Microtubules | Cells | MCAT | Khan Academy

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  • Опубліковано 12 чер 2024
  • Created by Efrat Bruck.
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КОМЕНТАРІ • 144

  • @guguwf1991
    @guguwf1991 8 років тому +174

    I learned more in 13 minutes of your video than in 2 weeks of class, thank you very much!

    • @thibauteloy6841
      @thibauteloy6841 2 місяці тому

      maybe because you were playing to candy crush instead of listenning the teacher ? ( I am joking)

  • @Santa1936
    @Santa1936 7 років тому +249

    Can be taken OOf. I love the accent

  • @carolinegreen4771
    @carolinegreen4771 7 років тому +111

    Microtubule is a much more complex molecule. The building block of this protein is a dimer called tubulin, which is composed of two sub units: α-tubulin and β-tubulin. α-tubulin and β- tubulin form a filamentous chain called “protofilament”. Microtubules are built by arranging 13 such protofilaments around an empty core. This gives rise to a tube-like construction (hence the name microtubule), which is stiffer, longer and wider than actin. Microtubules have a distinct organizing site called the “centrosome”. Microtubule polymerization begins at this organelle. The end where faster polymerization occurs is called the plus terminus. The end where slower polymerization takes place is called the minus end. Microtubules grow from the centrosome towards the membrane, by anchoring their minus end to the organelle. Once microtubules reach the membrane they detach from the centrosome and create a highly dynamic network. The formation of this network is assisted by a group of proteins with microtubule binding domains called Microtubule Associated Proteins (MAP).
    -Creative BioMart

    • @um1569
      @um1569 6 років тому +9

      That's exactly the kind of information I was looking for in this video, nonetheless it was a fantastic video, gave me more info than my professors did lol

    • @nilanjanadani5629
      @nilanjanadani5629 5 років тому +4

      Hey! May I know at what standard are you studying these Microtubules and stuffs? And from which country are you studying?😁

    • @hafsahjan4107
      @hafsahjan4107 4 роки тому

      great...thankuu soo much...this helped me a lot.....stay blessed

    • @virupannamedikinal
      @virupannamedikinal Рік тому

      Thanks

  • @betb48
    @betb48 6 років тому +2

    Wish i had a teacher like you at highschool...very well explained....

  • @kevinbennett5226
    @kevinbennett5226 9 років тому +29

    You sound like you grew up in New York but now live in Canada

  • @ChildishDicaprio
    @ChildishDicaprio 3 роки тому +5

    All I got from this video was “OOOF” lol cool accent

  • @AvParreira
    @AvParreira 8 років тому +3

    A great presentation that takes a very dry textbook concept and makes is simple to understand and grasp.

  • @briansalkas349
    @briansalkas349 6 років тому +20

    Error at 3:13, centrosomes do not duplicate during mitosis, they duplicate during the S phase.

    • @harshinidavuluri878
      @harshinidavuluri878 5 років тому

      You 're right!

    • @lukehoising6401
      @lukehoising6401 4 роки тому +2

      it duplicates in G2

    • @sakshamsingss
      @sakshamsingss 3 роки тому +1

      DNA duplicate in s phase not centrosome

    • @heebz6805
      @heebz6805 2 роки тому

      @@lukehoising6401 S phase of interphase along with DNA not during G2, microtubules are made during G2

  • @pragyasharma8238
    @pragyasharma8238 2 роки тому +1

    understood all the basic concepts .. cleared my head with all the doubts by watching your video..thank u !!

  • @guyseavey6634
    @guyseavey6634 8 років тому +1

    Very well presented. It is very helpful when so many details are presented in a way that is easy to retain. Thank you for a great video lesson.

  • @manuelblank8072
    @manuelblank8072 8 років тому +25

    Correct me if I'm wrong, but aren't interpolar microtubules the ones that do not attache to kinetochores, but go from one MTOC directly to the other?

    • @MrFreakj
      @MrFreakj 4 роки тому +5

      Interpolar microtubules are connected to the interpolar microtubules of the other MTOC. Kinetochor microtubulues bind the kinetochors. So I learned it that way, too.

  • @colife5486
    @colife5486 7 років тому

    wow- one of the best Khan Academy videos I've watched. thank you so much!

