BLOOD COAGULATION TESTS EXPLAINED. The mechanism of PT PTT BLEEDING TIME INR

[@MercyMburuNyakio]

I am an MBBS student from Kenya and oh my dear goodness, you have no idea how this simple thing has plagued me for yearssssss. Your explanation of INR IS SECOND TO NONE. THEY NEED THIS IN ALL INTRODUCTIONS OF THIS TOPIC WORLDWIDE!

[@Foxterrier]

Thank you very much. I am really happy to see that you find my video interesting. Hope you are doing well as mbbs student )

[@Bprimemod]

I have 2 hours left before my exam and I have never undertood this topic THIS clearly, thank you a lot!! 😄💜

[@Foxterrier]

Thank you very much )))

[@MercyMburuNyakio]

Your comment literally mad eme watch this video and now my butt is saved too!

[@Bprimemod]

@@MercyMburuNyakio HAHAAHSHHSHDH I'm so glad to hear that 😂🥳

[@lannang1070]

never understood this until now thanks

[@Foxterrier]

Thanks, appreciate it )))

[@jeffersonawah5929]

Thank you Sir. Great video

[@Foxterrier]

Thanks 😉

[@hectic_het]

Why some drugs require coagulation profile monitoring and some not? Which ? And Why?

[@Foxterrier]

Drugs like DOACs (Dabigatran, Rivaroxaban, Apixaban) and LMWH (Enoxaparin) have predictable absorption, distribution, metabolism, and excretion profiles, leading to stable anticoagulant effects at fixed doses.
In contrast to this drugs like warfarin / heparin have a very narrow therapeutic index, meaning that small changes in dose or drug levels can result in under-anticoagulation (leading to clotting) or over-anticoagulation (leading to bleeding) + some drugs have significant variability between patients due to genetic factors (e.g., warfarin metabolism varies due to CYP2C9 and VKORC1 genotypes).

[@hectic_het]

@@Foxterrier Thank you for the answer, you're lectures are short simple and very useful. Keep doing the good work 👍

[@Foxterrier]

@@hectic_het Thanks for watching )

[@maphekomoloto2961]

THANK YOU very much, you are a good teacher, you got a sub from me.

[@Foxterrier]

Thank you, appreciate it very much )

[@THEHOUSEOFBARKINGLAUGHTER]

THANK YOU SO MUCH

[@Foxterrier]

You are welcome )))