Coagulation Tests - PT, aPTT, TT, Fibrinogen, Mixing Studies
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- Опубліковано 12 січ 2025
- Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc)
Prothrombin Time (PT/INT),Activated Partial Thromboplastin Time (aPTT),Thrombin Time (TT),diluted Russell Viper Venom Test (dRVVT).
The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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This is good knowledge however the presenter is tooo fast, he is actually rushing through the staff. Please reduce the speed
Hey man loved your video, just another way I remember aPTT and PT is that you Play Table Tennis inside (intrinsic) and you Play Tennis outside (external).
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AT 13:20, Warfarin will not increase thrombin time since it works by inhibiting the synthesis of vitamin K that will affect the synthesis of prothrombin, however in TT test, thrombin is directly added to the plasma
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Dear M.P. it was awesome, like always. I had one last thought at the end: "Rolls-Royce?... it might feel like that from behind the wheel (for you) but surely it feels a Lambo Diablo from the passenger's seat." 😊 Special thanks for the warfarin info - on the platelets.
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13:16
I don't think so
Warfin affect 2 7 9 &10
So factor II (prothrombin) decreases
But in thrombin time you actually are testing fibrinogen
Fibrinogen production actually may increase from liver
So Thrombin Time isn't prolonged it's shorter
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Great video! Just a note, the Pro time usually is not prolonged with therapeutic levels of heparin because the reagent contains a heparin neutralizing agent.
Another side note is when you were describing drvvt testing, you mentioned patient's serum, but we still use plasma! (The blue top)
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Deficiency of Vit K why not affect prolong pTT as it share in synthesis of coagultion factor in intrinsic pathway?
hey medicos, I really appreciate your videos very great work and I totally watch them helped me a lot thanks for that but I have once concern
during 12:15 warfarin should prolong PT and heparin should prolong PTT unlike what you wrote, this information is from Amboss if am wrong please correct me
thank you and AMAZING VIDEOS KEEP IT UP
Heparin prolongs both PT and PTT.
Warfarin prolongs both PT and PTT.
However, in the lab, clinically speaking, it’s easier to track heparin via PTT and to follow up with warfarin via PT.
An alternative acronym to remember immunoglobulins could be GAMED
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Why do we get INR from PT and not from PTT?
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