Hy Emily , l made my injection ,with nordimed metotrexate, it was ok,it s easy but when l remove the injection ,l mean the needle ,a little bit of the liquid went out ,it is ok? My MTX it is not a pen .Thank you.
The advice I've had for spillages is to wipe with a tissue then rinse with plenty of water, disposing of the tissue in a clinical waste bin so that the liquid doesn't come into contact with anything else. Was it ok?
Despite being told what to do I was still nervous, and your video has made me absolutely chilled about doing it for the first time. And it was super easy. Thanks for recording it x
I wasn't scared at all (in fact, I was somewhat excited), but now that I'm about to do it (even after watching the video), I'm terrified... 🙈 I've had quite a large fear of needles before, but that's mostly gone now but I'm still scared sometimes, haha (for example, blood tests don't scare me at all and this is probably even less painful than that)...
Thanks for leaving a message! How are you feeling now? Have you managed to do the first one, or isn't it time yet? I've spoken to loads of people who were really nervous the first time, it's natural, but they've tended to feel a lot better after getting that first one out of the way. I hope you're doing ok.
@@aslightlyatypicalpresentation Hi, sorry for not responding, I didn't get a notification, since it wasn't a direct reply to me (and thanks for responding)! I just did my second one (my mom did it last time, now I had to do it myself)! Last time it hurt quite a bit afterward (pretty sure it was due to the medication), but this time there was only a slight funny feeling afterward (no pain). And it was very easy to do myself the second time! So no worries, I'm sure I won't even be scared of it from now on! 😁👍
@I Hate Myself I'm so sorry you didn't get a notification, hopefully this one comes through. So happy to hear how much easier it was the second time around for you! Long may that continue :)
The ease of which you took your dose was really reassuring and rubbed off on me. I had been super nervous but felt so much better after watching your video. Now just fingers crossed that the side effects aren't too bad!
Going to start injections as soon as they are filled by my pharmacy. They say there is a national shortage, making it more difficult to fill. Your video helped relieved a lot of anxiety I had about giving myself injections, and I’m a nurse! Hope you are doing well. Wish me luck!
Thank you so much for watching! Here's the instruction booklet with the diagram I was using: metoject.co.uk/app/uploads/2022/09/metoject-adult-admin-guidelines.pdf
Thank you for sharing the video. I'll be starting mine on Monday and your vid. Give me confidence to Inject my first dose... thank you. Watching from UK 🇬🇧
Thanks very much for sharing this with us…. I’ve been taking Sulfasalazine tablets but my mouth inside is really sore, so I’ve been advised by rheumatology to stop meds and they’ll be in touch in a few weeks to discuss using methotrexate by pen. You’ve reassured me that it’s neither difficult or painful. Thank you!
Thank you so much for your message! I'm so happy to hear that the video offered some reassurance about the injection pens, they really have been easy to use from the start - and I hope the switch to methotrexate works well for you.
Giving me courage.. I was diagnosed with Systemic Lupus & previously given Methotrexate tablets which had side effects for me. Now they given me Injection pens. Today will be my first go at it. 20mg dose, and so I have been looking online to remind myself how to use it, and get up some courage, as a bit nervous about any side effects. Sure your video will help encourage me to go for it.
I hope your first injection goes smoothly for you, Richard. Good luck! I've heard a lot of people say they find the side effects are fewer with the injections and I hope that proves to be the case for you too.
Thanks for your message Susan, I'm so glad you're feeling better. It's quite a thing to start injecting medication but it's honestly never hurt. Crossing my fingers for you too.
Hi thank you for uploading this video I’m starting my injection very soon so your information shared was very helpful and has eased my nerves I have fibromyalgia and pcrosotic rA
I'm so glad the video was helpful, thank you for your message! My doctor thought I might have PsA too at first, so I know the symptoms can be quite similar. I really hope the injections are effective for you.
My nurse and pharmacist say a 45°. But it's not a pen like you have. I actually have to draw it out then inject. I'd rather have the pre-loaded pen like you have. I have been on the pills for about 4 months. A sarcoidosis specialist is switching me from pills to injection. 25mg a week. Appreciate the video. Hope you're feeling better!
Hi, thank you so much for your message and kind words! Yes, I think the technique is different for injections with a syringe versus the pre-loaded pens. Gradually it does seem to be having a helpful effect on my symptoms so I'm glad to have tried it. I really hope the switch to injections works out well for you too.
