cAMP - ATP, ADP, cAMP - Adenylate cyclase - Protein Kinase A - G-protein, Cell Signaling - Physio

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  • Опубліковано 13 гру 2024

КОМЕНТАРІ • 121

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 роки тому +5

    💊🤷‍♂️ Cardiac pharmacology is on SALE:
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  • @mikkit876
    @mikkit876 2 роки тому +10

    I have epilepsy and miss a lot of my lectures due to seizures, your videos have helped SO much in me being able to learn biochemistry and medicine. Thank you! You make it so entertaining as well

  • @alaynaguzzi2017
    @alaynaguzzi2017 3 роки тому +20

    You have brought forth joy and passion that I have been lacking this semester. Thank you.

  • @Chris-tg8gr
    @Chris-tg8gr 2 місяці тому +2

    "Pharmacology makes perfect sense once you understand what the flip you're talking about!...." I felt that!!

  • @ficklepepper
    @ficklepepper 3 роки тому +5

    EXCELLENT resource to put concepts together of what 2 textbook, paid courses and expensive books can offer. After watching your video I feel that I can practically track where the process begins and ends forward and backward. Forever grateful. Thank you

  • @aydaabdolmanafi
    @aydaabdolmanafi 11 місяців тому +4

    In the first three minutes i got all my confusion solved, the confusion that has happened after reading a university pamphlet for hours nonsense!

  • @Veteran365
    @Veteran365 2 роки тому +4

    Holy shit!! You are an amazing teacher!

  • @MalynLaReina
    @MalynLaReina 3 роки тому +2

    Of all the videos and articles I read this made the most sense. Thank you for breaking it down, and making it fun with your side comments. Really helped me grasp the concept!

  • @jamierayevalmores3109
    @jamierayevalmores3109 3 роки тому +5

    i love your videos. it makes pharmacology fun and a "lil bit" easier. please keep making more. you're the best

  • @lisagonzalez2902
    @lisagonzalez2902 4 роки тому +9

    I've been searching for videos on cAMP, cGMP, and found some very good ones but I wanted to see if you also had a video on this subject, and I found it! Thanks for your effort. Funny, repetitive, really makes me understand better.

  • @paulakiaraluna1969
    @paulakiaraluna1969 4 роки тому +3

    I love your videos so much!!! I am preparing for my MCATs and I watch your videos to deeper learn topics. Please keep making more! Thank you for all your help!

  • @saraxcardoso
    @saraxcardoso 4 роки тому +4

    You are so funny and you expalin these concepts so well and so clearly! I love this video, thank you sooo much 💖🙌🏼

  • @najumudhina.m.k3966
    @najumudhina.m.k3966 4 роки тому +12

    Your videos are really unique, its reflecting your hard work and by God Grace, you will reach million subscribers soon

  • @sunnrayy11
    @sunnrayy11 3 місяці тому +2

    this mannnnnnnnnnn is great

  • @santoszinga2617
    @santoszinga2617 3 роки тому +3

    I really love this video,that makes sense .

  • @Afshu97
    @Afshu97 2 роки тому +2

    Nice explanation thank you so so so much

  • @Southerngrl
    @Southerngrl 4 роки тому +3

    I bet the plaquenil video wld get you lots of views esp with zpac! Even though it’s “off label” hard for lay pll to understand the ramifications of these meds! You can explain it so much better for us all!

  • @ayeshamuhammad6553
    @ayeshamuhammad6553 4 роки тому +2

    Your videos are simply amazing. I have a much better understanding of many topics including cAMP!

  • @luciararocha
    @luciararocha 3 роки тому +1

    I can't believe I finally understood this!!!! Thank you so much 💓

  • @nermeengamal5441
    @nermeengamal5441 3 роки тому +1

    The way you talk so unique, funny, beautiful. ❤

  • @lisagonzalez2902
    @lisagonzalez2902 4 роки тому +4

    I noticed a mistake at 13:05. You say Ca+ channel blockers 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞 cardiac contractility, however, the drawing states that it 𝐝𝐞𝐜𝐫𝐞𝐚𝐬𝐞𝐬 (this is correct).

