Resveritrol and I just ran out of NMN but the fasting is what chaged the whole game, man I tell you what, not eating for 3 days is easy for me now, but my regular schedule is once every 24 hours, been doing it for 9 months now. I am making a video on it and trust me bro, I will be referencing this video, man there is no telling how many lives you impacted with this!!!! I have been a fan since you started with the UFC way back in the early to mid 90's , my memory escapes me. But Thank you and to David as well, I bought his book and it is great!! I am at the lowest weight of my adult life, I will be 50 this year and I feel like I am in my 20's, I am not bullshittin u! Love you bro, thanks so damn much for saving my life!!!!!!!

    • @Woodwardx
      @Woodwardx 4 роки тому

      I heard metformin was recalled how is your health now?

    • @Shieldsofshame
      @Shieldsofshame 4 роки тому

      Hoozbad I stopped taking after 2 months. I lost 116 pounds and in the best health of my life!! I achieved that goal March of this year , 2020. I also have a UA-cam channel, you can see me in my videos. I feel like a million bucks and it’s all thanks to Joe and David!!! Peace bro, hows your health?

    • @Shieldsofshame
      @Shieldsofshame 4 роки тому

      Metformin is not how I lost the weight tho.

  • @LarsRichterMedia
    @LarsRichterMedia 4 роки тому +211

    Chemicals, we don't get them from the stars, we get them from Earth.
    ... Luckily you didn't say that during the Neil DeGrasse Tyson Podcast

    • @jotcw81
      @jotcw81 4 роки тому +16

      Lars Richter Yeah, that was one of a few moments where there momentum took them a bit too far.

    • @jimothyj2638
      @jimothyj2638 4 роки тому +7

      @@Dom0831 basically Tyson was the Chad and Rogan was the virgin of that conversation

    • @NoveltyKnown
      @NoveltyKnown 4 роки тому

      SAME THOUGHTS hahahaha

    • @ichoozjc
      @ichoozjc 4 роки тому +8

      Lol, as if NDT would have let him get a word in 🤣

    • @ADerpyReality
      @ADerpyReality 4 роки тому +1

      Well stars and that become earth. Jeez.

  • @looshkin66
    @looshkin66 4 роки тому +22

    You never truly make it till Joe invites you back a second time.

    • @alexhise968
      @alexhise968 4 роки тому

      Haven't seen Les Stroud on again

  • @clydekelvinandthesinners.3977
    @clydekelvinandthesinners.3977 4 роки тому

    I would love to interview Rogan, he has talked in depth with all the most interesting people alive today, he must be a fantastic man to talk to.

  • @travis3371
    @travis3371 4 роки тому +2

    Definitely enjoyed this podcast Joe!

  • @ThomasTheFapEngine
    @ThomasTheFapEngine 4 роки тому +92

    This dude is the male version of Gale the Snail from Always Sunny

  • @jaydenboyer9619
    @jaydenboyer9619 4 роки тому +33

    Ah yes. The mitochondria is the powerhouse of the cell

  • @IngestedTransmitter
    @IngestedTransmitter 4 роки тому +5

    I wish for Joe Rogan to interview Peter Fenwick on near death experiences.

  • @MrKeilstrup
    @MrKeilstrup 4 роки тому +267

    Elon Musk please make a startup within this field 🙏

    • @davidcadman4468
      @davidcadman4468 4 роки тому +27

      He has, it's called Neuralink. It is in it's primitive stage. Think of Alexander Graham Bell, inventing the Telephone. Leap forward to the Apple/Android/Huawei smart phones. That's where Neuralink is going. But it won't be external like smart phones, but it will be an internal replacement for smart phones, with a host of other technologies, that will converge on it. It started a couple of years ago, but it won't take a century to reach a tipping point, where aging and disease will be a thing of the past. I give it a maximum of 25 years when it will be feature rich. In the meantime, like the development of the telephone to cell phone it will acquire features on a linear line, until it hits the knee curve of exponential growth. What Prof. Sinclair hasn't commented on, is the power of A.I. to influence development of Anti-Aging Science. We are seeing it with DNA; discovered in 1953, Genome Project 1989, to 2003 at billions of $. Now we are looking at within the next 5 years having the ability to read genomes in doctor's offices as easily as we do blood pressure. With the extra ability to remodel stem cells, and create Stem Cell Therapies, for diseases we get as we age. As far as the future 25 years out, this is one of the easiest ones to predict. The rest, you ain't seen nothin' yet baby! That Queen song, we will rock you!! comes to mind. LOL

    • @smp1017
      @smp1017 4 роки тому +34

      Neuralink doesn’t have anything to do with Anti Aging lmao. You clearly don’t know enough about BMIs to understand what they’re actually doing

    • @aryangod2003
      @aryangod2003 4 роки тому +11

      You can consider people like Sinclair and George Church as the Elon Musk of Life science and genomics.

    • @mathewriedhammer7175
      @mathewriedhammer7175 4 роки тому +3

      Stephen Mp I think you are missing his connection though

    • @MixedGreneMC
      @MixedGreneMC 4 роки тому +1

      This comment needs more likes.

  • @radwizard
    @radwizard 4 роки тому +6

    Rad! Been waiting for this rerturn. Thank You JRE team.

  • @majorkade
    @majorkade 4 роки тому +115

    Word is Joe is going to blow him for an entire three hour podcast in order to slow down aging.

