Tablet Compression - In process checks in Pharmaceutical industry l Interview Question and answers

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  • Опубліковано 13 січ 2024
  • Compression - In process checks in Pharmaceutical industry l Disintegration test l Friability l Interview Question and answers
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    Questions covered:
    Q. What are the important in-process checks performed during tablet compression process ?
    Q: Which USP chapters are referred for compression in-process checks ?
    Q. What should be the frequency for in-process checks done during compression process ?
    Q. What is the purpose of in-process checks during tablet compression ?
    Q. What is the purpose of the disintegration test in tablet compression process ?
    Q. Explain the difference between disintegration and dissolution testing?
    Q. Can you describe the apparatus used in the disintegration test, and how does it function ?
    Q. What are the key parameters or values as per USP Chapter No.701 for disintegration test ?
    Q. How is the disintegration test performed, and what are the key steps involved?
    Q. What is the purpose of the Friability test in pharmaceutical industry ?
    Q. For how many rotations we should rotate friability test apparats and at what RPM ?
    Q. How many tablets we should take for friability test?
    Q. Describe the procedure for conducting a friability test on tablets ?
    Q. Why dedusting is important prior to friability test?
    Q. What is formula for calculating friability and what is acceptance criteria ?
    Q. Which units are commonly used for measuring tablets hardness ?
    Q. Which defects can be identified during visual inspection of compressed tablets ?
    Q. How many tablets shall be considered during initial setting of compression machine for weight variation testing ?
    Q. What is weight variation limit as per USP?
    Q. What is the operating principle of a metal detector used in tablet compression ?
    Q. Why is it essential to monitor compression force during tablet production ?
    Q. With what pieces metal detector is challenged ?
    Q. What is evaluated during tablet dissolution testing ?
    Q. What is relation between tablet thickness and tablet hardness during tablet compression process ?
    Q. What should be the action plan taken in case we miss the in-process test frequency or out of limit result observed ?
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    Keywords to find this video:
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