Cloning animals - Dolly the sheep - GCSE Biology (9-1)

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  • Опубліковано 27 вер 2024
  • This video is for Edexcel IGCSE Biology 9-1 but is relevant for many GCSE Biology courses. It covers these specific objectives from the syllabus
    5.19B Describe the stages in the production of cloned mammals involving the introduction of a diploid nucleus from a mature cell into an enucleated egg cell, illustrated by Dolly the sheep.
    5.20B Understand how cloned transgenic animals can be used to produce human proteins.
    You can download a teaching PowerPoint for this topic here: www.mrexham.co...
    Or one for the whole course here: www.mrexham.co...
    I also have a TES Shop here: www.tes.com/te...

КОМЕНТАРІ • 84

  • @kalleruuska7163
    @kalleruuska7163 4 роки тому +10

    I wanted to know more about the Dolly sheep and this was the simplest and easiest explanation to understand. Thank you!

  • @chloes.editing6492
    @chloes.editing6492 3 роки тому +10

    Wow thank you so much! I was struggling to understand this concept and I watched your video and I understood it perfectly thank you thank you thank you

  • @bennguyen1313
    @bennguyen1313 5 років тому +8

    Has the Yamanaka technique superseded the Dolly method (transferring the nuclear dna of a somatic cell to an unfertilized oocyte cell)? If not, when is one technique more applicable?
    Since four of Dolly's sisters didn't suffer the same fate... Dolly's early death at 6 years old, is often attributed to a viral-cancer, not related to the cloning procedure. But didn't Dolly also have advanced arthritis and CVD for such a young sheep?
    For example, some suggest that Dolly retained the epigenetic aging signature of the donor sheep.. her telomeres were much shorter than her chronological age would have predicted. Has the connection between cloning / teleomeres / and life-span been established?
    On the Life Scientific Podcast, Ian Wilmut mentions that sperm would normally signal to the egg to start dividing, but in this cloning technique, an electric shock to the egg is used! He also says that while all the genetic information came from sheep #1, there are factors in the egg (sheep #2) that change the expression of that DNA! However, I wonder how much influence the *environment* (sheep #3's horomones, stress, etc) also has over the DNA!

  • @nellsummers7921
    @nellsummers7921 Рік тому +1

    where's the subtitles

  • @amanuelyirdawteshome6353
    @amanuelyirdawteshome6353 Рік тому +2

    Short but perfect

  • @angelitawansa6533
    @angelitawansa6533 Рік тому +3

    please i have a simple question, instead of the nucleus from 1 being put in the egg cell of 2 them into the surrogate 3, why didn't they put an egg cell of 1 straight into 3?

  • @FalGamingHD
    @FalGamingHD 3 роки тому +7

    Wow thank you so much my g, cold 🥶

  • @jayferrier3298
    @jayferrier3298 3 роки тому +13

    cheers for the sick content brotato, its pretty lit🥶😈💯

  • @leangsothyro5301
    @leangsothyro5301 Рік тому

    why do we need 1 more sheep to put the the embryo in we can just out it in the second once

  • @johnganiron8486
    @johnganiron8486 2 роки тому +1

    Why did the biologist pick a sheep to clone?

  • @DaRyteJuan
    @DaRyteJuan 4 роки тому +3

    A very dignified video. Thank you.

  • @Versatilad
    @Versatilad Рік тому

    The link is missing! How was the egg fertilise?

  • @srworship8821
    @srworship8821 4 роки тому +8

    Thank you - This was really helpful!!

  • @learav717
    @learav717 3 роки тому +1

    Isn't it the same if you just use the egg cell of sheep number 1? Why was it needed to enucleated the egg cell of sheep number 2 when you could just use the full egg cell of sheep number one (which already has the dna of sheep 1) or enucleate the egg cell of sheep 1 and fuse it with the dna which would be extracted from another cell of sheep 1? Also why is it needed for the new cell, after its fused, to be implanted in a 3rd sheep?

    • @BANANA-go5oq
      @BANANA-go5oq 3 роки тому

      The egg cell has a random mix of genes due to meiosis, not the full genome.

    • @farhanahmedheathland5923
      @farhanahmedheathland5923 2 роки тому

      ua-cam.com/video/1Gl7UQhGtCA/v-deo.html

  • @themoralshow902
    @themoralshow902 2 роки тому +2

    Thank you❤️😊
    From Sri Lanka 🇱🇰😍

  • @birdie7344
    @birdie7344 Рік тому +1

    thank you so much!

