Adenylyl Cyclase - cAMP Pathway || Gs and Gi Protein Pathway

[@meifukusha2465]

You made medical concepts easier to understand. More powers to you sir.

[@sidraiqbal2833]

Literally the best video to knw how actually this G protein couples receptors work.. no need to see other videos on ths topic..thanks a dozen

[@NonstopNeuron]

Most welcome. Please share the channel with yours contacts to support us. Thank you. 😊

[@Abbas2003io]

Thanx from Iraq 🇮🇶
Pharmacy student

[@LucasFerreira-dv6ol]

I'm stunned how didactic this video is ! Amazing ! Keep the good job dude, I appreciate your effort !

[@NonstopNeuron]

Yes I will. Thank you 😊

[@Y26643]

Thankyou for the detailed explanation. The animated video made it even more fun to watch and understand better

[@yasho6711]

Sir Thank you so much for this video. This helped me lot while I was confiused with biochemistry examination. Thank you agin and again.we need more videos♥️

[@AshBlanx]

simple yet effective explanation. thank you

[@jonathanfargalla5427]

so well explained, we can't thank you enough!

[@salmahassan7487]

Your videos are really easy to understand, interesting and helpful. Thank you so much for making such amazing videos🤩

[@ZeeshanAli-vp1pq]

Outstanding work 👍👍

[@syb5009]

Fantastic illustrations and explanation

[@mr.authorallinone4706]

Great explain about g protein coupled receptors😊😊😊. Thanks sir

[@jieyang6905]

Amazingly helpful. Thank you so much~

[@يقينيباللهيقيني-ك8ك]

راجع جدا ❤ شكرا لك

[@darshanbhirud3354]

Thank you what a animation keep doing sir

[@vitoria96634]

Clear and practical video, thank you so much

[@NonstopNeuron]

Welcome 🤗

[@mmuh197]

this is amazing you made it very simple and understandable
thanks for your efforts

[@aedejoseph5903]

Thank you so very much, sir. You've helped me to understand this concept really well

[@SalmanKhan-eh4gg]

🤩 I am going to in love with your lecture

[@zakirzak1494]

Thank you, very well explained and had nice animations :)

[@ammarasattar7809]

Thank you so much this video is so helpful for me to understand the physiology 🧡🔥

[@easycode924]

I wanted this concept, thanks 🙏😇

[@asimzubair55]

Thanks for sharing. Its wonderful video

[@virginiayoussef]

Many thanks for your amazing explanation, no one explained it as you did , would you pls allow a transcript to show below the video for more focus , thank you

[@NonstopNeuron]

Captions are added to almost all the videos on the channel. You can turn them on or off as per your preference.

[@ammu9642]

Sir we need more and more Vedios like this tq so much sir

[@NonstopNeuron]

Yes. I am working on it

[@ammu9642]

@@NonstopNeuron 👍

[@harryseverusgranger255]

absolutely amazing video!!!

[@juallee2711]

excellent explanation!!! thank you so much!!

[@lipsaartdesigns5668]

So interesting sir

[@eshragaabdallahmohammedahm387]

It's amazing 👏
Thanks so much

[@wycliffenyandika9017]

Nice! I like the explanation

[@chancelorhardy9893]

I have a quick question; if the alpha subunit has ATPase activity, what prevents the conversion of ATP to ADP before it can activate the Adenylyl Cyclase?

[@NonstopNeuron]

Hummm... Interesting question. Honestly I don't know the answer. It may be the association with the receptor itself or with beta-gamma complex. Or maybe the activity is intrinsically slower than the speed with which it goes to Adenylyl cyclase and activates it. But as a medical person we don't need further detail to understand other concepts. I have already covered every detail necessary to the best of my knowledge and understanding. So although the question is interesting, I am not excited to find out the answer. I am happy with my assumption 😝

[@NonstopNeuron]

I am also assuming that you are a medical student. If you are a researcher or something, then you might need to go into further detail.

[@Abhisheksingh_102]

Underrated channel.