Hi I watched this and decided to have the injections instead of the tablets as they made me feel so ill. You explained it really well, it gave me the confidence to go ahead and it is as easy as you have shown. Just wanted to thank you. I forgot to ask the nurse if you still need to take the folic acid and wondered if you are taking it 😊
Hi Jay, thanks for your kind comment, that made my day! I'm so glad you found the video helpful. I do still take the folic acid, same dose as with the tablets. From what I've heard a lot of people find the side effects milder with injections, so I really hope that's the case for you too.
Thank you - you too :). As far as I know the purpose of the folic acid is just to help with mtx side effects, so if you find those improve with the injections you could always chat to your medical team about reducing them if you'd rather not have them. Must admit I haven't tried it myself so far but taking less medication would be good!
Also it is recommended that you don’t take folic acid on the day you have your injection. You can take it the following day. Also you can research this or ask your doctor but if you have a one or two MTHFR gene variants you might have to take a methyl folate so it can be absorbed. One gene variant means a 40% chance of not bringing able to absorb and two genes is more like 80% you can’t absorb folic acid . If you have done 23 & Me you can check the data for these variants. As always do your research with legitimate peer reviewed publications and ask qualified professionals if any of this is relevant to you.
I’m going to be requesting methotrexate as an injection as I’m struggling with the oral medication, even at 12.5mg. Weekly bouts of vomiting are not great.
Sorry to hear that, that sounds really rough. I definitely found the side effects improved when I switched to injections so I hope they help for you too.
@ Ahh brilliant, I’m so glad it worked out for you. Did the higher dose from the injection help manage your symptoms? I realise this video is a few years old now.
I actually stayed on the same dose as with the tablets (25mg weekly), but some say you get a higher effective dose with the injections because they're a more direct route - tablets have to go through the digestive system before taking effect. I think that was the case for me (and am still on the same dose). So you might find you get more therapeutic benefits from the injections as well as hopefully fewer side effects. Have my fingers crossed for you!
I’m so scared of that button l, I know is doesn’t hurt I know the needle is tiny. But I never knew I had a fear like this o get bloods done all the time and just not bothered. But I can’t seam go press the button out of fear
I totally understand, this condition throws up so many new things to deal with doesn't it. New treatments being a big one! If this isn't something you would usually feel anxious about it, would it be possible to try just doing it without thinking about it? That might help to confirm what you already know, that the needle is very small and it doesn't hurt. Once you've done it one time, the next time may feel better. Or could you get some help from a nurse or friend/family member? I know lots of people find it helps to have some support with injections at first. I really hope you find something that helps with this ♡
Hello Emily, I am currently collecting research on the journey of people using autoinjector for rheumatoid arthritis and trying to gather insight on different people's experiences and their emotions throughout the process with them. Would you be open to talking about your experiences with your autoinjector?
Hi Cydney, thanks for reaching out. That sounds like an interesting project. Could you tell me a little more about the research you're doing and what would be involved please?
Thank you! I hope you're doing ok, and with that first solo injection under your belt. I'm finding MTX ok, it does help with symptoms though took a while to take effect initially - and am definitely better with the injections than tablets.
Thanks for sharing. I used this for the first time yesterday. Have you had any issues with side effects being more pronounced with the pen than the tablets. I’ve not been well at all today, which is usual after taking Methotrexate. BTW, a nurse mentioned to me that showering before using injectiors or PFS, can help minimise injection site infection. I also take Stelara PFS, every 8 weeks. So the methojet is easy to use. If squeamish you could get a friend or someone to push the button… it doesn’t hurt👍
Thanks so much for your message Eoin. I did have an increase in some side effects when I switched to the pen actually (which was not the plan!) - wooziness and queasiness which I hadn't really had with the tablets, and the cognitive effects lasted an extra day or so although were possibly slightly milder. Its a few months down the line now and they have all decreased, so hopefully they will for you too. As I understand it the injections are effectively a dose increase from tablets because more methotrexate is absorbed that way, so I guess there can be a period of adjustment. Thanks for the tip re showering too, appreciated!
That sounds rough, has the injection pen or mechanism changed at all? I occasionally get a little bruising if I get a blood vessel by mistake, but it's been pretty minor so far. Do you have a rheumatology helpline or nurse who might be able to help or advise?
Thank you for this. Starting a 15mg for 2 weeks .. Then 20mg injections.. I have scleroderma and Polymyositis.. I'm nervous and scared about the side effect but mostly doing the injections..hiw are you doing now?!