  • @joshua5838
    @joshua5838 4 роки тому +2

    Can we actually bring back extinct animals?

    • @Wizlingss
      @Wizlingss 3 роки тому +2

      Yes unless if you have a reproductive cell sample of a female and male full preserved

    • @farhanahmedheathland5923
      @farhanahmedheathland5923 2 роки тому

      ua-cam.com/video/1Gl7UQhGtCA/v-deo.html

  • @jonassalem9675
    @jonassalem9675 2 роки тому

    why does it have to be an egg from another sheep?

  • @sandhyaedirisinghe2247
    @sandhyaedirisinghe2247 3 роки тому +1

    good thanks Mr.

  • @itxscientist6225
    @itxscientist6225 4 роки тому +1

    Well explained

  • @djamilaaaxo
    @djamilaaaxo 5 місяців тому

    1:22 / 4:10

  • @mandokabazo1826
    @mandokabazo1826 5 років тому +6

    Very good video

  • @sarunkrishnan9435
    @sarunkrishnan9435 2 роки тому

    Sooo cool

  • @alexcatanescu3075
    @alexcatanescu3075 3 роки тому

    fanks luv

  • @x_r_j_w
    @x_r_j_w Рік тому

    who got sent here for R.E

  • @mahirfoisal1992
    @mahirfoisal1992 3 роки тому +1

    ahhhh why british

  • @Hasan-hc5de
    @Hasan-hc5de 4 роки тому +5

    Had an exam. Thanks

  • @rukukaru2450
    @rukukaru2450 3 роки тому +2

    Thank you for all the pictures! I would get lost without it lol

  • @TheEarthCreature
    @TheEarthCreature Рік тому

    Can animals 1 and 3 be the same animal, theoretically? As in, could an animal birth its own clone?

  • @quranwilliams7469
    @quranwilliams7469 4 роки тому +1

    Who has been sent by class 7a

  • @gigigaga666
    @gigigaga666 2 роки тому

    Hello Mr. Exham, i was curious if it is possible to crispr gigantism into the dna?

  • @yusrxn
    @yusrxn 4 роки тому +1

    THANK YOU THANK YOU THANK YOU !!

  • @fizzymizzy_
    @fizzymizzy_ 10 місяців тому

    that dolly pun was great

  • @gangasenthilgangasenthil7825
    @gangasenthilgangasenthil7825 4 роки тому +4

    Your the best and genius

  • @gazey
    @gazey Рік тому

    Man…why don’t I have this topic on my gcse biology textbook

    • @abdulazizmohammed2515
      @abdulazizmohammed2515 Рік тому +1

      wrong syllabus then tf are you doing here

    • @gazey
      @gazey Рік тому

      @@abdulazizmohammed2515 because i enjoy learning it? do i have to have it for my gcse to learn?

    • @abdulazizmohammed2515
      @abdulazizmohammed2515 Рік тому

      @@gazey bro you make no sense i swear you literally said that you cant find this topic in your textbook which means that your following the wrong syllabus and if you take your igcse exams seriously like everyone else you would know not to waste time you never said nice video or this is intreasting literally what you said was why cant i find this topiic on my textbook....

    • @gazey
      @gazey Рік тому

      @@abdulazizmohammed2515 it was a rhetorical question…

    • @gazey
      @gazey Рік тому

      @@abdulazizmohammed2515 I’m doing coordinated science which doesn’t have this in its syllabus

  • @rayanna9550
    @rayanna9550 2 роки тому +1

    This video precisely answered my questions about Dolly (^_^). BTW, can I know what app (or online website) was used for removing the background of the person speaking?? I really need if for my school project. Thank you!

    • @khizarhayat8777
      @khizarhayat8777 2 роки тому +1

      It is called a green screen

    • @farhanahmedheathland5923
      @farhanahmedheathland5923 2 роки тому

      ua-cam.com/video/1Gl7UQhGtCA/v-deo.html

    • @calvin..
      @calvin.. 2 роки тому +3

      @@khizarhayat8777 LMAOOO

    • @calvin..
      @calvin.. 2 роки тому +2

      just use something like greenscreen on zoom and like record it then use and editing software and add urself to the video.

  • @Urban_Explorerrr
    @Urban_Explorerrr 4 роки тому

    Nice video. Love from India. :-)