[@NonstopNeuron]

I need your support to grow. If you feel this channel deserves more, please share videos to all your contacts.It helps a lot in many ways. Thank you so much.

[@uttamghosh503]

Awesome ❤ most helpful

[@keurinrin16]

Your illustrations are sooo cute🤣🤗🤗

[@GSN7811]

thank you so much my dear god...teach us more

[@muhammadatif7441]

Amazing 😍
Mashaallah

[@hayaalhassawi7091]

Brilliant 👏🏻

[@meifukusha2465]

Thank you so much.

[@saragadamramdiwakar8578]

Very usefull lecture And very cleanly explained Thank u sir😍

[@mmmpr2261]

Thank you, so much !

[@vaibhavi5469]

Really it's very good 😃😻

[@amiyodas6908]

Clear understanding ❤

[@galmaankhan8338]

Thank you so much sir.

[@NonstopNeuron]

Most welcome

[@prathz1065]

Very well made👏

[@PhoebeClarke-f2h]

Amazing!!!!

[@FatimaRaja-zf1ke]

❤❤very interesting

[@rinaislam6428]

Awesome!!!

[@sairaahsan9019]

Amazing video

[@samsciences5966]

Nice work

[@tresasebastian9909]

Thank u so much sir.....👏

[@zainabfarooq5263]

Thank you

[@nabeelafarheen8224]

💖💖superb sir

[@بسمهأمل-ث3ز]

Wow amazing

[@rupsonteron9512]

Thanks a lot

[@GoodKnight5252]

how does sequstation of Ca into the sER cause increase in myocyte contractility? isn't it the opposite?

[@NonstopNeuron]

With sequestration more calcium can be released in cytosol with each impulse. So the contractility increases

[@pijushsingha9232]

Sir with the effect of adrenaline and noradrenaline the calcium ions will come out from sarcoplasmic reticul into the cytosol but u just said that it sequesters the ca2+ions into the sarcoplasmic reticulum

[@NonstopNeuron]

Yes, both statements are true. There is no conflict between the two. Under the influence of these hormones the SER becomes more loaded with calcium i.e. more Ca is sequestered in SER. This is at the basal level. And as this sequestered Ca is released during each impulse, more Ca is released. And this, as stated is during impulse. I hope it helps

[@catherinesakeena1099]

Best💯🙂‍↕️

[@shahiimran3365]

Thnq u sir ❤️

[@nomeshsahu2816]

Thank you so much for made easy 😁...

[@abhishekkashyap-iw9ig]

Superb

[@NonstopNeuron]

Thanks😊

[@mudasirahmad446]

Very helpful

[@shiprasingh2143]

It really helped me a lot

[@nazaninsherafati3510]

❤📚thanks

[@nipamonalisa7286]

Thank you thank you

[@funnymanandguy]

Good video!

[@NonstopNeuron]

Thank you

[@KanuPriya-dn1ul]

Very very useful❤️

[@NonstopNeuron]

Glad it was helpful!

[@DrApocalyptus]

Well communicated

[@Gabin._.]

thx u smmm

[@liliadriss7944]

رائع جدا شكرا جزيلا لك

[@saragadamramdiwakar8578]

Sir,small request - Plz make pnemonics to remember drugs🙏🙏

[@NonstopNeuron]

Instead of mnemonics, I try to explain the core concept in a memorable way. You can consider visual metaphors as memory tricks. That being said, I do get thoughts of making mnemonics but if I ever do that, it will be secondary to my main way of teaching.

[@nishantsen6820]

Beta gamma subhunit remain attached to gprotein?

[@NonstopNeuron]

No

[@nishantsen6820]

@@NonstopNeuron okay and one more dobut why receptor use more than one g protein?

[@NonstopNeuron]

To integrate incoming signals. Watch this video: ua-cam.com/video/aIZQ3ker0KE/v-deo.html
You will get the idea.

[@nishantsen6820]

@@NonstopNeuron okay thanks

[@louiza2245]

💗💗💗

[@loveall022]

❣️

[@hellyerlolipops5186]

How :0

[@samionita2008]

Thank you