What do you think about the conclusion at the end of the video? 💊 MicroVitamin (multivitamin & mineral that I take): drstanfield.com/products/microvitamin 📜 Roadmap - how to look young & feel strong: drstanfield.com/pages/roadmap • Join Patreon For Early Video Access & Discord Chat: www.patreon.com/bradstanfieldmd
This supports my suspicion that the clinical data is far from robust, BUT: I'm still going to keep trying lion's mane and other mushrooms supplements for a while. Already shelled out for a two-month supply and it can't hurt, right?
@@ShiceSquad I got the same info out of it. You gotta think about what the medicines we take do and HOW they do it. For instance, Lions Mane is stimulating growth & that takes energy. Its a good thing - but you can't take it every day or that extra growth with drain your reserves. Like echinachia ... that is a great medicine but if you take it every day it will exhaust the metabolic source it uses to do its job. Just something to consider. anything can be "over-done"
@@DETHTWUKTAUR Goodie, I might as well try some echinacea too, thanks. Regarding the lack of data, it occurred to me that it costs so much money to run a clinical trial, nobody would ever do that if they can't patent the result, so there probably never will be any robust data on the efficacy of medicinal plants. Only testimonials from all the people who tried them. Anyway, thanks to this video, I cut my lion's mane intake down to once every four days.
@@ShiceSquad This has been a pleasant and productive internet time. Yeah if you are interested in this stuff check out the subject "PharmaCOGNACY (sp)". It is the bridge between organic chemistry/botany and pharmaCOLOGY. You can learn about the source of the "effects" we are both chasing. For instance, Basil has several varieties that grow chemicals found in OTHER species! like there is a cinnamon basil that produces a chemical in cinnamon tree bark that is really good for insulin/glucose regulation. its easy to just keep taking things & add to the list of "good effects" or "super foods" that hold vital nutrients, but the rabbit hole never ends.
@shicesquad Not quite true about the clinical trials, natural substances are being tried, but I don't know about the ratio of pharma to natural substance.
I had a stroke Sept. 28th 2020 (32yrs Old at the time) got out of the hospital a month later. My brother had done research on Lion's mane and I decided to try it in July 2021 (my recovery was already happening before trying the shroom powder). 3 days after taking "very potent" capsules my body got a very strong tingling in my right shoulder (affected side) that gradually moved in about 4 hours to the left side of my head leaving a tingle trail while it moved. Went to my doctor and he said everything I described of feeling stinging and tingles sounds like wallerian nerve regeneration. Fast forward to today and I am feeling almost everything tingling, last year I could barely walk and the right side of my body had no feeling, now I'm walking by myself, using my right hand to write this message. I still have a ways until I'm 100% again, but I think ever since I had that tingle episode, the mushroom powder boosted my cells to make a new connection in my brain and that started or accelerated all of the sensation all over my affected side and nerve regeneration. Since then these tingles haven't stopped and my body feels better everyday. Thank you for reading if you did, God bless 🙏✝️
You know what I love about this doctor? He is willing to admit knowledge gaps between clinical trials and personal beliefs of success. So long as a patient is not taking a toxic substance or protocol, I feel as though he would respect the possibility that we simply do not know the pharmacological effects of natural compounds. I love this guy. He has no ego and genuinely cares about his practice, patients and audience.
i felt lust like that for a while, but sometimes I think he actually goes too far in ruling things out as a waste of money, simply due to not enough data and often says things like fasting is no good because people on it do no better than Mediterranean diet. but when you look at what he is saying, he is saying the average person doesn't do better on it, but some do and some don't, so the key really is to not discount it but to see if you can become one of the people who do better on it. This is no doubt because his advise is for the average person, as he doesn't have time to get to know people well enough to know if they could be extraordinary. As in individual I have the opportunity to be better than average, just under half of people are ;)
Not useful (time filler?) to repeat and repeat that looking only at the Abstract and Conclusions only gives limited insight (potentially overly-positive or overly negative indications). This doc is refreshingly scientific altho it seems also possibly overly dismissive of the chances of the potential of lions mane. I’ll need to look further to see things like whether whole mushroom l.m. Works whereas extracts don’t. What varieties of LM to go for, safety, valuable effects etc. It may be wise but it is also frustrating as hell for everything to Always end in “further research is needed” unless…further research (right research uncontaminated by moneyed interests) IS needed.
I appreciate the unbiased look at the research. I have been taking a mushroom blend supplement for 60 days and my mind has improved tremendously. This definitely could be placebo effect. But my head is much clearer and I can focus longer. I have diagnosed adhd which I didn’t medicate for because of the side effects I have with amphetamines I self medicated with coffee my entire adult life drinking 8-12 cups a day to focus enough to life a productive life In 2 months I’m down to 2-4 cups a day and more productive then I have ever been in my life. I feel as though if I had it when I was younger I would have gone to and graduated college.
Wow 8-12 cups? I would never be able to sleep and trembling uncontrollably with that amount of caffeine. I usually have two green matcha tea's a day with 200mg L-theanine supplement with each and that keeps me going all day.
I've only taken lions mane for a week I keep thinking it might be just the placebo affect but I haven't been this sharp since I took the horrible drug amnatryptoline ten years ago for sleep. I'm able to concentrate deeply again and I haven't been completely out of it for days now so far it's been the best supplement I've ever taken by far.
recent studies show good benefits. this video is old and this guy is way to sceptical. he finds research that suits him. any study can be modelled to say whatever you want it to say. big pharma is an expert at making natural remedies seem like quackery.
I'm another person who benefits from using it. I'm 49 and I know for a fact that I'm mentally sharper than when I was in college. I also take a good quality iron/b12 supplement which gives me more energy. You have to address your greatest nutritional deficiency (or deficiencies) as well, if you have any. But if you do, you'll NOTICE that you're sharper and feel better
After getting on lithium and an antidepressant for my bipolar disorder, I felt duller than before. I try to watch Jeopardy every day and I found I was much better at the game once I was taking Lion's Mane. I also felt sharper, like I had been before the meds.
I have taken lions mane and reishi for the past 6 months and i must say i achieved so much more in this 6 months than in the past 5 years. Mental clarity, good sleep, good gut health. I took on a copywriting course in the past months and finally opened my own business. This is my experience with mushrooms so far. Could you possible talk about Shilajit Dr.Brad?
Isn't that also can be placebo? I mean human mind is crazy if u belived something then that thing can be true, I think our mind have a big effect on our body like when you get adrenaline or in dangerous situation like saving a child that stuck on car your mind literally will unlocked ur body limit to save that girl basically max power.
The frustrating thing of course is that there are no really long term studies. I would imagine that if Lions Mane or any other mushroom genuinely benefited brain function it would likely take years to have a really quantifiable impact. But I think that as a general rule, its a good idea to have a good range of fungi in your diet. Apart from anything else, they seem to have natural prebiotics so could help gut health.
I know many might suffer from less rigourous TCM methodology and be lost in translations but i wonder if perhaps there are some rigorous long-term mushroom studies done in a place like China or Russia by legit scientists?
@@DrBradStanfield I have low BH4 which is causing catastrophic issues with my Neurotransmitters impacting Dopamine Norepinephrine Nitric oxide Melatonin and serotonin. Would love for you to do some videos on NTs including gaba glutamate which I expect is an issue
First study says that uric acid levels were different between groups at week 16, which has had some hype recently for its role in cognitive impairment and vascular diseases. Wonder if the mushrooms' effect could be at least partially mediated by acting on these
@@mattkolb2649 How did you find out about BH4 issues, as that sounds pretty specific? I have unresolved issues with brain fog that comes with any stimulation, ranging from sugar to video games (but otherwise I'm fine). I also have developed insomnia, and it sounds like it could be a mild case of such a thing given the explanation.
@@DrBradStanfieldyes please cover more videos on supplements or vitamins reversing cognitive decline / vascular &/or other forms of dementia / Alzheimer’s?? Vascular dementia is a condition my grandmother currently suffers from & I’ve noticed significant memory changes in her recently. She supplemented 4 years ago on lions mane with mild/moderate improvement but at this point I’d say it’s worth trying again vs not at all to see if she’ll respond better now. Seems there is more data on it now too. This is definitely an area of research that fascinates me. Nootropics is also interesting topic for me as a guy who has add/adhd but doesn’t want to be on stimulants like aderall due to its adverse effects: nootropics can be a natural alternative. Would love a research summary in this too! 🙏🏼 thanks for considering…
At 94,my father had colon cancer and had to get a section of his colon taken out. The cancer was determined to be stage 5 and they said that in his condition, chemo and radiation would probably kill him, and that it had gone to far to try that, especially at his age. So we got on the internet and found some studies done by the Japanese in cahoots with Paul Stamets that had showed good results against cancer. So he started taking one tablespoon a day of Paul Stamets 7 mushroom blend that is made from 7 medicinal mushroom mycelium, and also Turkeytail mushroom that had the mycelium and the fruiting bodies of Turkeytail in it. In one Japanese Turkeytail study they said it cured certain cancers, so he decide take Turkeytail also. He took one heaping tablespoon of each( the 7 mushroom blend and the Turkeytail) in a half a glass of water per day. In 3 months he got tested for cancer and his blood was cancer free. He died 3 years later( wasn't supposed to live a few months) wat they thought was because of the damage the cancer had done to the rest of his body because he caught it so late. A couple of months before he died he was tested for cancer and he was declared cancer free. Was this just a powerful placebo effect? I think not. He was a scientists and I was the one who told him about those mushrooms and the studies done b the Japanese. He only tried it because there were real studies done, but he didn't really believe he could be cured of stage 5 cancer. I think it was mostly the mushrooms that cued him. He was at the end of his life anyway and why he died just could also have been from old age, but stage 5 colon cancer surely didn't help. But, he was declared cancer free.
I'd love to see you make a video on the research behind turkey tail, chaga, and reishi. From what I understand, these three have some of the best anti oxidants properties of medicinal mushrooms.
I've been taking Lion's Mane in my morning fiber mix for about a month. Not sure that I am any smarter, but I can find my way from one room to another in the dark.