Hi, thanks so much for your message! I started the same way as you with MTX (although with tablets at that point) - 20mg for a few weeks and then moving up to 25mg. I think that starting with a slightly lower dose gave my body a chance to get used to it and helped with side effects. Are you prescribed folic acid as well, as that also helps. The injections were quite a thing to get my head around at first! But honestly I've found them straightforward in practice and haven't had any problems since that very first one in the video. It definitely helps my RA symptoms. I really hope the injections go okay for you and you see benefits for managing your health conditions too. Fingers crossed for you ♡
Only reason for starting there was plenty of padding at the sides! Thought it might help. I actually mostly inject into the belly area these days, which I was hesitant to do at first but actually find it easier. Sorry to hear it's so sore for you :(
Thanks for your message! Yes, the methotrexate is still an important part of my treatment, and I still take the same dose as in this video. Since then, I've added a third anti-rheumatic medication, sulfasalazine, which also helped. My RA symptoms have improved a lot since then, but do still affect me. Maybe I should do an update video - a lot has happened in the past year!
Hi Carlos, they're both the same medication but the injections are methotrexate in a liquid form that you inject using a pen or syringe, whereas the pills are solid tablets that you swallow with water. In terms of effects, some people find that injections are more effective than tablets at the same dose, because they enter your system directly rather than needing to be digested first, which can reduce the amount of methotrexate that is actually available in the body. Is that the kind of thing you were wondering about? Please let me know if there's anything else and if I can help I will!
Personally I've occasionally had minor bruising at the injection site, but nothing else from the injection itself. It'd be interesting to hear what other people's experiences have been. Did you have anything yourself?
Hello , l was diagnose with RA ,a month ago,l am scared of it, l am on metrotexat ,injections,how long was start working on you,and how are you now,do you have pain and swallow ,l mean l am asking you to share with me your story, l am afraid ,l don t know ,many things without answer, l am from Romania ,excuse my english ,thank you for sharing with us all in this condition.
Hello, thank you so much for your message though I'm sorry to hear that you have this diagnosis too. I found it daunting as well at the start, but it has got much better in time, the shock passes. It took probably about 3 months to start noticing the methotrexate working, and longer for the full benefits to show. It was hard to tell exactly when because I was taking other medications too. I found the injections more effective than tablets. If you've been taking it for a month there is still a good chance of it working more than it is now. Since being diagnosed I've added other medications and things have improved more. I don't have pain like I did at diagnosis, it's very manageable, and I can do so much more now. Everything is far better. It is really hard before the medication starts working properly, but I hope that offers you some reassurance - it really can improve but sometimes takes a while. If you have any other questions I could help with please just ask, always happy to share. Are you taking methotrexate alone or any other medications with it? There are many options for adding more. Keeping my fingers crossed that the methotrexate works well for you, and soon.
@@aslightlyatypicalpresentation Thank you so much, l am takink metrotexate 1.5 mg. Injections by week, next day folic acid by 5 mg, and avery day i take prednison wich is cortizon ,for pain ,l have a knee that hurts and that all for now, l am going to the doctor when l have a month of tratament. I ' ve been diagnoise early february and they say it is the debut of desease,that l have a chanse of a normal life. I am 42 years old.How about you ,you still working and do the things you did before the illness? Thank you so much for you response ,l was a verry sad ,l was afraid of depresion.
I'm sorry to hear how low you've been feeing, it's natural I think with a health condition like this. It can affect everything and there's so much to take in - the effects of RA but also medications, side effects and changes to daily life. It's really good that your doctor has caught the disease early though, lots of people are treated successfully and get back to doing the things they used to. It can take some months, for some people longer, but there are many treatment options and sometimes it's a case of trying a few before you find what works for you. My journey has been quite difficult but I had a very rapid disease onset, and by the time RA was diagnosed many joints were affected and I was very limited in what I could do. That has improved hugely though with treatment. I had to take 4 months off work when it was worst, but I am back at work now - not quite full-time hours yet but 4 days a week - I will get there! I take prednisolone too, it's essentially the same as prednisone, and hydroxychloroquine and sulfasalazine which are RA medications like methotrexate. It really helped me in the first few months to hear about other people's stories and reach out for support from organisations that help people with RA - it can make you feel quite alone when it's so difficult. Do you have support around you, while you adjust to all of this?