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 роки тому +2

      They decrease contractility.
      Thank you so much for correcting me.

    • @lisagonzalez2902
      @lisagonzalez2902 4 роки тому

      @@MedicosisPerfectionalis I have a question! I'm not very clear on the cAMP effects on Angiotensin? Doesn't it inhibit this process (therefore, causing vasodilation)? I've tried watching that part a few times but I don't understand. Please, enlighten me!

    • @lisagonzalez2902
      @lisagonzalez2902 4 роки тому

      Does cAMP cause both vasoconstriction and vasodilation? Beta-agonists increase cAMP, therefore causing vasodilation. But Beta-blockers cause vasodilation by decreasing cAMP because of the A-T pathway? Why doesn't cAMP *only* cause dilation/relaxation in smooth muscle?

  • @nhhao_medi
    @nhhao_medi 11 місяців тому +1

    i love the way you make it ez to understand
    From Vietnam with luv ❤

  • @cynthianyanda3842
    @cynthianyanda3842 2 роки тому

    Thank you so much! I've been stuck confused and didn't want to watch this video coz it's longer than the other cAMP UA-cam videos by like 15 minutes. But I was confused even after watching them so I wasted my own time and here I am.

  • @farhaelsharif9317
    @farhaelsharif9317 3 роки тому +1

    thank you for this video its perfect you're saving lives

  • @rania0.1
    @rania0.1 Рік тому +1

    ❤ love your vibes How to explain and I love your voice more

  • @markusguerrero9593
    @markusguerrero9593 3 роки тому

    This is amazing. Thank you!

  • @ComPasPharm
    @ComPasPharm Рік тому

    Thx. Beautifull lecture!!!

  • @sama_albairmani
    @sama_albairmani 3 роки тому

    INCREDIBLY AMAZINGGGGG

  • @monika246
    @monika246 4 роки тому +1

    Wowwww...just loved it

  • @anahmoon522
    @anahmoon522 2 роки тому

    I laughed when you said "it's common sense" 🤣

  • @jesusbrownies
    @jesusbrownies 3 роки тому

    Everything is soo clear after watching this
    Thank you so muchhh

  • @muhammaduwais5323
    @muhammaduwais5323 4 роки тому +2

    Really helpful

  • @Robert___3f
    @Robert___3f 5 місяців тому

    Pessimistically acknowledging the power of a smile.

  • @gamagarcia3037
    @gamagarcia3037 Рік тому

    just of curiosity are those receptors receiving information outside the membrane which because of the signal they RECEIVE, the START the process of producing the cAMP? , are they the G protein couple receptors?

  • @danagreenberg945
    @danagreenberg945 4 роки тому

    this was perfect

  • @doctorgvlog
    @doctorgvlog Рік тому +1

    Lovely sir

  • @a30694
    @a30694 3 роки тому +1

    cAMP acts on smooth muscle of blood vessels and cause vasodilation and a decrease in bp. On the other hand it increase angiotensin ii and aldosterone and causes vasoconstriction and salt and water retention and increase bp. So which is the predominant effect?
    Please help me out.

    • @tylerwilliams6882
      @tylerwilliams6882 3 роки тому

      did you find an answer to this? I'm wondering the same thing

  • @calvinrich363
    @calvinrich363 3 роки тому

    if you use b-blocker, which means b1 receptor is not working, so no stimulation of Gs, so no cAMP. no cAMP means contractility is decrase and vasoCONSTRICTION, no????
    means b-blocker can cause vasoconstriction leads to increase BP
    please correct me if i misunderstood

  • @sathvikgowda1348
    @sathvikgowda1348 2 місяці тому

    Hi...at 12:10 you say the cAMP causes vasodilation and decrease BP and also you say..via RAAS pathway vasoconstriction occurs and BP increases. Which one is predominant?