👆👆hit him up, he sells shrooms, Dmt, LSD, bars, microdosing capsules, spores, mushrooms🍄 and all psychedelic products, his items comes dosage and guidance. He ships worldwide and swiftly..
My five senses seemed to have improved when I was on regular lion's mane. Almost like I was a super cognizant Spiderman. Some quite lucid dreams though.
Generally the abstract should fully represent the data. The report at 2:00 shows a significant increase in learning effect, and that dip is after they're off Lion's Mane (also significant). It doesn't matter if there is a learning effect, compare the rates of learning. The report at 4:40 was one with mycelia, most studies are done with the fruiting body. Should be mentioned. Also, From Wiki: "The most frequently noted disadvantage of the MMSE relates to its lack of sensitivity to mild cognitive impairment and its failure to adequately discriminate patients with mild Alzheimer's disease from normal patients". "The content of the MMSE is highly verbal, lacking sufficient items to adequately measure visuospatial and/or constructional praxis". I don't think the test is sophisticated enough, or has enough resolution to make and determinations here unless there was a massive jump in cognition in specific areas of the brain. Couldn't increases in some areas be relevant and be diluted on the overall score? Meaning the statement you highlighted on 5:09 of the video may not be counter-evidence to the abstract?
Matthew - very familiar with MMSE, I used to administer it. Here is one of the big problems in a study like this. You have patients with possible cognitive impairment, right? So HOW MUCH cognitive testing will they tolerate and sit through? The MMSE takes about 10 minutes to administer, and it covers a lot of domains - simple calculations, spatial reasoning, abstraction, etc. The patients DO have to use their brains. Impaired patients DO NOT like the tests and really struggle. If you get them to stay and work for a half hour, you are very lucky. So if you give the MMSE and 2 or 3 other measures, you have patients who are 'just about over it', you know? They are saying things like "That's enough doc!" Agree totally about the failure of cognitive SCREENING tests (quick looks at cognition to see if more indepth testing is required) to pick up subtle deficits. That is a HUGE problem in cognitive testing. And although some patients claim they feel a benefit, sometimes you can't actually see it on the test scores where usually improving by a point or two could just be due to other variables (the patient felt better on the second day, they drank coffee before the second testing session, they slept better before the second testing, etc, etc etc). Remember you only have 30 points. Example, it they score a 28 the first testing session and then a 29 the second time, was it Lions Mane or just a familiarity and comfort knowing what kind of questions are going to be asked during the second assessment (and the first time they didn't know what to expect, and they were nervous)? Very hard and not very useful to see ANY study that shows a 1-2 point improvement on a COGNITIVE SCREENER (I am NOT saying ALL TYPES of NEUROPSYCHOLOGICAL tests here, but specifically QUICK BRIEF COGNITIVE SCREENERS) and make some claim about that. Such a claim - in the case I'm describing - would not be very relevant.
Thanks for this. It's good to hear from someone with a deeper understanding of clinical studies than I possess. My family has a history of Alzheimers, so I'm always interested in new information on the subject. I am currently taking Lion's Mane, but don't really have any idea if it's doing any good. If it's not harmful I'll probably continue to take it for the time being.
The Alzheimer's studies are very promising. I would keep taking it if I were you. My family has the same. I can tell a difference but my Lion's Mane is combined with DMAE.
While anecdotal, there are quite a few reports of people posting online saying that taking lion's mane blunted their libido. Not sure if this was only with high doses and for chronic use, but I'd be interested to see long-term studies take a look at that more objectively
I have adhd and I stopped taking stimulant medication because I was getting to many side effects and couldn’t sleep, then I heard about lions mane in a support group and it’s absolutely amazing, it starts working straight away and within a week it feels like I have the same concentration and memory capability as I did when I was on the stimulant but with no side effects and no coming down from the medication and feeling worse than I did before taking it.
Lion's mane is just a really good mushroom in general. Even if it doesn't have clinical benefits beyond other mushrooms, it's still got a lot of things going for it. It's low-calorie, very high in nutrients per calorie, has no notable contraindications or side-effects beyond the possibility of allergies, and it has a very agreeable flavor and texture. So, why not?
No offense, but this is a redundant argument. There are plenty of food sources that offer these things that we know are perfectly safe. The question here is whether they are safe to take and whether they are safe to treat and/or to prevent certain things.
@@teddybearroosevelt1847 It's not redundant. When people advice you to take other things that are not perfectly safe, have 1001 side effects, all to fix one problem while causing possibly a dozen others, are not good for taste or pleasure either, it is a valid argument. I will take a agreeable tasting item with decent range of health boosts, even if it is lacking the full effect toward X or Y problem, over a synthetic pharmaceutical with all kinds of "unintended" consequences any day.
I swear by Lions Mane. I've been taking it for years, and it really improved my ailing memory. Numbers stick in my short-term memory longer and words I never would have remembered come back to me. I got my father on it too and he also believes it works. Don't let this video deter you from giving it a shot.
This is excellent clinical transparency and it's hard to find that these days. I used to know a senior medic who would encourage me to lie to my patients and a medical officer who would get mad if I let my patients read the clinical notes about them. It's nice to know professionalism is out there somewhere.
They say you cant really test for creativity and people argue that iq tests dont encapsulate human intelligence very well either. So who knows how lionsmane could affect different things outside of the tests in this study. By the way, I personally take lionsmane and I swear i can notice it's effects on things like curiosity, creativity, willingness to learn new things, noticing and remembering things in my environment better.
Lionsmane in the morning and Reishi in the evening. I have been doing this for around a year now and my cognitive ability and stress response and overall physical/mental/spiritual wellbeing have markedly improved.
Thx for the video. I've bought this dried in bags at Asian markets, it's called "monkey head" mushroom there. I've also grown it from a spore log. It looks like a white terry cloth towel.
Important note: Studies show that after stopping taking lion's mane, cognitive perfomance declined (back to baseline) so the important question is: does it provide permanent improvement in the long term? Otherwise what is the point of consuming it apart from as a nootropic during exam period?
I tried lions mane extract from different brands and was convinced this mushroom is exaggerated. Then I decided to try it fresh and purchased a kit online. I harvested 250 grams of lion's mane and consumed it raw. I believe I got a huge memory boost that day and was very surprised. Some of the effects wear off but some of them are still ongoing.
Awesome 😀 It scares me to use money on something that might be exaggerated for the purpose of sale. It is also expensive to buy fresh lion's mane, and it takes time to grow on tree logs. Thank you for sharing your experience. I might start with dried lion's mane and make it into a powder at home and drink it as tea. Less expensive. Hopefully it will give same benefit as fresh🧚♀ 😀
I was hit by a car 5 years ago and temporarily lost my memory. I still have problems with it but i started to learn another language, which has helped immensely but i started lions mane 9 months ago. I take a ten blend. Highly recommend it. I feel younger in my brain then i have in years and I'm 43.
I tried powdered lions mane for a year and did not notice a major difference, but I felt like there was a slight increase in focus and cognition (potentially placebo). I stopped taking it for a year. After a year off I began taking a tincture around 3 months ago. I noticed within 5 minutes of taking the tincture what I describe as a clearing of my mind and a calm energy and ability to focus. Over the winter holidays I was visiting my mother and brothers, and due to my curiosity I gave them both the recommended dosage of the tincture. Within 5-10 minutes they both reported the same experience I had. I am not sure it is helping me to regenerate neurons (obviously), but I feel like it is helping with my brain function. I can not explain nor guarantee this experience, but I have continued to take it, and my mother and two brothers take it now. It may just be a placebo, and we may just be a gullible family, but I enjoy the perceived effects I get from it. I hope to see more research on the effects. Thank Dr. Brad for your honesty and explanations on hard to comprehend studies and topics! Your work is greatly appreciated.
@@Vgallo Tincture is alcohol version of some herbs, fruits, shrooms etc. In this case you take shrooms and you pure alcohol to them. Vodka or spirit is best. Then you leave them for some time (like 2-4 weeks). Then you can drink it or use it or apply to skin etc. Some are using pure spirit (like 95%) or vodka. I am preparing a lot of tinctures myself. Herbal ones, shroom ones, propolis, fruit ones and others. One of my favourite is walnut tincture. For that best if you have young, not ripe walnuts, still in green shell/skin. After you cut them on half walnuts are still white and bitter in taste. I cover them with 50% alcohol and leave them in dark, cool space (in my case basement). Alcohol is very good solvent and extract all active substances.
I suffer from long Covid since November 2020, my main symptoms are brain fog, memory loss and ear sensitivity. Since there’s no help from the medical field into this condition I started doing research on ways to help me, which lead me to lion’s mane. I tried different brands, and did tons of research and at last I found the supposed highest quality brand that uses both water extraction and alcohol extraction methods. I was very hopeful that this would help me but it had a negative effect on me, I can’t prove it through testing or any other way but empirically everytime I tried it, it made my hearing worse and worse. It is a strange type of hearing loss where only the low frequencies seem to have been affected and it doesn’t show on audiograms, which I’ve had 2 of, but it’s very noticeable in daily life and when listening to music. I wanted this supplement to work which is why I gave it so many chances but sadly it had a negative impact on me. I’m assuming that it works as a sort of nerve stimulator which is probably counterproductive since it feels like my nerves and immune system are already working on overload from long Covid. Again, this is all empirical based on my intuition since there’s so little research and it’s not understood at all what’s happening to all of us suffering with this condition.
Hello, im seeing this a lot in people with long covid and vaccine injury with MCAS (Mast Cell Activation Syndrome), mast cells form part of your immune system.....covid and the MRNA vaccines can cause these mast cells to release a inappropriate amount chemicals in the body. Anything from chronic allergies, panic attacks, chronic fatigue and histamine toxicity. I had someone who never had panic attacks in her life, yet she was having severe panic attacks in bed. Because mast cells were dumping huge amounts of histamine and her diet was adding even more histamine.....it was way to much for her body to handle. Mast Cell Activation is a autoimmune problem that is not widely known by doctors.....especially GPs. Seek out a naturopath or functional medical practitioner that has experience in MCAS and see how you go...cheers Gary
Thanks for that robust analysis Brad. A couple of years ago I would watch one of your videos and dred another suppliment being added to my ever growing stack.
