Understanding Predictive Markers of METABOLIC Dysfunction (Dr. Sara Gottfried & Dr. Casey Means)
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- Опубліковано 29 чер 2024
- Dr. Sara Gottfried - a pioneer in health, research, and education - has seen more than 25,000 patients over the past two decades. She's a physician scientist, who graduated from Harvard Medical School and MIT, and completed her Residency at the University of California, San Francisco.
Dr. Gottfried is the Director of Precision Medicine at The Marcus Institute of Integrative Health, Thomas Jefferson University, where she specializes in identifying the underlying causes of her patient's conditions to achieve lasting health transformation, not just symptom management.
Dr. Gottfried has published five books, including multiple New York Times bestsellers, such as The Hormone Cure, The Hormone Reset Diet, and Younger. Her latest book has just been published, Women Food and Hormones.
In this episode of A Whole New Level, Dr. Casey Means, Co-founder and Chief Medical Officer of Levels, covered a number of topics from Dr. Gottfried’s new book.
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00:00 - Intro
00:40 - The vital role of metabolism
04:42- Metabolic data should be democratized
07:58 - Women and the keto diet
09:37 - Women are considered "too complicated"
15:44 - Every person needs a unique diet
20:00 - Diet shouldn't be like politics
24:20 - The ideal fasting length
31:10 - The role of testosterone
37:58- Physicians should not be gatekeepers to health
01:01:37 - The relationship between genes and our environment
👋 WHO WE ARE:
Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.
🔗 LINKS:
Transcripts & Show notes: www.levelshealth.com/podcasts...
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#metabolicfitness #metabolism #metabolichealth #metabolic #continuousglucosemonitoring #glucosemonitoring #cgm #cgmlife #biowearables #biohacking - Наука та технологія
A wonderful discussion with two brilliant minds.🌟🌟 Thank you!😊
When Casey Means speaks, the world of unhealthy people should listen intently. Not just her Levels paradigm, but her advise on diet and exercise to control metabolic health are invaluable and I'm sure lead to improved health outcomes.
Thank you so much Dr. Means for all that you contribute; I have followed your advice for years now with positive and lasting results.
Amazing! Thanks for your early support of what we're building 😊
Yes, twin studies are so fascinating! Such opportunity for showing people differences between genetics, epigenetics, and personal choice critical thought about metabolic health.
I agree that personalizing is the way to go. In that sense, I don't like novel 'one size fits all' injections.
What a great interview! I am an identical twin, 52 years old, both in perimenopause and we both did The DNA Company test which I believe tested 67 genes and we were identical in all but 2! GSTT1 (my sister had 2 copies and I had 1) and APOE (my sister is 3/4 and I am 3/3). It was SO interesting to see how the genes are not "stand alone" and how they, combined with other gene types, can impact mood and behavior, diet and nutrition, how we absorb nutrients, exercise, sleep, cardiovascular health, etc. We were suboptimal in so many (including insulin resistance which was a wakeup call especially for my sister who did have 1 copy of the APOE4 gene) that it was a game changer for us. I spent over 20 hours putting a spreadsheet together comparing our outcomes and defining the changes we both had to make. Like stated, it is not a diagnosis or a death sentence but a FANTASTIC tool to help improve so many aspects of your life. My sister also got the LEVELS CGM and did many tests. It is so wonderful to see a shift in the world of health and wellness. We are no longer held captive by what our doctors say (not a slam against doctors! they have a job to do!) but we have knowledge at our fingertips so we can be the dictators of our own lifespan and healthspan. Thank you from the bottom of my heart for this critical information! p.s. Dr. Gottfried was so right about Keto...we needed a low carb diet but also one lower in saturated fat, so we have a revised keto diet and feeling great. Also, we IF and that has been a miracle. Thank you again! Kellie
are you more protein?
@@joanneclark8256most definitely! Especially at our age. And an increase in fiber intake as well.
Very encouraging that this system complexity is beginning to be looked at by you two, and becoming more empowering than within the medical paradigm standard viewpoints. I might suggest considering how another important factor should be paid attention to about this complexity. Reading research about the toxicology of the toxic metal lead, has made me aware that lead adversely affects metabolic pathways in many ways. How does blood lead (Pb) relate to the enzymatic pathways of uric acid and signaling for fat storage or burning glucose? I know that it has widespread disruptive effects on many physiologic pathways, is elevated in bone as a storage pool along with calcium (100 t0 1000 x's in modern bone compared to prehistoric bone), can substitute for Zn in protein production (making the folding faulty to the point of dysfunction or worse more toxic), have adverse neuropathology effects on intelligence, and mitochondrial energy production. It mobilizes out of bone when the body comes under stresses such as pregnancy, illness, old age, low D3, low Zn etc. and becomes toxic again in circulation at just the most vulnerable times physiologically. As such, it IS another co-morbidity, not commonly recognized as being additive (or synergistic) with other co-morbidities for worse ICU outcomes. Lead pollution has been improved a lot, but much of it still remains as current exposure, and as body burden in bone. Reading the literature, I very frequently see how metabolic health is adversely affected. IMHO
Pb can reduce glutathione, GABA, D3, cytochrome P450, and therefore mitochondrial function as a start on adverse effects when the body comes under stress and needs Ca from bones... Pb comes out too.
A wearable blood lead monitor would be such a good tool. I wonder how far away that might be? Seems possible with pointed engineering future.
Thank you, ladies.
I finally got a blood test and felt so empowered knowing what my levels are. I've been kind of afraid to find out.
Interesting video, al lot of information. But to me very confusing, still don’t know how to proceed
Getting into the guts of metabolism, yummi :) Thank you very much!
buying dr.sara book, going to follow her on Instagram too
1:03:00 Structure your day around the exercise, consistency
Have a Levels CGM. Now I’m going to get the book!
How much did it cost? I didn't c a price
24:39 oh no 14 hours is just too short for me, my body definitely don't like too much carbs tho I eat lots of fibres, nor do I like eating all the time... for me 18-20 hours fasting is the sweetest length, I feel good and lean, Is there signs to know if cortisol is high without testing it?
what about inositol ???
It isnt until 1.06 that u FINALLY get around to some useful information. Jeez!
1:02:00 for me although I liked the whole thing
is carnivore ok? some say going well
They are mostly interested in selling you guys $400 App, and stupid book ,that’s the bottom line.