Tablet Compression Defects | Reasons & Remedies Of Tablet Compression Defects
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- Опубліковано 23 лют 2024
- Powders or granules are compressed using specific tolling on a compression machine to manufacture tablets.Different manufacturing defects are observed during the process of tablet compression.The sound knowledge of tablet compression defects along with reasons & remedies is very essential for all the professionals working in pharmaceutical industries.
The reason for tablet compression defects may be related to the formulation or it may be due to the compression machine tooling or its adjustment.
The most commonly observed tablet compression defects are given as below
Tablet Capping
Tablet Lamination
Tablet Sticking & Picking
Weight variation
Friability Problem
Low Tablet Hardness
Double impression
Black spots on tablets
Rat holing
In this video you will learn the following,
Reasons & remedies of tablet Capping & lamination
Reasons & remedies of tablet sticking & picking
Reasons & remedies of tablet weight variation
Reasons & remedies of tablet Friability problem
Reasons & remedies of low tablet Hardness
Reasons & remedies of tablet black particles
Reasons & remedies of rat holing
Reasons & remedies of double impression
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Masha Allah nice video brother well done 👍💯💯💯💯💯💯💯💯
very informative. dr sahb
Kindly sir one deep video about the introduction to pharmacology please ❤❤❤❤❤
High pressure of compression machine (tablets compressed at high hardness) will result in lower friability not higher friability, kindly correct.