Did keto and relatively strong dose of lions mane for 3 months.. did eeg brain scan and no abnormalities found… stopped the keto and lions mane and symptoms of epilepsy returned.. back on lions mane and transitioning to keto.. already feeling better and will get another eeg to test in a couple months. If again no abnormalities I might make a documentary as I am a film maker.
I bought some growing kits, spore prints, spawns, liquid culture and psychedelic products from an online supplier and they are affordable and discreetly delivered
Just took 2Gs of Lion's Mane. It has a soothing calming effect. This could help with memory retention, as stress is a huge factor in learning disabilities.
I have started taking lion's mane recently (14 days now), and my headaches are gone. I'm also having dreams again. Also, I'm super focused, and I seem to have a sharper memory. It's been so good to me. PS* I didn't know what Lion's Mane was for when I bought it. It was just on sale on my favorite supplement online store, so I had a go. My experience is definitely not a placebo. I can certainly say it works, knowing what I know now.
I take lionsmane for neuropathy in my feet, have been for a few years. I had been taking three different drugs for neuropathy and restless leg syndrome and it still took an hour or two to get to sleep and I didn't sleep through the night. Two or three weeks into taking lionsmane I felt like the pain was less. Over time I started reducing the drugs (Neurontin was one of them), and in about a year I was off all three drugs. I still feel it in my feet some when I go to bed, but it isn't painful and doesn't disrupt my sleep.
@@Donnamg100 I took two 500mg capsules daily for a couple of years. the past few months I have been taking only one capsule daily, seems to still be working.
Nice examination of the studies. It's amazing that trial authors pump up the effects but when you look at the actual results shows no real result. It makes you wonder about their motivation.
Thank you for the valuable content Dr Stanfield. Could you please shed some light on the research of other mushroom supplement such as AHCC, reishi or cordycep ?
Thank you for your leadership. We are constantly bombarded by fake news. For that reason your hoghly objective analysis of the supporting data is very valuable. If I fing the mushroom at the korean market I will try it, but definitely I will not waste my money on a supplement.
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to get here
Psychedelics are the reason why i didn’t take my life when i was at my end. I was stripped of my ego and saw the beauty of life and interconnectivity and even though i still battle anxiety and depression, I’m doing better everyday and will never think in such a self destructive way again.
LSD and mushrooms completely changed my whole outlook on life. I became a better version of myself This experience gave me a lot of confidence about my self and my body. A bunch of bad thought / behavior patterns were broken. One of these was pretty bad OCD that made me wash my hands a lot. It gave me a lot of hope that things will be fine, this is the one thing that I heard throughout the trip: Everything is alright. The main reason for the trip was my severe depression and it definitely helped me (although it's not gone). Before all I could do was lay in bed. Now I am trying to rebuild my life one step at a time which wasn't possible before."
Thanks so much! A really fair view of this mushroom. I have used mushrooms for many year and will vouch for their energy. For the first time I am now growing Lionsmane in the living room! Great fun anyway!
Well if lion's mane is taken in heavy doses. It can raise HDL cholesterol by 30% can lower LDL cholesterol by 45%. It also lowers triglycerides. If you can get your HDL above 60 you really start to see some brain protecting benefits and hard protecting benefits.
👆👆hit him up, he sells shrooms, Dmt, LSD, bars, microdosing capsules, spores, mushrooms🍄 and all psychedelic products, his items comes dosage and guidance. He ships worldwide and swiftly..
Raising your HDL has no health benefits. It is not something you should target. Sure a higher HDL:LDL ratio is seen in healhy people but the high HDL is caused by the improved lipid health, not the other way around, it's just a marker. Plus if you get it too high, like 80+, you increase stroke risk.
Hi Brad, on nerve growth/repair there is something that does work. NervGen has NVG-291. It just passed human Phase 1(safety). In rats paralyzed by both spinal crush and induced MS the majority regained the ability to walk, none in placebo group regained walking ability. In a separate study last summer in strokes in mice after many weeks before treatment they did way better in maze tests than placebo. Are you aware of NVG-291? Think you will find of interest. Why the FDA did not allow the safety tests in people who could benefit is frustrating as it will slow down human proof by a year. The animal proof is there and under microscope human neurons do start regrowing. From Case/Western Med School. Phase 2 starts Q3. I was not aware of Lions Mane on this issue. Thanks.
A friend of mine who was having fiberalga attacks started adding linos mane to his coffee and 4 weeks after taking lions mane for three weeks most of the pain was gone and improvements continue
I've watched a few videos on lion's mane or mushroom research and the main consensus at the moment is that when it comes to human trials there are VERY few. This tells me that even IF the one or four studies out there were significant in findings it wouldn't be enough. I believe the placebo effect also lasts for around 3 months if I remember correctly. It's all interesting. I'm trying it for myself because it seems safe for me to give it a go, but I do have some skepticism still. I would love to see more studies done in the future. There are too few human studies to state its benefits or lack there of.
I believe mushrooms are high in purines, which adds to uric acid. Low uric acid diets warn you away from mushrooms. And apparently controlling uric acid is as important as controlling glucose. There have been several podcasts with Purlmutter who’s pushing his new book, Drop Acid. It sure scared me into buying a uric acid tester and in fact I found elevated levels. Now looking into low uric acid diets and life style. All that said, thank you for your diligence in teasing out what matters.
There's a lot of chat at the moment about uric acid. In short, there's no evidence of health benefits if you lower uric acid (aside if it's extremely high and if a patient is suffering from gout attacks)
The placebo effect is an interesting topic all on its own, and the total role it plays in human clinical trials shouldn’t be understated. but I believe this is part of the human factor that we have to deal with in any clinical studies. Human error is something we try to minimize as much as possible since it skews the data. Whenever you give something to a patient In a clinical study, you not only have that potential from the clinicians side, but also on the patient end as well. This is partly why we hold clinical studies with animals, since humans and animals have very similar neurochemical structures. That way any potential for human error is cut in half. For example, we found that antidepressants even work on Lobsters 😂 so they have some studies that have been done with mice... Paul Stamets discussed this on Joe Rogan a while back. And I’m not an expert by any means so forgive me if I get something wrong. Anyways, there are neurotoxins in the brain that hinders brain functions. These increase as we get older, adding to the overall cognitive decline with age. This is true for humans just as much as it is for other animals. They tested the effects of lions mane on mice and found that it reverses the effect these neurotoxins have. In general, they helped promote nerve growth and protect the brain from damage caused by these neurotoxins. Although the research is still in its infancy, animal studies typically translate over for humans. The research is far from done although, from what we know so far, taking lions mane is relatively safe and beneficial for cognitive development. It might be worth a try if you suffer from severe brain fog and depression like symptoms… but always consult with your physician before starting anything new since you never know whether there is a potential for medications to have negative interactions or something 🤷🏼♂️
The first two to three weeks I didn’t notice much until I started my new job which is in an office with computers doing tech support. The last similar job I lost it due to my ADD. Regardless of my medications, I still encountered the usual symptoms of confusion and disorientation. I’ve been taking two medications, the second one I had just started (after job loss ) and maybe a week later is when I started taking the lions mane. When I started the new job I was just more than halfway finished with the capsules so let’s analyze this: Previous job- Because of my symptoms I had a hard time learning the new program. Despite reading the procedures every day that I was there, I felt lost often as well as drowsy. Current job- This one also has the same system as the previous one so I dreaded and feared having to go through the same thing again. But something weird happened. While I started training I recognized almost everything that I had seen from the previous job, including the program, what each process does and other aspects. I’ve NEVER experienced anything like this in my life . The first two weeks in the new job I felt very competent, something I rarely feel. I kept thinking that it was just the two meds kicking in but unfortunately, as I was ending my second week I ran out of the Lion’s Mane. I proceeded with my life towards the third week and the end of the third week which is when I’m writing this. Gradually through the week, my mind started to feel foggy again to which today I made a small blunder to a customer’s account. I’m still training so I let my senior coworker know so he could revise what I did thus correcting it in the end. After I noticed this I almost allowed myself to fall in despair because I don’t want to go through this like last time again. Conclusively I came back to the seller to order it, but I see that the shipping speed is too slow and I won’t get the product until May. I canceled the order and went with another seller with the same type of product which will hopefully arrive today. I can’t risk waiting for this seller to finally send it over a week later. In a nutshell it’s a pity that the benefits of Lion’s Mane are only present with continuing doses. According to scientists, Lion’s Mane has been observed to aid in growing new neurons. But once you stop taking it, does it mean that those neurons it helped grow die off???
It was recommended to me to help with nerve regeneration as I have MS I bought some in a pipette bottle from Fat Fox n the UK Two days in and my energy level is ↗️⬆️⬆️⬆️⬆️! I'm buzzing and I'm motivated. I feel really positive! PS I'm also taking Turkey Tail from the same place
Here's another anecdote. I like looking into different kind of supplements for different reasons. Been taking Lion's Mane for a month now and haven't felt anything at all, not even the slightest placebo effect whatsoever. Gonna stop once the pills are finished.
Hello, I would like to ask if there is any interesting data for white jelly mushroom extracts (Tremella Fuciformis) improving cognitive function. Thanks for your videos, it's always interesting to have your insights!
Thank for the analysis of the studies. We eat mushrooms we forage for, twice a day. The positive data presented in studies for mushrooms is not as strong as we would like to see. People i know who forage for mushrooms are in good health and have a very healthy life style.
I ordered a pound of organic micronized lion's mane powder and it was a bit expensive, but it's nice to know that at least I'm getting something organic and nutritious that equates to more like ten pounds of fresh lion's mane mushroom. Mushrooms are about nine or ten times more concentrated when dried
Great video! Really appreciate all the time and work you put into actually reading the papers and explaining things to us in easy to understand terms. There's so much hype about everything it's hard to discern the wheat from the chaff.
Your high quality investigative reporting just caused me to lose a wager I made last week with a big shot John Hopkins MD girlfriend regarding BDNF and mushroom derived neurogenesis. She claimed I snuck by my whole career only reading abstracts and now you have proven her allegation. If I confess with self-effacement, I could keep my relationship.