  • @user-xp5or3fg9b
    @user-xp5or3fg9b 7 років тому

    now i understand the paclitaxol and the other taxols mechanism of action thank you so much

  • @johnvandenberg8883
    @johnvandenberg8883 7 років тому +6

    Great work Efrat! New York accent? I love it how you say "beezlebaddies"

  • @leahgrausam5368
    @leahgrausam5368 5 років тому +1

    This is a phenomenal video! Well done! Thank you so much!1

  • @kiranakhtar7788
    @kiranakhtar7788 3 роки тому +1

    Time saving explanation... thank you so much

  • @doanviettrung
    @doanviettrung 9 років тому +2

    This teacher makes everything so clear. Anyone knows her channel, please? I want to subscribe.

  • @erikak6450
    @erikak6450 2 роки тому

    I learned about microtubules AND Canadian accents today. Thank you!

  • @tkal123
    @tkal123 9 років тому

    This is a very helpful video of an otherwise very confusing subject. Thanks

  • @zannatul23
    @zannatul23 7 років тому

    thank you efrat, its really helpful x

  • @ingaa.
    @ingaa. 8 років тому

    Thank you so much, this video helped me a lot for a presentation!

  • @sowmiyasubramani1323
    @sowmiyasubramani1323 3 роки тому

    Clear accent , and explaining ,, choose this kind of people to explain the session

  • @TadFishy
    @TadFishy 7 років тому +43

    There is a mistake in your video. Interpolar microtubules are antiparallel microtubules that originate from opposite poles, and overlap at the midzone of mitotic spindles. They don't attach to kinetochores. The ones you showed are kinetochore microtubules. Would be good to make it clear that there 3 types of microtubules taking part during mitosis and they all have different functions.

  • @farihaakhter3946
    @farihaakhter3946 2 роки тому

    This vedio is very helpful for all of us who want to know more about microtubules very descriptively or elaborately...

  • @FatimahWaleed
    @FatimahWaleed 9 років тому

    It is very clear 💗 thank you so much.

  • @rawda2167
    @rawda2167 Рік тому

    Thanks it helps me a lot !!!!

  • @johntindell9591
    @johntindell9591 7 років тому +2

    great work

  • @russelmiller7311
    @russelmiller7311 7 років тому +1

    Both the mitotic spindle and the interphase cytoskeleton are formed from rapidly tuning-over microtubule populations with half lives of less than a few minutes, which grow from and shrink towards the microtubule organizing centres.

  • @pinkfrosting0
    @pinkfrosting0 6 років тому +20

    Love the jersey accent. Great video :)

  • @Tante90Emma
    @Tante90Emma 4 роки тому

    One of the best khanvideo I have ever seen.

  • @merlinmystique
    @merlinmystique 4 роки тому

    you are great at teaching, thank you

  • @Skurkey
    @Skurkey 8 років тому +4

    Very clear and well presented. Thank you for your time and talent.

  • @redshark618
    @redshark618 9 місяців тому +1

    I dont know if her accent is NYC or NJ, but I love it

  • @annikas2225
    @annikas2225 7 років тому +1

    This is so helpful for my AP Bio test!!! Thank you!!!

  • @comfortkaimbo3
    @comfortkaimbo3 7 років тому

    this was a good job well done

  • @ahmadaamir7684
    @ahmadaamir7684 8 років тому

    Extremely helpful

  • @zannatul23
    @zannatul23 7 років тому

    thank you, you are a lifesaver

  • @guynouri
    @guynouri 3 роки тому

    Excellent clear clearest yet

  • @Twoplusfouris7
    @Twoplusfouris7 9 років тому

    Great job!

  • @misssweethearted
    @misssweethearted 8 років тому

    this was actually pretty good

  • @khamikos1
    @khamikos1 7 років тому

    perfect.thanks

  • @virupannamedikinal
    @virupannamedikinal Рік тому +1

    Thank you so much.

  • @yiiyatschan1395
    @yiiyatschan1395 3 роки тому

    Thank you for this video.

  • @ntethelelocilo3728
    @ntethelelocilo3728 5 років тому

    ngithande nje izwi lakho ntokazi yomngisi....i learnt a lot from this video, thanks!

