I absolutely adore the fact that you are so enthusiastic/animated when you instruct these topics. It rejuvenates my motivation to learn and to get excited about material. I think a lot of times students get bogged down in the dryness of material like this (I know I do) when we read it from bland textbooks that just spew out facts. Your enthusiasm when you teach makes me want to absorb the information and have it etched into my brain rather than just memorize it on a superficial level for a test I have in 2 days. Because of you, I see this information as a fascinating topic that I want to remember for years to come that maybe I could just spew out at a trivia game or use to my advantage if a family member is diagnosed with kidney disease. Regardless of my future uses for these facts, I really would like to thank you for putting in the time and effort to not only teach your viewers, but also to inspire us. If only there were more educators out in the world such as yourself. We appreciate you! Keep up the good work
Great video! I have one question though. In this video you're saying that the smooth muscle cells contract in reaction to a HIGH BP, thus lowering the amount of blood that enters the glomerulus. However in your next video about the juxtaglomerular apparatus, you tell us that as a reaction to LOW bloodpressure, the smooth muscle cells also CONTRACT, in order to increase the BP. How would you explain that these two mechanisms of contracting the smooth muscle cells have different reaction (decreasing or increasing BP)?
This is a super important question- thanks for asking. And the answer depends on is WHERE blood pressure changes in relation to the vasoconstriction. In this video, we talk about smooth muscle cells contracting in reaction to HIGH BP...and so BP lowers BEYOND the constriction. But SYSTEMICALLY, when vasoconstriction happens, there is a net INCREASE in BP overall. If you had a garden hose and you squeezed the end of it to reduce water flow (vasoconstriction), then PAST the opening of the hose, the water will flow less (lower BP), but BEHIND the opening of the hose, there will be increased pressure. Does that help? As is often in physio...things aren't always black and white!
@@evasmits5189 No- "behind the hose" is the ENTIRE BODY. So systemic BP increases with vasoconstriction, but immediately LOCAL vasoconstriction causes decreased pressure. If the afferent arteriole vasoconsticts, BP past it decreases (because flow decreases). But if you think about systemic BP as a whole, vasoconstriction causes increased BP.
I absolutely adore the fact that you are so enthusiastic/animated when you instruct these topics. It rejuvenates my motivation to learn and to get excited about material. I think a lot of times students get bogged down in the dryness of material like this (I know I do) when we read it from bland textbooks that just spew out facts. Your enthusiasm when you teach makes me want to absorb the information and have it etched into my brain rather than just memorize it on a superficial level for a test I have in 2 days. Because of you, I see this information as a fascinating topic that I want to remember for years to come that maybe I could just spew out at a trivia game or use to my advantage if a family member is diagnosed with kidney disease. Regardless of my future uses for these facts, I really would like to thank you for putting in the time and effort to not only teach your viewers, but also to inspire us. If only there were more educators out in the world such as yourself. We appreciate you! Keep up the good work
Hi
I'm so glad I found your videos! I wasn't understanding how the myogenic mechanism worked and the way you explained it really helped.
So glad I found your videos!!! So simple and straight to the point. Thank you :)
Great video! I have one question though. In this video you're saying that the smooth muscle cells contract in reaction to a HIGH BP, thus lowering the amount of blood that enters the glomerulus. However in your next video about the juxtaglomerular apparatus, you tell us that as a reaction to LOW bloodpressure, the smooth muscle cells also CONTRACT, in order to increase the BP. How would you explain that these two mechanisms of contracting the smooth muscle cells have different reaction (decreasing or increasing BP)?
This is a super important question- thanks for asking. And the answer depends on is WHERE blood pressure changes in relation to the vasoconstriction. In this video, we talk about smooth muscle cells contracting in reaction to HIGH BP...and so BP lowers BEYOND the constriction. But SYSTEMICALLY, when vasoconstriction happens, there is a net INCREASE in BP overall. If you had a garden hose and you squeezed the end of it to reduce water flow (vasoconstriction), then PAST the opening of the hose, the water will flow less (lower BP), but BEHIND the opening of the hose, there will be increased pressure. Does that help? As is often in physio...things aren't always black and white!
@@wendy-riggs And the "behind the opening of the hose, there will be increased pressure" is in the nefron in the afferent arteriole?
@@evasmits5189 No- "behind the hose" is the ENTIRE BODY. So systemic BP increases with vasoconstriction, but immediately LOCAL vasoconstriction causes decreased pressure. If the afferent arteriole vasoconsticts, BP past it decreases (because flow decreases). But if you think about systemic BP as a whole, vasoconstriction causes increased BP.
@@wendy-riggs Thank you so much! That was really clear :)
@@evasmits5189 No problem! It is a common confusion-- and it is always fun to bounce things around with my UA-cam students!
Very 'simple' and easy to understand. Thank you for posting!
Love your video! You explained myogenic mechanism so easy!
You are the BEST at explaining this stuff!!! thank you sooooo much!!!!
Wendy, thank you
Any prostaglandins role?
Great video, thank you!!
better than the book!
You are amazing!
thankssss a lotttttt!!! you're amazingggg :D
We meet again