Which mushrooms specifically? There are thousands of varieties. You’re being very vague when you say eating mushrooms didn’t show significant improvement for heart disease. On the Macrobiotic Diet it is the Shiitake Mushrooms that are recommended for those with cancer. Maitake Mushrooms also are sometimes recommended. The Chinese are very fond of the Reishi Mushrooms. Even white button mushrooms you can buy in any supermarket contain betaglucans which can be beneficial but the medicinal mushrooms are preferable.
I DO take lions mane every AM & definitely feel a cognitive benefit… my mom has dementia so I’m taking any & all I supp’s & lifestyle to stave off this possibility… thanks Brad 👍
The point of having a placebo group is to isolate the effect from factors like getting better at a particular test. That's why they used a placebo group, so we can compare vs. placebo. I don't even care, how exactly lion's mane caused the improvement vs. placebo in the test - 16% improvement is VERY impressing. Also another study ou didn't mention found an improvement in sleep, anxiety and depression scores of depressed people by 30-40%, which were maintained after wash-out, which is also very impressive. Overall the evidence and the degree of positive impact on brain health appears to be much greater and broader than, say for creatine.
I take a six mushroom complex and it certainly clears any morning fog. No stimulation as such, but I guess I can describe it as "removing irrelevancies and improving focus". I use some cordyceps powder when I go to the gym, and it's not unlike creatine - in that it shortens recovery time and improves performance and motivation. To me, it's no placebo.
So I've conducted research studies previously. It is good that is working for you, no argument there. Here is the 'rub' so to speak in doing studies. If you are going to avoid ethical violations, you have to report the data that you get from the participants. It is the AVERAGE result that you report, not the outstanding benefit that a few might REALLY receive. For example, It could be that 3 or 4 patients get absolutely outstanding results, but the other 30 don't improve. So what happens when you average that together? You see NO REAL difference between the group who got the intervention and the group that got a placebo type intervention. And you have to report that. REMEMBER you are trying to report 'what will do the most good for the most people' right? So you have to say that there really wasn't a significant effect. If those 30 non responders bought Lions Mane, they wouldn't and didn't improve. You could however say in your comment sections, that there were a few 'outliers' who showed marked improvement, , but you better have subject data and be able to back it up. Other researchers CAN and sometimes DO ask to see your data, and they will re-run the statistical analysis. They BETTER get the same findings, which suggest you DID NOT cheat or falsify data. If you did and you are in an academic or healthcare setting, your career is probably OVER. Many of those in the anti science movement don't understand the limits of science and the many checks and balances in place to try to prevent mis representations of data.
Thank you! I'm constantly looking for ideas to aid my 90-year-old father in staying highly functional (which he is now thanks to dedicated exercise and good diet.) I'm gonna pass on this one.
@@hoangthai3974 Small meals, small protein servings with beans, leafy greens, nuts, and tomatoes. 2 eggs every morning with oatmeal for breakfast. 30 minutes fast walking every day (used to do wind sprints but has recently given that up..) Pushups and Sit-ups. Supplements: Broccomax, CurcuBrain, TruNiagen, Daily multivitamin, plus an Rx statin for blood pressure. A couple glasses of wine or beer a few times a week - never smoked. Stays very active, visits friends several times a week.
@@KenOtwell Thank you for your response! I will look into these supplements that he is taking. I want a supplement for brain health and prevention of Alzheimer’s disease. Is he on any supplement for prevention of Alzheimer’s disease. Thank you!
That sounds brilliant asleep and dreaming is my favourite point in the day. I've just started lions main and has been good and remember some of my dreams. What's the most captuals youv taken at a time. I've took 3 . Going to try 4 then 5 .
This is exactly what happened to me and my wife after taking it. We got very vivid wild dreams the both of us. I actually didn't like it so i started taking it in the mornings instead of before bed and the dreams stopped same for my wife. I wonder what it's doing to give such vivid dreams.
I appreciate looking final state of the math. It's a real problem in science that we have catchy and inspiring titles and sound bites for studies that have uninspiring mathematical results.
Some general ideas I wanna shoot out. If it encourages nerve regrowth, shouldn't you eat things to help build those nerves? Also nerve regrowth doesn't mean you will instantly be good at things, so the longer trials should be more commonplace for something like this.
Testament to the placebo effect. On occasion, I take a mixed mushroom supplement in AM on empty stomach. Doubt it's much more than placebo effect, but feels good.
My dog (14+ years) showed signs of doggy dementia. He did sundowning and left us both without much sleep every night because of it. I started giving him Lion's Mane and after just a short time on it, he slept through the nights again and during the day he is his normal self again, even playful with toys. It was quite a transformation. I will give this Lion's mane powder until the day he'll die and I'm thinking of starting to us it for myself. This was NOT a waste of money. If I had listened to our Vet and used all the meds he wanted to give him, my dog would be dead by now.
👆👆hit him up, he sells shrooms, Dmt, LSD, bars, microdosing capsules, spores, mushrooms🍄 and all psychedelic products, his items comes dosage and guidance. He ships worldwide and swiftly..
The problem with scientific studies is that its like comparing car performance on a closed track. The only way to know HOW a car performs is on a highway or in a city among the other variables. Scientific method is a GREAT tool...and provides a necessary dimension of sight. However, I believe that the laboratory of life, while not controlled obviously, yields MORE than "the sum of the parts" and shows possibilities that the lab doesn't allow. With this said I've personally SEEN Lion's Mane make a huge difference on someone who had cognitive decline due to a stroke. It was almost miraculous. " There are more things in heaven and earth, Horatio, than are dreamt of in (our) philosophy." (Billy Shakespeare, lol) BTW: Love the channel...love the content. I love to use your channel for the important scientific perspective. My comment here is not at all disrespect...simply an alternative (and unscientific, subjective) view. Keep on rocking Dr. Brad! 🙂
Well the data lines of the placebo groups vs the ones taking it are not as high. Also regarding people who say it works brings up a question. How long and consistent is the placebo effect anyway?
I started taking a couple of weeks ago. I have a severe case of ADD, but I'm giving it a chance since I haven't finished the capsules yet and currently there has been no improvement.
Brain health is indeed a very important part of healthy aging. How is the clinical data for actively training your brain at old age? Does e.g learning a new language or a musical instrument just make you better at one skill, or does it transfer to other areas and general improve mental health, lower the the risk of dementia etc?
👆👆hit him up, he sells shrooms, Dmt, LSD, bars, microdosing capsules, spores, mushrooms🍄 and all psychedelic products, his items comes dosage and guidance. He ships worldwide and swiftly..
What do you think about the conclusion at the end of the video?
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This supports my suspicion that the clinical data is far from robust, BUT: I'm still going to keep trying lion's mane and other mushrooms supplements for a while. Already shelled out for a two-month supply and it can't hurt, right?
@@ShiceSquad I got the same info out of it. You gotta think about what the medicines we take do and HOW they do it. For instance, Lions Mane is stimulating growth & that takes energy. Its a good thing - but you can't take it every day or that extra growth with drain your reserves. Like echinachia ... that is a great medicine but if you take it every day it will exhaust the metabolic source it uses to do its job.
Just something to consider.
anything can be "over-done"
@@DETHTWUKTAUR Goodie, I might as well try some echinacea too, thanks. Regarding the lack of data, it occurred to me that it costs so much money to run a clinical trial, nobody would ever do that if they can't patent the result, so there probably never will be any robust data on the efficacy of medicinal plants. Only testimonials from all the people who tried them. Anyway, thanks to this video, I cut my lion's mane intake down to once every four days.
@@ShiceSquad This has been a pleasant and productive internet time. Yeah if you are interested in this stuff check out the subject "PharmaCOGNACY (sp)". It is the bridge between organic chemistry/botany and pharmaCOLOGY. You can learn about the source of the "effects" we are both chasing. For instance, Basil has several varieties that grow chemicals found in OTHER species! like there is a cinnamon basil that produces a chemical in cinnamon tree bark that is really good for insulin/glucose regulation.
its easy to just keep taking things & add to the list of "good effects" or "super foods" that hold vital nutrients, but the rabbit hole never ends.
@shicesquad Not quite true about the clinical trials, natural substances are being tried, but I don't know about the ratio of pharma to natural substance.
I’ve been addicted to heroin for 11 years, but after trying out psilocybin treatment I will be 2 years clean.
I would love to try shrooms, does anyone know where I can source them?
@@loganturner9175 Yes, cole.shroomm!*
The trips I’ve been having have really helped me a lot.
@@Alex_146 is he on insta?
Of course, cole.shroomm!*
I had a stroke Sept. 28th 2020 (32yrs Old at the time) got out of the hospital a month later. My brother had done research on Lion's mane and I decided to try it in July 2021 (my recovery was already happening before trying the shroom powder). 3 days after taking "very potent" capsules my body got a very strong tingling in my right shoulder (affected side) that gradually moved in about 4 hours to the left side of my head leaving a tingle trail while it moved. Went to my doctor and he said everything I described of feeling stinging and tingles sounds like wallerian nerve regeneration. Fast forward to today and I am feeling almost everything tingling, last year I could barely walk and the right side of my body had no feeling, now I'm walking by myself, using my right hand to write this message. I still have a ways until I'm 100% again, but I think ever since I had that tingle episode, the mushroom powder boosted my cells to make a new connection in my brain and that started or accelerated all of the sensation all over my affected side and nerve regeneration. Since then these tingles haven't stopped and my body feels better everyday. Thank you for reading if you did, God bless 🙏✝️
thats awesome man Con Fn grats on that!!! lol :p
Love it when a plan comes together.............
Br thank you for sharing your story
Love this.
So great!!! Would you share which supplement you did take? Name and Dosis?