@@aslightlyatypicalpresentation Hy ,Emily, yes i have suport ,my husband and my son are very cloused to me, really help, l have only one knee with pain and a little bit the right jaw was painfful but not so bad ,the other knee swallou but not hurting ,now is ok, l have these little bag with liquid on my both knee ,doctor said is sinovia ,but it will go back when the methrotexate will be install ,my hands were paintfull but now they aren t , l just hope that will not go any longer,to other joints, it is a huge help to talk to someone like "us" ,you know what i mean,and about you, you don ' t take MTX anymore,why?thank you for answering me.
Ah, so glad you have your family around you to help and support. Hopefully the MTX will start working very soon, and the prednisone reduces the swelling and pain while it's starting to work. I'm still taking MTX, but added HCQ and SSZ as well - triple therapy, plus prednisolone. Sorry that wasn't so clear! The extra meds definitely make a difference. Always happy to talk, hoping for a good result with the MTX for you x
Been on this medication and another biological since 2012 they did not always use to be this easy, they used to be needle injections standard. Nothing works for me anyway and this makes me sick eberyones doses will be different xx
Yes, I feel lucky that the pre-filled pens are so simple to use though some people prefer the syringes too - I think they're more commonly used in the States than where I live. Sorry to hear the MTX isn't a good med for you, it sounds like you've had a long search for an effective treatment combination. Hoping there are other options you get the chance to try ♡
@@aslightlyatypicalpresentation I've tried all the options this far. And have to see specialists because my body is rejecting all medication. I am a rare and hard case for the doctors. Lol. I can't even look at that box without wanting to throw up, I wish you all best though...xx we all have our own things to deal with re this cruel disease. Hope others can control it better....xx I'm so deformed by it because nothing is helping me. Had all the options you can have. I hope science 🧪 figure out some new things 😁 Look after yourself anyway 🙏
It sounds like RA has brought you more challenges than most have to deal with. So sorry to hear how hard it's proving for you to find some sort of relief. New medications are being developed and approved all the time and I just hope one of them will finally work for you. Wishing you all the best ♡
Hello. I just did my first injection on my own. I hope I did it right. Do I throw away the left over in the valve? It's almost half filled still?? Thanks for your help!!
Thanks for your message! It's great to hear you've got that first one done. I'm not sure why there'd be about half left inside but yes, best to discard it. If you have any concerns maybe you could take a photo of the used injection pen and show your rheumatology nurse or pharmacist next time you see them, just to check it's working ok? It might just be something about that pen.
If I haven't covered everything you'd find it helpful to know about the injection, please just ask!
Hy Emily , l made my injection ,with nordimed metotrexate, it was ok,it s easy but when l remove the injection ,l mean the needle ,a little bit of the liquid went out ,it is ok? My MTX it is not a pen .Thank you.
The advice I've had for spillages is to wipe with a tissue then rinse with plenty of water, disposing of the tissue in a clinical waste bin so that the liquid doesn't come into contact with anything else. Was it ok?
Despite being told what to do I was still nervous, and your video has made me absolutely chilled about doing it for the first time. And it was super easy. Thanks for recording it x
Thanks Geraldine, your comment made my day! It's so lovely to hear that seeing my first attempt helped with yours x
I wasn't scared at all (in fact, I was somewhat excited), but now that I'm about to do it (even after watching the video), I'm terrified... 🙈 I've had quite a large fear of needles before, but that's mostly gone now but I'm still scared sometimes, haha (for example, blood tests don't scare me at all and this is probably even less painful than that)...
Thanks for leaving a message! How are you feeling now? Have you managed to do the first one, or isn't it time yet? I've spoken to loads of people who were really nervous the first time, it's natural, but they've tended to feel a lot better after getting that first one out of the way. I hope you're doing ok.
@@aslightlyatypicalpresentation Hi, sorry for not responding, I didn't get a notification, since it wasn't a direct reply to me (and thanks for responding)! I just did my second one (my mom did it last time, now I had to do it myself)! Last time it hurt quite a bit afterward (pretty sure it was due to the medication), but this time there was only a slight funny feeling afterward (no pain). And it was very easy to do myself the second time! So no worries, I'm sure I won't even be scared of it from now on! 😁👍
@I Hate Myself I'm so sorry you didn't get a notification, hopefully this one comes through. So happy to hear how much easier it was the second time around for you! Long may that continue :)
The ease of which you took your dose was really reassuring and rubbed off on me. I had been super nervous but felt so much better after watching your video. Now just fingers crossed that the side effects aren't too bad!
