Immunology Lecture 16 - Type IV Hypersensitivity Reactions
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- Опубліковано 8 лис 2013
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This lecture covers T cell-mediated delayed hypersensitivity reaction (Type IV). Sensitized T cells release cytokines that activate macrophages and act as chemotactic agents for inflammatory cells. Issues like Type I Diabetes Mellitus, Multiple Sclerosis, Guillain Barre Syndrome, Hashimoto's thyroiditis, Graft vs host, contact dermatitis and PPD are talked about. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Immunology Video: Hypersensitivity Type IV
ua-cam.com/video/TJM-lBc9rWU/v-deo.html
This is the best video regarding type 4 hypersensitivity! Thank you!
Fantastic!!!! Thank u n God Bless u n ur loved ones. 👏👏👏
thank you dr and i hope my presentation on type four will go better you really sacrifice.you are hero
most clear concept.. make very nice......thanks sir
Thank you. Helpful and quite in deapth.
You sir, are an excellent educator.
Amazing Dr Mobeen
thankyou so much. god bless you!!
You are just amazing thank you so much god bless you
Thank you and God Bless
Mind blowing..It is Very helpfull lecture
thanks a lot ... it was helpfull
Dr. Syed, thank you for the helpful video! Just an aside, your handwriting is beautiful.
Very nice teaching sir thanku very much keep it up god work for students
Thank you Sir...it was super
Bokan sb: you are correct MS affects white matter of the CNS. These are Oligodendrocytes.
Superb sir nice explaination
Thank you sir🥰🥰😊
Marvellous job sir ! Respect
Thank you. Find more lectures on drbeen.com.
Thanks drbeen, very good explanation
Pleasure. Check drbeen.com for more lectures.
vwziful - could not reply to your post. Something with this new commenting system prevents me from replying to your post. Hope you can read this comment: I am talking about the blistering due to contact with chemical substances or plants.
Awesome! Thank you.
You are welcome!
Thank you Dr. Mobeen
You are welcome!
Sir, please make a complete details video on 'polyclonal and monoclonal antibody "for exam. All this video on ' hypersensitivity reaction' helps me a lot. Thanks to you for this.
very clear. thank u so much.
aditya malladi you are welcome!
thank you so much . you are really great doctor
Thank you!
Very interesting teaching thank you so much, have u made any video on Serology tests?
Not yet.
seriously u teach in the best way..😊 thanks alote for the video
Good to know. There are more lectures to keep you happy. Visit: www.drbeen.com/catalog
Glad that you like our teaching. Please find more videos on www.drbeen.com/catalog
Best
Mobeen
Thank you very much u are indeed great
You are most welcome. Study well and continue being the best! Check drbeen.com for more lectures.
Very very informative and knowledgeable
Thank you!
Will you plz upload type 2 hyper sensitivity?
very very well structured! i really enjoyed it!
have you ever considered doing more pathophys / pharma? ;)
Thanku much Sir for hypersensitivity lectures.. these helped alot .. thanku once again
My pleasure. Check out drbeen.com for more lectures.
hi, was just wondering if B cells would be involved in any aspect of this immune reaction? I understand that antibodies are not produced but do the B cells act in any other ways?
Sir,
Please upload a lecture on coagulation cascade and coagulation tests integrated within.
Thank you Sir.
Expecting a positive response.
Sir,which one is for T Cell-mediated Cellular Immunity?
guillean barre is a type 2 hypersensitivity due to antigenic similiaruty to camplobacter.
Thank you very much doctor mobeen ., please is there a video about hypersensitivite type 1 and 2 !!!?
+imane amy yes. Check in the videos or visit drbeen.com and go to immunology module (it is free). There you will find all videos in a list.
In Type 1 DM and MS,
can i say that the lymphoctes are sensitised in the first exposure to the islet of langerhans or schwanna cells. then they become memory lymphocytes and they just attack these cells again? So does this mean that memory lymphocytes can straight bind to the antigen and does not need any help from APC?
Tq
Is der any specific pathogen for multiple sclerosis? like for tuberculosis myobacterium wich goes into the body n causes this reaction
Where do you find the informations? in which book can i find it ??
superb
Thanks
Sir ,,,make a video about type2 hypersensitivity pls
MS = demyelination of oligodendrocytes
GBS = demyelination of schwann cells
I really gone fan of u sir
Thank you, dear. Study well.
thank u so much sir...can u plz upload hypersensitivity 2 lecture as well :)
+aakash sharma will do!
but blistering in pemphigoid vulgaris and bullous phemphigus is type 2??
hello dr saab..i have a query in delayed hyper sensitivity reaction when cd4 is activated by antigen presenting cells (like in case of tuberculin test) they became sensitive and wait for the antigen to re enter the body. why they don't follow the tradianal path like garbbing the tuberculin molecule presenting the antigen to b cells and provoke a humoral response instead of cell mediated and damaging the tissue by casies necros?
and thank you for your contributions
+Sulaiman Gran it is not that the cells will only work through one pathway. It is the predominance of the result. All mechanisms that can engage in a given situation do become engaged. Some are more effective than others.
which type of auto immune disease does crohn's disease come under?
sir, type 1 diabetes is disease which is due to type 4 hypersensitivity section- intracellular pathogenic antigen where macrophage activates T1cell which in turn activates macrophage by IL12 and IFN gamma cycle and cause damage to tissue. ok but what is the pathogen here?
No pathogen is involved for type 1 DM.
Thank you, the lecture was laid out in a very organized manner and was very inclusive. The camera man could take a little less artistic license.
Thank you for your comments Eric Watkins. I enjoyed the camera man's license thought from you :-)
same with candida test ri8
Dr what about costimulus for Cytotoxic T cell activation in Contact Dermatitis?
Can killer T cell function properly without co-stimulus Il-2 ???
Co stimuli is not needed for killing function, it is only required to activate CD8+ T cell
He is actually talking about memory cytotoxic t cell in skin formed after primary exposure the work in kind of same way as memory B cells they also don't need costimulation for activation
warthins tumour is also a type 4 reaction
diabete II is hypersensivity ??
No. Diabetes Mellitus type I is.
I'm getting distracted by the cameraman moving too much, still a nice lecture
Please tell the camera man to stop moving around too much!!!! my head is spinning goshhhhhh
Tq