You know what I love about this doctor? He is willing to admit knowledge gaps between clinical trials and personal beliefs of success. So long as a patient is not taking a toxic substance or protocol, I feel as though he would respect the possibility that we simply do not know the pharmacological effects of natural compounds. I love this guy. He has no ego and genuinely cares about his practice, patients and audience.
i felt lust like that for a while, but sometimes I think he actually goes too far in ruling things out as a waste of money, simply due to not enough data and often says things like fasting is no good because people on it do no better than Mediterranean diet. but when you look at what he is saying, he is saying the average person doesn't do better on it, but some do and some don't, so the key really is to not discount it but to see if you can become one of the people who do better on it. This is no doubt because his advise is for the average person, as he doesn't have time to get to know people well enough to know if they could be extraordinary. As in individual I have the opportunity to be better than average, just under half of people are ;)
How do you know he has no ego?
Not useful (time filler?) to repeat and repeat that looking only at the Abstract and Conclusions only gives limited insight (potentially overly-positive or overly negative indications). This doc is refreshingly scientific altho it seems also possibly overly dismissive of the chances of the potential of lions mane. I’ll need to look further to see things like whether whole mushroom l.m. Works whereas extracts don’t. What varieties of LM to go for, safety, valuable effects etc. It may be wise but it is also frustrating as hell for everything to Always end in “further research is needed” unless…further research (right research uncontaminated by moneyed interests) IS needed.
@@teddybearroosevelt1847 Isn't it obvious? He's a humble man.
I agree with you, but I'd def change the title of the video tho.. it is misleading
I appreciate the unbiased look at the research. I have been taking a mushroom blend supplement for 60 days and my mind has improved tremendously. This definitely could be placebo effect. But my head is much clearer and I can focus longer.
I have diagnosed adhd which I didn’t medicate for because of the side effects I have with amphetamines
I self medicated with coffee my entire adult life drinking 8-12 cups a day to focus enough to life a productive life
In 2 months I’m down to 2-4 cups a day and more productive then I have ever been in my life. I feel as though if I had it when I was younger I would have gone to and graduated college.
Do you take anything else with your coffee? What do you do that you're productive on?
Wow 8-12 cups? I would never be able to sleep and trembling uncontrollably with that amount of caffeine. I usually have two green matcha tea's a day with 200mg L-theanine supplement with each and that keeps me going all day.
which mushroom blend are you taking?
I agree.
I've only taken lions mane for a week I keep thinking it might be just the placebo affect but I haven't been this sharp since I took the horrible drug amnatryptoline ten years ago for sleep. I'm able to concentrate deeply again and I haven't been completely out of it for days now so far it's been the best supplement I've ever taken by far.
How are you now?
He’s dead
recent studies show good benefits. this video is old and this guy is way to sceptical. he finds research that suits him. any study can be modelled to say whatever you want it to say. big pharma is an expert at making natural remedies seem like quackery.
I'm another person who benefits from using it. I'm 49 and I know for a fact that I'm mentally sharper than when I was in college. I also take a good quality iron/b12 supplement which gives me more energy. You have to address your greatest nutritional deficiency (or deficiencies) as well, if you have any. But if you do, you'll NOTICE that you're sharper and feel better
After getting on lithium and an antidepressant for my bipolar disorder, I felt duller than before.
I try to watch Jeopardy every day and I found I was much better at the game once I was taking Lion's Mane. I also felt sharper, like I had been before the meds.
I have taken lions mane and reishi for the past 6 months and i must say i achieved so much more in this 6 months than in the past 5 years. Mental clarity, good sleep, good gut health. I took on a copywriting course in the past months and finally opened my own business. This is my experience with mushrooms so far. Could you possible talk about Shilajit Dr.Brad?
@Elina Roberts please do so. I will appreciate that:)
@Elina Roberts Nothing is coming up:(
@@dariorito2369 "Elina Roberts" is a spam / scam.
I'm happy for you that things are going well, by the way.
Isn't that also can be placebo? I mean human mind is crazy if u belived something then that thing can be true, I think our mind have a big effect on our body like when you get adrenaline or in dangerous situation like saving a child that stuck on car your mind literally will unlocked ur body limit to save that girl basically max power.
The frustrating thing of course is that there are no really long term studies. I would imagine that if Lions Mane or any other mushroom genuinely benefited brain function it would likely take years to have a really quantifiable impact. But I think that as a general rule, its a good idea to have a good range of fungi in your diet. Apart from anything else, they seem to have natural prebiotics so could help gut health.
Based on cost benefit....
Agreed about the long term, adequately powered trials. And that a diet and varied diet is key
I know many might suffer from less rigourous TCM methodology and be lost in translations but i wonder if perhaps there are some rigorous long-term mushroom studies done in a place like China or Russia by legit scientists?
So you're saying we would benefit from some fungus among us?
@@imightbebiased9311 There is always room for a shroom in the room.
Great video,. I’d love to see more on brain health and neurotropics.
Thanks for watching, and for the suggestion
@@DrBradStanfield I have low BH4 which is causing catastrophic issues with my Neurotransmitters impacting Dopamine Norepinephrine Nitric oxide Melatonin and serotonin. Would love for you to do some videos on NTs including gaba glutamate which I expect is an issue
First study says that uric acid levels were different between groups at week 16, which has had some hype recently for its role in cognitive impairment and vascular diseases. Wonder if the mushrooms' effect could be at least partially mediated by acting on these
@@mattkolb2649 How did you find out about BH4 issues, as that sounds pretty specific? I have unresolved issues with brain fog that comes with any stimulation, ranging from sugar to video games (but otherwise I'm fine). I also have developed insomnia, and it sounds like it could be a mild case of such a thing given the explanation.
@@DrBradStanfieldyes please cover more videos on supplements or vitamins reversing cognitive decline / vascular &/or other forms of dementia / Alzheimer’s?? Vascular dementia is a condition my grandmother currently suffers from & I’ve noticed significant memory changes in her recently. She supplemented 4 years ago on lions mane with mild/moderate improvement but at this point I’d say it’s worth trying again vs not at all to see if she’ll respond better now. Seems there is more data on it now too. This is definitely an area of research that fascinates me. Nootropics is also interesting topic for me as a guy who has add/adhd but doesn’t want to be on stimulants like aderall due to its adverse effects: nootropics can be a natural alternative. Would love a research summary in this too! 🙏🏼 thanks for considering…
At 94,my father had colon cancer and had to get a section of his colon taken out. The cancer was determined to be stage 5 and they said that in his condition, chemo and radiation would probably kill him, and that it had gone to far to try that, especially at his age. So we got on the internet and found some studies done by the Japanese in cahoots with Paul Stamets that had showed good results against cancer. So he started taking one tablespoon a day of Paul Stamets 7 mushroom blend that is made from 7 medicinal mushroom mycelium, and also Turkeytail mushroom that had the mycelium and the fruiting bodies of Turkeytail in it. In one Japanese Turkeytail study they said it cured certain cancers, so he decide take Turkeytail also. He took one heaping tablespoon of each( the 7 mushroom blend and the Turkeytail) in a half a glass of water per day. In 3 months he got tested for cancer and his blood was cancer free. He died 3 years later( wasn't supposed to live a few months) wat they thought was because of the damage the cancer had done to the rest of his body because he caught it so late. A couple of months before he died he was tested for cancer and he was declared cancer free. Was this just a powerful placebo effect? I think not. He was a scientists and I was the one who told him about those mushrooms and the studies done b the Japanese. He only tried it because there were real studies done, but he didn't really believe he could be cured of stage 5 cancer. I think it was mostly the mushrooms that cued him. He was at the end of his life anyway and why he died just could also have been from old age, but stage 5 colon cancer surely didn't help. But, he was declared cancer free.
I'd love to see you make a video on the research behind turkey tail, chaga, and reishi. From what I understand, these three have some of the best anti oxidants properties of medicinal mushrooms.
Maitake as well
You should check out Tero Isokauppila’s book, he mentions those mushrooms and provides stories about people that have used them.
He also believes the body needs to have a BALANCE of oxidants and anti-oxidants
@Got NMN? He literally has videos giving advice on supplements worth taking, so obviously you didn't watch the rest of his shit.
@@haveagoodday9446 what bentley said, but also i dont believe op was talking about supplements rather the actual food
I've been taking Lion's Mane in my morning fiber mix for about a month.
Not sure that I am any smarter, but I can find my way from one room to another in the dark.
👆👆hit him up, he sells shrooms, Dmt, LSD, bars, microdosing capsules, spores, mushrooms🍄 and all psychedelic products, his items comes dosage and guidance. He ships worldwide and swiftly..
My five senses seemed to have improved when I was on regular lion's mane. Almost like I was a super cognizant Spiderman. Some quite lucid dreams though.
@@Iron-Bridge Good point about the dreaming; I have been experiencing that as well. I suspect it is a good sign.
😂😂
Fiber is bad for you.
Fantastic research. I always like the way you present evidence and conclusion. No bias. 👏👏👏
Generally the abstract should fully represent the data.
The report at 2:00 shows a significant increase in learning effect, and that dip is after they're off Lion's Mane (also significant). It doesn't matter if there is a learning effect, compare the rates of learning.
The report at 4:40 was one with mycelia, most studies are done with the fruiting body. Should be mentioned.
Also, From Wiki: "The most frequently noted disadvantage of the MMSE relates to its lack of sensitivity to mild cognitive impairment and its failure to adequately discriminate patients with mild Alzheimer's disease from normal patients". "The content of the MMSE is highly verbal, lacking sufficient items to adequately measure visuospatial and/or constructional praxis".
I don't think the test is sophisticated enough, or has enough resolution to make and determinations here unless there was a massive jump in cognition in specific areas of the brain. Couldn't increases in some areas be relevant and be diluted on the overall score? Meaning the statement you highlighted on 5:09 of the video may not be counter-evidence to the abstract?