    • @er297553
      @er297553 4 роки тому +2

      Omg you guys are ridiculous! 🤣🤣🤣

    • @Anonymous-dp2vp
      @Anonymous-dp2vp 4 роки тому +10

      Sinclair - You have to blow me possibly a few times to turn back the clock a decade.
      Rogan - I'm not falling for that again.

    • @jaydarklighter1989
      @jaydarklighter1989 4 роки тому +1

      Joe had a bit about having a buddy who has a time machine that eerily went down a very similar sign-up model of mouth-based cock-holstering

    • @Neishy4AGTE
      @Neishy4AGTE 4 роки тому

      Ragin

    • @SlyYevon
      @SlyYevon 4 роки тому

      For science!

  • @CarolCarolDoddDodd
    @CarolCarolDoddDodd 4 роки тому +10

    Who is here for stock tips and wishes they had been here sooner🤦🏼‍♀️

  • @user-lf2vw5dw6d
    @user-lf2vw5dw6d 4 роки тому

    I also made yogurt for my family and now always have to make it, they love it! I wish I knew what starter he is talking about. I just use some starter from the last batch.

  • @71whitey
    @71whitey 4 роки тому +312

    ok, makes shopping list for today: chicken, brown rice, toilet paper, DHEA, Growth Hormone, Metformin...."

    • @user-ik5ze1sh7i
      @user-ik5ze1sh7i 4 роки тому +26

      @Peter Lustig the majority of joe rogans guests are on some type of drugs, I love how they talk about this anti aging technologies but don't mention only the wealthy will have access to it, and they will use it to keep humanity enslaved

    • @wakwak7511
      @wakwak7511 4 роки тому

      os terminal sickening

    • @grubbybum3614
      @grubbybum3614 4 роки тому +33

      @Peter Lustig what do you mean by "he looks awful"? He looks really young to me

    • @grubbybum3614
      @grubbybum3614 4 роки тому +3

      @Jim Jimmy I'm pretty sure this guy said he doesn't use Botox or implants, in the previous podcast.

    • @michaeldalton7611
      @michaeldalton7611 4 роки тому +19

      Peter Lustig How is he a fraud? Why are you so hateful?

  • @elandashing1814
    @elandashing1814 4 роки тому +43

    David Sinclair - The Male Rhonda Patrick
    It's rare a top scientist is so easy-going and fun (even funny) - Pleasurable 2nd Podcast

    • @ryanh.2866
      @ryanh.2866 4 роки тому +1

      Elan Dashing Rhonda Patrick isn’t a top scientist

    • @roryrory20
      @roryrory20 4 роки тому +3

      Thats an aussie for ya bro ;)

    • @ichoozjc
      @ichoozjc 4 роки тому +1

      Definitely made up for that NDT podcast. Amirite?

    • @rustic35
      @rustic35 4 роки тому

      Scientists are humans too and most have a sense of humor.

    • @roryrory20
      @roryrory20 4 роки тому

      @@rustic35 omg mind blown 😮

  • @bridgetteferrante268
    @bridgetteferrante268 4 роки тому +12

    Just ordered the book from Amazon! Can’t wait to read it!

    • @shanemack06
      @shanemack06 4 роки тому

      how was it? anything interesting??

  • @bigteddyize
    @bigteddyize 4 роки тому

    You are both great guys, thank you for improve our lives.

  • @frankiecal3186
    @frankiecal3186 4 роки тому +11

    David "Hit it hard and then let it recover" Sinclair....that's what she said.

  • @toolegittoquit789
    @toolegittoquit789 4 роки тому +30

    David kinda looks like Gail the Snail from It’s Always Sunny

  • @adamc9771
    @adamc9771 4 роки тому

    the last 20 minutes are absolutely mind blowing

  • @singingwater69
    @singingwater69 4 роки тому +2

    Joe is smart to talk about the dangers of statins. It was discovered that the statins( first lovastatin then prevasatin) I was taking had done muscular damage. To this day, I have had unexplained hip pain at night while trying to sleep. I don't have arthritus or other health problems that may have caused this pain. That was at least 5 years ago. It turns out to be class action suits involving statins, but I didn't find out about this until it was too late to become part of lawsuit.

  • @DREAMSLEEPMeditationRelaxSleep
    @DREAMSLEEPMeditationRelaxSleep 4 роки тому +40

    amazing. In 20 years David will be Professor X controlling the mutants

  • @timkiebzak6735
    @timkiebzak6735 4 роки тому +294

    I just wanna see joe rogan off a strong edible, sitting and staring at the chimp enclosure for hours, weeping

  • @drewstoltz7885
    @drewstoltz7885 4 роки тому +1

    Another great podcast! Thank you! Bring on more scientists!

  • @YesheRabsal
    @YesheRabsal 4 роки тому +1

    Hey Joe, When Y'all look stuff up during interviews; do you maintain a page with links to all that stuff? Often looking to read deeper here. Love the show. - Also Joe

    • @douglasmschwartz1402
      @douglasmschwartz1402 4 роки тому

      GOOGLE

    • @YesheRabsal
      @YesheRabsal 4 роки тому

      So damn smart! Why didn't my dumb ass think of that. Your parents must be so proud.

  • @ericschinn
    @ericschinn 4 роки тому +26

    Joe “How’s That Coffee” Rogan