  • @wardhammoud
    @wardhammoud 7 років тому

    Much appreciated

  • @krisanthonysilveira8244
    @krisanthonysilveira8244 8 років тому +2

    Just a small correction doesnt the microtubule arise from the pericentriolar material rather then then centriole ??

  • @jaquesfrancais3030
    @jaquesfrancais3030 5 років тому +1

    9:19 I think there is something incorrect, in the 9+2 arrangement of the basal body the central microtubules are NOT paired as the other ones (1 complete and 1 incomplete microtubule, who attach each other). Indeed, the central "pair" is more like TWO SEPERATE and both complete microtubules, just connected by a bridge and not direcly attaching, as your drawing suggests. Pls correct me if I'm wrong.

  • @TheSharkSoul
    @TheSharkSoul 9 років тому

    I'm so grateful for this!

  • @LeaBrigitteMagret
    @LeaBrigitteMagret Рік тому

    Thank you so much!

  • @ayaabdi9141
    @ayaabdi9141 8 років тому

    thank you..

  • @himalaydebsourav
    @himalaydebsourav 3 роки тому

    An excellent class.

  • @sudiptasahaniloy976
    @sudiptasahaniloy976 8 років тому

    thank u so much buddy..... :)

  • @user-xu8pt6uy8h
    @user-xu8pt6uy8h 2 роки тому

    You are great.

  • @ayoadeodebode4405
    @ayoadeodebode4405 Рік тому

    Great illustration. I must point out that the centromere and kinetochore lead the motion, not the arm of the chromatids as illustrated.

  • @BrandonSLockey
    @BrandonSLockey 5 років тому +1

    why are there no more detailed videos on this :(

  • @AvocaSingleTrack
    @AvocaSingleTrack 6 років тому +10

    Brooklyn ? Queens ?? ...haha

  • @mr.anti-islam7313
    @mr.anti-islam7313 2 роки тому

    Thank you

  • @rangineechoudhury3755
    @rangineechoudhury3755 2 роки тому

    Well explained.

  • @slehar
    @slehar 3 роки тому

    Wow!!!

  • @hamidizouina4787
    @hamidizouina4787 7 років тому

    plzzz what aplication do you use ???

  • @nikiene5764
    @nikiene5764 5 років тому +1

    There is a mistake in your video. The 'interpolar' microtubules in the video are actually kinetochore microtubules. The interpolar microtubules extend from opposite poles and meet each other somewhere around the center where they overlap and associate with motor proteins.

  • @matthewlee4834
    @matthewlee4834 7 років тому +2

    I liked her accent, but it took a while for me to understand when she was saying "anchoring" at 4:09 xD

  • @tanishagavali5171
    @tanishagavali5171 4 роки тому

    This was so good.

  • @shikhakashyap5591
    @shikhakashyap5591 4 роки тому

    I just loved this video😍😍😭😭

  • @angelavolkov1126
    @angelavolkov1126 Рік тому

    Neat :)

  • @angelavolkov1126
    @angelavolkov1126 Рік тому

    Can also grow by branching, not just linearly

  • @npacknoski
    @npacknoski 7 років тому

    does this come up on the grade 12 course or biology 30? im in process of needed to redo mine dont wanna waste my time learning it, if i dont need to

  • @foadazizpur7442
    @foadazizpur7442 8 років тому +1

    URGENCY QUESTION: in the fungi, how chromosoms move in their nucleuses?
    does the strips of duke transformed from cytoplasm to nucleus?

  • @Ngonyen401
    @Ngonyen401 2 роки тому

    Thanks a lot..i pass the test because of your video 🤧🤧
    Got 15/16 🤗

  • @normadicn5700
    @normadicn5700 4 роки тому

    Lovely accent. 🤩

  • @ThePassportPapi
    @ThePassportPapi 7 років тому

    bring back khan!

  • @Petrov3434
    @Petrov3434 4 роки тому

    Kudos to Lynn Margulis

  • @meeha7604
    @meeha7604 9 років тому

    How do u spell dionene correct way and what would happen of some consumes more then that is required by the body and where is it devised from plants or animal what is the structure of it compound element ?
    What would happen if tubular over grow do that me brain mass grows

  • @niloufarm.n6330
    @niloufarm.n6330 4 роки тому

    What's this app u use for drawing?