Thank you for this information friend 🙏 😊
Matthew - very familiar with MMSE, I used to administer it. Here is one of the big problems in a study like this. You have patients with possible cognitive impairment, right? So HOW MUCH cognitive testing will they tolerate and sit through? The MMSE takes about 10 minutes to administer, and it covers a lot of domains - simple calculations, spatial reasoning, abstraction, etc. The patients DO have to use their brains. Impaired patients DO NOT like the tests and really struggle. If you get them to stay and work for a half hour, you are very lucky. So if you give the MMSE and 2 or 3 other measures, you have patients who are 'just about over it', you know? They are saying things like "That's enough doc!" Agree totally about the failure of cognitive SCREENING tests (quick looks at cognition to see if more indepth testing is required) to pick up subtle deficits. That is a HUGE problem in cognitive testing. And although some patients claim they feel a benefit, sometimes you can't actually see it on the test scores where usually improving by a point or two could just be due to other variables (the patient felt better on the second day, they drank coffee before the second testing session, they slept better before the second testing, etc, etc etc). Remember you only have 30 points. Example, it they score a 28 the first testing session and then a 29 the second time, was it Lions Mane or just a familiarity and comfort knowing what kind of questions are going to be asked during the second assessment (and the first time they didn't know what to expect, and they were nervous)? Very hard and not very useful to see ANY study that shows a 1-2 point improvement on a COGNITIVE SCREENER (I am NOT saying ALL TYPES of NEUROPSYCHOLOGICAL tests here, but specifically QUICK BRIEF COGNITIVE SCREENERS) and make some claim about that. Such a claim - in the case I'm describing - would not be very relevant.
Thanks for this. It's good to hear from someone with a deeper understanding of clinical studies than I possess. My family has a history of Alzheimers, so I'm always interested in new information on the subject. I am currently taking Lion's Mane, but don't really have any idea if it's doing any good. If it's not harmful I'll probably continue to take it for the time being.
The Alzheimer's studies are very promising. I would keep taking it if I were you. My family has the same. I can tell a difference but my Lion's Mane is combined with DMAE.
While anecdotal, there are quite a few reports of people posting online saying that taking lion's mane blunted their libido. Not sure if this was only with high doses and for chronic use, but I'd be interested to see long-term studies take a look at that more objectively
👆👆 he's got shrooms, LSD, bars, he's got a lot of good trippy stuffs, you can order from him 🍄 💊🍄🍫💯🔌
Maybe the increase in brain functions makes them unconsciously not want to reproduce anymore.
That's not necessarily a bad thing
@@omniXenderman Yes it is.
@@SeminarioMAE Not if you're single and trying to avoid the lusts of the flesh whilst waiting for your one and only.
I have adhd and I stopped taking stimulant medication because I was getting to many side effects and couldn’t sleep, then I heard about lions mane in a support group and it’s absolutely amazing, it starts working straight away and within a week it feels like I have the same concentration and memory capability as I did when I was on the stimulant but with no side effects and no coming down from the medication and feeling worse than I did before taking it.
Lion's mane is just a really good mushroom in general. Even if it doesn't have clinical benefits beyond other mushrooms, it's still got a lot of things going for it. It's low-calorie, very high in nutrients per calorie, has no notable contraindications or side-effects beyond the possibility of allergies, and it has a very agreeable flavor and texture. So, why not?
No offense, but this is a redundant argument. There are plenty of food sources that offer these things that we know are perfectly safe. The question here is whether they are safe to take and whether they are safe to treat and/or to prevent certain things.
@@teddybearroosevelt1847 It's not redundant. When people advice you to take other things that are not perfectly safe, have 1001 side effects, all to fix one problem while causing possibly a dozen others, are not good for taste or pleasure either, it is a valid argument. I will take a agreeable tasting item with decent range of health boosts, even if it is lacking the full effect toward X or Y problem, over a synthetic pharmaceutical with all kinds of "unintended" consequences any day.
@@teddybearroosevelt1847 It's food.
I swear by Lions Mane. I've been taking it for years, and it really improved my ailing memory. Numbers stick in my short-term memory longer and words I never would have remembered come back to me. I got my father on it too and he also believes it works. Don't let this video deter you from giving it a shot.
This is excellent clinical transparency and it's hard to find that these days. I used to know a senior medic who would encourage me to lie to my patients and a medical officer who would get mad if I let my patients read the clinical notes about them. It's nice to know professionalism is out there somewhere.
I bet they got promotions over covid
They say you cant really test for creativity and people argue that iq tests dont encapsulate human intelligence very well either. So who knows how lionsmane could affect different things outside of the tests in this study.
By the way, I personally take lionsmane and I swear i can notice it's effects on things like curiosity, creativity, willingness to learn new things, noticing and remembering things in my environment better.
I've heard so many wonderful things about magic mushrooms but I can't easily get some, Is there any realiable source I can purchase from??
I'm so interested in the experience but am terrified of having a bad trip
I did two grams last time, it was a thrilling experience and I enjoyed it
Mushrooms aren't like acid. You don't hallucinate, you just see some colors, and things move. I've never heard of anyone having a bad trip on shrooms.
( doctor_spores). jason
Got psych's*
This whole thing is pretty new to me, can I try 3grams?
Lionsmane in the morning and Reishi in the evening. I have been doing this for around a year now and my cognitive ability and stress response and overall physical/mental/spiritual wellbeing have markedly improved.
Thx for the video. I've bought this dried in bags at Asian markets, it's called "monkey head" mushroom there. I've also grown it from a spore log. It looks like a white terry cloth towel.
This are all old studies, this shows how much catching Dr Stanfield needs to do. I was using this over a decade now
Important note: Studies show that after stopping taking lion's mane, cognitive perfomance declined (back to baseline) so the important question is: does it provide permanent improvement in the long term? Otherwise what is the point of consuming it apart from as a nootropic during exam period?
I tried lions mane extract from different brands and was convinced this mushroom is exaggerated. Then I decided to try it fresh and purchased a kit online. I harvested 250 grams of lion's mane and consumed it raw. I believe I got a huge memory boost that day and was very surprised. Some of the effects wear off but some of them are still ongoing.
troll
@@deeznuts3472troll deeznuts... 🤣 i must be dyslexic because thats what i saw lol
@@NotJam3s gatee
@@deeznuts3472 i dont know what that means
Awesome 😀 It scares me to use money on something that might be exaggerated for the purpose of sale. It is also expensive to buy fresh lion's mane, and it takes time to grow on tree logs. Thank you for sharing your experience. I might start with dried lion's mane and make it into a powder at home and drink it as tea. Less expensive. Hopefully it will give same benefit as fresh🧚♀ 😀
I was hit by a car 5 years ago and temporarily lost my memory. I still have problems with it but i started to learn another language, which has helped immensely but i started lions mane 9 months ago. I take a ten blend. Highly recommend it. I feel younger in my brain then i have in years and I'm 43.
I tried powdered lions mane for a year and did not notice a major difference, but I felt like there was a slight increase in focus and cognition (potentially placebo). I stopped taking it for a year. After a year off I began taking a tincture around 3 months ago. I noticed within 5 minutes of taking the tincture what I describe as a clearing of my mind and a calm energy and ability to focus. Over the winter holidays I was visiting my mother and brothers, and due to my curiosity I gave them both the recommended dosage of the tincture. Within 5-10 minutes they both reported the same experience I had. I am not sure it is helping me to regenerate neurons (obviously), but I feel like it is helping with my brain function. I can not explain nor guarantee this experience, but I have continued to take it, and my mother and two brothers take it now. It may just be a placebo, and we may just be a gullible family, but I enjoy the perceived effects I get from it. I hope to see more research on the effects.
Thank Dr. Brad for your honesty and explanations on hard to comprehend studies and topics! Your work is greatly appreciated.
Powder stuff you got is probably some shite sold as shroom.
What is the tincture?
@@Vgallo Tincture is alcohol version of some herbs, fruits, shrooms etc.
In this case you take shrooms and you pure alcohol to them. Vodka or spirit is best.
Then you leave them for some time (like 2-4 weeks). Then you can drink it or use it or apply to skin etc.
Some are using pure spirit (like 95%) or vodka.
I am preparing a lot of tinctures myself. Herbal ones, shroom ones, propolis, fruit ones and others. One of my favourite is walnut tincture. For that best if you have young, not ripe walnuts, still in green shell/skin. After you cut them on half walnuts are still white and bitter in taste. I cover them with 50% alcohol and leave them in dark, cool space (in my case basement). Alcohol is very good solvent and extract all active substances.
Thank You for your clear comment
Where did you get this tinture
It is very effective for me. I often feel positive and negative… placebo effects. In regards to the lions mane the effects are beyond doubt for me.
I suffer from long Covid since November 2020, my main symptoms are brain fog, memory loss and ear sensitivity. Since there’s no help from the medical field into this condition I started doing research on ways to help me, which lead me to lion’s mane. I tried different brands, and did tons of research and at last I found the supposed highest quality brand that uses both water extraction and alcohol extraction methods. I was very hopeful that this would help me but it had a negative effect on me, I can’t prove it through testing or any other way but empirically everytime I tried it, it made my hearing worse and worse. It is a strange type of hearing loss where only the low frequencies seem to have been affected and it doesn’t show on audiograms, which I’ve had 2 of, but it’s very noticeable in daily life and when listening to music. I wanted this supplement to work which is why I gave it so many chances but sadly it had a negative impact on me. I’m assuming that it works as a sort of nerve stimulator which is probably counterproductive since it feels like my nerves and immune system are already working on overload from long Covid. Again, this is all empirical based on my intuition since there’s so little research and it’s not understood at all what’s happening to all of us suffering with this condition.
Look into brain inflammation or neuro inflammation. Krill oil and vitamin d and may be even a keto diet could be beneficial
Thanks for sharing, hopefully you are improving
Radiation poisoning, not Covid
Hello, im seeing this a lot in people with long covid and vaccine injury with MCAS (Mast Cell Activation Syndrome), mast cells form part of your immune system.....covid and the MRNA vaccines can cause these mast cells to release a inappropriate amount chemicals in the body. Anything from chronic allergies, panic attacks, chronic fatigue and histamine toxicity. I had someone who never had panic attacks in her life, yet she was having severe panic attacks in bed. Because mast cells were dumping huge amounts of histamine and her diet was adding even more histamine.....it was way to much for her body to handle. Mast Cell Activation is a autoimmune problem that is not widely known by doctors.....especially GPs. Seek out a naturopath or functional medical practitioner that has experience in MCAS and see how you go...cheers Gary
Long Covid is basically a vaccine injury freaking criminals allowed to get away with this!
