G0 Phase of Cell cycle | Why cells enter a G0 phase? | Cell cycle | Animated biology with ARPAN | G0
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- Опубліковано 6 вер 2020
- This video describes many important questions regarding G0 phase of cell cycle:-
why cells enter G0 phase?
Is Go phase is common for all cell types?
How cell can exit a G0 state?
What is the significance of entering Go state?
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What is going to happen if the brain cells are not arrested in G0 phase?
What are some stimulus that make some of the cells proceed from G0 phase to G1?
Thank you so much for your answer, I'll subscribe
Exiting the cell cycle and entering into Go is a inbuilt genetic program in neuron failing which neurons would keep on dividing and would not mature. Immature neurons cant make functioning circuits.
There is difference between quiescence and cell cycle exit. The quiescence cells might reenter cell cycle ( like many stem cells) if proper growth factors are present in the surrounding.
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This video needs more love, it is very useful but underated
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As a Brazilian I have to say that this is the best video ever I would like to watch to understand that, thank you a lot!!!! great work!
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So how come it is said that neurons don't divide like they don't heal in terms of spinal injury and what not and tgat they can't be replaced, please explain
Helpful
Thanks it was helpful 👏🏻
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Sure !!!
hi,what references you used for this video?
Well explained
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Sir
What are the methods for development of permanent cell line?
Amazing Video :)
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Can cell cycle proceed to s-phase n g2-phase n exit the cell cycle/enters G0 phase?
which stage of cell cycle has same time in both adults and embryo?
Bhai go phase me koi dividing cell at the end of g1 phase jaega na?? Ya mitotic phase ke baad me koi cell quicesent stage mein ja skta hai?
Dono hi possible hai
Will you give me ther name of this refrence book
👉👈🥺 nice explanation
Thanks for your appreciation
Please make video for telomeres
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I will make a video on telomeres
What are the important events that happen in every checkpoint?
Thanks for the question. Please refer to this video for details ua-cam.com/video/Yb4dQuPLgt8/v-deo.html
Also take a look at my cell bio playlist which contains detailed explanation like this.
Dose the cell enter the g0 if there something wrong in it ?
and then will be dead by apoptotic?
I mean that the cell doesn't enter the cycle again??
Yes BMw...if it's a defective cell apoptosis will help removed it or it can also be done through autophagy pathway ....its a complex thing but that's how the body clean up any defect
Why Active Stem Cells has high levels of Histone Metilation, and Quiescence Stem Cells has low? It should be the opposite if their chromatine is not active. I dont understand that.
Actually I need one entire video to explain it...its complicated but its true
Histone in the methylated state keeps the DNA transcriptionally inactive, so high methylation only keeps those genes active which are required to re-enter the cell cycle and rest of the genes inactive...
The Quiensence stem cells having less histone methylation have most of the genes in active state which maintains the multipotent nature of the cell
This might be the reason i guess..
What happens if the cells in the G0 phase got any of mutations. Will it lead to cancer. Or not?
Depends on the type and location of mutation
When they enter the g0 and never go back like the irreservable how it does affect the organism??
Depends on which cell it is. For example neurons are in Go but they do their job properly
Did you ever happen to post another video of "how the cell can exit a G0 state?" @animatedbiologywitharpan
Nope....but should be making one....thanks for the suggestion
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@@animatedbiologywitharpan if you do, I would love to watch and understand G0 more! I would be happy to share your channel! Thanks for the fast reply!
biosensors? messaging u for the last 2 months
Is it possible for the embryonic cells to be in G0?
Embryonic cells need to divide rapidly for growth . Generally they are not in Go
@@animatedbiologywitharpan Thank you so much!!
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Janine Maat GALDO: yes ofcourse its possible, this affect their pluripotency but under normal condition it should not happen
1)G0 Phase exit the cell cycle or suspend/temporary pause cell cycle?
2)G0 phase. The process occurs at the end of which phase.
Plz reply bro
Cell can enter into Go phase while they are passing through G1 phase( before restriction point ).
Go phase could be both permanent or temporary
@@animatedbiologywitharpan when its permanent how it does affect the organism?
was there an eagle at around 7:53
Yes
why a cell that has just completed cytokinesis might enter G0 phase instead of G1 phase? hehehe
Let's say at this point growth factor is not present or let's say the internal clock is instructing to exit cell cycle