  • @Shimulnath96
    @Shimulnath96 4 роки тому

    Let me clear,, During synthesis phase(a phase of interphases) do the whole centrosome become double or only centriole become double?

  • @oraclebjj
    @oraclebjj 7 років тому

    Reminded me of school again. Lots of labelling of parts less actual explaining of how stuff actually works. Are those tubules in the neuron as she calls them "tracks" transporting electrical signals? Or something else.

    • @lovelytangcalagan9264
      @lovelytangcalagan9264 7 років тому +1

      kimura kano No electrical signals aren't "transported" and the tracks that she showed are within the cell. The actual electrical signals that neurons transmit are passed in its plasma membrane through a complex process involving ion channels.

  • @user-xb7vt7pk7l
    @user-xb7vt7pk7l 3 роки тому

    That's a lot of protein names to remember

  • @peculiarezindu1043
    @peculiarezindu1043 5 років тому

    Tnx for the teaching but signals did not go back they go forward from d dendrite to the axon terminal and then d axon terminal takes received signal to another neuron and so on continuously,,,,tnx again ma'am

  • @user-sj8es7jh7r
    @user-sj8es7jh7r 17 днів тому

    very good video if u are student who got exam 2 days after

    • @enacausmembrane
      @enacausmembrane 10 днів тому

      we actually say "2 days from now". The Word "After", makes it seem like you are studying after the exam has already ended.

  • @shizzassimplesciencesss5590
    @shizzassimplesciencesss5590 6 років тому

    Coool, I never liked khan's but this lady overwhelm me, keep it up miss unknown u r doing great

  • @rehanahamid4328
    @rehanahamid4328 3 роки тому

    Centrosome is absent in plants....how spindle fibers are formed in them

  • @chrisjernigan1912
    @chrisjernigan1912 3 роки тому

    Shouldn't it be cawled the 9 +1 arrangement?

  • @MikeyIV
    @MikeyIV 7 років тому

    How do most cells transport vesicles? Just in the cytosol, no railroads? Also what holds the organelles of a cell (nucleus ER, etc) in place? Is that microtubules?

    • @yashikaraghuwanshi7634
      @yashikaraghuwanshi7634 7 років тому +1

      Intermediate filaments hold the cell together I think, and the railroads you talk about, are microfilaments.

  • @swerasharma5218
    @swerasharma5218 10 місяців тому

    slay video

  • @tomasmieger6826
    @tomasmieger6826 3 роки тому

    Amazing stuff - Thx.

  • @TheFr3styler
    @TheFr3styler 6 років тому +1

    I thought Centrosome wasn't an organelle? 2:12

  • @sajidaiqbal3688
    @sajidaiqbal3688 6 років тому +1

    isnt it kinetOchore

  • @Max-vi9is
    @Max-vi9is Рік тому +1

    Anyone here to understand orchestrated objective reduction?

  • @Andrew-kh7rz
    @Andrew-kh7rz 5 років тому

    Is astonishing how much information is wrong on this internet

  • @williamaderera3371
    @williamaderera3371 5 років тому

    waht is kinetichore ,i didn't get it

  • @benashley2955
    @benashley2955 7 років тому

    if microtubules are dynamic then how is their structure studied

  • @ellastewart8122
    @ellastewart8122 2 роки тому

    kind of vague.i still dint get the main functios of microtubules

  • @madisonmarano2171
    @madisonmarano2171 2 роки тому

    you must be from Jersey with that accent !!!

  • @guynouri
    @guynouri 3 роки тому

    Fast and furious

  • @FishoeShoe_da_great
    @FishoeShoe_da_great 5 років тому

    5:06 is this inside a cell or a nucleus?

  • @sushritbisht7863
    @sushritbisht7863 5 років тому

    This girl’s from Brooklyn!?

  • @godhelpme8977
    @godhelpme8977 3 роки тому

    Cilia and flagella 9 + 2
    Centriole 9 + 0

  • @jamesfilosa6277
    @jamesfilosa6277 8 років тому +1

    Great!! Thank you!! One correction: kinetOchore* (it's spelt with O, not I) :S

  • @notlarry6689
    @notlarry6689 6 років тому

    kinetochore is spelt wrong, she spelt it with an i rather than an o

  • @robertogalletti1182
    @robertogalletti1182 3 роки тому

    Since when does Harley Quinn teach a microbiology class?