Loved this video. Science is HARD! Normal people including journalists only read the abstracts. Thanks for providing critical peer review.
Thanks for that robust analysis Brad. A couple of years ago I would watch one of your videos and dred another suppliment being added to my ever growing stack.
Did keto and relatively strong dose of lions mane for 3 months.. did eeg brain scan and no abnormalities found… stopped the keto and lions mane and symptoms of epilepsy returned.. back on lions mane and transitioning to keto.. already feeling better and will get another eeg to test in a couple months. If again no abnormalities I might make a documentary as I am a film maker.
I bought some growing kits, spore prints, spawns, liquid culture and psychedelic products from an online supplier and they are affordable and discreetly delivered
FROM
CRUISE_MYCOLOGIST
in
instagram
Any updates on this?
Just took 2Gs of Lion's Mane. It has a soothing calming effect. This could help with memory retention, as stress is a huge factor in learning disabilities.
Or you're experiencing placebo
I have started taking lion's mane recently (14 days now), and my headaches are gone. I'm also having dreams again. Also, I'm super focused, and I seem to have a sharper memory. It's been so good to me.
PS*
I didn't know what Lion's Mane was for when I bought it. It was just on sale on my favorite supplement online store, so I had a go. My experience is definitely not a placebo. I can certainly say it works, knowing what I know now.
Out of interest which supplement did you take?
@@Detechno77 CGN.
@@kahnjugaming Thanks
@@kahnjugaming Is that California Gold Nutrition?
sorry somewhat ignorant about diff brands
I take lionsmane for neuropathy in my feet, have been for a few years. I had been taking three different drugs for neuropathy and restless leg syndrome and it still took an hour or two to get to sleep and I didn't sleep through the night. Two or three weeks into taking lionsmane I felt like the pain was less. Over time I started reducing the drugs (Neurontin was one of them), and in about a year I was off all three drugs. I still feel it in my feet some when I go to bed, but it isn't painful and doesn't disrupt my sleep.
make sure you have plenty of vit b 12 as well
I have the beginnings of peripheral neuropathy. How much lion's mane did you take per day?
@@Donnamg100 I took two 500mg capsules daily for a couple of years. the past few months I have been taking only one capsule daily, seems to still be working.
Which brand do you take? Thanks
IT'S VERY GOOD. HAVE YOU TRIED THE GANODERMA MUSHROOM AND NONI JUICE?
Nice examination of the studies. It's amazing that trial authors pump up the effects but when you look at the actual results shows no real result. It makes you wonder about their motivation.
Thank you for the valuable content Dr Stanfield. Could you please shed some light on the research of other mushroom supplement such as AHCC, reishi or cordycep ?
Thank you for your leadership. We are constantly bombarded by fake news. For that reason your hoghly objective analysis of the supporting data is very valuable. If I fing the mushroom at the korean market I will try it, but definitely I will not waste my money on a supplement.
More on optimising cognition/brain function acutely and preserving it chronically would be great thanks!
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to get here
Psychedelics are the reason why i didn’t take my life when i was at my end. I was stripped of my ego and saw the beauty of life and interconnectivity and even though i still battle anxiety and depression, I’m doing better everyday and will never think in such a self destructive way again.
LSD and mushrooms completely changed my whole outlook on life. I became a better version of myself
This experience gave me a lot of confidence about my self and my body. A bunch of bad thought / behavior patterns were broken. One of these was pretty bad OCD that made me wash my hands a lot. It gave me a lot of hope that things will be fine, this is the one thing that I heard throughout the trip: Everything is alright. The main reason for the trip was my severe depression and it definitely helped me (although it's not gone). Before all I could do was lay in bed. Now I am trying to rebuild my life one step at a time which wasn't possible before."
[_James_tray]
Got psychs
@@sarahh321 Where to search?? Is it IG?
@@Jerryberger9235 Yes
Thanks so much! A really fair view of this mushroom. I have used mushrooms for many year and will vouch for their energy. For the first time I am now growing Lionsmane in the living room! Great fun anyway!
Well if lion's mane is taken in heavy doses. It can raise HDL cholesterol by 30% can lower LDL cholesterol by 45%. It also lowers triglycerides. If you can get your HDL above 60 you really start to see some brain protecting benefits and hard protecting benefits.
Link to any studies on this?
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Raising your HDL has no health benefits. It is not something you should target. Sure a higher HDL:LDL ratio is seen in healhy people but the high HDL is caused by the improved lipid health, not the other way around, it's just a marker. Plus if you get it too high, like 80+, you increase stroke risk.
I like scrutiny. Too many pharm trials are deemed positive towards getting approval for the product. How do I know? I am a human and know their greed.
Hi Brad, on nerve growth/repair there is something that does work. NervGen has NVG-291. It just passed human Phase 1(safety). In rats paralyzed by both spinal crush and induced MS the majority regained the ability to walk, none in placebo group regained walking ability. In a separate study last summer in strokes in mice after many weeks before treatment they did way better in maze tests than placebo. Are you aware of NVG-291? Think you will find of interest. Why the FDA did not allow the safety tests in people who could benefit is frustrating as it will slow down human proof by a year. The animal proof is there and under microscope human neurons do start regrowing. From Case/Western Med School. Phase 2 starts Q3.
I was not aware of Lions Mane on this issue. Thanks.
A friend of mine who was having fiberalga attacks started adding linos mane to his coffee and 4 weeks after taking lions mane for three weeks most of the pain was gone and improvements continue
Do you happen to know the dosage he is doing per day ?
I've watched a few videos on lion's mane or mushroom research and the main consensus at the moment is that when it comes to human trials there are VERY few. This tells me that even IF the one or four studies out there were significant in findings it wouldn't be enough. I believe the placebo effect also lasts for around 3 months if I remember correctly. It's all interesting. I'm trying it for myself because it seems safe for me to give it a go, but I do have some skepticism still. I would love to see more studies done in the future. There are too few human studies to state its benefits or lack there of.
I believe mushrooms are high in purines, which adds to uric acid. Low uric acid diets warn you away from mushrooms. And apparently controlling uric acid is as important as controlling glucose. There have been several podcasts with Purlmutter who’s pushing his new book, Drop Acid. It sure scared me into buying a uric acid tester and in fact I found elevated levels. Now looking into low uric acid diets and life style. All that said, thank you for your diligence in teasing out what matters.
There's a lot of chat at the moment about uric acid. In short, there's no evidence of health benefits if you lower uric acid (aside if it's extremely high and if a patient is suffering from gout attacks)
if this thing improved by a number of points on cognitive abilities tests in a few weeks, it would be like the best medicine ever found.
The placebo effect is an interesting topic all on its own, and the total role it plays in human clinical trials shouldn’t be understated. but I believe this is part of the human factor that we have to deal with in any clinical studies. Human error is something we try to minimize as much as possible since it skews the data. Whenever you give something to a patient In a clinical study, you not only have that potential from the clinicians side, but also on the patient end as well. This is partly why we hold clinical studies with animals, since humans and animals have very similar neurochemical structures. That way any potential for human error is cut in half. For example, we found that antidepressants even work on Lobsters 😂 so they have some studies that have been done with mice... Paul Stamets discussed this on Joe Rogan a while back. And I’m not an expert by any means so forgive me if I get something wrong. Anyways, there are neurotoxins in the brain that hinders brain functions. These increase as we get older, adding to the overall cognitive decline with age. This is true for humans just as much as it is for other animals. They tested the effects of lions mane on mice and found that it reverses the effect these neurotoxins have. In general, they helped promote nerve growth and protect the brain from damage caused by these neurotoxins. Although the research is still in its infancy, animal studies typically translate over for humans. The research is far from done although, from what we know so far, taking lions mane is relatively safe and beneficial for cognitive development. It might be worth a try if you suffer from severe brain fog and depression like symptoms… but always consult with your physician before starting anything new since you never know whether there is a potential for medications to have negative interactions or something 🤷🏼♂️
Placebo Effect is amazing… 🙌🏼 Dr Joe Dispenza’s work “You are the Placebo” is based. 🤯👍🏼
That's why we have randomised controlled trials.
The first two to three weeks I didn’t notice much until I started my new job which is in an office with computers doing tech support. The last similar job I lost it due to my ADD. Regardless of my medications, I still encountered the usual symptoms of confusion and disorientation. I’ve been taking two medications, the second one I had just started (after job loss ) and maybe a week later is when I started taking the lions mane. When I started the new job I was just more than halfway finished with the capsules so let’s analyze this:
Previous job- Because of my symptoms I had a hard time learning the new program. Despite reading the procedures every day that I was there, I felt lost often as well as drowsy. Current job- This one also has the same system as the previous one so I dreaded and feared having to go through the same thing again. But something weird happened. While I started training I recognized almost everything that I had seen from the previous job, including the program, what each process does and other aspects. I’ve NEVER experienced anything like this in my life . The first two weeks in the new job I felt very competent, something I rarely feel. I kept thinking that it was just the two meds kicking in but unfortunately, as I was ending my second week I ran out of the Lion’s Mane. I proceeded with my life towards the third week and the end of the third week which is when I’m writing this. Gradually through the week, my mind started to feel foggy again to which today I made a small blunder to a customer’s account. I’m still training so I let my senior coworker know so he could revise what I did thus correcting it in the end. After I noticed this I almost allowed myself to fall in despair because I don’t want to go through this like last time again.
Conclusively I came back to the seller to order it, but I see that the shipping speed is too slow and I won’t get the product until May. I canceled the order and went with another seller with the same type of product which will hopefully arrive today. I can’t risk waiting for this seller to finally send it over a week later.
In a nutshell it’s a pity that the benefits of Lion’s Mane are only present with continuing doses. According to scientists, Lion’s Mane has been observed to aid in growing new neurons. But once you stop taking it, does it mean that those neurons it helped grow die off???
What dosage were you taking?
It was recommended to me to help with nerve regeneration as I have MS
I bought some in a pipette bottle from Fat Fox n the UK
Two days in and my energy level is ↗️⬆️⬆️⬆️⬆️!