Thank you for your message, I'm so happy to hear this! Will keep my fingers crossed for little or no side effects for you too!
Going to start injections as soon as they are filled by my pharmacy. They say there is a national shortage, making it more difficult to fill. Your video helped relieved a lot of anxiety I had about giving myself injections, and I’m a nurse! Hope you are doing well. Wish me luck!
Good luck, Tom! You've got this one. And thank you for your kind comments too, they're very appreciated.
Thank you so much! My rheumatologist just started talking to me about this today. Your video really helped me.
Thanks for your message! I'm so glad it helped and really hope it works well for you.
Thank you so much, I’m going to be starting methotrexate injections soon and was dreading them. This makes me feel much better
Thank you for your message, I'm so glad it was helpful. Wishing you all the best for when you get started :)
You did so well .cn you share pic of that sheet plz.. Luckett have the pen form❤
Thank you so much for watching! Here's the instruction booklet with the diagram I was using: metoject.co.uk/app/uploads/2022/09/metoject-adult-admin-guidelines.pdf
Hi Emily ! I hope you’re doing fine and i wish you the best.
Thanks Jimmy!
Thank you so much for this video I was able to fully inject myself without no problems after watching this ,much appreciated x
Thanks for your lovely message! I'm so happy the video was helpful to you and glad to hear your injection went smoothly x
I had my first injection today, thank you for the video it helped my nerves❤
you're so welcome! and thank you for letting me know! :)
Thank you for sharing the video. I'll be starting mine on Monday and your vid. Give me confidence to Inject my first dose... thank you. Watching from UK 🇬🇧
Thanks so much for your kind message, that makes my day. Keeping my fingers crossed for you on Monday - you've got this! ♡
I had my first one today! Thank you for this video ❤
You are so welcome! I hope it went smoothly for you x
Thanks very much for sharing this with us…. I’ve been taking Sulfasalazine tablets but my mouth inside is really sore, so I’ve been advised by rheumatology to stop meds and they’ll be in touch in a few weeks to discuss using methotrexate by pen. You’ve reassured me that it’s neither difficult or painful. Thank you!
Thank you so much for your message! I'm so happy to hear that the video offered some reassurance about the injection pens, they really have been easy to use from the start - and I hope the switch to methotrexate works well for you.
Giving me courage.. I was diagnosed with Systemic Lupus & previously given Methotrexate tablets which had side effects for me. Now they given me Injection pens. Today will be my first go at it. 20mg dose, and so I have been looking online to remind myself how to use it, and get up some courage, as a bit nervous about any side effects. Sure your video will help encourage me to go for it.
I hope your first injection goes smoothly for you, Richard. Good luck! I've heard a lot of people say they find the side effects are fewer with the injections and I hope that proves to be the case for you too.
Thank you. I have to start this week. I feel much better now.
Thanks for your message Susan, I'm so glad you're feeling better. It's quite a thing to start injecting medication but it's honestly never hurt. Crossing my fingers for you too.
Thanks for sharing. First injection today!
Oooh I hope it goes well (or has gone well) for you! And thank you for watching :)
Hi thank you for uploading this video I’m starting my injection very soon so your information shared was very helpful and has eased my nerves I have fibromyalgia and pcrosotic rA
I'm so glad the video was helpful, thank you for your message! My doctor thought I might have PsA too at first, so I know the symptoms can be quite similar. I really hope the injections are effective for you.
Thank you, I am going to do my first injection now. This video has helped 🙂
Ooh I hope it's gone well for you! I'm so glad if the video could help a bit ♡
I hope you are doing well and thanks for sharing this, it was helpful in many ways.
Thank you so much, I'm really glad it was helpful to you.
Very helpful. Due to do my 1st one on Saturday. Thank you
Thank you for watching, I'm so glad it helped. Hope it goes smoothly for you on Saturday :)
My nurse and pharmacist say a 45°. But it's not a pen like you have. I actually have to draw it out then inject. I'd rather have the pre-loaded pen like you have. I have been on the pills for about 4 months. A sarcoidosis specialist is switching me from pills to injection. 25mg a week. Appreciate the video. Hope you're feeling better!