  • @JoyceGem
    @JoyceGem 3 роки тому +1

    HAHAHAHA your wit tho 🤣🤣 tbh this is the way I study too. Lmao "this is common sense" HAHAHA

  • @georgep.7492
    @georgep.7492 4 роки тому

    I am not even studying pharmacology this year, but this was nice

  • @olaabdallah3607
    @olaabdallah3607 Рік тому +2

    Amazing video ❤
    Btw love your accent, are you egyptian? 😂

  • @aroor1785
    @aroor1785 2 роки тому

    Is there a place i can get the transcript of this lecture from ? 18 minutes video made me understand so much about antiplatlets therapy, and some of the most common shock hf interventions we take ,, and even aminophyline toxicity .. thank u man

  • @ضحىيوسف-ع2ت
    @ضحىيوسف-ع2ت 4 роки тому

    Thank u for this video and please teach us the biochemistry

  • @Dr_fonesz
    @Dr_fonesz 4 роки тому

    Very informative.

  • @ABC-fv7ow
    @ABC-fv7ow 2 роки тому

    Superb 👌

  • @rathodnehal2869
    @rathodnehal2869 4 роки тому

    can you make video on cGMP mediated vasodilator

  • @frodobeutlin4368
    @frodobeutlin4368 4 роки тому +1

    you son got a new customer ;)

  • @arunaacharya3849
    @arunaacharya3849 2 роки тому

    PDEs are also of different types...There is PDE1,2,3,4.Could u shed some light on the location?..are they all present in the cytoplasm?

  • @banjitkalita8556
    @banjitkalita8556 3 роки тому

    How cAMP contract heart muscle and dilate smooth muscle??

  • @sonya1500
    @sonya1500 3 роки тому +1

    I am a simp for medicosis perfectionalis.

  • @Srun-p2b
    @Srun-p2b Рік тому

    Hello ! Anyone can explain me why a2 receptor -> Gi pathway -> low c AMP, but it cause relaxation?
    (Source: b. α2 Receptors
    are located on sympathetic postganglionic nerve terminals (autoreceptors), platelets, fat cells, and the walls of the GI tract (heteroreceptors).
    often produce inhibition (e.g., relaxation or dilation).
    Mechanism of action: Gi protein, inhibition of adenylate cyclase and
    decrease in cyclic adenosine monophosphate (cAMP). )

  • @bealambwouldya
    @bealambwouldya 4 роки тому

    This easier to understand then my teacher 💀

  • @dianalynvillanueva1216
    @dianalynvillanueva1216 3 роки тому

    this is so cool. hahha thanks for yhe good pneumonic 😎

  • @black.beerd.gaming
    @black.beerd.gaming 2 роки тому

    completely savagery, I'll be rewatching this video for fun

  • @immadisarojini2775
    @immadisarojini2775 3 роки тому

    Super

  • @polarispolaris1705
    @polarispolaris1705 Рік тому

    شرحك ممتاز

  • @artbylupiv
    @artbylupiv 3 роки тому

    Man you are asm just awsm

  • @juliandionne7209
    @juliandionne7209 2 роки тому

    great

  • @lujnas
    @lujnas 2 роки тому

    god, his voice..........

  • @elizabethrouse4182
    @elizabethrouse4182 2 роки тому

    you misspelled messenger ;-)

  • @hemanth.sgowda702
    @hemanth.sgowda702 4 роки тому +2

    👏👌

  • @thinkpositive8328
    @thinkpositive8328 2 роки тому

    😎😎

  • @aroor1785
    @aroor1785 2 роки тому +1

    Convert it into trash called degradation products ahhahahhahahahhahahhahhahahhahahahahhahahahahhahahahah

  • @evaneckhart9648
    @evaneckhart9648 2 роки тому

    L accent