Limitless Replicative Potential of Cancer Cells | Immortal Cancer Cells

Hello everyone, In this Video I will teach about limitless Replicative potential of Cancer cells.
I will include following aspects of Immortal Property of Cancer cells.
00:05 - Introduction
00:34 - Molecular Basis of Cancer Recap
02:14 - Factors Responsible for Immortality of cells
02:50 - Loss of senescence by Cancer cells
04:38 - Loss of Mitotic crisis by Cancer cells
08:50 - Self Renewal capacity of Cancer cells
Hope You will Enjoy watching this Video!
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4:06
Shouldn't it be at a hypophosporalated state? so that it binds to E2L, hence prevents the transcription of genes like cyclin E?