Hi, thank you so much for your message and kind words! Yes, I think the technique is different for injections with a syringe versus the pre-loaded pens. Gradually it does seem to be having a helpful effect on my symptoms so I'm glad to have tried it. I really hope the switch to injections works out well for you too.
Thanks teaching, today I had my first metoject 💉
You're so welcome, I hope it went well for you!
Thank you very much, this really helped to calm my nerves.
Thanks for your kind message, I'm so glad it helped ♡
Hi I watched this and decided to have the injections instead of the tablets as they made me feel so ill. You explained it really well, it gave me the confidence to go ahead and it is as easy as you have shown. Just wanted to thank you. I forgot to ask the nurse if you still need to take the folic acid and wondered if you are taking it 😊
Hi Jay, thanks for your kind comment, that made my day! I'm so glad you found the video helpful. I do still take the folic acid, same dose as with the tablets. From what I've heard a lot of people find the side effects milder with injections, so I really hope that's the case for you too.
Thanks for replying. I’d best still take them then. Good luck with everything 😊
Thank you - you too :). As far as I know the purpose of the folic acid is just to help with mtx side effects, so if you find those improve with the injections you could always chat to your medical team about reducing them if you'd rather not have them. Must admit I haven't tried it myself so far but taking less medication would be good!
Also it is recommended that you don’t take folic acid on the day you have your injection. You can take it the following day. Also you can research this or ask your doctor but if you have a one or two MTHFR gene variants you might have to take a methyl folate so it can be absorbed. One gene variant means a 40% chance of not bringing able to absorb and two genes is more like 80% you can’t absorb folic acid . If you have done 23 & Me you can check the data for these variants. As always do your research with legitimate peer reviewed publications and ask qualified professionals if any of this is relevant to you.
thank you for this!
I’m going to be requesting methotrexate as an injection as I’m struggling with the oral medication, even at 12.5mg. Weekly bouts of vomiting are not great.
Sorry to hear that, that sounds really rough. I definitely found the side effects improved when I switched to injections so I hope they help for you too.
@ Ahh brilliant, I’m so glad it worked out for you. Did the higher dose from the injection help manage your symptoms? I realise this video is a few years old now.
I actually stayed on the same dose as with the tablets (25mg weekly), but some say you get a higher effective dose with the injections because they're a more direct route - tablets have to go through the digestive system before taking effect. I think that was the case for me (and am still on the same dose). So you might find you get more therapeutic benefits from the injections as well as hopefully fewer side effects. Have my fingers crossed for you!
Thank you so much your video was very reassuring and helpful 🥰
You're so welcome, thank you for your lovely message :)
Thanks for sharing big help!
thank you, so happy to hear that!
I’m so scared of that button l, I know is doesn’t hurt I know the needle is tiny. But I never knew I had a fear like this o get bloods done all the time and just not bothered. But I can’t seam go press the button out of fear
I totally understand, this condition throws up so many new things to deal with doesn't it. New treatments being a big one! If this isn't something you would usually feel anxious about it, would it be possible to try just doing it without thinking about it? That might help to confirm what you already know, that the needle is very small and it doesn't hurt. Once you've done it one time, the next time may feel better. Or could you get some help from a nurse or friend/family member? I know lots of people find it helps to have some support with injections at first. I really hope you find something that helps with this ♡
Hello Emily, I am currently collecting research on the journey of people using autoinjector for rheumatoid arthritis and trying to gather insight on different people's experiences and their emotions throughout the process with them. Would you be open to talking about your experiences with your autoinjector?
Hi Cydney, thanks for reaching out. That sounds like an interesting project. Could you tell me a little more about the research you're doing and what would be involved please?
I've been on mtx for my psoriasis but its made my appetite so low that i lost weight
so im gonna ask my dermatologist to get me these instead
That sounds concerning, I do hope you find a medication that suits you better
@@aslightlyatypicalpresentation thanks
Started this last week - first one on my own Monday. How are you finding the MTX? Good video btw
Thank you! I hope you're doing ok, and with that first solo injection under your belt. I'm finding MTX ok, it does help with symptoms though took a while to take effect initially - and am definitely better with the injections than tablets.