I'm buzzing and I'm motivated.
I feel really positive!
PS I'm also taking Turkey Tail from the same place
Here's another anecdote. I like looking into different kind of supplements for different reasons. Been taking Lion's Mane for a month now and haven't felt anything at all, not even the slightest placebo effect whatsoever. Gonna stop once the pills are finished.
Hello, I would like to ask if there is any interesting data for white jelly mushroom extracts (Tremella Fuciformis) improving cognitive function. Thanks for your videos, it's always interesting to have your insights!
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Thank for the analysis of the studies. We eat mushrooms we forage for, twice a day. The positive data presented in studies for mushrooms is not as strong as we would like to see. People i know who forage for mushrooms are in good health and have a very healthy life style.
As a doctor, do you care if a patient improves through placebo, or actual medicinal value? As long as they get better does the process really matter?
I ordered a pound of organic micronized lion's mane powder and it was a bit expensive, but it's nice to know that at least I'm getting something organic and nutritious that equates to more like ten pounds of fresh lion's mane mushroom. Mushrooms are about nine or ten times more concentrated when dried
Can you do video on the peptide BPC-157 please?
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I follow Dr John Campbell ,hes where i first heard about lions mane ,apparently it was a huge help to his brothers ,neurological issues.
You have quickly become my all-time favorite health resource. Thank you.
Great video! Really appreciate all the time and work you put into actually reading the papers and explaining things to us in easy to understand terms. There's so much hype about everything it's hard to discern the wheat from the chaff.
Your high quality investigative reporting just caused me to lose a wager I made last week with a big shot John Hopkins MD girlfriend regarding BDNF and mushroom derived neurogenesis. She claimed I snuck by my whole career only reading abstracts and now you have proven her allegation. If I confess with self-effacement, I could keep my relationship.
Humble brag.
diving deeper into the papers is crucial
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Which mushrooms specifically? There are thousands of varieties. You’re being very vague when you say eating mushrooms didn’t show significant improvement for heart disease. On the Macrobiotic Diet it is the Shiitake Mushrooms that are recommended for those with cancer. Maitake Mushrooms also are sometimes recommended. The Chinese are very fond of the Reishi Mushrooms. Even white button mushrooms you can buy in any supermarket contain betaglucans which can be beneficial but the medicinal mushrooms are preferable.
I DO take lions mane every AM & definitely feel a cognitive benefit… my mom has dementia so I’m taking any & all I supp’s & lifestyle to stave off this possibility… thanks Brad 👍
It would be helpful if you indicated what age group you are...
The point of having a placebo group is to isolate the effect from factors like getting better at a particular test.
That's why they used a placebo group, so we can compare vs. placebo. I don't even care, how exactly lion's mane caused the improvement vs. placebo in the test - 16% improvement is VERY impressing. Also another study ou didn't mention found an improvement in sleep, anxiety and depression scores of depressed people by 30-40%, which were maintained after wash-out, which is also very impressive. Overall the evidence and the degree of positive impact on brain health appears to be much greater and broader than, say for creatine.
im so excited..my lions main is arriving today....ill be adding it to my morning coffee :-) thats awesome about how the mice reacted...
Look at the focus in his eyes. This dude definitely taking the lion's mane
Pharmaceutical companies don't like medicinal mushrooms that work.
I take a six mushroom complex and it certainly clears any morning fog. No stimulation as such, but I guess I can describe it as "removing irrelevancies and improving focus".
I use some cordyceps powder when I go to the gym, and it's not unlike creatine - in that it shortens recovery time and improves performance and motivation. To me, it's no placebo.
So I've conducted research studies previously. It is good that is working for you, no argument there. Here is the 'rub' so to speak in doing studies. If you are going to avoid ethical violations, you have to report the data that you get from the participants. It is the AVERAGE result that you report, not the outstanding benefit that a few might REALLY receive. For example, It could be that 3 or 4 patients get absolutely outstanding results, but the other 30 don't improve. So what happens when you average that together? You see NO REAL difference between the group who got the intervention and the group that got a placebo type intervention. And you have to report that. REMEMBER you are trying to report 'what will do the most good for the most people' right? So you have to say that there really wasn't a significant effect. If those 30 non responders bought Lions Mane, they wouldn't and didn't improve. You could however say in your comment sections, that there were a few 'outliers' who showed marked improvement, , but you better have subject data and be able to back it up. Other researchers CAN and sometimes DO ask to see your data, and they will re-run the statistical analysis. They BETTER get the same findings, which suggest you DID NOT cheat or falsify data. If you did and you are in an academic or healthcare setting, your career is probably OVER. Many of those in the anti science movement don't understand the limits of science and the many checks and balances in place to try to prevent mis representations of data.
This is a good video to show how studies & papers are written to show what they want to
On days i take lions main with cordyceps i feel the difference in general mental ability and energy.
Thank you! I'm constantly looking for ideas to aid my 90-year-old father in staying highly functional (which he is now thanks to dedicated exercise and good diet.) I'm gonna pass on this one.
Siga dra Yanet Ramirez y Luis Antonio Melon Gomez ahi llegaran a 150 años saludables
Thanks for sharing Ken
Can you tell me what he is eating daily that attribute to him staying highly functional? Thank you
@@hoangthai3974 Small meals, small protein servings with beans, leafy greens, nuts, and tomatoes. 2 eggs every morning with oatmeal for breakfast. 30 minutes fast walking every day (used to do wind sprints but has recently given that up..) Pushups and Sit-ups. Supplements: Broccomax, CurcuBrain, TruNiagen, Daily multivitamin, plus an Rx statin for blood pressure. A couple glasses of wine or beer a few times a week - never smoked. Stays very active, visits friends several times a week.
@@KenOtwell Thank you for your response! I will look into these supplements that he is taking. I want a supplement for brain health and prevention of Alzheimer’s disease. Is he on any supplement for prevention of Alzheimer’s disease. Thank you!
TY Brad. This was a really interesting vid. Love the look.
It gave me extremely vivid dreams that I could completely recall.
That sounds brilliant asleep and dreaming is my favourite point in the day. I've just started lions main and has been good and remember some of my dreams. What's the most captuals youv taken at a time. I've took 3 . Going to try 4 then 5 .
This is exactly what happened to me and my wife after taking it. We got very vivid wild dreams the both of us. I actually didn't like it so i started taking it in the mornings instead of before bed and the dreams stopped same for my wife. I wonder what it's doing to give such vivid dreams.
@@suley951 personally I'd love that . Dreaming is my favourite part of living. No. Limitations no groundhog day. I can be some place else.
I appreciate looking final state of the math. It's a real problem in science that we have catchy and inspiring titles and sound bites for studies that have uninspiring mathematical results.
Great and simple information!
I took it for 2 days and had some extremely vivid and detailed dreams...
This Dr is always against anything natural!
Probably also ignores big pharma side affects on medicine he does promote!
anything fake*
very helpful with interpreting complicated looking studies
Some general ideas I wanna shoot out. If it encourages nerve regrowth, shouldn't you eat things to help build those nerves? Also nerve regrowth doesn't mean you will instantly be good at things, so the longer trials should be more commonplace for something like this.
Testament to the placebo effect. On occasion, I take a mixed mushroom supplement in AM on empty stomach. Doubt it's much more than placebo effect, but feels good.
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Its always a scam when its not a Chemical drug from a pharma company
My dog (14+ years) showed signs of doggy dementia. He did sundowning and left us both without much sleep every night because of it. I started giving him Lion's Mane and after just a short time on it, he slept through the nights again and during the day he is his normal self again, even playful with toys. It was quite a transformation. I will give this Lion's mane powder until the day he'll die and I'm thinking of starting to us it for myself. This was NOT a waste of money. If I had listened to our Vet and used all the meds he wanted to give him, my dog would be dead by now.
In the 2009 study ; If it was only the learning effect why would the scores drop off immediately after the supplement was discontinued at week 16 ?
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Appreciate your work a lot! Thanks!
Again, nailed it ! Bravo
Your new camera is great, nice image quality ;D
Lion's Mane subtly impacts my mood. I feel as though it contributes to muted emotional response, which allows me to make more logical decisions.
It’s a common side effect actually
Magnesium does that for me.
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Helped my ulnar nerve.
I love Lion's Maine. Been taking it for years.
The problem with scientific studies is that its like comparing car performance on a closed track. The only way to know HOW a car performs is on a highway or in a city among the other variables. Scientific method is a GREAT tool...and provides a necessary dimension of sight. However, I believe that the laboratory of life, while not controlled obviously, yields MORE than "the sum of the parts" and shows possibilities that the lab doesn't allow. With this said I've personally SEEN Lion's Mane make a huge difference on someone who had cognitive decline due to a stroke. It was almost miraculous. " There are more things in heaven and earth, Horatio, than are dreamt of in (our) philosophy." (Billy Shakespeare, lol) BTW: Love the channel...love the content. I love to use your channel for the important scientific perspective. My comment here is not at all disrespect...simply an alternative (and unscientific, subjective) view. Keep on rocking Dr. Brad! 🙂
Well the data lines of the placebo groups vs the ones taking it are not as high. Also regarding people who say it works brings up a question. How long and consistent is the placebo effect anyway?
I started taking a couple of weeks ago. I have a severe case of ADD, but I'm giving it a chance since I haven't finished the capsules yet and currently there has been no improvement.
Great analysis!!! Thanks Dr.!
Brain health is indeed a very important part of healthy aging. How is the clinical data for actively training your brain at old age? Does e.g learning a new language or a musical instrument just make you better at one skill, or does it transfer to other areas and general improve mental health, lower the the risk of dementia etc?
There are indeed studies that knowing more than one language is protective vs dementia. Your brain's pretty plastic.
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New camera appears to be more precise at picking up subtle differences in lighting.
It looks good, but I liked the old camera as well.
Thanks Brad. Fantastic as always!
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Lions mane mushrooms , is one of THE most exquisite taste I have ever eaten. 😍😍.
Like to hear your thoughts on rhodiola rosea supplement. Thank you for all your excellent work and insights.
Wonderful! Very instructive.
Well done!