TWiV 1130: Clinical update with Dr. Daniel Griffin
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- Опубліковано 7 сер 2024
- In his weekly clinical update, Dr. Griffin discusses H5N1 influenza in the bird and cow communities of Colorado and Michigan and dengue in New York and the US before reviewing the recent statistics on SARS-CoV-2 infection, the absence of association with proton pump inhibitors and COVID-19 severity in children, where to find PEMGARDA, the effectiveness of molnupiravir and dexamethasone, convalescent plasma, what to do when healthcare workers succumb to SARS-CoV-2 infection, a resource of long COVID answers, how the WHO and CDC define long COVID and how it compares to ME/CSF.
Show notes at www.microbe.tv/twiv/twiv-1130/
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_UA-cam timestamps by Les_
00:37 Bow Tie Fecal Pathogens
02:30 Quotation (E. Hemingway)
03:17 H5N1 influenza in the bird and cow communities of Colorado and Michigan
04:25 dengue in New York and the US
06:58 *CoViD*
05:52 Global warning helps disease vectors
reviewing the recent statistics on SARS-CoV-2 infection
08:53 the absence of association with proton pump inhibitors and COVID-19 severity in children
11:10 where to find PEMGARDA
11:21 Early Viral phase
the effectiveness of molnupiravir and dexamethasone
convalescent plasma
11:57 Early inflammatory phase
12:12 Long CoViD
what to do when healthcare workers succumb to SARS-CoV-2 infection
12:20 a resource of long COVID answers
18:00 Possible mechanisms driving long CoViD
how the WHO and CDC define long COVID and how it compares to ME/CSF.
30:38 How to donate
31:05 *Your Qs answered by Dr D*
see microbe.tv/twiv/twiv-1130-letters/
31:11 Leah
32:27 Julie
34:25 Ian
38:48 Anonymous
_Audio podcast timestamps by Jolene_
Other than the natural and rather slow change of the climate, which is cyclical, there is no climate change. If you pretend that there is, you are being led about by the nose.
Thanks for the timestamps.
I had no idea there was so much about long covid,great episode!
My long haul started Dec 2020 no gap between acute and long Covid. It just morphed. Horrible year 1, bad year 2, management since. Quit work for 2 years, managing now. Thanks for keeping the word going.
I also developed Long Covid early on, after contracting the wild strain of Covid -19 in February 2020. I felt lucky to survive the first year. My heathcare org. didn't recognize Long Covid until April 2020. They have a clinic that is useless, but other departments have been helpful. I've kept up following the science and been willing to try therapies that relate to my ongoing symptoms. I hope you are recovering. ❤
@@katiehettinger7857 Thanks Katie it’s been a rough ride. Keep up the good work. All the best.
Huge thank you.
Great to hear about that body promoting evidence based understanding of Long Covid.
And great to get a clear explanation of times of infectivity. I've copied the transcript for future reference.
great long covid info, thank you
Exactly right! I look forward to more but what a daunting task after looking at the lists presented by Daniel. Such a complex disease to start with with its phases and symptoms and then more of that complexity in long COVID mechanisms and treatments.
This is such exciting information on what is being done to address PASC. I am sharing this episode as much as possible!
Done worry if you repeat a quote- they deem repeating. What a creative and fun way to start a show that is so important to our well being!
Thank you.
Low serotonin in long covid: this again points to covid caused gastrointestinal damage preventing vitamin B12 absorption, since b12 is needed in synthesis of serotonin. Lack of b12 could also somewhat explain change in gut microbiome. Also anemia seems to be frequent in long covid.
8:23 is it possible that the Winter Peak and Summer Surge are driven by the increased amount of people indoors to escape extreme cold/heat? I know you mentioned that not nearly enough of the funds to improve HVAC filtration were used to purpose. 🤷♀️ if COVID isn’t seasonal -the way the flu is-then could peak/surge be caused by a ‘tipping point’ of % of time a higher % of bodies spend in enclosed spaces?
Are any respiratory viruses seasonal? I’ve had colds in spring and summer months long before Covid reared its ugly head. I blamed my kids at the time as being the lurg spreaders as their immune systems had not met any of usual suspect viruses until they started school. Stay safe😊
@HeatherOrdover-CraftLit I agree the key factor is the degree of close contact and that depends on people's behaviour. The US is a large country and has different climates, that tend to blur the picture. The UK is smaller and the pattern is much clearer. There are two peaks, one in late Summer/early Autumn and another early in January.
Yes, Yes. It's so good to see my own thoughts written by someone else. Summer increases could also be caused by the large number of people who travel in summer, similar to holiday surges after each family gathering, but less concentrated in time. One person arriving home from a vacation in Puerto Rico could spark an uptick in several communities (not just their own) if they are shedding virus while traveling.
I only meant to add another cause on top of the indoor transmission due to heat and AC, not to discount your thoughts. I agree with you as to the biggest cause of summer uptick. And that "tipping point" is crucial to understanding how surges work.
@@robinirons541 Both RSV and the Flu are seasonal.
At 11:10 in the “Link” where to get Pemgarda, the link merely takes you to an old link that is basically an old press release by the FDA. No actual contact information is provided! As this is the second time this has happened I thought I would let you folks know. Vincent and Daniel still love you guys though. ❤
Excellent program, thanks Vincent and Daniel
Great show! Thank you.
Great listen from the doctors.
Thank you very much
Thanks for the overview Of long Covid. Very helpful
Fantastic information. Thanks!
Would like to hear more on NAC
NAC is a sulfur- like supplement. I used it with bromelain, ( pineapple enzyme) it was supposed to break down the spike. A couple of weeks use did seem to help.
Theoretically,NAC decrease blood viscousity
long covid, did he mention 'grinding of the teeth'? bruxism?
What period in the history of the earth did the climate of earth not change? I'm not denying change is happening.. just acknowledging change has been and will continue to happen.
The climate has always changed and long before man started having a fire to keep warm.
True, but the rate of change is unprecedented. Look up all other periods of changes. Even those marked as fast are nothing compared to the rising temperatures we are facing today. Consider the fact in a short time, the plant will not support the present human population.
Extremely rapid anthropogenic global warming, overwhelming evidence, virulently denied by reactionary elements & fossil fuel interests -- now the argument is a rather lame, well, the climate always changes, still denial, still missing the point
I discussed Pemgarda with my oncologist yesterday. Our hospital is not yet set up for it. She said it is not yet known how long the immunity will last. We are thinking of getting in November to have the protection during the winter peak.
If you were to get it now, you would be eligible again in November (every 90 days). If you are at higher risk or immunocompromised, it certainly couldn't hurt as we are tending to see summer surges still!
First!
2nd !
Maybe it's the lighting, but Daniel looks aged. But then again this is the fifth year of the pandemic. Damn I look aged!
“Compare yourself to who you were yesterday, not to who someone else is today.
Jordan B. Peterson”
Wisdom-no matter who says it. (The above is Peterson’s rule #4 of 12, I think.)
One day these guys are gonna have one hell of a retraction to make tho i hazard a guess it will be of the form of "well we never said xxxxxx"
Sounds like you don't understand how science works
What part of this discussion of research do you disagree with and what are your credentials?
Don’t feed the Trolls (or their Bots) 😉
Rubbish