Thanks for sharing. I used this for the first time yesterday. Have you had any issues with side effects being more pronounced with the pen than the tablets. I’ve not been well at all today, which is usual after taking Methotrexate. BTW, a nurse mentioned to me that showering before using injectiors or PFS, can help minimise injection site infection. I also take Stelara PFS, every 8 weeks. So the methojet is easy to use. If squeamish you could get a friend or someone to push the button… it doesn’t hurt👍
Thanks so much for your message Eoin. I did have an increase in some side effects when I switched to the pen actually (which was not the plan!) - wooziness and queasiness which I hadn't really had with the tablets, and the cognitive effects lasted an extra day or so although were possibly slightly milder. Its a few months down the line now and they have all decreased, so hopefully they will for you too. As I understand it the injections are effectively a dose increase from tablets because more methotrexate is absorbed that way, so I guess there can be a period of adjustment. Thanks for the tip re showering too, appreciated!
My injection really hurts sometimes. I’ve been using this drug for 2.5 years. Keep getting massive bruises and sore skin. No idea why it’s changed
That sounds rough, has the injection pen or mechanism changed at all? I occasionally get a little bruising if I get a blood vessel by mistake, but it's been pretty minor so far. Do you have a rheumatology helpline or nurse who might be able to help or advise?
Thank you for this. Starting a 15mg for 2 weeks .. Then 20mg injections.. I have scleroderma and Polymyositis.. I'm nervous and scared about the side effect but mostly doing the injections..hiw are you doing now?!
Hi, thanks so much for your message! I started the same way as you with MTX (although with tablets at that point) - 20mg for a few weeks and then moving up to 25mg. I think that starting with a slightly lower dose gave my body a chance to get used to it and helped with side effects. Are you prescribed folic acid as well, as that also helps. The injections were quite a thing to get my head around at first! But honestly I've found them straightforward in practice and haven't had any problems since that very first one in the video. It definitely helps my RA symptoms. I really hope the injections go okay for you and you see benefits for managing your health conditions too. Fingers crossed for you ♡
I inject on the tops of my thighs. What made you go to the sides? I’m just finding it all so sore 😢
Only reason for starting there was plenty of padding at the sides! Thought it might help. I actually mostly inject into the belly area these days, which I was hesitant to do at first but actually find it easier. Sorry to hear it's so sore for you :(
Thanks
Could you tell me please, how do you fill now after 1 years, is this treatment work for you? Is artists improve ?
Do have any side effects?
Thanks for your message! Yes, the methotrexate is still an important part of my treatment, and I still take the same dose as in this video. Since then, I've added a third anti-rheumatic medication, sulfasalazine, which also helped. My RA symptoms have improved a lot since then, but do still affect me. Maybe I should do an update video - a lot has happened in the past year!
good job!
What is the difference between the injection and pill form?
Hi Carlos, they're both the same medication but the injections are methotrexate in a liquid form that you inject using a pen or syringe, whereas the pills are solid tablets that you swallow with water. In terms of effects, some people find that injections are more effective than tablets at the same dose, because they enter your system directly rather than needing to be digested first, which can reduce the amount of methotrexate that is actually available in the body. Is that the kind of thing you were wondering about? Please let me know if there's anything else and if I can help I will!
Para que serve este medicamento
Para mim, é para tratar a artrite reumatóide, mas também pode ser usado para muitas outras doenças autoimunes. (I hope this is a good translation!)
Have anybody had bad side effects from the injection?
Personally I've occasionally had minor bruising at the injection site, but nothing else from the injection itself. It'd be interesting to hear what other people's experiences have been. Did you have anything yourself?
Hello , l was diagnose with RA ,a month ago,l am scared of it, l am on metrotexat ,injections,how long was start working on you,and how are you now,do you have pain and swallow ,l mean l am asking you to share with me your story, l am afraid ,l don t know ,many things without answer, l am from Romania ,excuse my english ,thank you for sharing with us all in this condition.
Hello, thank you so much for your message though I'm sorry to hear that you have this diagnosis too. I found it daunting as well at the start, but it has got much better in time, the shock passes. It took probably about 3 months to start noticing the methotrexate working, and longer for the full benefits to show. It was hard to tell exactly when because I was taking other medications too. I found the injections more effective than tablets. If you've been taking it for a month there is still a good chance of it working more than it is now. Since being diagnosed I've added other medications and things have improved more. I don't have pain like I did at diagnosis, it's very manageable, and I can do so much more now. Everything is far better. It is really hard before the medication starts working properly, but I hope that offers you some reassurance - it really can improve but sometimes takes a while. If you have any other questions I could help with please just ask, always happy to share. Are you taking methotrexate alone or any other medications with it? There are many options for adding more. Keeping my fingers crossed that the methotrexate works well for you, and soon.
@@aslightlyatypicalpresentation
Thank you so much, l am takink metrotexate 1.5 mg. Injections by week, next day folic acid by 5 mg, and avery day i take prednison wich is cortizon ,for pain ,l have a knee that hurts and that all for now, l am going to the doctor when l have a month of tratament. I ' ve been diagnoise early february and they say it is the debut of desease,that l have a chanse of a normal life. I am 42 years old.How about you ,you still working and do the things you did before the illness?
Thank you so much for you response ,l was a verry sad ,l was afraid of depresion.
I'm sorry to hear how low you've been feeing, it's natural I think with a health condition like this. It can affect everything and there's so much to take in - the effects of RA but also medications, side effects and changes to daily life. It's really good that your doctor has caught the disease early though, lots of people are treated successfully and get back to doing the things they used to. It can take some months, for some people longer, but there are many treatment options and sometimes it's a case of trying a few before you find what works for you. My journey has been quite difficult but I had a very rapid disease onset, and by the time RA was diagnosed many joints were affected and I was very limited in what I could do. That has improved hugely though with treatment. I had to take 4 months off work when it was worst, but I am back at work now - not quite full-time hours yet but 4 days a week - I will get there! I take prednisolone too, it's essentially the same as prednisone, and hydroxychloroquine and sulfasalazine which are RA medications like methotrexate. It really helped me in the first few months to hear about other people's stories and reach out for support from organisations that help people with RA - it can make you feel quite alone when it's so difficult. Do you have support around you, while you adjust to all of this?
@@aslightlyatypicalpresentation
Hy ,Emily, yes i have suport ,my husband and my son are very cloused to me, really help, l have only one knee with pain and a little bit the right jaw was painfful but not so bad ,the other knee swallou but not hurting ,now is ok, l have these little bag with liquid on my both knee ,doctor said is sinovia ,but it will go back when the methrotexate will be install ,my hands were paintfull but now they aren t , l just hope that will not go any longer,to other joints, it is a huge help to talk to someone like "us" ,you know what i mean,and about you, you don ' t take MTX anymore,why?thank you for answering me.
Ah, so glad you have your family around you to help and support. Hopefully the MTX will start working very soon, and the prednisone reduces the swelling and pain while it's starting to work. I'm still taking MTX, but added HCQ and SSZ as well - triple therapy, plus prednisolone. Sorry that wasn't so clear! The extra meds definitely make a difference. Always happy to talk, hoping for a good result with the MTX for you x
Been on this medication and another biological since 2012 they did not always use to be this easy, they used to be needle injections standard. Nothing works for me anyway and this makes me sick eberyones doses will be different xx
Yes, I feel lucky that the pre-filled pens are so simple to use though some people prefer the syringes too - I think they're more commonly used in the States than where I live. Sorry to hear the MTX isn't a good med for you, it sounds like you've had a long search for an effective treatment combination. Hoping there are other options you get the chance to try ♡
@@aslightlyatypicalpresentation I've tried all the options this far. And have to see specialists because my body is rejecting all medication. I am a rare and hard case for the doctors. Lol. I can't even look at that box without wanting to throw up, I wish you all best though...xx we all have our own things to deal with re this cruel disease. Hope others can control it better....xx
I'm so deformed by it because nothing is helping me. Had all the options you can have. I hope science 🧪 figure out some new things 😁
Look after yourself anyway 🙏
It sounds like RA has brought you more challenges than most have to deal with. So sorry to hear how hard it's proving for you to find some sort of relief. New medications are being developed and approved all the time and I just hope one of them will finally work for you. Wishing you all the best ♡
@@aslightlyatypicalpresentation thank you x
Hello. I just did my first injection on my own. I hope I did it right. Do I throw away the left over in the valve? It's almost half filled still?? Thanks for your help!!
Thanks for your message! It's great to hear you've got that first one done. I'm not sure why there'd be about half left inside but yes, best to discard it. If you have any concerns maybe you could take a photo of the used injection pen and show your rheumatology nurse or pharmacist next time you see them, just to check it's working ok? It might just be something about that pen.
👍
I jumped
It is quick! Was it ok other than that?
Now it's my turn for the first time, thank you
ahh, good luck!
@@aslightlyatypicalpresentation done it, didn't feel a thing, really didn't expect that. thanks for the video.
that is great, so happy to hear it went so well
Thanks